Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 114800173

GI number: 114800173

Start: 1303992

End: 1305959

Strand: Reverse

Name: luxQ [H]

Synonym: HNE_1275

Alternate gene names: 114800173

Gene position: 1305959-1303992 (Counterclockwise)

Preceding gene: 114798346

Following gene: 114799419

Centisome position: 35.25

GC content: 61.13

Gene sequence:

>1968_bases
ATGGATGCACGTCTCTTTGACCTGCTGCCTGTCGTCGTATGCGAAATTGCGCCGGTGCGCGCGCCTGACGGCACGATCAT
TGACCTGGAATGGATTGATGCAAACCGCCTGATGAACGAATCGATCCTGCCGAATGGCGGCAGTATCGTCGGCATGCGGG
TTTTCGAGTTTGACCCCGCCTATCGCGACTCCGAGATGACAAAGAACGTCATCCAGGTCATCGAGACCGGAGAGCCGATC
ACCTACATCACCGGCCTCGGCCGCGCCGCGAAGATGCTGGGGAAGGTGATGAAAACCGTCATCACGCCCACAGAATTTGG
CGCGCTGGCCTGCTCGCATGAGGTCACCGAACTGGCCGAGGAGCGCGACGCCGCCCTCAAACGCTTCCAGCTTGCCCGCG
CCGCCTGCGACCACGCCATCCACGGCATTGTCGTCACCGACCGCGAAAGCCGGATACATTATGTCAATCATGCCATCTGT
GAACTGATCGGATATTCCGAGGAAGAGCTGCTCGGCAAGGATGTCGGCATCCTGTTTGGCGTCAAGGCTTTCCAGCCCCA
GAAGGCGCTTGGCAACCAGGTCGTCTCCGAGATTGAAAGCGGCAAGCTCATCCGCCACATCTCCGACGCGGAAGCCTACA
CCCGCGACGGCGTCAAAATCCGCGTCCAGGCGTCCACCTCAAGCACCCATTGGGGCGAGGACGACGATATGGTGTTCATC
ACCTACATCCGCGATGTGCGCGAGGAACGCCGCAAGGCGCATGAACTCCGCGACGCGCTCAACCGCGCCGAGCAGGCCAC
GCGCCTGAAATCGGAATTTCTCGCCAATATGAGCCATGAGATCCGCACACCCCTCAACGGCGTGCTCGGCATGGCGCAGG
TACTTGCCCATGGAAAATTGACAGAAGCCCAGGCCGAACAGGTCGGCGTGATCCTCGATTCGGGCAACACGCTCATGGTC
CTGCTCAACGATATTCTCGACCTTTCCAAGATCGAAGCCGGCCGTATGGACCTCTCGCCTGTGCCAGGCGACCTGCGCCA
CAAGCTCAGCGGCCTGTTCAAGCTGCACGAGGCCGCCGCCAACGAGAAGGGCATCGGCATCCGCCTTTTTGTGGACCCCA
GCGTGCCATCGCGCCTGCTGTTTGATCCTGTTCGCGTGCGCCAGTGCGTCAGCAACCTCCTCTCCAACGCCATCAAGTTC
ACCAGCCAGGGTGAAGTGATGCTCGTGGTCACCTCCGAGCCGGTTCAGAGCGGCGCCCACCGCGTCATCATGCACGTGTC
CGACACCGGCGTCGGCATCGCCGCAGACAAAGTCGACCGCATCTTCGAAAGCTTTGCGCAGGAAGATGGCTCCACCACCC
GCAAGTTCGGTGGCACTGGGCTGGGTCTATCGATCACGCGCCGCCTCGCCCGGATGATGGGCGGCGACGTTACTGCTGTC
AGCCAGGTTGGCAAGGGATCGATCTTTACACTGAAATTCATCGCCCATTCCTCGGCCGCAGGGGCCGGCGACACCAAGAA
CATGATCCACATGCCGGTCCGCACGGCGCGCACCGGCCTCACCGGTTGCCGCGCGCTTGTGGTCGACGACAATGGCATCA
ACCGCCGCGTCGCCCGCTCTTTCCTCGAATACTACGGCATCATCATCCGCGAAGCCTGCGACGGCAATGAAGCGCTCGAA
ATCATGGCGAAGGAAACCTTCGATTTCGTGCTGATGGACATCCACATGCCCGGCCTCGACGGCGAAGAAGCCTTCAAGCG
CCTGCGCACGTCGGGCAGTCTCAACCGCCTGGTTCCGGTAATCGCCCTGACAGCCGACTCCATGCACGGGGACCGCGAGA
AATTCCTCGGTAAGGGTTTTGACGGCTATGTCTCCAAGCCGATTGACGAGCGCACGATGATCACCGTCATCAGCCAGGTC
TTGAGTGTCCCCGCTGAGGAAACAGAAGCCTTGCTCGCGGCGGGCTGA

Upstream 100 bases:

>100_bases
GCCCGCCGGAAGTCCCGAACCTTGTATTATCAACACTACATTAAGTATGTTCGCTGAAGATTCCGGCAAAGAAACTAGAT
GGCTTTCAAGGAATCACTCA

Downstream 100 bases:

>100_bases
CGCGAGGTGACCCTGTCTCCGTCGCGGCGTTCCGTAGACGGTGCTTGCAAATGCCGCCTATACTGCGCGCTGGACAGTGA
TTGCCCGCCGCATCGTGAAG

Product: sensory box sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MDARLFDLLPVVVCEIAPVRAPDGTIIDLEWIDANRLMNESILPNGGSIVGMRVFEFDPAYRDSEMTKNVIQVIETGEPI
TYITGLGRAAKMLGKVMKTVITPTEFGALACSHEVTELAEERDAALKRFQLARAACDHAIHGIVVTDRESRIHYVNHAIC
ELIGYSEEELLGKDVGILFGVKAFQPQKALGNQVVSEIESGKLIRHISDAEAYTRDGVKIRVQASTSSTHWGEDDDMVFI
TYIRDVREERRKAHELRDALNRAEQATRLKSEFLANMSHEIRTPLNGVLGMAQVLAHGKLTEAQAEQVGVILDSGNTLMV
LLNDILDLSKIEAGRMDLSPVPGDLRHKLSGLFKLHEAAANEKGIGIRLFVDPSVPSRLLFDPVRVRQCVSNLLSNAIKF
TSQGEVMLVVTSEPVQSGAHRVIMHVSDTGVGIAADKVDRIFESFAQEDGSTTRKFGGTGLGLSITRRLARMMGGDVTAV
SQVGKGSIFTLKFIAHSSAAGAGDTKNMIHMPVRTARTGLTGCRALVVDDNGINRRVARSFLEYYGIIIREACDGNEALE
IMAKETFDFVLMDIHMPGLDGEEAFKRLRTSGSLNRLVPVIALTADSMHGDREKFLGKGFDGYVSKPIDERTMITVISQV
LSVPAEETEALLAAG

Sequences:

>Translated_655_residues
MDARLFDLLPVVVCEIAPVRAPDGTIIDLEWIDANRLMNESILPNGGSIVGMRVFEFDPAYRDSEMTKNVIQVIETGEPI
TYITGLGRAAKMLGKVMKTVITPTEFGALACSHEVTELAEERDAALKRFQLARAACDHAIHGIVVTDRESRIHYVNHAIC
ELIGYSEEELLGKDVGILFGVKAFQPQKALGNQVVSEIESGKLIRHISDAEAYTRDGVKIRVQASTSSTHWGEDDDMVFI
TYIRDVREERRKAHELRDALNRAEQATRLKSEFLANMSHEIRTPLNGVLGMAQVLAHGKLTEAQAEQVGVILDSGNTLMV
LLNDILDLSKIEAGRMDLSPVPGDLRHKLSGLFKLHEAAANEKGIGIRLFVDPSVPSRLLFDPVRVRQCVSNLLSNAIKF
TSQGEVMLVVTSEPVQSGAHRVIMHVSDTGVGIAADKVDRIFESFAQEDGSTTRKFGGTGLGLSITRRLARMMGGDVTAV
SQVGKGSIFTLKFIAHSSAAGAGDTKNMIHMPVRTARTGLTGCRALVVDDNGINRRVARSFLEYYGIIIREACDGNEALE
IMAKETFDFVLMDIHMPGLDGEEAFKRLRTSGSLNRLVPVIALTADSMHGDREKFLGKGFDGYVSKPIDERTMITVISQV
LSVPAEETEALLAAG
>Mature_655_residues
MDARLFDLLPVVVCEIAPVRAPDGTIIDLEWIDANRLMNESILPNGGSIVGMRVFEFDPAYRDSEMTKNVIQVIETGEPI
TYITGLGRAAKMLGKVMKTVITPTEFGALACSHEVTELAEERDAALKRFQLARAACDHAIHGIVVTDRESRIHYVNHAIC
ELIGYSEEELLGKDVGILFGVKAFQPQKALGNQVVSEIESGKLIRHISDAEAYTRDGVKIRVQASTSSTHWGEDDDMVFI
TYIRDVREERRKAHELRDALNRAEQATRLKSEFLANMSHEIRTPLNGVLGMAQVLAHGKLTEAQAEQVGVILDSGNTLMV
LLNDILDLSKIEAGRMDLSPVPGDLRHKLSGLFKLHEAAANEKGIGIRLFVDPSVPSRLLFDPVRVRQCVSNLLSNAIKF
TSQGEVMLVVTSEPVQSGAHRVIMHVSDTGVGIAADKVDRIFESFAQEDGSTTRKFGGTGLGLSITRRLARMMGGDVTAV
SQVGKGSIFTLKFIAHSSAAGAGDTKNMIHMPVRTARTGLTGCRALVVDDNGINRRVARSFLEYYGIIIREACDGNEALE
IMAKETFDFVLMDIHMPGLDGEEAFKRLRTSGSLNRLVPVIALTADSMHGDREKFLGKGFDGYVSKPIDERTMITVISQV
LSVPAEETEALLAAG

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=405, Percent_Identity=35.0617283950617, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789149, Length=235, Percent_Identity=41.7021276595745, Blast_Score=199, Evalue=6e-52,
Organism=Escherichia coli, GI87081816, Length=403, Percent_Identity=33.7468982630273, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1788713, Length=427, Percent_Identity=30.6791569086651, Blast_Score=192, Evalue=7e-50,
Organism=Escherichia coli, GI145693157, Length=323, Percent_Identity=33.1269349845201, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1790436, Length=256, Percent_Identity=32.421875, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786783, Length=237, Percent_Identity=27.4261603375527, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1788549, Length=400, Percent_Identity=23, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=25.6521739130435, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=240, Percent_Identity=28.75, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786912, Length=246, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=26.3392857142857, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790861, Length=251, Percent_Identity=27.0916334661355, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788279, Length=246, Percent_Identity=25.2032520325203, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=32.5, Blast_Score=62, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=125, Percent_Identity=34.4, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=107, Percent_Identity=33.6448598130841, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71605; Mature: 71605

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARLFDLLPVVVCEIAPVRAPDGTIIDLEWIDANRLMNESILPNGGSIVGMRVFEFDPA
CCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCEEEEEEEECCCC
YRDSEMTKNVIQVIETGEPITYITGLGRAAKMLGKVMKTVITPTEFGALACSHEVTELAE
CCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ERDAALKRFQLARAACDHAIHGIVVTDRESRIHYVNHAICELIGYSEEELLGKDVGILFG
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHEE
VKAFQPQKALGNQVVSEIESGKLIRHISDAEAYTRDGVKIRVQASTSSTHWGEDDDMVFI
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEH
TYIRDVREERRKAHELRDALNRAEQATRLKSEFLANMSHEIRTPLNGVLGMAQVLAHGKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
TEAQAEQVGVILDSGNTLMVLLNDILDLSKIEAGRMDLSPVPGDLRHKLSGLFKLHEAAA
CHHHHHHEEEEEECCCEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
NEKGIGIRLFVDPSVPSRLLFDPVRVRQCVSNLLSNAIKFTSQGEVMLVVTSEPVQSGAH
CCCCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCHHCCCE
RVIMHVSDTGVGIAADKVDRIFESFAQEDGSTTRKFGGTGLGLSITRRLARMMGGDVTAV
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCHHH
SQVGKGSIFTLKFIAHSSAAGAGDTKNMIHMPVRTARTGLTGCRALVVDDNGINRRVARS
HHCCCCCEEEEEEEECCCCCCCCCCCCEEECCHHHHHCCCCCCEEEEECCCCCCHHHHHH
FLEYYGIIIREACDGNEALEIMAKETFDFVLMDIHMPGLDGEEAFKRLRTSGSLNRLVPV
HHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHE
IALTADSMHGDREKFLGKGFDGYVSKPIDERTMITVISQVLSVPAEETEALLAAG
EEEECCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MDARLFDLLPVVVCEIAPVRAPDGTIIDLEWIDANRLMNESILPNGGSIVGMRVFEFDPA
CCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCCCEEEEEEEECCCC
YRDSEMTKNVIQVIETGEPITYITGLGRAAKMLGKVMKTVITPTEFGALACSHEVTELAE
CCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ERDAALKRFQLARAACDHAIHGIVVTDRESRIHYVNHAICELIGYSEEELLGKDVGILFG
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHHEE
VKAFQPQKALGNQVVSEIESGKLIRHISDAEAYTRDGVKIRVQASTSSTHWGEDDDMVFI
CCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEH
TYIRDVREERRKAHELRDALNRAEQATRLKSEFLANMSHEIRTPLNGVLGMAQVLAHGKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
TEAQAEQVGVILDSGNTLMVLLNDILDLSKIEAGRMDLSPVPGDLRHKLSGLFKLHEAAA
CHHHHHHEEEEEECCCEEEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
NEKGIGIRLFVDPSVPSRLLFDPVRVRQCVSNLLSNAIKFTSQGEVMLVVTSEPVQSGAH
CCCCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCHHCCCE
RVIMHVSDTGVGIAADKVDRIFESFAQEDGSTTRKFGGTGLGLSITRRLARMMGGDVTAV
EEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCHHH
SQVGKGSIFTLKFIAHSSAAGAGDTKNMIHMPVRTARTGLTGCRALVVDDNGINRRVARS
HHCCCCCEEEEEEEECCCCCCCCCCCCEEECCHHHHHCCCCCCEEEEECCCCCCHHHHHH
FLEYYGIIIREACDGNEALEIMAKETFDFVLMDIHMPGLDGEEAFKRLRTSGSLNRLVPV
HHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHE
IALTADSMHGDREKFLGKGFDGYVSKPIDERTMITVISQVLSVPAEETEALLAAG
EEEECCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA