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The map label for this gene is aceE [H]

Identifier: 114799863

GI number: 114799863

Start: 3154082

End: 3156466

Strand: Direct

Name: aceE [H]

Synonym: HNE_2995

Alternate gene names: 114799863

Gene position: 3154082-3156466 (Clockwise)

Preceding gene: 114798774

Following gene: 114797530

Centisome position: 85.13

GC content: 63.14

Gene sequence:

>2385_bases
ATGCCTCTTTCTTTCAAACAGCTGAAAACCATTGAGCAGCGCCTCCTCTGGCTGGCCGCCTGGACGGTTCACAATGCCAA
CCATCTTCGCGAGAAGGCGGACGATGATGTGAAGGTGGGCGGGCATCAGGCGAGCTGCGCATCGATTGTGTCGATCATGA
CGGCGCTCTATTTCCATGTGCTGCGGCCCGAAGACCGGGTGGCGGTTAAGCCCCATGCCGCGCCGGTGTTCCATGCGATG
CATTACCTGATGGGCAGCCAGACGCGCGAGAAGCTGGAAAATTTCCGGGGCTATGGCGGGGCGCAGTCCTATCCCTCGCG
CACCAAGGATATTGATGACGTGGATTTCTCCACCGGATCGGTTGGCCTGGGTGTAGCGGAGACAGCTTTTGCCTCGATCA
TTCAGGACTACCTGATTGCCCGTCCGTGGACGGATTTTGGCTCGGGCAAACGCCCCGCCGGCCGGATGGTGGCGCTGGTG
GGTGACGCTGAGCTGGACGAGGGCAATGTGTATGAATGCCTTCAGGAAGGCTGGAAGCATGGCCTGCGCAATACCTGGTG
GATCATCGACTATAACCGGCAGAGCCTCGACGGCGTGGTACATGAAGGGCTCTGGACGAAGATCGAGGCGATCTTCAAGG
CGTTTGGCTGGCGCGTAGAGGTGTTGCGCTTTGGCGCGTTGCAGCGGGCCGCCTTTGCAGAACCGGGCGGCGAGCGCCTG
AAACAGTGGATCGAGGACTGCCCCAATCCGCTCTATTCGGCCCTCACCTATATGGGCGGCGCGGCATGGCGCAAGCGTCT
GCTGGACGACATTGGCGATCAGGGCGACGTGGCCGCCTTGCTCGAGAAGCGCTCGGATACGCAGCTCAGTGAACTGATGA
ACAATCTGGGCGGGCAATGCCTGGAGACGTTGCTGGAGGCCTTCTCCCGCGCCGATGACGAGCGGCCAACGGTGTTCCTC
GCCTATACGATCAAGGGATGGAGCACGCCGCTTGCGGGGCATAAGGACAACCATGCCGGCCTGATGACCAAGGCACAGAT
GGCCGATTTCCAGAAGGTGATGGGCGTCGCCGAGGGAGAGGAATGGGAGCCGTTTGCGACGGTGAAACAGCCCGGCGATC
TGCAAGCGGCGCTGGAGGATGTTGCGTTCTTCGCCAAGGGTGCCCGCCGTTACAGTGCGCCGCGGGTGCCCTCCCCCGGA
CCGGTGTTTCTGGAAGACGAGACGCTTTCCACGCAGGCCGGGCTTGGCAAGATCCTCGACAGCCTGGCGCGCGGCGATAC
GGAGCTGGCGCAGCGTATACTGACGACATCGCCGGATGTGACGGTGTCGACCAATCTGGGCGGCTGGGTGAACCGGCGCG
GCCTGTTTGCGCGGGAGGCTGTGGCCGACACGTTCCGGGACCAGAAAATCCCCTCGGCGCAAAAATGGGCATTCTCTCCT
GAGGGGCAGCATATCGAGCTGGGCATTGCGGAGATGAACCTGTTCCTGCTGCTGGGCGCAGCGGGGCTTTCCCATTCTCT
CTTTGGCGAGCGGCTGATCCCGGTCGGGACGGTGTATGATCCGTTTGTGGCGCGGGGCCTCGATGCGCTGAATTATGCCT
GTTATCAGGATGCGCGCTTCATTATTGCGGGCACGCCTTCGGGCGTGACGCTGGCCCCGGAGGGCGGCGCACACCAGTCC
ATCGGCGCGCAGCTGATCGGGATGAGCCAGGACGGCATCGTTTCCTTCGAACCGGCATTTCTGGACGAGCTGTCGATCAT
CATGGACTGGTCGTTCGACTATCTGCAGCGCGACGGCGAGGGCGACCCGGACGAGCGCACCTGGCTGCGTGACGAGACGG
GTGGATCGGTTTACCTGCGGCTTTCAACCCGGCCTGTTGAGCAGGTGCGCGCCTGGTCACGCGAAGACGCTGCGTTCCGG
CAGGGCGTGATTGATGGCGGCTACTGGCTACGCAAGCCGGGCCCGAACGCCGAAGTCATCATTGCCTATCAGGGCGTGAT
AGCGCCCGAAGCGATCAAGGCAGCCGCGCGGATCGGCGAAGGGCGGCGCGACATTGGCGTTCTGGCGGTCACATCAGCCG
ACCGGTTGAATTCCGGCTGGACGGCGGCGCGCCGAGCACGGGCGCGCGGGCAGAAGACCGCCATCAGCCAGATTGAGCGG
TTGATGGACGGTGTGCCCCGGCACGCGCAGCTGATCACGGTGACGGATGGGCATCCGGCAACACTCGCCTGGATCGGCGG
CGTAAAGGGCCATCCGGTGACCCCGCTGGGCGTCGAGCATTTTGGACAGACCGGCACGATCCGGGACCTCTACCGGCACT
TCATGATTGACGCTGATGCTATCGTCTCCGCGGCCAGCCACCTGTCTCCGGGTAAAAGCCTCTAG

Upstream 100 bases:

>100_bases
TCCAAGGGGCTGGTTTTGTTGCCGGGTTGGCCATGGACTTGCCCGAGCGTCTGATCTAGGCGGTAGGAATTGCCCTTCCC
TAGCGATATGGCCGAATTCC

Downstream 100 bases:

>100_bases
CCCGGGCCGTTTGCCGGATCTGTAGTAGGTGGTGCAGCTGCGCTGAGTATAAGTGCCGATAAGGCGGAGAATTCCCGCAT
TAAAACAACGTGATCTTTAC

Product: pyruvate dehydrogenase E1 component-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 793

Protein sequence:

>794_residues
MPLSFKQLKTIEQRLLWLAAWTVHNANHLREKADDDVKVGGHQASCASIVSIMTALYFHVLRPEDRVAVKPHAAPVFHAM
HYLMGSQTREKLENFRGYGGAQSYPSRTKDIDDVDFSTGSVGLGVAETAFASIIQDYLIARPWTDFGSGKRPAGRMVALV
GDAELDEGNVYECLQEGWKHGLRNTWWIIDYNRQSLDGVVHEGLWTKIEAIFKAFGWRVEVLRFGALQRAAFAEPGGERL
KQWIEDCPNPLYSALTYMGGAAWRKRLLDDIGDQGDVAALLEKRSDTQLSELMNNLGGQCLETLLEAFSRADDERPTVFL
AYTIKGWSTPLAGHKDNHAGLMTKAQMADFQKVMGVAEGEEWEPFATVKQPGDLQAALEDVAFFAKGARRYSAPRVPSPG
PVFLEDETLSTQAGLGKILDSLARGDTELAQRILTTSPDVTVSTNLGGWVNRRGLFAREAVADTFRDQKIPSAQKWAFSP
EGQHIELGIAEMNLFLLLGAAGLSHSLFGERLIPVGTVYDPFVARGLDALNYACYQDARFIIAGTPSGVTLAPEGGAHQS
IGAQLIGMSQDGIVSFEPAFLDELSIIMDWSFDYLQRDGEGDPDERTWLRDETGGSVYLRLSTRPVEQVRAWSREDAAFR
QGVIDGGYWLRKPGPNAEVIIAYQGVIAPEAIKAAARIGEGRRDIGVLAVTSADRLNSGWTAARRARARGQKTAISQIER
LMDGVPRHAQLITVTDGHPATLAWIGGVKGHPVTPLGVEHFGQTGTIRDLYRHFMIDADAIVSAASHLSPGKSL

Sequences:

>Translated_794_residues
MPLSFKQLKTIEQRLLWLAAWTVHNANHLREKADDDVKVGGHQASCASIVSIMTALYFHVLRPEDRVAVKPHAAPVFHAM
HYLMGSQTREKLENFRGYGGAQSYPSRTKDIDDVDFSTGSVGLGVAETAFASIIQDYLIARPWTDFGSGKRPAGRMVALV
GDAELDEGNVYECLQEGWKHGLRNTWWIIDYNRQSLDGVVHEGLWTKIEAIFKAFGWRVEVLRFGALQRAAFAEPGGERL
KQWIEDCPNPLYSALTYMGGAAWRKRLLDDIGDQGDVAALLEKRSDTQLSELMNNLGGQCLETLLEAFSRADDERPTVFL
AYTIKGWSTPLAGHKDNHAGLMTKAQMADFQKVMGVAEGEEWEPFATVKQPGDLQAALEDVAFFAKGARRYSAPRVPSPG
PVFLEDETLSTQAGLGKILDSLARGDTELAQRILTTSPDVTVSTNLGGWVNRRGLFAREAVADTFRDQKIPSAQKWAFSP
EGQHIELGIAEMNLFLLLGAAGLSHSLFGERLIPVGTVYDPFVARGLDALNYACYQDARFIIAGTPSGVTLAPEGGAHQS
IGAQLIGMSQDGIVSFEPAFLDELSIIMDWSFDYLQRDGEGDPDERTWLRDETGGSVYLRLSTRPVEQVRAWSREDAAFR
QGVIDGGYWLRKPGPNAEVIIAYQGVIAPEAIKAAARIGEGRRDIGVLAVTSADRLNSGWTAARRARARGQKTAISQIER
LMDGVPRHAQLITVTDGHPATLAWIGGVKGHPVTPLGVEHFGQTGTIRDLYRHFMIDADAIVSAASHLSPGKSL
>Mature_793_residues
PLSFKQLKTIEQRLLWLAAWTVHNANHLREKADDDVKVGGHQASCASIVSIMTALYFHVLRPEDRVAVKPHAAPVFHAMH
YLMGSQTREKLENFRGYGGAQSYPSRTKDIDDVDFSTGSVGLGVAETAFASIIQDYLIARPWTDFGSGKRPAGRMVALVG
DAELDEGNVYECLQEGWKHGLRNTWWIIDYNRQSLDGVVHEGLWTKIEAIFKAFGWRVEVLRFGALQRAAFAEPGGERLK
QWIEDCPNPLYSALTYMGGAAWRKRLLDDIGDQGDVAALLEKRSDTQLSELMNNLGGQCLETLLEAFSRADDERPTVFLA
YTIKGWSTPLAGHKDNHAGLMTKAQMADFQKVMGVAEGEEWEPFATVKQPGDLQAALEDVAFFAKGARRYSAPRVPSPGP
VFLEDETLSTQAGLGKILDSLARGDTELAQRILTTSPDVTVSTNLGGWVNRRGLFAREAVADTFRDQKIPSAQKWAFSPE
GQHIELGIAEMNLFLLLGAAGLSHSLFGERLIPVGTVYDPFVARGLDALNYACYQDARFIIAGTPSGVTLAPEGGAHQSI
GAQLIGMSQDGIVSFEPAFLDELSIIMDWSFDYLQRDGEGDPDERTWLRDETGGSVYLRLSTRPVEQVRAWSREDAAFRQ
GVIDGGYWLRKPGPNAEVIIAYQGVIAPEAIKAAARIGEGRRDIGVLAVTSADRLNSGWTAARRARARGQKTAISQIERL
MDGVPRHAQLITVTDGHPATLAWIGGVKGHPVTPLGVEHFGQTGTIRDLYRHFMIDADAIVSAASHLSPGKSL

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=829, Percent_Identity=23.8841978287093, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 87093; Mature: 86962

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00422 GRANINS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSFKQLKTIEQRLLWLAAWTVHNANHLREKADDDVKVGGHQASCASIVSIMTALYFHV
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHH
LRPEDRVAVKPHAAPVFHAMHYLMGSQTREKLENFRGYGGAQSYPSRTKDIDDVDFSTGS
CCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
VGLGVAETAFASIIQDYLIARPWTDFGSGKRPAGRMVALVGDAELDEGNVYECLQEGWKH
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
GLRNTWWIIDYNRQSLDGVVHEGLWTKIEAIFKAFGWRVEVLRFGALQRAAFAEPGGERL
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
KQWIEDCPNPLYSALTYMGGAAWRKRLLDDIGDQGDVAALLEKRSDTQLSELMNNLGGQC
HHHHHHCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCHHH
LETLLEAFSRADDERPTVFLAYTIKGWSTPLAGHKDNHAGLMTKAQMADFQKVMGVAEGE
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
EWEPFATVKQPGDLQAALEDVAFFAKGARRYSAPRVPSPGPVFLEDETLSTQAGLGKILD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
SLARGDTELAQRILTTSPDVTVSTNLGGWVNRRGLFAREAVADTFRDQKIPSAQKWAFSP
HHHCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
EGQHIELGIAEMNLFLLLGAAGLSHSLFGERLIPVGTVYDPFVARGLDALNYACYQDARF
CCCEEEEEHHHHEEEHHEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
IIAGTPSGVTLAPEGGAHQSIGAQLIGMSQDGIVSFEPAFLDELSIIMDWSFDYLQRDGE
EEEECCCCCEECCCCCCCCCCCCEEECCCCCCCEEECHHHHHHHHHHHCCCHHHHHCCCC
GDPDERTWLRDETGGSVYLRLSTRPVEQVRAWSREDAAFRQGVIDGGYWLRKPGPNAEVI
CCCCHHCEEECCCCCEEEEEECCCCHHHHHHCCHHHHHHHHCCCCCCEEECCCCCCCEEE
IAYQGVIAPEAIKAAARIGEGRRDIGVLAVTSADRLNSGWTAARRARARGQKTAISQIER
EEECCCCCHHHHHHHHHHCCCCCCEEEEEEECHHHCCCCHHHHHHHHHCCHHHHHHHHHH
LMDGVPRHAQLITVTDGHPATLAWIGGVKGHPVTPLGVEHFGQTGTIRDLYRHFMIDADA
HHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHCCHHH
IVSAASHLSPGKSL
HHHHHHHCCCCCCC
>Mature Secondary Structure 
PLSFKQLKTIEQRLLWLAAWTVHNANHLREKADDDVKVGGHQASCASIVSIMTALYFHV
CCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHH
LRPEDRVAVKPHAAPVFHAMHYLMGSQTREKLENFRGYGGAQSYPSRTKDIDDVDFSTGS
CCCCCCEEECCCCHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
VGLGVAETAFASIIQDYLIARPWTDFGSGKRPAGRMVALVGDAELDEGNVYECLQEGWKH
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHH
GLRNTWWIIDYNRQSLDGVVHEGLWTKIEAIFKAFGWRVEVLRFGALQRAAFAEPGGERL
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
KQWIEDCPNPLYSALTYMGGAAWRKRLLDDIGDQGDVAALLEKRSDTQLSELMNNLGGQC
HHHHHHCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCHHH
LETLLEAFSRADDERPTVFLAYTIKGWSTPLAGHKDNHAGLMTKAQMADFQKVMGVAEGE
HHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
EWEPFATVKQPGDLQAALEDVAFFAKGARRYSAPRVPSPGPVFLEDETLSTQAGLGKILD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHH
SLARGDTELAQRILTTSPDVTVSTNLGGWVNRRGLFAREAVADTFRDQKIPSAQKWAFSP
HHHCCCHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
EGQHIELGIAEMNLFLLLGAAGLSHSLFGERLIPVGTVYDPFVARGLDALNYACYQDARF
CCCEEEEEHHHHEEEHHEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEE
IIAGTPSGVTLAPEGGAHQSIGAQLIGMSQDGIVSFEPAFLDELSIIMDWSFDYLQRDGE
EEEECCCCCEECCCCCCCCCCCCEEECCCCCCCEEECHHHHHHHHHHHCCCHHHHHCCCC
GDPDERTWLRDETGGSVYLRLSTRPVEQVRAWSREDAAFRQGVIDGGYWLRKPGPNAEVI
CCCCHHCEEECCCCCEEEEEECCCCHHHHHHCCHHHHHHHHCCCCCCEEECCCCCCCEEE
IAYQGVIAPEAIKAAARIGEGRRDIGVLAVTSADRLNSGWTAARRARARGQKTAISQIER
EEECCCCCHHHHHHHHHHCCCCCCEEEEEEECHHHCCCCHHHHHHHHHCCHHHHHHHHHH
LMDGVPRHAQLITVTDGHPATLAWIGGVKGHPVTPLGVEHFGQTGTIRDLYRHFMIDADA
HHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCHHHCCCCCCHHHHHHHHHCCHHH
IVSAASHLSPGKSL
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9171401; 10984043 [H]