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The map label for this gene is hisC [H]

Identifier: 114799939

GI number: 114799939

Start: 83174

End: 84337

Strand: Direct

Name: hisC [H]

Synonym: HNE_0095

Alternate gene names: 114799939

Gene position: 83174-84337 (Clockwise)

Preceding gene: 114798288

Following gene: 114797960

Centisome position: 2.24

GC content: 58.33

Gene sequence:

>1164_bases
ATGACTTTAGTTCGTGAGACAGGGCTGCTGATGCCGTCACGGCGAAGCCTTATCAAGCTTGCCGGTGTGGGAGCAGGCGC
GCTTGGCGCGGCTGCAGCGCTGGCTGGCTGCTCTGAGTCGGCTGTTGCTGTTACGCCGGCCACTGCGCCGGTAGATCCCG
ATGCGATTGCCATCATGTCCTCGAATGAAAATCCCTATGGCCCGTCGCCGAAAGCAGTCGAGGCGATGAAAGCCGAGCTT
TCCAATATCAACCGCTATGCCAACGGTCTGACGGCCAAGTTTGCTGAAATGGTTGCCGCGCGGGAGGGCGTCGCGCCAGA
GCAGGTTCTGGTCACCAATGGATCAAATCCAATCCTGGCCGCCTTCGCAGACTGGGTGAATGTAAAGGGCGGCAAGATCG
TCACTTCCAAGATCACCTATGAAACTGTGGGCCGGGTTGCGCAGCAGGTTGGGACGGAGATTGTCGAAATTCCTCTGGAT
GCGGAGCTTGGATATGATCTTGAGGCCATTGCGGCCGCCGTGGGCCCCGACACCGGCGCCGTCTATATCTGCAATCCGAA
CAACCCAACGGGTCGTGTCATCGAGCCGGCTAAACTGAAGGCCTTCGTCGAAGACGTCAGCAGCAAGGTTCCGGTTTTCA
TCGACGAAGCGTATCTTGACCTGGCGGATGATTATCCGGCGGGCGTGATGAGCGAGTTTGTCAAAGCCGGTCGGCCAGTC
ATCGTGGCGCGGACTTTCTCCAAGCTTTACGCCATGGCAGGCCAGCGCCTGGGATATGGAATCATGCCGGCCGAGATCGC
TATGGATATCCGCAAATCCGGCCGTCTTTCGTCGGTCAATCATCTCGGTCTTGTCGCGGGCATCGCCAGCCTGGAAGACA
CGGTCTATTTTGAAGACATGCGGATGAAGCATGCGCTCGCCCGTCAGAAACTCATCGCAATGGCGAAGGATCTGGGCCGG
CCTATCGCGCCAGATCCGCAGGCGAGCTTTATCTATATGGATGTCGGTATGCCAGCCGGTGAGTTCTCCGCCAAAATGCT
GGAGAAGGGCGTGCGGGTTGTAGGCTCCCGCTGGCCTGAAATGCCCAACTGGTCACGCATATGCGTGGGTCTCGATCACG
AAATCGAGAAATGCCATGCGGCGGCCAAAGAAGTGCTCGCCTGA

Upstream 100 bases:

>100_bases
TCAAGTTGTCGCTGCGGAGCTTGGGGACAAAACCGTGAGTTGCCCGGAATTTTTCACCGGGGTCAGGCGCCCCGCACGCA
CTCTTGGAGGAATAAAGGTC

Downstream 100 bases:

>100_bases
TTCCTGCTTCGCGGGGGCTGTACTCAGCGCAATGGTTTCCGTTCCCGTCAGGGGCGGAAGCCGGTTTGCCTTTCGCCTGG
TTCGACAATACGCTGCGCAT

Product: classes I and II aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MTLVRETGLLMPSRRSLIKLAGVGAGALGAAAALAGCSESAVAVTPATAPVDPDAIAIMSSNENPYGPSPKAVEAMKAEL
SNINRYANGLTAKFAEMVAAREGVAPEQVLVTNGSNPILAAFADWVNVKGGKIVTSKITYETVGRVAQQVGTEIVEIPLD
AELGYDLEAIAAAVGPDTGAVYICNPNNPTGRVIEPAKLKAFVEDVSSKVPVFIDEAYLDLADDYPAGVMSEFVKAGRPV
IVARTFSKLYAMAGQRLGYGIMPAEIAMDIRKSGRLSSVNHLGLVAGIASLEDTVYFEDMRMKHALARQKLIAMAKDLGR
PIAPDPQASFIYMDVGMPAGEFSAKMLEKGVRVVGSRWPEMPNWSRICVGLDHEIEKCHAAAKEVLA

