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The map label for this gene is grxC2 [H]

Identifier: 114799856

GI number: 114799856

Start: 2019757

End: 2020092

Strand: Direct

Name: grxC2 [H]

Synonym: HNE_1949

Alternate gene names: 114799856

Gene position: 2019757-2020092 (Clockwise)

Preceding gene: 114799176

Following gene: 114797359

Centisome position: 54.51

GC content: 56.55

Gene sequence:

>336_bases
ATGACTGACCAGGCCACCCTCGACGCCATCGAAAAAGCCGTCAAAAGCAATGACGTTGTCCTCTTCATGAAGGGCACGCC
CACCTTCCCGCAATGCGGATTTTCCTCCACTGTGGTGCAGATCCTGGACTATCTGGGCGTCGAATATGTCGCCACCAACG
TGCTGGAAGACCAGAACGTCCGCGAAGGCATCAAGCAATACGCCAACTGGCCGACCATCCCCCAACTCTACGTGAAGGGC
GAATTCGTCGGCGGCTGCGACATCCTCAAAGAGATGTTCGAAAACGGCGAACTGCGCGACCTGATGGCCGAAAACGGCAT
CGAACTGGCCGAATAG

Upstream 100 bases:

>100_bases
ACCCGGATGGCGCCGCCAGTCCGGACACTGCCATATGGCGCGCCCTCTTGACCCTCACGCCTCGCCGCATCACATGTGCG
CTGAACGCGGAGACACCCCT

Downstream 100 bases:

>100_bases
GTCTCGCCCGTCCCGTTATGGCGGGAATTTATAGGGCCGCCTGACCTGCTTTTGTCAAAAGCTGCGCCTCTCCTTGTAGG
GTTACAAGGAGACCTTAGCG

Product: glutaredoxin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MTDQATLDAIEKAVKSNDVVLFMKGTPTFPQCGFSSTVVQILDYLGVEYVATNVLEDQNVREGIKQYANWPTIPQLYVKG
EFVGGCDILKEMFENGELRDLMAENGIELAE

Sequences:

>Translated_111_residues
MTDQATLDAIEKAVKSNDVVLFMKGTPTFPQCGFSSTVVQILDYLGVEYVATNVLEDQNVREGIKQYANWPTIPQLYVKG
EFVGGCDILKEMFENGELRDLMAENGIELAE
>Mature_110_residues
TDQATLDAIEKAVKSNDVVLFMKGTPTFPQCGFSSTVVQILDYLGVEYVATNVLEDQNVREGIKQYANWPTIPQLYVKGE
FVGGCDILKEMFENGELRDLMAENGIELAE

Specific function: Unknown

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI42516576, Length=105, Percent_Identity=58.0952380952381, Blast_Score=124, Evalue=2e-29,
Organism=Homo sapiens, GI95113651, Length=80, Percent_Identity=60, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787943, Length=101, Percent_Identity=43.5643564356436, Blast_Score=110, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17556042, Length=98, Percent_Identity=56.1224489795918, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71988153, Length=85, Percent_Identity=44.7058823529412, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71988159, Length=85, Percent_Identity=44.7058823529412, Blast_Score=97, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325198, Length=99, Percent_Identity=56.5656565656566, Blast_Score=121, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321022, Length=83, Percent_Identity=48.1927710843374, Blast_Score=95, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320303, Length=85, Percent_Identity=47.0588235294118, Blast_Score=92, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24642023, Length=105, Percent_Identity=51.4285714285714, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI19921242, Length=101, Percent_Identity=38.6138613861386, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 12354; Mature: 12223

Theoretical pI: Translated: 3.95; Mature: 3.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQATLDAIEKAVKSNDVVLFMKGTPTFPQCGFSSTVVQILDYLGVEYVATNVLEDQNV
CCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
REGIKQYANWPTIPQLYVKGEFVGGCDILKEMFENGELRDLMAENGIELAE
HHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDQATLDAIEKAVKSNDVVLFMKGTPTFPQCGFSSTVVQILDYLGVEYVATNVLEDQNV
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
REGIKQYANWPTIPQLYVKGEFVGGCDILKEMFENGELRDLMAENGIELAE
HHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA