Click here to switch to the map view.

The map label for this gene is kdtA [H]

Identifier: 114799880

GI number: 114799880

Start: 712801

End: 714090

Strand: Reverse

Name: kdtA [H]

Synonym: HNE_0701

Alternate gene names: 114799880

Gene position: 714090-712801 (Counterclockwise)

Preceding gene: 114797159

Following gene: 114799558

Centisome position: 19.27

GC content: 68.6

Gene sequence:

>1290_bases
ATGACGCCCGCGTTGTTCGCCTACCGGCTCGCCACCTATGCGGCGTCGCCCTTCCTGGGTTTCCTGCTGAGCCAGCGGGC
CAAAGAGGGCAAGGAAGACTATCTGCGCCTGCATGAGCGCTATGCCAAACGCCTGCCGCCCCGCCGCCCCGGCCCGCTGA
TCTGGCTGCATGGCGCCAGTGTCGGCGAAAGCGGCCTGCTGCTGGAACTCGGCCGCCGCCTGATTGCGGCCCGCCCCGGC
GTGATGCTGGTCTTCACCAGCCAGACCCAGACCTCCGCCCGCCTCCTCGGCCCGCTCCTGCCGGATAATGCCATCCACGC
CATGGCCCCGCTCGATACGCCCCAGGCCGCCCGCCGCTTCATCCAGCACTGGAAGCCCGATCTCTGCGTCTTCGCCGAAG
GCGAGATCTGGCCCAACCTGATCCATGAAGCCCGCAAGAGCGGCGCACGCACGGCGCTGGTCAATGCGCGGATGACCCAG
AAATCGGCCGAAGGCTGGCAGAGGGTGCGCGGCCTCTTCCAACAGCTCGTCGGCCGGTTCGACATTGTCCTGGCCGCAGA
CCTCGATACCGGCCAGCGCCTGGAAGGCCTGCTCGGCCGGCCGGTGCGCGCCGCCGGCAATCTCAAATCTGCCCTGCCGC
CACCTGCCGCCAACGAGGTGGAGCTGACCCGCATCGCGGGCAATTTCATCGCCGGGCGCCGCTGCCTGCTGGCCGCGTCC
ACGCATGCCGGTGAGGAGGAAATCTTCCTCGATGCTGCCGCCGCGCTGGACGAAGACATCGCCCTCATCATCGCCCCGCG
CCATCCAGATCGCGGTGAGGAAATCGAAGCGCTGCTGAAACAGCGCGGCCTGCGCCATGCGCGCCGCTCCAAAGGCGTGC
AGCCCGACAAGCGCGACCGCGTTCTGCTCGCCGACACGATGGGCGAAATGGGCCTCTGGATGCGCCTTGCGAACGCCGTC
TATCTTGGCGGCGGCCATACTGAAGGTGTCGGCGGGCATAATCCGCTTGAACCCATCCGTCTCAACCGCCCGGTCGCCAC
CGGCCCGCATGTCCACAACTTTGCAGACCTGATGGCGAGCCTTGCAGCCAGCGGCCTCGTGCACACTGTTGCCGATGCCG
GCGCCCTCACAGCTTTCCTGCGCCAGCCGTCTGCTGTGCCCGAAGACGCCCTTGCCGCCCTGACGGCGGAGGCCGACGAG
CCGATGCTGCTCACGCTGGGCGCGCTGCTGCCCCTCCTGCCCCAACCCCTGCTGGAGGGCAGCGACGGCGACTGGGAGCG
CCAGCGGTGA

Upstream 100 bases:

>100_bases
TGCAAGACGCGCTGCAACGCGGCATGGATGAGGCAACCCGGCGTGCCGAAAGTCTCGCCGGCCACCCCGTTCAACCTGCA
AGGCCGGAGCTTACCCCTGA

Downstream 100 bases:

>100_bases
AGGCGCCGTATTTCTGGTCGGCGGATCTCGATCCGAAATCCCGCGAAGCGGCCCCGCTGACCCGTCTGCTGCTGACGCCC
TTCGCAATGCTCTATCTCTG

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MTPALFAYRLATYAASPFLGFLLSQRAKEGKEDYLRLHERYAKRLPPRRPGPLIWLHGASVGESGLLLELGRRLIAARPG
VMLVFTSQTQTSARLLGPLLPDNAIHAMAPLDTPQAARRFIQHWKPDLCVFAEGEIWPNLIHEARKSGARTALVNARMTQ
KSAEGWQRVRGLFQQLVGRFDIVLAADLDTGQRLEGLLGRPVRAAGNLKSALPPPAANEVELTRIAGNFIAGRRCLLAAS
THAGEEEIFLDAAAALDEDIALIIAPRHPDRGEEIEALLKQRGLRHARRSKGVQPDKRDRVLLADTMGEMGLWMRLANAV
YLGGGHTEGVGGHNPLEPIRLNRPVATGPHVHNFADLMASLAASGLVHTVADAGALTAFLRQPSAVPEDALAALTAEADE
PMLLTLGALLPLLPQPLLEGSDGDWERQR

Sequences:

>Translated_429_residues
MTPALFAYRLATYAASPFLGFLLSQRAKEGKEDYLRLHERYAKRLPPRRPGPLIWLHGASVGESGLLLELGRRLIAARPG
VMLVFTSQTQTSARLLGPLLPDNAIHAMAPLDTPQAARRFIQHWKPDLCVFAEGEIWPNLIHEARKSGARTALVNARMTQ
KSAEGWQRVRGLFQQLVGRFDIVLAADLDTGQRLEGLLGRPVRAAGNLKSALPPPAANEVELTRIAGNFIAGRRCLLAAS
THAGEEEIFLDAAAALDEDIALIIAPRHPDRGEEIEALLKQRGLRHARRSKGVQPDKRDRVLLADTMGEMGLWMRLANAV
YLGGGHTEGVGGHNPLEPIRLNRPVATGPHVHNFADLMASLAASGLVHTVADAGALTAFLRQPSAVPEDALAALTAEADE
PMLLTLGALLPLLPQPLLEGSDGDWERQR
>Mature_428_residues
TPALFAYRLATYAASPFLGFLLSQRAKEGKEDYLRLHERYAKRLPPRRPGPLIWLHGASVGESGLLLELGRRLIAARPGV
MLVFTSQTQTSARLLGPLLPDNAIHAMAPLDTPQAARRFIQHWKPDLCVFAEGEIWPNLIHEARKSGARTALVNARMTQK
SAEGWQRVRGLFQQLVGRFDIVLAADLDTGQRLEGLLGRPVRAAGNLKSALPPPAANEVELTRIAGNFIAGRRCLLAAST
HAGEEEIFLDAAAALDEDIALIIAPRHPDRGEEIEALLKQRGLRHARRSKGVQPDKRDRVLLADTMGEMGLWMRLANAVY
LGGGHTEGVGGHNPLEPIRLNRPVATGPHVHNFADLMASLAASGLVHTVADAGALTAFLRQPSAVPEDALAALTAEADEP
MLLTLGALLPLLPQPLLEGSDGDWERQR

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA) [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=392, Percent_Identity=33.6734693877551, Blast_Score=177, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007507 [H]

Pfam domain/function: PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 46591; Mature: 46460

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPALFAYRLATYAASPFLGFLLSQRAKEGKEDYLRLHERYAKRLPPRRPGPLIWLHGAS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
VGESGLLLELGRRLIAARPGVMLVFTSQTQTSARLLGPLLPDNAIHAMAPLDTPQAARRF
CCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
IQHWKPDLCVFAEGEIWPNLIHEARKSGARTALVNARMTQKSAEGWQRVRGLFQQLVGRF
HHHCCCCEEEEECCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHE
DIVLAADLDTGQRLEGLLGRPVRAAGNLKSALPPPAANEVELTRIAGNFIAGRRCLLAAS
EEEEEECCCCCHHHHHHHCCCCHHCCCCCCCCCCCCCCCEEEHHHHHHHHHCCEEEEEEC
THAGEEEIFLDAAAALDEDIALIIAPRHPDRGEEIEALLKQRGLRHARRSKGVQPDKRDR
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VLLADTMGEMGLWMRLANAVYLGGGHTEGVGGHNPLEPIRLNRPVATGPHVHNFADLMAS
EEEEHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHH
LAASGLVHTVADAGALTAFLRQPSAVPEDALAALTAEADEPMLLTLGALLPLLPQPLLEG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCC
SDGDWERQR
CCCCCCCCC
>Mature Secondary Structure 
TPALFAYRLATYAASPFLGFLLSQRAKEGKEDYLRLHERYAKRLPPRRPGPLIWLHGAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCC
VGESGLLLELGRRLIAARPGVMLVFTSQTQTSARLLGPLLPDNAIHAMAPLDTPQAARRF
CCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
IQHWKPDLCVFAEGEIWPNLIHEARKSGARTALVNARMTQKSAEGWQRVRGLFQQLVGRF
HHHCCCCEEEEECCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHE
DIVLAADLDTGQRLEGLLGRPVRAAGNLKSALPPPAANEVELTRIAGNFIAGRRCLLAAS
EEEEEECCCCCHHHHHHHCCCCHHCCCCCCCCCCCCCCCEEEHHHHHHHHHCCEEEEEEC
THAGEEEIFLDAAAALDEDIALIIAPRHPDRGEEIEALLKQRGLRHARRSKGVQPDKRDR
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
VLLADTMGEMGLWMRLANAVYLGGGHTEGVGGHNPLEPIRLNRPVATGPHVHNFADLMAS
EEEEHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHH
LAASGLVHTVADAGALTAFLRQPSAVPEDALAALTAEADEPMLLTLGALLPLLPQPLLEG
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHCC
SDGDWERQR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA