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The map label for this gene is gltB [H]

Identifier: 114798288

GI number: 114798288

Start: 77412

End: 81953

Strand: Direct

Name: gltB [H]

Synonym: HNE_0093

Alternate gene names: 114798288

Gene position: 77412-81953 (Clockwise)

Preceding gene: 114800319

Following gene: 114799939

Centisome position: 2.09

GC content: 61.05

Gene sequence:

>4542_bases
ATGTCGGATTATGTGACCAAGTATGAGCAAAACCGTCAGCGCCTGATCGACGGGCATGCCTACAATCCCGAGGACGAACG
CGACGCTTGCGGCGTGGGCCTCGTTGTGGCGCTGGATGGAAAGCCCCGCCGCGAGATCGTCGAGATGGGGATCAAGGCGC
TCAAGAATGTCTGGCATCGCGGCGCTGTGGATGCTGACGGCAAAACGGGCGATGGCGCAGGCATCCGCCTCGACGTGCCG
CAGGACTTTTTCCGCGAGCATGTGAGCCGCACAGGCCACAGCCCGACGGATGACCGTATCTGCGTCGGCCAGATCTTCAT
GCCGCGCACGGATTTCGGCGCGCAGGAAGCGGCGCGCACGCTGGTTGAACGCGAAGTGCTGCATTTCGGCTTCTATATCT
ATGGCTGGCGCCAGCCGCCGGTAGATGTGTCCGTGATCGGACAGAAAGCGAAAGACACCCGCCCCGCAATTGAGCAGATC
ATGTTCCGGGACGCGCGCAACCGCTCGCCCGAGGAACTTGAGCGTGCGCTGTATATCTGCCGCCGGCGGATCGAGCGGCG
GGCACGTGAGGCGGCGATCCAGTCTTTCTATATCTGCTCGCTCAGCCACAAATCGCTGATCTATAAAGGCATGTTCCTGG
CGCAGGACATCGACAATTTCTATCTCGACCTGCGCGACGAACGGTTCGTGTCGGCCTTTGCGATCTATCACCAGCGCTAC
TCGACCAACACATTCCCGCAATGGGCGCTAGCCCAGCCTTTCCGCACCATTGCGCACAATGGCGAAATCAACACGCTGCG
CGGCAACCGCAACTGGATGAAAAGCCATGAAATCCGCATGGTCTCGGAAACCTTCGGCGACCATACGCAGGATGTGAAGC
CGGTGATCCCGGATGGTACATCAGACTCCGGCGCGCTGGATGCTGTATGGGAACTGCTCTGCAAATCTGGCCGCCCGGCG
CCGATGGCGAAGGCGATGCTGATTCCCGAAGCCTGGTCCAAGCGGGATTCCGTCATGCCGGTCGCTCACCGCGCGCTCTA
TGATTACTGCAATTCCGTGATGGAGCCGTGGGACGGGCCAGCTGCAATCGCTGCCTATGATGGCCGCTGGGCGGTCGCCG
GCCTTGACCGCAACGGCCTGCGTCCACTGCGGTATTCTCTGACGACTGACGGCATTCTTGCCGTTGGCTCTGAGACAGGT
ATGTGCCCGCTCGGCAATCACGAAGTCACGCGCCGCGGATCAATTCCCGCCGGTGGCATGATCGCGGCCGATCTTGCCAC
AGGGAAATTCTACGACCACCGCGAGATTGTCGACTTCCTTGCTGCTCAGGCCCCGTATGAGGAATGGCTGCAGGCGGTCA
CTGAACTGGAGCCTGAAATCGGTCCTGGTCCGGAACCTGTGCTGTTTAACAAAGAAGAGTTGCTGCGCCGGGAAACGGCC
GCCGGCTATACGCTTGAAACGCTCGAGCTGATCCTGGCGCCGATGGTGGAAGGCGGCAAGGAAGCGCTCGGCTCGATGGG
GGATGATACCGCGCCCGCCGTTCTGACAATGGCCTACCGGCCGATGAGTCACTTCTTCCGGCAGAATTTCAGCCAGGTCA
CGAACCCGCCGATCGACCCGCTGCGCGAAGGCCGGGTGATGAGCCTGCGCACCCGGTTCAAGAACCTTGGAAACGTGTTG
GATACGGATAAATCCCAGCAGGAAGTTTTCGTGCTGGAAAGCCCGGTCCTGACGACGGGTATGTATCAGCGCCTGATCGA
GCGGATCGGTCTGGGTACGGAGATCATCGATTGCACGTTCGATGCTGCCGATGTGACTTTCGAGGGCGCTGCCCTCAAGA
GCGCGCTGGAGCGTATCCGCCGCGAGGCCGAAGAGGCCGTACGGGCAGGGCGCGAGCACATCATCCTCACGGATGAAAAC
CAGTCAGCCAGCCGCATTGCTGTCCCGATGGTTCTGGCAACAGGCGCCGTGCACTCGCATCTCGTCGCCCAGGGTCTGCG
CACCTTCTGCTCGATCACAGTGCGTTCGGCCGAATGTCTCGATACGCATTATTTTGCCGTTCTGGTCGGCGTGGGCGCAA
CCTGCGTCAATGCCTACCTGGCGCAGGACGCAATTGCCGACCGGCATGCACGCGGCTTGCTGGGAGACATCTCCATCGGC
AAGGCAGTTCAAAACTACAAGGAGGCCATCGAGGCGGGCCTTCTGAAAATCATCTCAAAGATGGGTATCTCGGTTATCTC
GTCCTATCGGGGCGGATATAATTTCGAAGCGCTTGGTCTCTCGCGCGCGTTGGTGGCCGATTATTTCCCCGGCATGTCGA
GCCGTATTTCCGGTCTGGGTCTTGCCGGTCTGGAGGAGAACGCGCTCGTTCGCCATCAGCAGGCCTTTGATGAGGATGTC
ATCTCGCTTCCTGTCGGCGGCTTCTATCGCCTGCGTGCGTCTGACGAGCCGCACGCGCTCGACGGGAACCTGATCCATAC
GCTTCAGGCGGCCTGTGACCGGGGCGACTATTCGATCTACCGGAAATATGTGGACGCCGTTCACGCCCGCGATCCGCTGC
AATTGCGCGATCTTCTCGACTTCAAGGCTGCCGGTCCGGAAGTACCGTTGAGCCAGGTCCAGTCGATCAACGAAATTCGC
AAGCGTTTCCTGACGCCGGGCATGTCTATGGGCGCTCTGTCGCCTGAGGCGCATGGCACATTGAACGTTGCCATGAACCG
GATTGGTGCAAAGTCCGTATCCGGAGAGGGCGGGGAAGACCGCGCTCGCTATCGGCCGTTGCCAAACGGTGACAACATGA
ACTCTGCGGTGAAACAGATCGCGTCGGGACGTTTCGGGGTTACTGCCGAGTATCTCAATGAATGCCGTGAGATCGAGATC
AAGGTCGCCCAGGGCGCCAAGCCCGGCGAGGGGGGCCAGTTGCCTGGTTTCAAGGTTACTGAACTGATCGCGAAGCTCCG
GCACGCGACGCCCGGCGTGACGCTGATTTCGCCGCCGCCCCATCATGACATCTATTCGATCGAAGATCTGGCGCAGCTGA
TCTACGACCTGAAGCAGATCAATCCTGAAGCGCGCGTCTGCGTGAAGCTTGTGGCGCAATCCGGCGTCGGCACGGTGGCC
GCTGGCGTGGCGAAAGCCAAAGCGGACATCATTCTGATTGCCGGCGGCGTTGGCGGTACGGGGGCCAGCCCTCAGACCTC
AATCAAATATGCCGGCCTGCCCTGGGAGATCGGCCTTGCCGAAGCCCACCAGATTCTGTCGCTCAACAATCTGCGCGACA
AGATCACTCTGCGCACGGATGGCGGGCTGCGGACAGGCCGCGACATTGTCATCGCGGCGATGCTTGGCGCTGAAGAATAT
GGCATTGGCACAGCATCGCTTGTGGCGATGGGATGTATCATGGTGCGCCAGTGTCACTCTAACACGTGCCCCGTTGGCGT
CTGTACCCAGGACGAAGCGCTGCGTGCCCACTTCACCGGCAATCCGGACAAGGTGGTCAACCTGATGAGCTTCATTGCCG
AGGATGTTCGGGAAATTCTCGCCTCCCTGGGCCTGACCTCTCTGGATGAAGCCATTGGGCGCACGGACCTGCTCAAACAG
GTCAGCCGCGGCGCGACCCATCTGGATGACCTCGACCTCAACCCGCTTCTGGTGCAGGTCGATACGGACAGTCCGGTTAT
CTACAAGCCCAATCACCGCGAGCCTGTGCCCGATACGCTCGACGCGCAGATCCTGCGGGACGCTGAACCCTTCTTCGAGC
GCGGCGAGAAGATGCAGCTGGAATACGGCGTTCAGAACACGATGCGGGCCATTGGGGCGCGGGCCAGCTCGCGGATCACC
CGGAAGTTCGGGATGCATGCACTGCCCGAAGGCCGCCTGCATATCCGGCTCGAGGGCTCGGCAGGCCAGTCACTCGGCGC
GTTCAGCGTTCAGGGGCTGCTGCTGGAAGTTCTGGGTGATGCCAACGATTATGTTGGCAAGGGCCTGTCCGGCGCGAGCA
TTGTGGTCACGCCGCGTCCCCGCGACAGGCGGGCAGCAGTTGGTGACGCCATCATCGGCAACACATGCCTCTACGGCGCA
ACTTCCGGCAAGCTCTTTGCGGCCGGCACGGCAGGCGTGCGCTTTGCCGTGCGCAACTCCGGCGCAAAGACTGTTGTTGA
GGGGTGCGGCGCCAATGGCTGCGAATACATGACCGGCGGCCGCGCGGTCATTCTTGGGCCAGTTGGTGATAACTTCGGCG
CCGGCATGACAGGCGGTGTGGGCTTTATCTGGGATCCGCAGGAACGCTTTGAGCGAGTGGTGAACCCGGATTCGATCGAT
TGGTATCCGCTTGCAGACATGCCGGATGAGTATGTCGGCGAGGCGAAGGCGCTGATCGAAGAGCATGTCCGCCGCACAGG
CTCTGTTCGCGGCAAGGAGCTGCTTGATGCCTGGGATACAACCCTCAGCCAGATGCTGATGATCGTGCCAAAGGAAATCG
CAAACCTCCTGCTTGTCCGCAAGGGCGATGGCGCCAAGCAGAAGCAGGCCGAGCGGGCCTGA

Upstream 100 bases:

>100_bases
TCGTCTGGGCGATCAAGGATGGCCGCGACGCGGCCGAAGCGATGCACAAGGCAATGAGGGCCGCTGAGGCGGCCGCAAAA
GTGGCGGCGGAGTAAGTCAG

Downstream 100 bases:

>100_bases
TACCCGCTCAGCGAATTTAGCAACATCAGCGCCTGGTCCGGAGACGGATCAGGCGTTTGGCTTTTTACGGCGAATGCGGG
GCCAGATCAGCCGCAGCCAG

Product: glutamate synthase large subunit

Products: NA

Alternate protein names: Glutamate synthase subunit alpha; GLTS alpha chain; NADPH-GOGAT [H]

Number of amino acids: Translated: 1513; Mature: 1512

Protein sequence:

>1513_residues
MSDYVTKYEQNRQRLIDGHAYNPEDERDACGVGLVVALDGKPRREIVEMGIKALKNVWHRGAVDADGKTGDGAGIRLDVP
QDFFREHVSRTGHSPTDDRICVGQIFMPRTDFGAQEAARTLVEREVLHFGFYIYGWRQPPVDVSVIGQKAKDTRPAIEQI
MFRDARNRSPEELERALYICRRRIERRAREAAIQSFYICSLSHKSLIYKGMFLAQDIDNFYLDLRDERFVSAFAIYHQRY
STNTFPQWALAQPFRTIAHNGEINTLRGNRNWMKSHEIRMVSETFGDHTQDVKPVIPDGTSDSGALDAVWELLCKSGRPA
PMAKAMLIPEAWSKRDSVMPVAHRALYDYCNSVMEPWDGPAAIAAYDGRWAVAGLDRNGLRPLRYSLTTDGILAVGSETG
MCPLGNHEVTRRGSIPAGGMIAADLATGKFYDHREIVDFLAAQAPYEEWLQAVTELEPEIGPGPEPVLFNKEELLRRETA
AGYTLETLELILAPMVEGGKEALGSMGDDTAPAVLTMAYRPMSHFFRQNFSQVTNPPIDPLREGRVMSLRTRFKNLGNVL
DTDKSQQEVFVLESPVLTTGMYQRLIERIGLGTEIIDCTFDAADVTFEGAALKSALERIRREAEEAVRAGREHIILTDEN
QSASRIAVPMVLATGAVHSHLVAQGLRTFCSITVRSAECLDTHYFAVLVGVGATCVNAYLAQDAIADRHARGLLGDISIG
KAVQNYKEAIEAGLLKIISKMGISVISSYRGGYNFEALGLSRALVADYFPGMSSRISGLGLAGLEENALVRHQQAFDEDV
ISLPVGGFYRLRASDEPHALDGNLIHTLQAACDRGDYSIYRKYVDAVHARDPLQLRDLLDFKAAGPEVPLSQVQSINEIR
KRFLTPGMSMGALSPEAHGTLNVAMNRIGAKSVSGEGGEDRARYRPLPNGDNMNSAVKQIASGRFGVTAEYLNECREIEI
KVAQGAKPGEGGQLPGFKVTELIAKLRHATPGVTLISPPPHHDIYSIEDLAQLIYDLKQINPEARVCVKLVAQSGVGTVA
AGVAKAKADIILIAGGVGGTGASPQTSIKYAGLPWEIGLAEAHQILSLNNLRDKITLRTDGGLRTGRDIVIAAMLGAEEY
GIGTASLVAMGCIMVRQCHSNTCPVGVCTQDEALRAHFTGNPDKVVNLMSFIAEDVREILASLGLTSLDEAIGRTDLLKQ
VSRGATHLDDLDLNPLLVQVDTDSPVIYKPNHREPVPDTLDAQILRDAEPFFERGEKMQLEYGVQNTMRAIGARASSRIT
RKFGMHALPEGRLHIRLEGSAGQSLGAFSVQGLLLEVLGDANDYVGKGLSGASIVVTPRPRDRRAAVGDAIIGNTCLYGA
TSGKLFAAGTAGVRFAVRNSGAKTVVEGCGANGCEYMTGGRAVILGPVGDNFGAGMTGGVGFIWDPQERFERVVNPDSID
WYPLADMPDEYVGEAKALIEEHVRRTGSVRGKELLDAWDTTLSQMLMIVPKEIANLLLVRKGDGAKQKQAERA

Sequences:

>Translated_1513_residues
MSDYVTKYEQNRQRLIDGHAYNPEDERDACGVGLVVALDGKPRREIVEMGIKALKNVWHRGAVDADGKTGDGAGIRLDVP
QDFFREHVSRTGHSPTDDRICVGQIFMPRTDFGAQEAARTLVEREVLHFGFYIYGWRQPPVDVSVIGQKAKDTRPAIEQI
MFRDARNRSPEELERALYICRRRIERRAREAAIQSFYICSLSHKSLIYKGMFLAQDIDNFYLDLRDERFVSAFAIYHQRY
STNTFPQWALAQPFRTIAHNGEINTLRGNRNWMKSHEIRMVSETFGDHTQDVKPVIPDGTSDSGALDAVWELLCKSGRPA
PMAKAMLIPEAWSKRDSVMPVAHRALYDYCNSVMEPWDGPAAIAAYDGRWAVAGLDRNGLRPLRYSLTTDGILAVGSETG
MCPLGNHEVTRRGSIPAGGMIAADLATGKFYDHREIVDFLAAQAPYEEWLQAVTELEPEIGPGPEPVLFNKEELLRRETA
AGYTLETLELILAPMVEGGKEALGSMGDDTAPAVLTMAYRPMSHFFRQNFSQVTNPPIDPLREGRVMSLRTRFKNLGNVL
DTDKSQQEVFVLESPVLTTGMYQRLIERIGLGTEIIDCTFDAADVTFEGAALKSALERIRREAEEAVRAGREHIILTDEN
QSASRIAVPMVLATGAVHSHLVAQGLRTFCSITVRSAECLDTHYFAVLVGVGATCVNAYLAQDAIADRHARGLLGDISIG
KAVQNYKEAIEAGLLKIISKMGISVISSYRGGYNFEALGLSRALVADYFPGMSSRISGLGLAGLEENALVRHQQAFDEDV
ISLPVGGFYRLRASDEPHALDGNLIHTLQAACDRGDYSIYRKYVDAVHARDPLQLRDLLDFKAAGPEVPLSQVQSINEIR
KRFLTPGMSMGALSPEAHGTLNVAMNRIGAKSVSGEGGEDRARYRPLPNGDNMNSAVKQIASGRFGVTAEYLNECREIEI
KVAQGAKPGEGGQLPGFKVTELIAKLRHATPGVTLISPPPHHDIYSIEDLAQLIYDLKQINPEARVCVKLVAQSGVGTVA
AGVAKAKADIILIAGGVGGTGASPQTSIKYAGLPWEIGLAEAHQILSLNNLRDKITLRTDGGLRTGRDIVIAAMLGAEEY
GIGTASLVAMGCIMVRQCHSNTCPVGVCTQDEALRAHFTGNPDKVVNLMSFIAEDVREILASLGLTSLDEAIGRTDLLKQ
VSRGATHLDDLDLNPLLVQVDTDSPVIYKPNHREPVPDTLDAQILRDAEPFFERGEKMQLEYGVQNTMRAIGARASSRIT
RKFGMHALPEGRLHIRLEGSAGQSLGAFSVQGLLLEVLGDANDYVGKGLSGASIVVTPRPRDRRAAVGDAIIGNTCLYGA
TSGKLFAAGTAGVRFAVRNSGAKTVVEGCGANGCEYMTGGRAVILGPVGDNFGAGMTGGVGFIWDPQERFERVVNPDSID
WYPLADMPDEYVGEAKALIEEHVRRTGSVRGKELLDAWDTTLSQMLMIVPKEIANLLLVRKGDGAKQKQAERA
>Mature_1512_residues
SDYVTKYEQNRQRLIDGHAYNPEDERDACGVGLVVALDGKPRREIVEMGIKALKNVWHRGAVDADGKTGDGAGIRLDVPQ
DFFREHVSRTGHSPTDDRICVGQIFMPRTDFGAQEAARTLVEREVLHFGFYIYGWRQPPVDVSVIGQKAKDTRPAIEQIM
FRDARNRSPEELERALYICRRRIERRAREAAIQSFYICSLSHKSLIYKGMFLAQDIDNFYLDLRDERFVSAFAIYHQRYS
TNTFPQWALAQPFRTIAHNGEINTLRGNRNWMKSHEIRMVSETFGDHTQDVKPVIPDGTSDSGALDAVWELLCKSGRPAP
MAKAMLIPEAWSKRDSVMPVAHRALYDYCNSVMEPWDGPAAIAAYDGRWAVAGLDRNGLRPLRYSLTTDGILAVGSETGM
CPLGNHEVTRRGSIPAGGMIAADLATGKFYDHREIVDFLAAQAPYEEWLQAVTELEPEIGPGPEPVLFNKEELLRRETAA
GYTLETLELILAPMVEGGKEALGSMGDDTAPAVLTMAYRPMSHFFRQNFSQVTNPPIDPLREGRVMSLRTRFKNLGNVLD
TDKSQQEVFVLESPVLTTGMYQRLIERIGLGTEIIDCTFDAADVTFEGAALKSALERIRREAEEAVRAGREHIILTDENQ
SASRIAVPMVLATGAVHSHLVAQGLRTFCSITVRSAECLDTHYFAVLVGVGATCVNAYLAQDAIADRHARGLLGDISIGK
AVQNYKEAIEAGLLKIISKMGISVISSYRGGYNFEALGLSRALVADYFPGMSSRISGLGLAGLEENALVRHQQAFDEDVI
SLPVGGFYRLRASDEPHALDGNLIHTLQAACDRGDYSIYRKYVDAVHARDPLQLRDLLDFKAAGPEVPLSQVQSINEIRK
RFLTPGMSMGALSPEAHGTLNVAMNRIGAKSVSGEGGEDRARYRPLPNGDNMNSAVKQIASGRFGVTAEYLNECREIEIK
VAQGAKPGEGGQLPGFKVTELIAKLRHATPGVTLISPPPHHDIYSIEDLAQLIYDLKQINPEARVCVKLVAQSGVGTVAA
GVAKAKADIILIAGGVGGTGASPQTSIKYAGLPWEIGLAEAHQILSLNNLRDKITLRTDGGLRTGRDIVIAAMLGAEEYG
IGTASLVAMGCIMVRQCHSNTCPVGVCTQDEALRAHFTGNPDKVVNLMSFIAEDVREILASLGLTSLDEAIGRTDLLKQV
SRGATHLDDLDLNPLLVQVDTDSPVIYKPNHREPVPDTLDAQILRDAEPFFERGEKMQLEYGVQNTMRAIGARASSRITR
KFGMHALPEGRLHIRLEGSAGQSLGAFSVQGLLLEVLGDANDYVGKGLSGASIVVTPRPRDRRAAVGDAIIGNTCLYGAT
SGKLFAAGTAGVRFAVRNSGAKTVVEGCGANGCEYMTGGRAVILGPVGDNFGAGMTGGVGFIWDPQERFERVVNPDSIDW
YPLADMPDEYVGEAKALIEEHVRRTGSVRGKELLDAWDTTLSQMLMIVPKEIANLLLVRKGDGAKQKQAERA

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0069

COG function: function code E; Glutamate synthase domain 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI308199519, Length=1488, Percent_Identity=44.1532258064516, Blast_Score=1129, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17570289, Length=1562, Percent_Identity=40.0768245838668, Blast_Score=1044, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320030, Length=1523, Percent_Identity=40.5778069599475, Blast_Score=1091, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574881, Length=1529, Percent_Identity=40.2877697841727, Blast_Score=1053, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665539, Length=1529, Percent_Identity=40.2877697841727, Blast_Score=1053, Evalue=0.0,
Organism=Drosophila melanogaster, GI24665547, Length=389, Percent_Identity=40.1028277634961, Blast_Score=277, Evalue=3e-74,
Organism=Drosophila melanogaster, GI24665543, Length=389, Percent_Identity=40.1028277634961, Blast_Score=277, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR002932
- InterPro:   IPR006982
- InterPro:   IPR002489 [H]

Pfam domain/function: PF00310 GATase_2; PF04898 Glu_syn_central; PF01645 Glu_synthase; PF01493 GXGXG [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 165168; Mature: 165037

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYVTKYEQNRQRLIDGHAYNPEDERDACGVGLVVALDGKPRREIVEMGIKALKNVWHR
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHC
GAVDADGKTGDGAGIRLDVPQDFFREHVSRTGHSPTDDRICVGQIFMPRTDFGAQEAART
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHH
LVEREVLHFGFYIYGWRQPPVDVSVIGQKAKDTRPAIEQIMFRDARNRSPEELERALYIC
HHHHHHHHHCEEEEECCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
RRRIERRAREAAIQSFYICSLSHKSLIYKGMFLAQDIDNFYLDLRDERFVSAFAIYHQRY
HHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHH
STNTFPQWALAQPFRTIAHNGEINTLRGNRNWMKSHEIRMVSETFGDHTQDVKPVIPDGT
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHEEHHHHHCCCCCCCCCCCCCCC
SDSGALDAVWELLCKSGRPAPMAKAMLIPEAWSKRDSVMPVAHRALYDYCNSVMEPWDGP
CCCCHHHHHHHHHHHCCCCCCHHHHEECCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
AAIAAYDGRWAVAGLDRNGLRPLRYSLTTDGILAVGSETGMCPLGNHEVTRRGSIPAGGM
EEEEEECCCEEEEECCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCE
IAADLATGKFYDHREIVDFLAAQAPYEEWLQAVTELEPEIGPGPEPVLFNKEELLRRETA
EEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHH
AGYTLETLELILAPMVEGGKEALGSMGDDTAPAVLTMAYRPMSHFFRQNFSQVTNPPIDP
CCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LREGRVMSLRTRFKNLGNVLDTDKSQQEVFVLESPVLTTGMYQRLIERIGLGTEIIDCTF
HHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEE
DAADVTFEGAALKSALERIRREAEEAVRAGREHIILTDENQSASRIAVPMVLATGAVHSH
CCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
LVAQGLRTFCSITVRSAECLDTHYFAVLVGVGATCVNAYLAQDAIADRHARGLLGDISIG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
KAVQNYKEAIEAGLLKIISKMGISVISSYRGGYNFEALGLSRALVADYFPGMSSRISGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCHHHHHCCCC
LAGLEENALVRHQQAFDEDVISLPVGGFYRLRASDEPHALDGNLIHTLQAACDRGDYSIY
CCCCCCHHHHHHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHH
RKYVDAVHARDPLQLRDLLDFKAAGPEVPLSQVQSINEIRKRFLTPGMSMGALSPEAHGT
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
LNVAMNRIGAKSVSGEGGEDRARYRPLPNGDNMNSAVKQIASGRFGVTAEYLNECREIEI
HHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHEEEE
KVAQGAKPGEGGQLPGFKVTELIAKLRHATPGVTLISPPPHHDIYSIEDLAQLIYDLKQI
EEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHC
NPEARVCVKLVAQSGVGTVAAGVAKAKADIILIAGGVGGTGASPQTSIKYAGLPWEIGLA
CHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCHH
EAHQILSLNNLRDKITLRTDGGLRTGRDIVIAAMLGAEEYGIGTASLVAMGCIMVRQCHS
HHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHHHCC
NTCPVGVCTQDEALRAHFTGNPDKVVNLMSFIAEDVREILASLGLTSLDEAIGRTDLLKQ
CCCCEEEECCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHH
VSRGATHLDDLDLNPLLVQVDTDSPVIYKPNHREPVPDTLDAQILRDAEPFFERGEKMQL
HHCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHHHHCCCHHHHCCCEEEE
EYGVQNTMRAIGARASSRITRKFGMHALPEGRLHIRLEGSAGQSLGAFSVQGLLLEVLGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCC
ANDYVGKGLSGASIVVTPRPRDRRAAVGDAIIGNTCLYGATSGKLFAAGTAGVRFAVRNS
CHHHHCCCCCCCEEEEECCCCCCHHHHCCHHHCCCEEECCCCCCEEEECCCCEEEEEECC
GAKTVVEGCGANGCEYMTGGRAVILGPVGDNFGAGMTGGVGFIWDPQERFERVVNPDSID
CCHHHHHCCCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHCCCCCCC
WYPLADMPDEYVGEAKALIEEHVRRTGSVRGKELLDAWDTTLSQMLMIVPKEIANLLLVR
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEE
KGDGAKQKQAERA
CCCCCHHHHHCCC
>Mature Secondary Structure 
SDYVTKYEQNRQRLIDGHAYNPEDERDACGVGLVVALDGKPRREIVEMGIKALKNVWHR
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHC
GAVDADGKTGDGAGIRLDVPQDFFREHVSRTGHSPTDDRICVGQIFMPRTDFGAQEAART
CCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHH
LVEREVLHFGFYIYGWRQPPVDVSVIGQKAKDTRPAIEQIMFRDARNRSPEELERALYIC
HHHHHHHHHCEEEEECCCCCCCHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
RRRIERRAREAAIQSFYICSLSHKSLIYKGMFLAQDIDNFYLDLRDERFVSAFAIYHQRY
HHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHH
STNTFPQWALAQPFRTIAHNGEINTLRGNRNWMKSHEIRMVSETFGDHTQDVKPVIPDGT
CCCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHEEHHHHHCCCCCCCCCCCCCCC
SDSGALDAVWELLCKSGRPAPMAKAMLIPEAWSKRDSVMPVAHRALYDYCNSVMEPWDGP
CCCCHHHHHHHHHHHCCCCCCHHHHEECCHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCC
AAIAAYDGRWAVAGLDRNGLRPLRYSLTTDGILAVGSETGMCPLGNHEVTRRGSIPAGGM
EEEEEECCCEEEEECCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCE
IAADLATGKFYDHREIVDFLAAQAPYEEWLQAVTELEPEIGPGPEPVLFNKEELLRRETA
EEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEECHHHHHHHHHH
AGYTLETLELILAPMVEGGKEALGSMGDDTAPAVLTMAYRPMSHFFRQNFSQVTNPPIDP
CCCHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCH
LREGRVMSLRTRFKNLGNVLDTDKSQQEVFVLESPVLTTGMYQRLIERIGLGTEIIDCTF
HHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEE
DAADVTFEGAALKSALERIRREAEEAVRAGREHIILTDENQSASRIAVPMVLATGAVHSH
CCCCCEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHH
LVAQGLRTFCSITVRSAECLDTHYFAVLVGVGATCVNAYLAQDAIADRHARGLLGDISIG
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
KAVQNYKEAIEAGLLKIISKMGISVISSYRGGYNFEALGLSRALVADYFPGMSSRISGLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCHHHHHCCCC
LAGLEENALVRHQQAFDEDVISLPVGGFYRLRASDEPHALDGNLIHTLQAACDRGDYSIY
CCCCCCHHHHHHHHHHCCHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHH
RKYVDAVHARDPLQLRDLLDFKAAGPEVPLSQVQSINEIRKRFLTPGMSMGALSPEAHGT
HHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
LNVAMNRIGAKSVSGEGGEDRARYRPLPNGDNMNSAVKQIASGRFGVTAEYLNECREIEI
HHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHEEEE
KVAQGAKPGEGGQLPGFKVTELIAKLRHATPGVTLISPPPHHDIYSIEDLAQLIYDLKQI
EEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHC
NPEARVCVKLVAQSGVGTVAAGVAKAKADIILIAGGVGGTGASPQTSIKYAGLPWEIGLA
CHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCHH
EAHQILSLNNLRDKITLRTDGGLRTGRDIVIAAMLGAEEYGIGTASLVAMGCIMVRQCHS
HHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCHHCCCCHHHHHHHHHHHHHHHCC
NTCPVGVCTQDEALRAHFTGNPDKVVNLMSFIAEDVREILASLGLTSLDEAIGRTDLLKQ
CCCCEEEECCCCHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCHHHHHHH
VSRGATHLDDLDLNPLLVQVDTDSPVIYKPNHREPVPDTLDAQILRDAEPFFERGEKMQL
HHCCCCCCCCCCCCCEEEEECCCCCEEECCCCCCCCCCCHHHHHHHCCCHHHHCCCEEEE
EYGVQNTMRAIGARASSRITRKFGMHALPEGRLHIRLEGSAGQSLGAFSVQGLLLEVLGD
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCC
ANDYVGKGLSGASIVVTPRPRDRRAAVGDAIIGNTCLYGATSGKLFAAGTAGVRFAVRNS
CHHHHCCCCCCCEEEEECCCCCCHHHHCCHHHCCCEEECCCCCCEEEECCCCEEEEEECC
GAKTVVEGCGANGCEYMTGGRAVILGPVGDNFGAGMTGGVGFIWDPQERFERVVNPDSID
CCHHHHHCCCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCEEECCHHHHHHHCCCCCCC
WYPLADMPDEYVGEAKALIEEHVRRTGSVRGKELLDAWDTTLSQMLMIVPKEIANLLLVR
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEEE
KGDGAKQKQAERA
CCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8428988; 7902833; 2198943 [H]