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The map label for this gene is ychK [C]

Identifier: 114798346

GI number: 114798346

Start: 1306062

End: 1307840

Strand: Reverse

Name: ychK [C]

Synonym: HNE_1276

Alternate gene names: 114798346

Gene position: 1307840-1306062 (Counterclockwise)

Preceding gene: 114797848

Following gene: 114800173

Centisome position: 35.3

GC content: 66.67

Gene sequence:

>1779_bases
ATGTTTGGCCTGCTGCGTAATAATTTCACGCCCGATCTGAAGACGATCCCTCTCCTGAAGGACGTGTCCCAGCGGGCTAT
GCGCTCTGCCGGCAAGGAGGCGCGCTGGTTTGCGCTGCCCGCCGGCCAGCCGCTGTTCCTTGCGGGCGAGCCTGCCGATT
GCATCTATTTCGTCCTCTCCGGCGCCCTCGGCGCATTCGGCGCCAAGGGTGAATTCGTCGGCAACATCCGCCCTGGCGAA
CCGGTTGGCGAGATGGCGCTTTTCCTGGGCGGAAAAGACACCAATGGCGACGGCGCCGCCGAAGATGCGCCTCATTCCGG
CTCCGTTTACGCGCTGCGCGATTCCGAAGTCATCGCCCTCTCCCGCGCCGGCTGGAAGCTGCTGGTGAAGTCCGAGCCCG
AACTGCTGGAAGGGATGATCCGCATCATCCTTCGCCGCCTCGGCCGGGGCGACCAGCGCAATGCCGAGGCCCCGCCCAAG
GTCTACACCCTCGTCTCCACCTCTCCGACCATCGACCTGACCCTGCGCGCCCGCGCGCTGAAGTCCGCCCTCGCCCGCTT
CGGCAAGCGCGCCGTCATCGTCAGCGATCTGGAGGGCGACGACAAACCCGCTGCCTTCTTCGACGCGCTGGAAACAGATA
ATGATGTCGTCATCCTGACCGCGCCCATCGGCGCGACGCCCTGGTTCCGCCTCGCCACGCGCCAGGCGGACCGGATCTGG
GTGCTCGCCCGGTCCGATGCGCGCCCGTCTACGCCGCTGATGCCGGAAGAAACCTCGCCGGCCCAGCGCCTGAAGCTGAT
CGATGTGATCCTGATCCATCCCGGCGCCGAACGGCGCGCCTCACGGCCGCAGGAGTGGACGCAGGCGGCCGGCGCCCGGC
GCCTCTTTCACTGGCAGGGCGACAATGGCGAAGACGCGATGCGTCTGGCCCGCGTGATGACCGGCCGCTCGGTGGGCCTC
GTCCTCTCGGGCGGCGGCGCCCGCGCCTACAGCCATATCGGCGCCATCCGCGCCATCCGCGATCTTGGCATCCCGATCGA
CTTTGCCGGCGGCGCCTCAATGGGCGCAGTCGTCGCCGCCTGCGCCGCCATCGGCTGGGACGATAACGAGATCGACTGGC
GCATCCGCAAGGCGTTCGTGGAGTCCAATCCGCTGGGCGATTACAACATTCCCGTCGTCGGCATGGTCAAAGGCAAGCGC
GTCAACCAGCGCCTGCAGGAGCATTTCGGCGACGTCGACATCGGCGACCTGCAAATCCCCTTCTTCGCCCTATCGACCAA
CCTCACCAGCGGCCAGGCAAAGCTGCACCGTTCCGGCAGCCTGCGCGACGCCCTGCGCGCCACCATCTCCCTGCCCGGTA
TTCTGCCGCCTTTCGTGGACGGCGACGACATCCTCGTTGATGGCGCCGTGCTGGATAACTTCCCCGTAGAGCCGATGCGC
GCCCTGCATCAGGGCGTCGTGATCGGCTCAGACGTCTCTGCCCTCCCCGATGGCCTCAACCGGGAAGAATTTGCCAAGCC
CATGAGCTTCTGGAAATGGGTGCTCACGCACGGCTTTTCCTCACCCCCGCCCATCGCCGGCCTGCTGATGCGCGCCGCCA
CCATCCGCGACGACCGCCTCACCCCGCGCGACATGGCCGACATCCTGATCCTGCCCGAGCTGCCCAGCATCGAATTGCGC
GACTGGAAAGCGTATGACGTGTCCGTGGAAGCTGGCTACACGGCCGCCATGGAAGCCCTGAAGGATCACGAAATCCGGGA
CCTCTGCTGCCCGGCCTGA

Upstream 100 bases:

>100_bases
GCAGGATTAACGGTCTGCCGCTGCGCTGTCACCCGTTGGTAAACTCTTTTGTGTTACAGGTCTTGAAGCTGCCCCTTTCA
GGATTCAGGTAACGCGCAAC

Downstream 100 bases:

>100_bases
CGGCCCGCCGGAAGTCCCGAACCTTGTATTATCAACACTACATTAAGTATGTTCGCTGAAGATTCCGGCAAAGAAACTAG
ATGGCTTTCAAGGAATCACT

Product: cyclic nucleotide-binding/patatin-like phospholipase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MFGLLRNNFTPDLKTIPLLKDVSQRAMRSAGKEARWFALPAGQPLFLAGEPADCIYFVLSGALGAFGAKGEFVGNIRPGE
PVGEMALFLGGKDTNGDGAAEDAPHSGSVYALRDSEVIALSRAGWKLLVKSEPELLEGMIRIILRRLGRGDQRNAEAPPK
VYTLVSTSPTIDLTLRARALKSALARFGKRAVIVSDLEGDDKPAAFFDALETDNDVVILTAPIGATPWFRLATRQADRIW
VLARSDARPSTPLMPEETSPAQRLKLIDVILIHPGAERRASRPQEWTQAAGARRLFHWQGDNGEDAMRLARVMTGRSVGL
VLSGGGARAYSHIGAIRAIRDLGIPIDFAGGASMGAVVAACAAIGWDDNEIDWRIRKAFVESNPLGDYNIPVVGMVKGKR
VNQRLQEHFGDVDIGDLQIPFFALSTNLTSGQAKLHRSGSLRDALRATISLPGILPPFVDGDDILVDGAVLDNFPVEPMR
ALHQGVVIGSDVSALPDGLNREEFAKPMSFWKWVLTHGFSSPPPIAGLLMRAATIRDDRLTPRDMADILILPELPSIELR
DWKAYDVSVEAGYTAAMEALKDHEIRDLCCPA

Sequences:

>Translated_592_residues
MFGLLRNNFTPDLKTIPLLKDVSQRAMRSAGKEARWFALPAGQPLFLAGEPADCIYFVLSGALGAFGAKGEFVGNIRPGE
PVGEMALFLGGKDTNGDGAAEDAPHSGSVYALRDSEVIALSRAGWKLLVKSEPELLEGMIRIILRRLGRGDQRNAEAPPK
VYTLVSTSPTIDLTLRARALKSALARFGKRAVIVSDLEGDDKPAAFFDALETDNDVVILTAPIGATPWFRLATRQADRIW
VLARSDARPSTPLMPEETSPAQRLKLIDVILIHPGAERRASRPQEWTQAAGARRLFHWQGDNGEDAMRLARVMTGRSVGL
VLSGGGARAYSHIGAIRAIRDLGIPIDFAGGASMGAVVAACAAIGWDDNEIDWRIRKAFVESNPLGDYNIPVVGMVKGKR
VNQRLQEHFGDVDIGDLQIPFFALSTNLTSGQAKLHRSGSLRDALRATISLPGILPPFVDGDDILVDGAVLDNFPVEPMR
ALHQGVVIGSDVSALPDGLNREEFAKPMSFWKWVLTHGFSSPPPIAGLLMRAATIRDDRLTPRDMADILILPELPSIELR
DWKAYDVSVEAGYTAAMEALKDHEIRDLCCPA
>Mature_592_residues
MFGLLRNNFTPDLKTIPLLKDVSQRAMRSAGKEARWFALPAGQPLFLAGEPADCIYFVLSGALGAFGAKGEFVGNIRPGE
PVGEMALFLGGKDTNGDGAAEDAPHSGSVYALRDSEVIALSRAGWKLLVKSEPELLEGMIRIILRRLGRGDQRNAEAPPK
VYTLVSTSPTIDLTLRARALKSALARFGKRAVIVSDLEGDDKPAAFFDALETDNDVVILTAPIGATPWFRLATRQADRIW
VLARSDARPSTPLMPEETSPAQRLKLIDVILIHPGAERRASRPQEWTQAAGARRLFHWQGDNGEDAMRLARVMTGRSVGL
VLSGGGARAYSHIGAIRAIRDLGIPIDFAGGASMGAVVAACAAIGWDDNEIDWRIRKAFVESNPLGDYNIPVVGMVKGKR
VNQRLQEHFGDVDIGDLQIPFFALSTNLTSGQAKLHRSGSLRDALRATISLPGILPPFVDGDDILVDGAVLDNFPVEPMR
ALHQGVVIGSDVSALPDGLNREEFAKPMSFWKWVLTHGFSSPPPIAGLLMRAATIRDDRLTPRDMADILILPELPSIELR
DWKAYDVSVEAGYTAAMEALKDHEIRDLCCPA

Specific function: Unknown

COG id: COG1752

COG function: function code R; Predicted esterase of the alpha-beta hydrolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 patatin domain [H]

Homologues:

Organism=Homo sapiens, GI260656039, Length=550, Percent_Identity=26.3636363636364, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI260656041, Length=551, Percent_Identity=26.3157894736842, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI116256487, Length=551, Percent_Identity=26.3157894736842, Blast_Score=176, Evalue=6e-44,
Organism=Homo sapiens, GI260656043, Length=550, Percent_Identity=26.3636363636364, Blast_Score=176, Evalue=7e-44,
Organism=Homo sapiens, GI260656037, Length=551, Percent_Identity=26.3157894736842, Blast_Score=176, Evalue=8e-44,
Organism=Homo sapiens, GI148727335, Length=554, Percent_Identity=27.9783393501805, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI148727290, Length=554, Percent_Identity=27.9783393501805, Blast_Score=166, Evalue=7e-41,
Organism=Escherichia coli, GI226510936, Length=280, Percent_Identity=28.5714285714286, Blast_Score=109, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI193204778, Length=543, Percent_Identity=24.4935543278085, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71997299, Length=641, Percent_Identity=24.0249609984399, Blast_Score=122, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71997289, Length=641, Percent_Identity=24.0249609984399, Blast_Score=121, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6323581, Length=233, Percent_Identity=36.0515021459227, Blast_Score=137, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281376913, Length=562, Percent_Identity=26.6903914590747, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI28571388, Length=562, Percent_Identity=26.6903914590747, Blast_Score=160, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016035
- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001423
- InterPro:   IPR002641
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00027 cNMP_binding; PF01734 Patatin [H]

EC number: NA

Molecular weight: Translated: 64222; Mature: 64222

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLLRNNFTPDLKTIPLLKDVSQRAMRSAGKEARWFALPAGQPLFLAGEPADCIYFVLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCHHHHHHHHH
GALGAFGAKGEFVGNIRPGEPVGEMALFLGGKDTNGDGAAEDAPHSGSVYALRDSEVIAL
HHHHCCCCCCCEEECCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCEEEE
SRAGWKLLVKSEPELLEGMIRIILRRLGRGDQRNAEAPPKVYTLVSTSPTIDLTLRARAL
ECCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHH
KSALARFGKRAVIVSDLEGDDKPAAFFDALETDNDVVILTAPIGATPWFRLATRQADRIW
HHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCEEE
VLARSDARPSTPLMPEETSPAQRLKLIDVILIHPGAERRASRPQEWTQAAGARRLFHWQG
EEEECCCCCCCCCCCCCCCHHHHHEEEEEEEECCCHHHHCCCCHHHHHHHCCCEEEEECC
DNGEDAMRLARVMTGRSVGLVLSGGGARAYSHIGAIRAIRDLGIPIDFAGGASMGAVVAA
CCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHH
CAAIGWDDNEIDWRIRKAFVESNPLGDYNIPVVGMVKGKRVNQRLQEHFGDVDIGDLQIP
HHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEE
FFALSTNLTSGQAKLHRSGSLRDALRATISLPGILPPFVDGDDILVDGAVLDNFPVEPMR
EEEEECCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECEEECCCCCHHHH
ALHQGVVIGSDVSALPDGLNREEFAKPMSFWKWVLTHGFSSPPPIAGLLMRAATIRDDRL
HHHCCEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCC
TPRDMADILILPELPSIELRDWKAYDVSVEAGYTAAMEALKDHEIRDLCCPA
CHHCCCCEEEECCCCCCEECCCEEEEEEECCCHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MFGLLRNNFTPDLKTIPLLKDVSQRAMRSAGKEARWFALPAGQPLFLAGEPADCIYFVLS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCHHHHHHHHH
GALGAFGAKGEFVGNIRPGEPVGEMALFLGGKDTNGDGAAEDAPHSGSVYALRDSEVIAL
HHHHCCCCCCCEEECCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCEEEE
SRAGWKLLVKSEPELLEGMIRIILRRLGRGDQRNAEAPPKVYTLVSTSPTIDLTLRARAL
ECCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEHHHHH
KSALARFGKRAVIVSDLEGDDKPAAFFDALETDNDVVILTAPIGATPWFRLATRQADRIW
HHHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCCCCEEE
VLARSDARPSTPLMPEETSPAQRLKLIDVILIHPGAERRASRPQEWTQAAGARRLFHWQG
EEEECCCCCCCCCCCCCCCHHHHHEEEEEEEECCCHHHHCCCCHHHHHHHCCCEEEEECC
DNGEDAMRLARVMTGRSVGLVLSGGGARAYSHIGAIRAIRDLGIPIDFAGGASMGAVVAA
CCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHH
CAAIGWDDNEIDWRIRKAFVESNPLGDYNIPVVGMVKGKRVNQRLQEHFGDVDIGDLQIP
HHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHCCCCCCCCEEEE
FFALSTNLTSGQAKLHRSGSLRDALRATISLPGILPPFVDGDDILVDGAVLDNFPVEPMR
EEEEECCCCCCHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEECEEECCCCCHHHH
ALHQGVVIGSDVSALPDGLNREEFAKPMSFWKWVLTHGFSSPPPIAGLLMRAATIRDDRL
HHHCCEEECCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCC
TPRDMADILILPELPSIELRDWKAYDVSVEAGYTAAMEALKDHEIRDLCCPA
CHHCCCCEEEECCCCCCEECCCEEEEEEECCCHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]