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The map label for this gene is cobT [H]

Identifier: 114800060

GI number: 114800060

Start: 2169615

End: 2170610

Strand: Reverse

Name: cobT [H]

Synonym: HNE_2095

Alternate gene names: 114800060

Gene position: 2170610-2169615 (Counterclockwise)

Preceding gene: 114800553

Following gene: 114799055

Centisome position: 58.59

GC content: 65.86

Gene sequence:

>996_bases
TTGAGCGAACCCAATCGGAACAAGTCCCCCCTGGATGATGTCCGCGACCTGATCCTGAAGCCGGTCGAGACCGATCCGGA
AGCTGGGCGCAAAGTCCACGAGGCGCTTCTCGGCATGGGCCGGGAGGGGGATTTCGGCCGTCTGGGCGAGGCCGCCGAGT
GGTTGGCCACCTGGCAGCGCCGGTTTCCGCCCCGTGTGGAAAAGCCGACGCTGGCGATCTTTGCGGGCTCGCACGGCCTT
GTCGATTCCGGGGTTTCTCTGTCTTCGAATGAAGATACCCGCGCGCATATCGAGGCGCTGAAGTCTGGCCGGGCACCCTT
GTCAGCCATCGCGACCCAGGTCGGCGCGAATGTCCGGGTCTTCGAACTCGCGCTCGACAAGCCTACGCCCAGCATCTCCG
AGACGGCGGCGATGTCGGAACGCGAATGCGCGGCGACGATCGCGTTTGGTTTCGAGGCCGTCGAGGACAATCCGGACCTG
TTGGCCCTTGCGGTGTCGGGGGCGGGGGTTGGCACGGTGGCTGCGGCCGTGGCCTGCGCGCTTTACGGCGGATCGCCGGA
ATACTGGGTGCGGCCGAGCGCGCATACGCCGGCCGAACTCTCCCGCAAGCGGGTGGAGCTCGTCAGCGCTGCCCTGAAAG
TTCACCGCGGGCATTTGTCCGATCCGCTGGAATCCCTCCGGTGCCTTGGAGGGCGCGAAATAGCCGCCTGCGTTGGCGCA
ATTATCGCGGCGCGTCATCAGGGCATCCCGGTGCTTCTGGACGGGTTTGCGACCACGATTGCAGCGGGCATTGTCCACGC
CGTCTCGCCTCAGGCGGTCAGCCATTGCCTTGCCTCTCACATCACCCAGCGCCCGGCCCATGAAGCCGCTCTGGAACGCA
TCGGCCTCAAGCCGCTCGTTCAGCTGGAGTTCCAGACGGGCAGCGGTCTTGGCTCGGCGACGGCGGTGGGGCTTCTCAAA
ACGGCCTGCGCACCGTTTATTGCCAAGCCAGCTTAG

Upstream 100 bases:

>100_bases
GTTCTACAGGAGAGGATGAAATAAATCCTTGCCGGACGGCGTGTACCTTATCTGCCATAATTAAGATTGCCGGCAATTTC
GGTAACAGGAGATTACTGCC

Downstream 100 bases:

>100_bases
GGGTGACGCAACGAAAACTGCGGCATTCTTTACGTTTACGTGCGCGTCACCTTGTCAGCGAATAGGAATGGCTGACATAC
AGAAATGAAGTGCCGGGACC

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 331; Mature: 330

Protein sequence:

>331_residues
MSEPNRNKSPLDDVRDLILKPVETDPEAGRKVHEALLGMGREGDFGRLGEAAEWLATWQRRFPPRVEKPTLAIFAGSHGL
VDSGVSLSSNEDTRAHIEALKSGRAPLSAIATQVGANVRVFELALDKPTPSISETAAMSERECAATIAFGFEAVEDNPDL
LALAVSGAGVGTVAAAVACALYGGSPEYWVRPSAHTPAELSRKRVELVSAALKVHRGHLSDPLESLRCLGGREIAACVGA
IIAARHQGIPVLLDGFATTIAAGIVHAVSPQAVSHCLASHITQRPAHEAALERIGLKPLVQLEFQTGSGLGSATAVGLLK
TACAPFIAKPA

Sequences:

>Translated_331_residues
MSEPNRNKSPLDDVRDLILKPVETDPEAGRKVHEALLGMGREGDFGRLGEAAEWLATWQRRFPPRVEKPTLAIFAGSHGL
VDSGVSLSSNEDTRAHIEALKSGRAPLSAIATQVGANVRVFELALDKPTPSISETAAMSERECAATIAFGFEAVEDNPDL
LALAVSGAGVGTVAAAVACALYGGSPEYWVRPSAHTPAELSRKRVELVSAALKVHRGHLSDPLESLRCLGGREIAACVGA
IIAARHQGIPVLLDGFATTIAAGIVHAVSPQAVSHCLASHITQRPAHEAALERIGLKPLVQLEFQTGSGLGSATAVGLLK
TACAPFIAKPA
>Mature_330_residues
SEPNRNKSPLDDVRDLILKPVETDPEAGRKVHEALLGMGREGDFGRLGEAAEWLATWQRRFPPRVEKPTLAIFAGSHGLV
DSGVSLSSNEDTRAHIEALKSGRAPLSAIATQVGANVRVFELALDKPTPSISETAAMSERECAATIAFGFEAVEDNPDLL
ALAVSGAGVGTVAAAVACALYGGSPEYWVRPSAHTPAELSRKRVELVSAALKVHRGHLSDPLESLRCLGGREIAACVGAI
IAARHQGIPVLLDGFATTIAAGIVHAVSPQAVSHCLASHITQRPAHEAALERIGLKPLVQLEFQTGSGLGSATAVGLLKT
ACAPFIAKPA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=307, Percent_Identity=27.0358306188925, Blast_Score=111, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 34620; Mature: 34489

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPNRNKSPLDDVRDLILKPVETDPEAGRKVHEALLGMGREGDFGRLGEAAEWLATWQR
CCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RFPPRVEKPTLAIFAGSHGLVDSGVSLSSNEDTRAHIEALKSGRAPLSAIATQVGANVRV
HCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEE
FELALDKPTPSISETAAMSERECAATIAFGFEAVEDNPDLLALAVSGAGVGTVAAAVACA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHH
LYGGSPEYWVRPSAHTPAELSRKRVELVSAALKVHRGHLSDPLESLRCLGGREIAACVGA
HHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHH
IIAARHQGIPVLLDGFATTIAAGIVHAVSPQAVSHCLASHITQRPAHEAALERIGLKPLV
HHHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEE
QLEFQTGSGLGSATAVGLLKTACAPFIAKPA
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEPNRNKSPLDDVRDLILKPVETDPEAGRKVHEALLGMGREGDFGRLGEAAEWLATWQR
CCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
RFPPRVEKPTLAIFAGSHGLVDSGVSLSSNEDTRAHIEALKSGRAPLSAIATQVGANVRV
HCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEE
FELALDKPTPSISETAAMSERECAATIAFGFEAVEDNPDLLALAVSGAGVGTVAAAVACA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHH
LYGGSPEYWVRPSAHTPAELSRKRVELVSAALKVHRGHLSDPLESLRCLGGREIAACVGA
HHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHH
IIAARHQGIPVLLDGFATTIAAGIVHAVSPQAVSHCLASHITQRPAHEAALERIGLKPLV
HHHHHCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEE
QLEFQTGSGLGSATAVGLLKTACAPFIAKPA
EEEEECCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA