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The map label for this gene is yngJ [H]

Identifier: 114800547

GI number: 114800547

Start: 1191582

End: 1192628

Strand: Direct

Name: yngJ [H]

Synonym: HNE_1184

Alternate gene names: 114800547

Gene position: 1191582-1192628 (Clockwise)

Preceding gene: 114798570

Following gene: 114799882

Centisome position: 32.16

GC content: 66.28

Gene sequence:

>1047_bases
ATGGAATTTGCACTTTCTGAAGACCAGCGCATGCTGCAGGACAGCCTCAAGGGCGTTCTGGGCGAGGCGGCACATCTTGA
TCGTATACGGAAAATCGCGGCGGGCGAGACCGGCGAAGGCGCGGCGCTGGACGCGGCGCTTTCTGAGTTTGGGCTTTCGG
CGCTGATGGTGCCTGAAGCGGCGGGCGGGCTTGGGCTGGGGGCGCTGGACGCGTGCCTGGTGCAGGAGGCGCTTGGTTAT
GATGTGGCGCCATCGCGCTTTCTGGCGACGGCGGTGGCGGCCAAGCTGCTGGCGGGCAAGCCGGATGTGCTGGGCGCCAT
TGCGGGCGGCGAGGCGACGTTTGGGCTTGCGCTGACGGAGCTGTTCTCGCGGCGCGACGGGGCGGGTGTTGAGCTGAAAG
GCGGCAAGCTGAGCGGCAAGAGCCTGCTGGCACAGTCCGTAGACGGCGCAACGCATATCCTCGTGGCGGACACGGCCGGG
GCGGTGCATTCCGTGGCGGTGGGCAAAGCCAGCGTTACCGTGATGCAGACCATTGACCGGACACGGACGTTCCATGAGGT
GGCGTTTGACGGGGCTGAGCCGCTCGTCAGCGTGACGCCAGAGGCTGAGGCGATTGCCTTTGCGCGGCTGCTGGTGGCGG
CCGATACGCTCGGGACGGCGCAGGCGATGATCGACAAGGCGGTCGCCTATGCCAAGGAGCGCCAGCAGTTTGGCCGGGTG
ATCGGTTCGTTCCAGGCGGTGAAGCATATGTGCGCCGAGATGGCCGCGAAGCTGGAGCCGGCGCGGGCGCTGATCTGGCA
TGCCGCGCATGCGCTCGACATTGGCGACGCCGAAGGGCCGATGATGGCGACCCTGGCCAAGGCGCATCTGGCAGAGGTGG
GCACCTTTGTGGCGCGCACCTCGACCGAGGTGCATGGCGGGATGGGGTTCACCGATCTGGTCGGGCTTCATTACTGGTAT
AAGCGGATCGGGGTGAACCGGCAGTTGCTGGGCAGCCCGGAGCAGACGCGCCAGACCGCGGCAGAATTGCAAGGACTGGT
TGTGTAA

Upstream 100 bases:

>100_bases
CTGATCATCGGCGGGGGCACCGCGCAGATCCAGAAGAACATCATTGCGGAACGCGGGCTCGACATGCCGCGTGAGCCGAA
GCTGGCGAAGGTATAGGCTC

Downstream 100 bases:

>100_bases
TCATCCGTAAAGCTGAATAATGCAATCAAGCCGCGAGTTTTGACTTGTGGTTAACCCTGAGTTGTGCAATCAAATCCATA
TTATACACGCACTGGTCGTA

Product: acyl-CoA dehydrogenase family protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MEFALSEDQRMLQDSLKGVLGEAAHLDRIRKIAAGETGEGAALDAALSEFGLSALMVPEAAGGLGLGALDACLVQEALGY
DVAPSRFLATAVAAKLLAGKPDVLGAIAGGEATFGLALTELFSRRDGAGVELKGGKLSGKSLLAQSVDGATHILVADTAG
AVHSVAVGKASVTVMQTIDRTRTFHEVAFDGAEPLVSVTPEAEAIAFARLLVAADTLGTAQAMIDKAVAYAKERQQFGRV
IGSFQAVKHMCAEMAAKLEPARALIWHAAHALDIGDAEGPMMATLAKAHLAEVGTFVARTSTEVHGGMGFTDLVGLHYWY
KRIGVNRQLLGSPEQTRQTAAELQGLVV

Sequences:

>Translated_348_residues
MEFALSEDQRMLQDSLKGVLGEAAHLDRIRKIAAGETGEGAALDAALSEFGLSALMVPEAAGGLGLGALDACLVQEALGY
DVAPSRFLATAVAAKLLAGKPDVLGAIAGGEATFGLALTELFSRRDGAGVELKGGKLSGKSLLAQSVDGATHILVADTAG
AVHSVAVGKASVTVMQTIDRTRTFHEVAFDGAEPLVSVTPEAEAIAFARLLVAADTLGTAQAMIDKAVAYAKERQQFGRV
IGSFQAVKHMCAEMAAKLEPARALIWHAAHALDIGDAEGPMMATLAKAHLAEVGTFVARTSTEVHGGMGFTDLVGLHYWY
KRIGVNRQLLGSPEQTRQTAAELQGLVV
>Mature_348_residues
MEFALSEDQRMLQDSLKGVLGEAAHLDRIRKIAAGETGEGAALDAALSEFGLSALMVPEAAGGLGLGALDACLVQEALGY
DVAPSRFLATAVAAKLLAGKPDVLGAIAGGEATFGLALTELFSRRDGAGVELKGGKLSGKSLLAQSVDGATHILVADTAG
AVHSVAVGKASVTVMQTIDRTRTFHEVAFDGAEPLVSVTPEAEAIAFARLLVAADTLGTAQAMIDKAVAYAKERQQFGRV
IGSFQAVKHMCAEMAAKLEPARALIWHAAHALDIGDAEGPMMATLAKAHLAEVGTFVARTSTEVHGGMGFTDLVGLHYWY
KRIGVNRQLLGSPEQTRQTAAELQGLVV

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI187960098, Length=312, Percent_Identity=29.4871794871795, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI4557231, Length=312, Percent_Identity=29.4871794871795, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI4501859, Length=120, Percent_Identity=34.1666666666667, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=359, Percent_Identity=27.5766016713092, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=297, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=129, Percent_Identity=31.7829457364341, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=314, Percent_Identity=27.7070063694268, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356377, Length=365, Percent_Identity=26.027397260274, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24646207, Length=137, Percent_Identity=32.1167883211679, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 36110; Mature: 36110

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFALSEDQRMLQDSLKGVLGEAAHLDRIRKIAAGETGEGAALDAALSEFGLSALMVPEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCC
AGGLGLGALDACLVQEALGYDVAPSRFLATAVAAKLLAGKPDVLGAIAGGEATFGLALTE
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
LFSRRDGAGVELKGGKLSGKSLLAQSVDGATHILVADTAGAVHSVAVGKASVTVMQTIDR
HHHCCCCCCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHCHHHHHHHHHHHH
TRTFHEVAFDGAEPLVSVTPEAEAIAFARLLVAADTLGTAQAMIDKAVAYAKERQQFGRV
HHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGSFQAVKHMCAEMAAKLEPARALIWHAAHALDIGDAEGPMMATLAKAHLAEVGTFVART
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
STEVHGGMGFTDLVGLHYWYKRIGVNRQLLGSPEQTRQTAAELQGLVV
CCHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEFALSEDQRMLQDSLKGVLGEAAHLDRIRKIAAGETGEGAALDAALSEFGLSALMVPEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEECCCC
AGGLGLGALDACLVQEALGYDVAPSRFLATAVAAKLLAGKPDVLGAIAGGEATFGLALTE
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHH
LFSRRDGAGVELKGGKLSGKSLLAQSVDGATHILVADTAGAVHSVAVGKASVTVMQTIDR
HHHCCCCCCEEEECCCCCHHHHHHHHCCCCEEEEEECCCCCHHHHHHCHHHHHHHHHHHH
TRTFHEVAFDGAEPLVSVTPEAEAIAFARLLVAADTLGTAQAMIDKAVAYAKERQQFGRV
HHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGSFQAVKHMCAEMAAKLEPARALIWHAAHALDIGDAEGPMMATLAKAHLAEVGTFVART
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
STEVHGGMGFTDLVGLHYWYKRIGVNRQLLGSPEQTRQTAAELQGLVV
CCHHCCCCCHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]