Click here to switch to the map view.

The map label for this gene is 114799176

Identifier: 114799176

GI number: 114799176

Start: 2015958

End: 2017805

Strand: Direct

Name: 114799176

Synonym: HNE_1947

Alternate gene names: NA

Gene position: 2015958-2017805 (Clockwise)

Preceding gene: 114799421

Following gene: 114799856

Centisome position: 54.41

GC content: 62.45

Gene sequence:

>1848_bases
ATGATGCGTCACGTTTTCAAACCTGCCTTGAAGTCTGCCAGCCTGATCGCTATCGGGCTCGCCCTCGCCGCATGCGGCCC
GGCGAAAACAACGATCGACCCTGACGCCATCGCCATGGAAGAGCGCGCCATTGAAGCCCGCGCCTTCCTGGACGACGCGG
AAAGCCAGATCGCCGCCAAGAGCCACATCGCTGCCCAGGCCTATTGGGACCAGGCCACCAATATCACCCCGGAAACCAGC
GCGGCCGCTGCCCAGCAGGGCGCCGAATTCACCAAGCTGGTCGTAAGTCTCGCCAACGCCTCGAAAGACTTCGACGTGTC
AGAACTGCCACCCGCAGAAGCCCGCAAGCTTCAGATCCTGCGCAGCGGCATCACCCTGCCTGCCCCCTCCCGCGAAGGCG
CCGCCGAGGAACTGGCGGACATCACCACAAAGCTGGACGCCACCTACTCAACCGGCAAATTCATGTTCCAGGGCCGCGAG
ATCGACCTGCTGGAAGCCTCCCGCATCATCCAGGAATCGCGCGATCCCGAGGAATTGAAAGCCGTATGGGAAGGCTGGCA
TTCCATCGCCGCGCCCATGGCGCCCGATTACACCCGCATGGTGGAAATCGCCAATGAGGGCGCGCGCGAACTTGGCTATC
CCAGCCTCGACCAGATGTGGCTGTCCAACTACGACATGCCGCCCGCCCAGATGGAAGCCGAAGTCCAGCGCCTCTGGTCG
CAGGTAGAGCCGCTCTACAAGGAGCTGCACTGCTACACGCGCGGCCGCCTCAACTCCTATTATGGCGAGGCCGTCCAGCC
TGCCGCCGGCCCCATCCGGGCAGACCTGCTCGGTAATATGTGGGCCCAGCAATGGTCGGGCGTCTACGACATCCTCCAGA
CCGACACCCCCGGCCCCAGCTATGACCTCAGCGAACGCCTGAACGAAAAGGGCTACACCCCGCTCCAGATGGTGCAGACC
GCCGAAGCTTTCTTCACCTCGCTCGGCCTTCAGGCCCTGCCCCAGACCTTCTGGGAGCGCTCAATGATCACCAAGCCGGA
AGGCCGCGAGGTGGTCTGCCACGCGTCCGCCTGGGATCTCGATGATTTCGAAGATGTCCGCATCAAGATGTGTACGCAGG
TGAACGCCGAAGACTTCCAGACGGTCCACCACGAACTCGGCCACAACTATTATCAGCTCGCCTATCGCAACCAGGATCAC
CTCTACAAGAACGGCGCCCATGACGGCTTCCACGAAGCCATCGGGGACTTCGTCGCTCTGTCGATCACGCCGGAATATCT
CGAACAGATCGGCCTGATCACGGCGGAAGAAAAGCCCGGCGCAGACGCCGACACCGCGCTGCTCCTCAACACCGCGCTCG
ACAAGATCGCCTTCCTGCCTTTCGCTCTCTCGGTCGACAGCTGGCGCTGGGATGTGCTCTCCGGCGAAACCGCGCCTGAG
AATTATAACCAGTCCTGGACCGACATCCGCCTGAAAAACCAGGGCATCATCCCGCCCGGCCCCCGCCCGGCGGACGCCTT
CGACCCCGGCGCGAAATACCACATCCCTGGCAACACGCCGTACCTGCGCTACTTCCTCAGCTTCATCATGCAGTTCCAGT
TCCACAAGGCCGCCTGCGAACAGGCCGGCTGGGAAGGTCCGCTCCACCGCTGCTCGATCTACGGCAACAAGGAAGTCGGC
CGCCGCTTCGAGGAAATGATGGAAGCCGGCATGTCCCAACCCTGGCCCGACACGCTCGAAAAATTCACCGGCACCCGCGA
AATGGACGGCAGCGCCATCATCGAATATTTCGACCCGCTGATGGTCTACCTGAAGGAAGAAAACGCCGGGCAAAGCTGCG
GCTGGTGA

Upstream 100 bases:

>100_bases
CTGAAGACCCGCGCACCCGCCTGATCCTTCAAGAGAGGCGGTTGACGCAAGGGCCAGTTCACGGTCTCCTGATTGGCATA
TGCCTTGGGAGGGCTCTGTC

Downstream 100 bases:

>100_bases
TCTGACACCAAAACCAGTCCCCAAACTGAGAGCCCCCCCACCCCAACCCTCCCCACCTCCGTGGGCAGGGGGCCAGTCGC
GCCCTGAGAAAAACAAACCT

Product: angiotensin-converting enzyme family protein

Products: NA

Alternate protein names: Zinc-Dependent Metallopeptidase; Angiotensin-Converting; Dipeptidyl Carboxypeptidase; Angiotensin-Converting Family Protein; Dipeptidyl Carboxydipeptidase Family; Zinc Metallopeptidase Family Protein; Angiotensin-Converting Peptidyl Dipeptidase Protein; Peptidyl-Dipeptidase Dcp; Dipeptidyl Carboxydipeptidase Family Protein

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MMRHVFKPALKSASLIAIGLALAACGPAKTTIDPDAIAMEERAIEARAFLDDAESQIAAKSHIAAQAYWDQATNITPETS
AAAAQQGAEFTKLVVSLANASKDFDVSELPPAEARKLQILRSGITLPAPSREGAAEELADITTKLDATYSTGKFMFQGRE
IDLLEASRIIQESRDPEELKAVWEGWHSIAAPMAPDYTRMVEIANEGARELGYPSLDQMWLSNYDMPPAQMEAEVQRLWS
QVEPLYKELHCYTRGRLNSYYGEAVQPAAGPIRADLLGNMWAQQWSGVYDILQTDTPGPSYDLSERLNEKGYTPLQMVQT
AEAFFTSLGLQALPQTFWERSMITKPEGREVVCHASAWDLDDFEDVRIKMCTQVNAEDFQTVHHELGHNYYQLAYRNQDH
LYKNGAHDGFHEAIGDFVALSITPEYLEQIGLITAEEKPGADADTALLLNTALDKIAFLPFALSVDSWRWDVLSGETAPE
NYNQSWTDIRLKNQGIIPPGPRPADAFDPGAKYHIPGNTPYLRYFLSFIMQFQFHKAACEQAGWEGPLHRCSIYGNKEVG
RRFEEMMEAGMSQPWPDTLEKFTGTREMDGSAIIEYFDPLMVYLKEENAGQSCGW

Sequences:

>Translated_615_residues
MMRHVFKPALKSASLIAIGLALAACGPAKTTIDPDAIAMEERAIEARAFLDDAESQIAAKSHIAAQAYWDQATNITPETS
AAAAQQGAEFTKLVVSLANASKDFDVSELPPAEARKLQILRSGITLPAPSREGAAEELADITTKLDATYSTGKFMFQGRE
IDLLEASRIIQESRDPEELKAVWEGWHSIAAPMAPDYTRMVEIANEGARELGYPSLDQMWLSNYDMPPAQMEAEVQRLWS
QVEPLYKELHCYTRGRLNSYYGEAVQPAAGPIRADLLGNMWAQQWSGVYDILQTDTPGPSYDLSERLNEKGYTPLQMVQT
AEAFFTSLGLQALPQTFWERSMITKPEGREVVCHASAWDLDDFEDVRIKMCTQVNAEDFQTVHHELGHNYYQLAYRNQDH
LYKNGAHDGFHEAIGDFVALSITPEYLEQIGLITAEEKPGADADTALLLNTALDKIAFLPFALSVDSWRWDVLSGETAPE
NYNQSWTDIRLKNQGIIPPGPRPADAFDPGAKYHIPGNTPYLRYFLSFIMQFQFHKAACEQAGWEGPLHRCSIYGNKEVG
RRFEEMMEAGMSQPWPDTLEKFTGTREMDGSAIIEYFDPLMVYLKEENAGQSCGW
>Mature_615_residues
MMRHVFKPALKSASLIAIGLALAACGPAKTTIDPDAIAMEERAIEARAFLDDAESQIAAKSHIAAQAYWDQATNITPETS
AAAAQQGAEFTKLVVSLANASKDFDVSELPPAEARKLQILRSGITLPAPSREGAAEELADITTKLDATYSTGKFMFQGRE
IDLLEASRIIQESRDPEELKAVWEGWHSIAAPMAPDYTRMVEIANEGARELGYPSLDQMWLSNYDMPPAQMEAEVQRLWS
QVEPLYKELHCYTRGRLNSYYGEAVQPAAGPIRADLLGNMWAQQWSGVYDILQTDTPGPSYDLSERLNEKGYTPLQMVQT
AEAFFTSLGLQALPQTFWERSMITKPEGREVVCHASAWDLDDFEDVRIKMCTQVNAEDFQTVHHELGHNYYQLAYRNQDH
LYKNGAHDGFHEAIGDFVALSITPEYLEQIGLITAEEKPGADADTALLLNTALDKIAFLPFALSVDSWRWDVLSGETAPE
NYNQSWTDIRLKNQGIIPPGPRPADAFDPGAKYHIPGNTPYLRYFLSFIMQFQFHKAACEQAGWEGPLHRCSIYGNKEVG
RRFEEMMEAGMSQPWPDTLEKFTGTREMDGSAIIEYFDPLMVYLKEENAGQSCGW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4503273, Length=593, Percent_Identity=41.6526138279933, Blast_Score=458, Evalue=1e-129,
Organism=Homo sapiens, GI23238214, Length=582, Percent_Identity=42.0962199312715, Blast_Score=457, Evalue=1e-128,
Organism=Homo sapiens, GI295844837, Length=582, Percent_Identity=37.8006872852234, Blast_Score=378, Evalue=1e-105,
Organism=Homo sapiens, GI11225609, Length=598, Percent_Identity=31.438127090301, Blast_Score=334, Evalue=1e-91,
Organism=Caenorhabditis elegans, GI71985287, Length=596, Percent_Identity=26.8456375838926, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24584232, Length=595, Percent_Identity=38.8235294117647, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI17137008, Length=595, Percent_Identity=38.8235294117647, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI17137262, Length=590, Percent_Identity=36.271186440678, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI85724942, Length=588, Percent_Identity=34.0136054421769, Blast_Score=339, Evalue=3e-93,
Organism=Drosophila melanogaster, GI24762773, Length=451, Percent_Identity=27.7161862527716, Blast_Score=165, Evalue=7e-41,
Organism=Drosophila melanogaster, GI22026846, Length=461, Percent_Identity=25.8134490238612, Blast_Score=138, Evalue=1e-32,
Organism=Drosophila melanogaster, GI28574153, Length=470, Percent_Identity=23.1914893617021, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 68783; Mature: 68783

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRHVFKPALKSASLIAIGLALAACGPAKTTIDPDAIAMEERAIEARAFLDDAESQIAAK
CCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SHIAAQAYWDQATNITPETSAAAAQQGAEFTKLVVSLANASKDFDVSELPPAEARKLQIL
HHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RSGITLPAPSREGAAEELADITTKLDATYSTGKFMFQGREIDLLEASRIIQESRDPEELK
HCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHH
AVWEGWHSIAAPMAPDYTRMVEIANEGARELGYPSLDQMWLSNYDMPPAQMEAEVQRLWS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
QVEPLYKELHCYTRGRLNSYYGEAVQPAAGPIRADLLGNMWAQQWSGVYDILQTDTPGPS
HHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
YDLSERLNEKGYTPLQMVQTAEAFFTSLGLQALPQTFWERSMITKPEGREVVCHASAWDL
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
DDFEDVRIKMCTQVNAEDFQTVHHELGHNYYQLAYRNQDHLYKNGAHDGFHEAIGDFVAL
CCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHEEE
SITPEYLEQIGLITAEEKPGADADTALLLNTALDKIAFLPFALSVDSWRWDVLSGETAPE
EECHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEECCCCCCCC
NYNQSWTDIRLKNQGIIPPGPRPADAFDPGAKYHIPGNTPYLRYFLSFIMQFQFHKAACE
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QAGWEGPLHRCSIYGNKEVGRRFEEMMEAGMSQPWPDTLEKFTGTREMDGSAIIEYFDPL
HCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
MVYLKEENAGQSCGW
HEEEECCCCCCCCCC
>Mature Secondary Structure
MMRHVFKPALKSASLIAIGLALAACGPAKTTIDPDAIAMEERAIEARAFLDDAESQIAAK
CCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SHIAAQAYWDQATNITPETSAAAAQQGAEFTKLVVSLANASKDFDVSELPPAEARKLQIL
HHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
RSGITLPAPSREGAAEELADITTKLDATYSTGKFMFQGREIDLLEASRIIQESRDPEELK
HCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHCCCHHHHH
AVWEGWHSIAAPMAPDYTRMVEIANEGARELGYPSLDQMWLSNYDMPPAQMEAEVQRLWS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHH
QVEPLYKELHCYTRGRLNSYYGEAVQPAAGPIRADLLGNMWAQQWSGVYDILQTDTPGPS
HHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCC
YDLSERLNEKGYTPLQMVQTAEAFFTSLGLQALPQTFWERSMITKPEGREVVCHASAWDL
CCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
DDFEDVRIKMCTQVNAEDFQTVHHELGHNYYQLAYRNQDHLYKNGAHDGFHEAIGDFVAL
CCHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCHHHHCCCCCCHHHHHHHHHEEE
SITPEYLEQIGLITAEEKPGADADTALLLNTALDKIAFLPFALSVDSWRWDVLSGETAPE
EECHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEECCCCCCCC
NYNQSWTDIRLKNQGIIPPGPRPADAFDPGAKYHIPGNTPYLRYFLSFIMQFQFHKAACE
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHH
QAGWEGPLHRCSIYGNKEVGRRFEEMMEAGMSQPWPDTLEKFTGTREMDGSAIIEYFDPL
HCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
MVYLKEENAGQSCGW
HEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA