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The map label for this gene is ctaA

Identifier: 114800338

GI number: 114800338

Start: 2417303

End: 2418358

Strand: Reverse

Name: ctaA

Synonym: HNE_2318

Alternate gene names: 114800338

Gene position: 2418358-2417303 (Counterclockwise)

Preceding gene: 114799297

Following gene: 114797444

Centisome position: 65.27

GC content: 66.57

Gene sequence:

>1056_bases
ATGACACCAAGCGCAATTTCCCCCGTTGCCGCAGGCTGGATACGCCGCTGGCTGATCCTTATGGCCCTGATGGTCTATGC
CATCATTCTGGTCGGCGGCGCGACGCGCCTGACCGATTCCGGGCTTTCCATAACAGAGTGGCGCCCTGTCAGCGGCGCGC
TGCCGCCGATGAGTGAAGCGGCGTGGCTGGTGGAGTTCGAGAAGTATCGCGCGACCACCCAGTATCAGCTGACCAATGCG
GGCATGGCGCTCTCCGAGTTCCAGTTCATTTACTGGTGGGAGTGGGGCCACCGGCAGATCGGGCGGCTGATTGGCCTTGT
GGCGGTGGCGGGTTTTGCGTTTTTCGCCTGGCGGCGCTGGCTGGGGCAGGGGCTCGGCTGGAAGCTGGTGGGGCTGATTG
CGCTGGGCGGGCTTCAGGGCGCGATTGGCTGGTGGATGGTGTCGAGCGGCATTGGCGAGACTGAGCGGGTGTCGGTGGCG
CCCTACCGGCTGATGACGCACTTTACGCTGGCGCTGCTTATTCTGGCGGTGATCGCGTGGCTTTGGCTGGACCTTGGACG
GCAGCAGCGGGCCGGGGCGCCGAGGGCGGCGCAGCGGGCGGCGATGGCGCTGATGGGGCTGATCTTCGTGCAGATGGCGG
CGGGCGCGCTGGTGGCGGGGCTGGACGCGGGGCGGACTTATACCGACTGGCCGCTGATGGCGGGGGAGGTGTTTCCCGCT
CATTATATACATGCCGAGCTGGGCGTTCGCAGCTTCTTTGAGGGGCGCGAGGCGACGCAGTTCAATCACCGCCTGCTGGC
CTATGGGCTTTGGGCGGGGAGCCTGGCGGCGGCGTGGGCGTTCCGGAAGACGGATGTGCACCGGGAGTTTGCGTTTCTGG
CGGTGCTGGTTTCCGCGCAGGCGGTGTGGGGCATCCTCACGCTGGTCAATGCTGCCCCGATGGGGCTGGCGCTGGTGCAT
CAGGGGCTGGGCGTGGTGACCACGCTTTGGGCCGTCTACACAGTGTGGCGTGCAGGCGGCCCGAAGACGGTGGCGGAGAT
CAATCCTCCAGCGTGA

Upstream 100 bases:

>100_bases
TTGCGCATGGGCGTGTCTCTCTGTCTTGTGCCGTCGTGTCCGGGCGGGCTGCGACCACAGCGACCCTTGATCGCGGCGCC
CGTCAAGTGATCTAGGCTTC

Downstream 100 bases:

>100_bases
TGGCGCTGGGGTCTACAAAGACAACCTGATGGGTGCCTTCGCTGGTTTCGCCGGCGATGACGACAACGCCGCCCGGATAG
CCGCCGGCGGGGAGTGTGCC

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTPSAISPVAAGWIRRWLILMALMVYAIILVGGATRLTDSGLSITEWRPVSGALPPMSEAAWLVEFEKYRATTQYQLTNA
GMALSEFQFIYWWEWGHRQIGRLIGLVAVAGFAFFAWRRWLGQGLGWKLVGLIALGGLQGAIGWWMVSSGIGETERVSVA
PYRLMTHFTLALLILAVIAWLWLDLGRQQRAGAPRAAQRAAMALMGLIFVQMAAGALVAGLDAGRTYTDWPLMAGEVFPA
HYIHAELGVRSFFEGREATQFNHRLLAYGLWAGSLAAAWAFRKTDVHREFAFLAVLVSAQAVWGILTLVNAAPMGLALVH
QGLGVVTTLWAVYTVWRAGGPKTVAEINPPA

Sequences:

>Translated_351_residues
MTPSAISPVAAGWIRRWLILMALMVYAIILVGGATRLTDSGLSITEWRPVSGALPPMSEAAWLVEFEKYRATTQYQLTNA
GMALSEFQFIYWWEWGHRQIGRLIGLVAVAGFAFFAWRRWLGQGLGWKLVGLIALGGLQGAIGWWMVSSGIGETERVSVA
PYRLMTHFTLALLILAVIAWLWLDLGRQQRAGAPRAAQRAAMALMGLIFVQMAAGALVAGLDAGRTYTDWPLMAGEVFPA
HYIHAELGVRSFFEGREATQFNHRLLAYGLWAGSLAAAWAFRKTDVHREFAFLAVLVSAQAVWGILTLVNAAPMGLALVH
QGLGVVTTLWAVYTVWRAGGPKTVAEINPPA
>Mature_350_residues
TPSAISPVAAGWIRRWLILMALMVYAIILVGGATRLTDSGLSITEWRPVSGALPPMSEAAWLVEFEKYRATTQYQLTNAG
MALSEFQFIYWWEWGHRQIGRLIGLVAVAGFAFFAWRRWLGQGLGWKLVGLIALGGLQGAIGWWMVSSGIGETERVSVAP
YRLMTHFTLALLILAVIAWLWLDLGRQQRAGAPRAAQRAAMALMGLIFVQMAAGALVAGLDAGRTYTDWPLMAGEVFPAH
YIHAELGVRSFFEGREATQFNHRLLAYGLWAGSLAAAWAFRKTDVHREFAFLAVLVSAQAVWGILTLVNAAPMGLALVHQ
GLGVVTTLWAVYTVWRAGGPKTVAEINPPA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=335, Percent_Identity=33.7313432835821, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI17921987, Length=275, Percent_Identity=35.6363636363636, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17536069, Length=324, Percent_Identity=34.8765432098765, Blast_Score=164, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6320989, Length=345, Percent_Identity=34.7826086956522, Blast_Score=174, Evalue=3e-44,
Organism=Drosophila melanogaster, GI19922860, Length=341, Percent_Identity=31.0850439882698, Blast_Score=134, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_HYPNA (Q0BZT0)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_761013.1
- STRING:   Q0BZT0
- GeneID:   4289272
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_2318
- NMPDR:   fig|228405.5.peg.2234
- TIGR:   HNE_2318
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   PPMSEAA
- PhylomeDB:   Q0BZT0
- ProtClustDB:   CLSK2781050
- BioCyc:   HNEP81032:HNE_2318-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 38435; Mature: 38304

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: BINDING 320-320

Signals:

None

Transmembrane regions:

HASH(0x144ace84)-; HASH(0x149f2b58)-; HASH(0x13097850)-; HASH(0x1440e224)-; HASH(0x13fbec84)-; HASH(0x1435c198)-; HASH(0x149de83c)-; HASH(0x14a23c58)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSAISPVAAGWIRRWLILMALMVYAIILVGGATRLTDSGLSITEWRPVSGALPPMSEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEECCCCCCCCCCCHHH
AWLVEFEKYRATTQYQLTNAGMALSEFQFIYWWEWGHRQIGRLIGLVAVAGFAFFAWRRW
HHHHHHHHHHCCCEEEECCCCCHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQGLGWKLVGLIALGGLQGAIGWWMVSSGIGETERVSVAPYRLMTHFTLALLILAVIAW
HCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHH
LWLDLGRQQRAGAPRAAQRAAMALMGLIFVQMAAGALVAGLDAGRTYTDWPLMAGEVFPA
HHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
HYIHAELGVRSFFEGREATQFNHRLLAYGLWAGSLAAAWAFRKTDVHREFAFLAVLVSAQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVWGILTLVNAAPMGLALVHQGLGVVTTLWAVYTVWRAGGPKTVAEINPPA
HHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
>Mature Secondary Structure 
TPSAISPVAAGWIRRWLILMALMVYAIILVGGATRLTDSGLSITEWRPVSGALPPMSEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEECCCCCCCCCCCHHH
AWLVEFEKYRATTQYQLTNAGMALSEFQFIYWWEWGHRQIGRLIGLVAVAGFAFFAWRRW
HHHHHHHHHHCCCEEEECCCCCHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQGLGWKLVGLIALGGLQGAIGWWMVSSGIGETERVSVAPYRLMTHFTLALLILAVIAW
HCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHH
LWLDLGRQQRAGAPRAAQRAAMALMGLIFVQMAAGALVAGLDAGRTYTDWPLMAGEVFPA
HHHHCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
HYIHAELGVRSFFEGREATQFNHRLLAYGLWAGSLAAAWAFRKTDVHREFAFLAVLVSAQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVWGILTLVNAAPMGLALVHQGLGVVTTLWAVYTVWRAGGPKTVAEINPPA
HHHHHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA