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The map label for this gene is ectB [H]

Identifier: 114799897

GI number: 114799897

Start: 1676795

End: 1678090

Strand: Direct

Name: ectB [H]

Synonym: HNE_1640

Alternate gene names: 114799897

Gene position: 1676795-1678090 (Clockwise)

Preceding gene: 114797806

Following gene: 114799353

Centisome position: 45.26

GC content: 60.34

Gene sequence:

>1296_bases
ATGGCCTACGAACACGCATCTGCACCCGCAAATATTTTTGAGCGCCGCGAATCCCGTGTGCGCAGCTATTGCCGGTCTTT
CCCGGCGGTCTTCAAATCCGCACGCGGATCAGAGTTGATCGCTGAAGACGGCACACGCTACATCGACTTTCTGTCCGGCT
GTTCCACGCTGAACTACGGCCACAACCATCCCGAGCTGAAACAGGCCCTCCTGGACTATATCGGCGCGGACGGCGTGGCG
CACGGCCTCGATATGCACACGCGTGCAAAGGCCCGTTTTCTGAACACTTTCGAGCGGCTTATCCTCAAGCCACGCAGCAT
GGATCACCGCGTCCTCTTTCCGGGGCCAACAGGTGCCAACGCTGTAGAGGCTGCTCTGAAGACCGCCCGTAAAGTCACGG
GGCGGACAAATGTAATTGCCTTCACCAACGGCTTCCATGGCATGACGCTTGGCGCCCTCGCTGCGACGGGCAATTCCGGC
AAGCGCGGCGGGGCAGGTGTGCCGCTCACGGGCGTGACGCATGAAGCCTTTGATGGCTATTTCGGTGAGGATACCGACAC
GGCTGACCAGCTGGATCGCCGCCTGTCTGACCCCTCTTCGGGGCTCGACAAACCGGCTGCCATCATTGTGGAAACCGTGC
AGGGCGAAGGCGGATTGAATGTCGCGTCTGATGCCTGGCTGCGCAAGATCGAGAAGATCGCCCGCAAGCATGGCGCCCTC
TTCATTATTGATGACATCCAGGCGGGCATTGGCCGCACAGGTGGCTTCTTCAGCTTCGAAAAAGCAGGTGTTACGCCGGA
TATTATCACGATGGCCAAGTCCCTCTCGGGCCTGGGTCTGCCCTTCGCGCTGACATTGATCCGCCCACAGCATGATCTTT
GGAAGCCCGGTGAGCACAACGGCACGTTCCGTGGCAACAACCATGCCTTCGTGACGGCAACCAAGGCGCTGGAACTGTTC
TGGGCCGATGATGCCTTCGAGAAGGAAACCGCTCGCAAGGCCGCGCGTCTTCGCGCCGGCTTGGAAAAGATCGCTGCTTC
CGCATCGTTCGCTGGCCGGCTGAAAGGCAAGGGCATGATGTCCGGCATCGAGATGGAAAGCGGAGACGTGGCGGCCGAGA
TTTGCACCGAATGCTTCCAGAACGGCCTCATTATCGAAACCAGCGGCAGCATGGATGAAGTCGTCAAGGTGCTCGCCCCG
CTCACCATCACCGATGCCGAATTGGATGCCGGCCTCAAAATTCTTGCGGACGCCGTGCGCGCGGTCAGCGCGCGCCGCCA
GAAGTCCGCAGCCTGA

Upstream 100 bases:

>100_bases
CACCGAATTCCTCGTGACCATTGGCCCTTTCGAGGCGCCAGCGGCTTCTGGCTGACCCCTTCAGCCGACTGTAGAAATCA
GAGCAAAAAAGGAGCCATAA

Downstream 100 bases:

>100_bases
AGGAGATAAAAATGATTGTTAGAGACCTCGCAAAAGAAATCCTTACAGACCGCCGCGTGGACAGCGACGGCTGGTCTTCC
GTTCGCCTGCTGCTGAAAGA

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MAYEHASAPANIFERRESRVRSYCRSFPAVFKSARGSELIAEDGTRYIDFLSGCSTLNYGHNHPELKQALLDYIGADGVA
HGLDMHTRAKARFLNTFERLILKPRSMDHRVLFPGPTGANAVEAALKTARKVTGRTNVIAFTNGFHGMTLGALAATGNSG
KRGGAGVPLTGVTHEAFDGYFGEDTDTADQLDRRLSDPSSGLDKPAAIIVETVQGEGGLNVASDAWLRKIEKIARKHGAL
FIIDDIQAGIGRTGGFFSFEKAGVTPDIITMAKSLSGLGLPFALTLIRPQHDLWKPGEHNGTFRGNNHAFVTATKALELF
WADDAFEKETARKAARLRAGLEKIAASASFAGRLKGKGMMSGIEMESGDVAAEICTECFQNGLIIETSGSMDEVVKVLAP
LTITDAELDAGLKILADAVRAVSARRQKSAA

Sequences:

>Translated_431_residues
MAYEHASAPANIFERRESRVRSYCRSFPAVFKSARGSELIAEDGTRYIDFLSGCSTLNYGHNHPELKQALLDYIGADGVA
HGLDMHTRAKARFLNTFERLILKPRSMDHRVLFPGPTGANAVEAALKTARKVTGRTNVIAFTNGFHGMTLGALAATGNSG
KRGGAGVPLTGVTHEAFDGYFGEDTDTADQLDRRLSDPSSGLDKPAAIIVETVQGEGGLNVASDAWLRKIEKIARKHGAL
FIIDDIQAGIGRTGGFFSFEKAGVTPDIITMAKSLSGLGLPFALTLIRPQHDLWKPGEHNGTFRGNNHAFVTATKALELF
WADDAFEKETARKAARLRAGLEKIAASASFAGRLKGKGMMSGIEMESGDVAAEICTECFQNGLIIETSGSMDEVVKVLAP
LTITDAELDAGLKILADAVRAVSARRQKSAA
>Mature_430_residues
AYEHASAPANIFERRESRVRSYCRSFPAVFKSARGSELIAEDGTRYIDFLSGCSTLNYGHNHPELKQALLDYIGADGVAH
GLDMHTRAKARFLNTFERLILKPRSMDHRVLFPGPTGANAVEAALKTARKVTGRTNVIAFTNGFHGMTLGALAATGNSGK
RGGAGVPLTGVTHEAFDGYFGEDTDTADQLDRRLSDPSSGLDKPAAIIVETVQGEGGLNVASDAWLRKIEKIARKHGALF
IIDDIQAGIGRTGGFFSFEKAGVTPDIITMAKSLSGLGLPFALTLIRPQHDLWKPGEHNGTFRGNNHAFVTATKALELFW
ADDAFEKETARKAARLRAGLEKIAASASFAGRLKGKGMMSGIEMESGDVAAEICTECFQNGLIIETSGSMDEVVKVLAPL
TITDAELDAGLKILADAVRAVSARRQKSAA

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=421, Percent_Identity=29.6912114014252, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=25.2821670428894, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI284507298, Length=314, Percent_Identity=29.6178343949045, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI188536080, Length=449, Percent_Identity=23.3853006681514, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI38679950, Length=449, Percent_Identity=23.3853006681514, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI38679946, Length=449, Percent_Identity=23.3853006681514, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI37574042, Length=438, Percent_Identity=23.2876712328767, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI24119277, Length=458, Percent_Identity=23.3624454148472, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI226442705, Length=395, Percent_Identity=24.5569620253165, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI226442709, Length=339, Percent_Identity=25.0737463126844, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1789016, Length=420, Percent_Identity=31.6666666666667, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1787560, Length=407, Percent_Identity=33.6609336609337, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1788044, Length=409, Percent_Identity=30.8068459657702, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789759, Length=406, Percent_Identity=28.5714285714286, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI145693181, Length=395, Percent_Identity=28.1012658227848, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786991, Length=424, Percent_Identity=27.5943396226415, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786349, Length=272, Percent_Identity=26.8382352941176, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25144271, Length=421, Percent_Identity=25.8907363420428, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI32564660, Length=420, Percent_Identity=30, Blast_Score=134, Evalue=9e-32,
Organism=Caenorhabditis elegans, GI25144274, Length=286, Percent_Identity=25.8741258741259, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17541228, Length=449, Percent_Identity=22.271714922049, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71992977, Length=440, Percent_Identity=21.5909090909091, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323470, Length=422, Percent_Identity=29.3838862559242, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6324432, Length=427, Percent_Identity=29.03981264637, Blast_Score=147, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321456, Length=447, Percent_Identity=23.9373601789709, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357415, Length=403, Percent_Identity=27.7915632754342, Blast_Score=148, Evalue=6e-36,
Organism=Drosophila melanogaster, GI28574759, Length=460, Percent_Identity=25.2173913043478, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI161085790, Length=470, Percent_Identity=24.468085106383, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21356575, Length=436, Percent_Identity=23.1651376146789, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46181; Mature: 46050

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYEHASAPANIFERRESRVRSYCRSFPAVFKSARGSELIAEDGTRYIDFLSGCSTLNYG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHCCCCCCCC
HNHPELKQALLDYIGADGVAHGLDMHTRAKARFLNTFERLILKPRSMDHRVLFPGPTGAN
CCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCH
AVEAALKTARKVTGRTNVIAFTNGFHGMTLGALAATGNSGKRGGAGVPLTGVTHEAFDGY
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHEECCCCCCCCCCCCCCCCCCHHHHCCC
FGEDTDTADQLDRRLSDPSSGLDKPAAIIVETVQGEGGLNVASDAWLRKIEKIARKHGAL
CCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCE
FIIDDIQAGIGRTGGFFSFEKAGVTPDIITMAKSLSGLGLPFALTLIRPQHDLWKPGEHN
EEEECCHHCCCCCCCCCEEHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
GTFRGNNHAFVTATKALELFWADDAFEKETARKAARLRAGLEKIAASASFAGRLKGKGMM
CCEECCCEEEEEEEHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGIEMESGDVAAEICTECFQNGLIIETSGSMDEVVKVLAPLTITDAELDAGLKILADAVR
CCCCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCEEECHHHHHHHHHHHHHHH
AVSARRQKSAA
HHHHHHHHCCC
>Mature Secondary Structure 
AYEHASAPANIFERRESRVRSYCRSFPAVFKSARGSELIAEDGTRYIDFLSGCSTLNYG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHCCCCCCCC
HNHPELKQALLDYIGADGVAHGLDMHTRAKARFLNTFERLILKPRSMDHRVLFPGPTGAN
CCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCH
AVEAALKTARKVTGRTNVIAFTNGFHGMTLGALAATGNSGKRGGAGVPLTGVTHEAFDGY
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHEECCCCCCCCCCCCCCCCCCHHHHCCC
FGEDTDTADQLDRRLSDPSSGLDKPAAIIVETVQGEGGLNVASDAWLRKIEKIARKHGAL
CCCCCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCE
FIIDDIQAGIGRTGGFFSFEKAGVTPDIITMAKSLSGLGLPFALTLIRPQHDLWKPGEHN
EEEECCHHCCCCCCCCCEEHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCC
GTFRGNNHAFVTATKALELFWADDAFEKETARKAARLRAGLEKIAASASFAGRLKGKGMM
CCEECCCEEEEEEEHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGIEMESGDVAAEICTECFQNGLIIETSGSMDEVVKVLAPLTITDAELDAGLKILADAVR
CCCCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCEEECHHHHHHHHHHHHHHH
AVSARRQKSAA
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]