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The map label for this gene is ectC

Identifier: 114799353

GI number: 114799353

Start: 1678102

End: 1678509

Strand: Direct

Name: ectC

Synonym: HNE_1641

Alternate gene names: 114799353

Gene position: 1678102-1678509 (Clockwise)

Preceding gene: 114799897

Following gene: 114798545

Centisome position: 45.29

GC content: 57.35

Gene sequence:

>408_bases
ATGATTGTTAGAGACCTCGCAAAAGAAATCCTTACAGACCGCCGCGTGGACAGCGACGGCTGGTCTTCCGTTCGCCTGCT
GCTGAAAGATGATGGAATGGGTTTCTCCTTCCACATCACCACGATCCATGCCGGCGCCGAGCTGCACATGCATTACAAGA
ACCACCTTGAGAGTGTGTTCTGCATGGAAGGCACAGGCTCCATCACCGATCTGGCGACAGGCGAAACGCACGAAATCCGT
CCGGGCGTAATGTACGCGCTCAACAAGAACGACAAGCATATCCTGCGCGCGAATGCCGGGGCCCCAATGATGATGGCCTG
TGTGTTCAATCCGCCAGTGACAGGCAAGGAAGTGCACGGCGAGGACGGGGCCTACCCCGCAGACGCCGCACTCGAAAACT
CTGCCTGA

Upstream 100 bases:

>100_bases
TCACCGATGCCGAATTGGATGCCGGCCTCAAAATTCTTGCGGACGCCGTGCGCGCGGTCAGCGCGCGCCGCCAGAAGTCC
GCAGCCTGAAGGAGATAAAA

Downstream 100 bases:

>100_bases
AGGGAGAGACTCCATGATGACGCAAACAGAACAAGACCTTTACCCATCGCGGCAAAGGGCAGAGCCGGAATGGCTTGAAC
GTAGAGACCCCGTGGTTCAT

Product: L-ectoine synthase

Products: NA

Alternate protein names: N-acetyldiaminobutyrate dehydratase

Number of amino acids: Translated: 135; Mature: 135

Protein sequence:

>135_residues
MIVRDLAKEILTDRRVDSDGWSSVRLLLKDDGMGFSFHITTIHAGAELHMHYKNHLESVFCMEGTGSITDLATGETHEIR
PGVMYALNKNDKHILRANAGAPMMMACVFNPPVTGKEVHGEDGAYPADAALENSA

Sequences:

>Translated_135_residues
MIVRDLAKEILTDRRVDSDGWSSVRLLLKDDGMGFSFHITTIHAGAELHMHYKNHLESVFCMEGTGSITDLATGETHEIR
PGVMYALNKNDKHILRANAGAPMMMACVFNPPVTGKEVHGEDGAYPADAALENSA
>Mature_135_residues
MIVRDLAKEILTDRRVDSDGWSSVRLLLKDDGMGFSFHITTIHAGAELHMHYKNHLESVFCMEGTGSITDLATGETHEIR
PGVMYALNKNDKHILRANAGAPMMMACVFNPPVTGKEVHGEDGAYPADAALENSA

Specific function: Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ectoine synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ECTC_HYPNA (Q0C1P4)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760349.1
- ProteinModelPortal:   Q0C1P4
- STRING:   Q0C1P4
- GeneID:   4288123
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1641
- NMPDR:   fig|228405.5.peg.1586
- TIGR:   HNE_1641
- eggNOG:   NOG08290
- HOGENOM:   HBG294526
- OMA:   DENGVYP
- ProtClustDB:   PRK13290
- BioCyc:   HNEP81032:HNE_1641-MONOMER
- HAMAP:   MF_01255
- InterPro:   IPR011051
- InterPro:   IPR010462
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- ProDom:   PD080544

Pfam domain/function: PF06339 Ectoine_synth; SSF51182 RmlC_like_cupin

EC number: =4.2.1.108

Molecular weight: Translated: 14753; Mature: 14753

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRDLAKEILTDRRVDSDGWSSVRLLLKDDGMGFSFHITTIHAGAELHMHYKNHLESVF
CCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCEEEEEHHHCCCEEE
CMEGTGSITDLATGETHEIRPGVMYALNKNDKHILRANAGAPMMMACVFNPPVTGKEVHG
EECCCCCEEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEEEECCCCCCCEECC
EDGAYPADAALENSA
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MIVRDLAKEILTDRRVDSDGWSSVRLLLKDDGMGFSFHITTIHAGAELHMHYKNHLESVF
CCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCEEEEEHHHCCCEEE
CMEGTGSITDLATGETHEIRPGVMYALNKNDKHILRANAGAPMMMACVFNPPVTGKEVHG
EECCCCCEEECCCCCCCCCCCCEEEEECCCCCEEEEECCCCCEEEEEEECCCCCCCEECC
EDGAYPADAALENSA
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA