Definition Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession NC_008358
Length 3,705,021

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The map label for this gene is ucpA [C]

Identifier: 114800228

GI number: 114800228

Start: 1727505

End: 1728293

Strand: Reverse

Name: ucpA [C]

Synonym: HNE_1684

Alternate gene names: 114800228

Gene position: 1728293-1727505 (Counterclockwise)

Preceding gene: 114799392

Following gene: 114798376

Centisome position: 46.65

GC content: 63.62

Gene sequence:

>789_bases
ATGATTACGCAGTCTACGAATGAATTTTCCGGGAAGCGTGTTGTCGTTACCGGCGGAACGCAAGGCGCGGGCTATGCCGT
GTTCGAGAAGCTTGCAGCGGCGGGGGCAACCCTTGTGACAGCTGCACGCTCTGCCCGCCCCGACACTATTCCCGAAGCGA
GCTTCGTTCGCGCCGATCTCAGCACAGCCGAGGGCGCCAACGCGCTGGCACACGCTGCCCTCGAACGCATGGGCGGCGCC
GATATTCTGGTGCATGTGCTGGGCGGATCAAAAGCGCCGGGCGGCGGCTTTGCCGCCAGCGGAGACGATGTGTGGCAGGC
GGAGCTGGACCTCAACCTGATGTCTGCCGTGCGGCTGGACCGGCTGCTGGTGCCTCAAATGATCGAGCGCGGAAAAGGCG
TGATCATTCACACCGCCTCCATCCAGCGCCGGCTTCCGCTCTACGATTCCACTACCGCTTATGCCGCGGCGAAGGCAGCG
CTGGCAGCGTACAGTAAGGCGCTGTCCAAAGAGGTCGGCCCTAAAGGCGTGCGGGTGAACGTGGTCTCTCCGGGGTGGAT
CTATACGAGCGCCGCCGAAGCGATGGTGAAGCGCATTGCCGAGAGCAGCGGCGGCAGTGAAGAAGCGGCGCGTCAATCCA
TTCTGGACGCGCTGGGCGGCATCCCCATCGGACGCCCCGCCCTTCCCGAAGAAGTGGCAGACCTGATCGCGTTTCTCGTC
TCTGACCGGGCCGGGTCCATTCACGGCGCTGAGTATGTGATTGATGGCGGAACCATACCGACGCTCTGA

Upstream 100 bases:

>100_bases
TGACGGCAAATGTGGCCGGTGCGTTTCCCGGCAGCCCCGTCATGCTGACATTCCGCTTTCGCCTCAGCGAGGACAAGATC
GCACATCTGGAGATTGCCCC

Downstream 100 bases:

>100_bases
GGGCGGCTCATGAACGAAGGCGCCAACACTTACCTTTACACAACGTACACATGAAAAATCCCGGTTTTCCGTGCCTTTGC
CCGGAAAACGCCTTTTCACG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: ORF5 [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MITQSTNEFSGKRVVVTGGTQGAGYAVFEKLAAAGATLVTAARSARPDTIPEASFVRADLSTAEGANALAHAALERMGGA
DILVHVLGGSKAPGGGFAASGDDVWQAELDLNLMSAVRLDRLLVPQMIERGKGVIIHTASIQRRLPLYDSTTAYAAAKAA
LAAYSKALSKEVGPKGVRVNVVSPGWIYTSAAEAMVKRIAESSGGSEEAARQSILDALGGIPIGRPALPEEVADLIAFLV
SDRAGSIHGAEYVIDGGTIPTL

Sequences:

>Translated_262_residues
MITQSTNEFSGKRVVVTGGTQGAGYAVFEKLAAAGATLVTAARSARPDTIPEASFVRADLSTAEGANALAHAALERMGGA
DILVHVLGGSKAPGGGFAASGDDVWQAELDLNLMSAVRLDRLLVPQMIERGKGVIIHTASIQRRLPLYDSTTAYAAAKAA
LAAYSKALSKEVGPKGVRVNVVSPGWIYTSAAEAMVKRIAESSGGSEEAARQSILDALGGIPIGRPALPEEVADLIAFLV
SDRAGSIHGAEYVIDGGTIPTL
>Mature_262_residues
MITQSTNEFSGKRVVVTGGTQGAGYAVFEKLAAAGATLVTAARSARPDTIPEASFVRADLSTAEGANALAHAALERMGGA
DILVHVLGGSKAPGGGFAASGDDVWQAELDLNLMSAVRLDRLLVPQMIERGKGVIIHTASIQRRLPLYDSTTAYAAAKAA
LAAYSKALSKEVGPKGVRVNVVSPGWIYTSAAEAMVKRIAESSGGSEEAARQSILDALGGIPIGRPALPEEVADLIAFLV
SDRAGSIHGAEYVIDGGTIPTL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=265, Percent_Identity=29.4339622641509, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7705925, Length=255, Percent_Identity=28.2352941176471, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=27.8884462151394, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI126723750, Length=263, Percent_Identity=26.9961977186312, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI59889578, Length=248, Percent_Identity=27.0161290322581, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI33667109, Length=184, Percent_Identity=32.0652173913043, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI66933014, Length=199, Percent_Identity=27.1356783919598, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI20149619, Length=192, Percent_Identity=32.2916666666667, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI15277342, Length=276, Percent_Identity=27.536231884058, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=26.5873015873016, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=30.4182509505703, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787335, Length=262, Percent_Identity=30.5343511450382, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786812, Length=265, Percent_Identity=32.0754716981132, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI87082160, Length=274, Percent_Identity=30.2919708029197, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1788459, Length=208, Percent_Identity=31.25, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787905, Length=274, Percent_Identity=28.1021897810219, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=29.3172690763052, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789378, Length=210, Percent_Identity=30, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=26.1363636363636, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790717, Length=271, Percent_Identity=23.9852398523985, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI2367175, Length=125, Percent_Identity=35.2, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=271, Percent_Identity=31.7343173431734, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=278, Percent_Identity=33.4532374100719, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=269, Percent_Identity=29.368029739777, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=29.6296296296296, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=31.5018315018315, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=30.4832713754647, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=28.7822878228782, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=30, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=200, Percent_Identity=31.5, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30.7407407407407, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=29.9625468164794, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=199, Percent_Identity=29.1457286432161, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565030, Length=276, Percent_Identity=29.3478260869565, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17544670, Length=271, Percent_Identity=29.8892988929889, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=29.8892988929889, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=29.6296296296296, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=28.6821705426357, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=31.8518518518519, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=28.5185185185185, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=273, Percent_Identity=30.7692307692308, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=258, Percent_Identity=27.5193798449612, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=274, Percent_Identity=28.1021897810219, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=27.4131274131274, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17560220, Length=275, Percent_Identity=29.0909090909091, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21355319, Length=266, Percent_Identity=30.0751879699248, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=30.8880308880309, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=29.3436293436293, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=29.277566539924, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24639444, Length=263, Percent_Identity=28.1368821292776, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=26.3358778625954, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=25.968992248062, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358495, Length=196, Percent_Identity=27.5510204081633, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=31.9371727748691, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=31.9371727748691, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644337, Length=261, Percent_Identity=29.8850574712644, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=32.1052631578947, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=32.1052631578947, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26923; Mature: 26923

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MITQSTNEFSGKRVVVTGGTQGAGYAVFEKLAAAGATLVTAARSARPDTIPEASFVRADL
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHC
STAEGANALAHAALERMGGADILVHVLGGSKAPGGGFAASGDDVWQAELDLNLMSAVRLD
CCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
RLLVPQMIERGKGVIIHTASIQRRLPLYDSTTAYAAAKAALAAYSKALSKEVGPKGVRVN
HHHHHHHHHCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VVSPGWIYTSAAEAMVKRIAESSGGSEEAARQSILDALGGIPIGRPALPEEVADLIAFLV
EECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SDRAGSIHGAEYVIDGGTIPTL
HCCCCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MITQSTNEFSGKRVVVTGGTQGAGYAVFEKLAAAGATLVTAARSARPDTIPEASFVRADL
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHC
STAEGANALAHAALERMGGADILVHVLGGSKAPGGGFAASGDDVWQAELDLNLMSAVRLD
CCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
RLLVPQMIERGKGVIIHTASIQRRLPLYDSTTAYAAAKAALAAYSKALSKEVGPKGVRVN
HHHHHHHHHCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VVSPGWIYTSAAEAMVKRIAESSGGSEEAARQSILDALGGIPIGRPALPEEVADLIAFLV
EECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SDRAGSIHGAEYVIDGGTIPTL
HCCCCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1508151 [H]