Sequences:

>Translated_387_residues
MTLVRETGLLMPSRRSLIKLAGVGAGALGAAAALAGCSESAVAVTPATAPVDPDAIAIMSSNENPYGPSPKAVEAMKAEL
SNINRYANGLTAKFAEMVAAREGVAPEQVLVTNGSNPILAAFADWVNVKGGKIVTSKITYETVGRVAQQVGTEIVEIPLD
AELGYDLEAIAAAVGPDTGAVYICNPNNPTGRVIEPAKLKAFVEDVSSKVPVFIDEAYLDLADDYPAGVMSEFVKAGRPV
IVARTFSKLYAMAGQRLGYGIMPAEIAMDIRKSGRLSSVNHLGLVAGIASLEDTVYFEDMRMKHALARQKLIAMAKDLGR
PIAPDPQASFIYMDVGMPAGEFSAKMLEKGVRVVGSRWPEMPNWSRICVGLDHEIEKCHAAAKEVLA
>Mature_386_residues
TLVRETGLLMPSRRSLIKLAGVGAGALGAAAALAGCSESAVAVTPATAPVDPDAIAIMSSNENPYGPSPKAVEAMKAELS
NINRYANGLTAKFAEMVAAREGVAPEQVLVTNGSNPILAAFADWVNVKGGKIVTSKITYETVGRVAQQVGTEIVEIPLDA
ELGYDLEAIAAAVGPDTGAVYICNPNNPTGRVIEPAKLKAFVEDVSSKVPVFIDEAYLDLADDYPAGVMSEFVKAGRPVI
VARTFSKLYAMAGQRLGYGIMPAEIAMDIRKSGRLSSVNHLGLVAGIASLEDTVYFEDMRMKHALARQKLIAMAKDLGRP
IAPDPQASFIYMDVGMPAGEFSAKMLEKGVRVVGSRWPEMPNWSRICVGLDHEIEKCHAAAKEVLA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=211, Percent_Identity=30.3317535545024, Blast_Score=85, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40975; Mature: 40844

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVRETGLLMPSRRSLIKLAGVGAGALGAAAALAGCSESAVAVTPATAPVDPDAIAIMS
CCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEE
SNENPYGPSPKAVEAMKAELSNINRYANGLTAKFAEMVAAREGVAPEQVLVTNGSNPILA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEE
AFADWVNVKGGKIVTSKITYETVGRVAQQVGTEIVEIPLDAELGYDLEAIAAAVGPDTGA
EHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCCCCE
VYICNPNNPTGRVIEPAKLKAFVEDVSSKVPVFIDEAYLDLADDYPAGVMSEFVKAGRPV
EEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCHHHHHHHHHCCCCE
IVARTFSKLYAMAGQRLGYGIMPAEIAMDIRKSGRLSSVNHLGLVAGIASLEDTVYFEDM
EEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RMKHALARQKLIAMAKDLGRPIAPDPQASFIYMDVGMPAGEFSAKMLEKGVRVVGSRWPE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
MPNWSRICVGLDHEIEKCHAAAKEVLA
CCCCCEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLVRETGLLMPSRRSLIKLAGVGAGALGAAAALAGCSESAVAVTPATAPVDPDAIAIMS
CCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEEE
SNENPYGPSPKAVEAMKAELSNINRYANGLTAKFAEMVAAREGVAPEQVLVTNGSNPILA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEE
AFADWVNVKGGKIVTSKITYETVGRVAQQVGTEIVEIPLDAELGYDLEAIAAAVGPDTGA
EHHHHHCCCCCEEEEEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHCCCCCCE
VYICNPNNPTGRVIEPAKLKAFVEDVSSKVPVFIDEAYLDLADDYPAGVMSEFVKAGRPV
EEEECCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCHHHHHHHHHCCCCE
IVARTFSKLYAMAGQRLGYGIMPAEIAMDIRKSGRLSSVNHLGLVAGIASLEDTVYFEDM
EEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RMKHALARQKLIAMAKDLGRPIAPDPQASFIYMDVGMPAGEFSAKMLEKGVRVVGSRWPE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCC
MPNWSRICVGLDHEIEKCHAAAKEVLA
CCCCCEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA