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The map label for this gene is ptrB [H]

Identifier: 114799788

GI number: 114799788

Start: 1177145

End: 1179382

Strand: Direct

Name: ptrB [H]

Synonym: HNE_1167

Alternate gene names: 114799788

Gene position: 1177145-1179382 (Clockwise)

Preceding gene: 114797442

Following gene: 114799023

Centisome position: 31.77

GC content: 61.93

Gene sequence:

>2238_bases
ATGCGCCTTGCTGCAAATCTCGCCGGCCTATTGGCCGCCTCAACATTTTTGACTGGATGCATGACAGTGAGCCAAGACAC
TGAAACGGCCGCAACCCTGGCCGCCGAAACGCCGGCCGCCGCCCAGCCGGCGCCCCCGCTGGCCCCGCGCATCGATCACG
AGATCACGCAGGTTGGCCGCACACGGAACGACCCTTACAACTGGCTGAAGGATGAAAACTGGCAGGAGGTGATGCGCGAG
CCATCGCTGCTGCGCGCCGACATCCGCGACTACCTGCTGGCGGAGAACGCGTTCACCAAAGCCGTTCTGGAAGACCCGAC
GGCGGCCCTGCGCGAACAACTGTTTGCCGAAATGCGCGGGCGCATCAAGGAAGACGACACGTCCGTTCCCGACATTGACG
GGCCGTGGGCCTATTATACGCGCTTCCGCGAGGGCGGCGAGTATGCCGTGTTTGCGCGGCGCCCGGCTTCCGATGCGTTC
AATGACGCGGCGCCCGAGACGCTGTTGCTGGACGGCGACGCGCTGGGCGAAGGGCAGGACTATTTCTCCTTCGGTGACAT
TGAGGTGTCGCCCGATCACAAATTCATTGCCTATGGCACGGACCTCAAAGGCAGCGAATTCTATGCGATCCGCGTAAAGA
ATATCGAGACGGGCGAGGACACCGGCGTTCTGATCGAGAACGCCTATGGCCCCATGGAATGGAGCGACACCGGCAAGGCC
ATCTTCTGGGTGGCGCGCGATTCCAATGGGCGGCCGAACGCCGTTTATCAGCGCAGCCTGGAGAGCGGCGAAGACACGCT
GATCTATGAGGAGCAGGACCCCGCTTTCTTCGTCAGCATTTCGACGACCGAAAGCGAAGAGGTGATCCTGATCAATGCGT
CGGGCCATACGACCTCGGAGATCCACTGGTTCCCGGCCGATGAGCTGAACCCCACGCTGCGCACGATTGCGCCGCGCCAG
ACAGATCACGAATATTCCGTGACCCAATGGGACGGAGAATTCTACATCGTCACCAATATTGACGGGGCGGTAGACTACAA
GCTGATGAAGGCGCCGATGGAAGCGACCTCGCCGGCCGAGTGGGAAGAAGTCATCCCGCATCGTCCGGGTACGCTCATCA
TGGGCATCACGGCGCAGCAGGATTACCTGACGATCATGGAGCGCGAGGACGGCCTGCCGCGTATCGTCGTGCAGGCGCGC
GCCGATGGCGCGTCTCACTCGATCAGCTTTGATGAGGCGGCCTATGAGCTGGGCCTTGAGGGCGGGTATGATTACCAGAC
GCCGATCCTGCGCTATGAGTATGCCTCGCCCGCGACGCCGGATCAGGTGTATGATTACAATCTGATCACGCGTGAGAAGA
CCCTGCGGAAAACCCGCGAAGTGCCCTCCGGCCATAATGCAGCAGACTATGTGGTTGAGCGGATCATGGCGCCGTCCTGG
GATGGGGCGGAAGTTCCGGTCACGCTGCTGCGCCATAAGGATACGCCGGTGGACGGCACCGCGCCGCTGCTTCTGTATGG
CTACGGATCATACGGCATGTCGATGCCGGCGGATTTCCGTACCGGCCGGCTCAGCCTCGTGGATCGCGGTTTCGTCTATG
CCATTGCGCATATTCGCGGCGGCATGGAGAAGGGATACCAGTGGTATCTCGACGGCAAGCTTGAGAAGAAGACCAATACG
TTCAAGGACTTCGTGGCAGCGGGCGAGCATCTCGTCGCGCAGGGCTATGGCGCCAGAGGGCGCGTGGTTGCGCATGGCGG
CTCGGCCGGTGGTCTGCTTGTCGGCGCAGCGGCGAACATGGATCCGGAACTCTTCGGTGGCATCATTGCAGCCGTTCCGT
TCGTCGATGTGCTGAATACGATGTCGGATGAAAGTCTTCCCCTGACCCCGCCGGAATGGCCCGAATGGGGCAATCCGCTG
ACGGATGAAGCGGCCTATGAGACGATCCTGGCCTACAGCCCGTATGACCAGGTGGGTAACAAGCCCTACCCGGCGATGCT
GATCACCGGCGGCGTGACCGATCCGCGCGTCACCTATTGGGAGCCGGCAAAGTGGGCGGCGAAGCTGCGCCATGAAGCGC
CCGAAGGCGGGCCGTATTTCCTGCGCATCAATATGGATGCCGGGCATGGCGGCGCGTCGGGCCGCTTTGAAGGCTTGAAG
GAAGTGGCCACAGAGTACGCGTTCGCGCTGGCGGCAGTTGGCAAAGTCGATGGCCTGAGGATCGAGCGGGAGGAGTAG

Upstream 100 bases:

>100_bases
GGCATCGTTCTGGATTTCCGCCCCGAAGGCGAATGAAGGGCTGGACAAGTGAAGGCGGCTTCCCTCAGATATTTCGACTA
TCGATAAGGGAGCCCTTCAG

Downstream 100 bases:

>100_bases
GGCGCGTGCTCTACGCGCTCGACTGCGAGTTCAATGGTTTTGGCGGTGAGCTCATCAGTCTCGCCTTGTCAGGCGAGGCG
GGTGAGCTTTACCTTTGCCG

Product: S9A family peptidase

Products: NA

Alternate protein names: Oligopeptidase B; Protease II [H]

Number of amino acids: Translated: 745; Mature: 745

Protein sequence:

>745_residues
MRLAANLAGLLAASTFLTGCMTVSQDTETAATLAAETPAAAQPAPPLAPRIDHEITQVGRTRNDPYNWLKDENWQEVMRE
PSLLRADIRDYLLAENAFTKAVLEDPTAALREQLFAEMRGRIKEDDTSVPDIDGPWAYYTRFREGGEYAVFARRPASDAF
NDAAPETLLLDGDALGEGQDYFSFGDIEVSPDHKFIAYGTDLKGSEFYAIRVKNIETGEDTGVLIENAYGPMEWSDTGKA
IFWVARDSNGRPNAVYQRSLESGEDTLIYEEQDPAFFVSISTTESEEVILINASGHTTSEIHWFPADELNPTLRTIAPRQ
TDHEYSVTQWDGEFYIVTNIDGAVDYKLMKAPMEATSPAEWEEVIPHRPGTLIMGITAQQDYLTIMEREDGLPRIVVQAR
ADGASHSISFDEAAYELGLEGGYDYQTPILRYEYASPATPDQVYDYNLITREKTLRKTREVPSGHNAADYVVERIMAPSW
DGAEVPVTLLRHKDTPVDGTAPLLLYGYGSYGMSMPADFRTGRLSLVDRGFVYAIAHIRGGMEKGYQWYLDGKLEKKTNT
FKDFVAAGEHLVAQGYGARGRVVAHGGSAGGLLVGAAANMDPELFGGIIAAVPFVDVLNTMSDESLPLTPPEWPEWGNPL
TDEAAYETILAYSPYDQVGNKPYPAMLITGGVTDPRVTYWEPAKWAAKLRHEAPEGGPYFLRINMDAGHGGASGRFEGLK
EVATEYAFALAAVGKVDGLRIEREE

Sequences:

>Translated_745_residues
MRLAANLAGLLAASTFLTGCMTVSQDTETAATLAAETPAAAQPAPPLAPRIDHEITQVGRTRNDPYNWLKDENWQEVMRE
PSLLRADIRDYLLAENAFTKAVLEDPTAALREQLFAEMRGRIKEDDTSVPDIDGPWAYYTRFREGGEYAVFARRPASDAF
NDAAPETLLLDGDALGEGQDYFSFGDIEVSPDHKFIAYGTDLKGSEFYAIRVKNIETGEDTGVLIENAYGPMEWSDTGKA
IFWVARDSNGRPNAVYQRSLESGEDTLIYEEQDPAFFVSISTTESEEVILINASGHTTSEIHWFPADELNPTLRTIAPRQ
TDHEYSVTQWDGEFYIVTNIDGAVDYKLMKAPMEATSPAEWEEVIPHRPGTLIMGITAQQDYLTIMEREDGLPRIVVQAR
ADGASHSISFDEAAYELGLEGGYDYQTPILRYEYASPATPDQVYDYNLITREKTLRKTREVPSGHNAADYVVERIMAPSW
DGAEVPVTLLRHKDTPVDGTAPLLLYGYGSYGMSMPADFRTGRLSLVDRGFVYAIAHIRGGMEKGYQWYLDGKLEKKTNT
FKDFVAAGEHLVAQGYGARGRVVAHGGSAGGLLVGAAANMDPELFGGIIAAVPFVDVLNTMSDESLPLTPPEWPEWGNPL
TDEAAYETILAYSPYDQVGNKPYPAMLITGGVTDPRVTYWEPAKWAAKLRHEAPEGGPYFLRINMDAGHGGASGRFEGLK
EVATEYAFALAAVGKVDGLRIEREE
>Mature_745_residues
MRLAANLAGLLAASTFLTGCMTVSQDTETAATLAAETPAAAQPAPPLAPRIDHEITQVGRTRNDPYNWLKDENWQEVMRE
PSLLRADIRDYLLAENAFTKAVLEDPTAALREQLFAEMRGRIKEDDTSVPDIDGPWAYYTRFREGGEYAVFARRPASDAF
NDAAPETLLLDGDALGEGQDYFSFGDIEVSPDHKFIAYGTDLKGSEFYAIRVKNIETGEDTGVLIENAYGPMEWSDTGKA
IFWVARDSNGRPNAVYQRSLESGEDTLIYEEQDPAFFVSISTTESEEVILINASGHTTSEIHWFPADELNPTLRTIAPRQ
TDHEYSVTQWDGEFYIVTNIDGAVDYKLMKAPMEATSPAEWEEVIPHRPGTLIMGITAQQDYLTIMEREDGLPRIVVQAR
ADGASHSISFDEAAYELGLEGGYDYQTPILRYEYASPATPDQVYDYNLITREKTLRKTREVPSGHNAADYVVERIMAPSW
DGAEVPVTLLRHKDTPVDGTAPLLLYGYGSYGMSMPADFRTGRLSLVDRGFVYAIAHIRGGMEKGYQWYLDGKLEKKTNT
FKDFVAAGEHLVAQGYGARGRVVAHGGSAGGLLVGAAANMDPELFGGIIAAVPFVDVLNTMSDESLPLTPPEWPEWGNPL
TDEAAYETILAYSPYDQVGNKPYPAMLITGGVTDPRVTYWEPAKWAAKLRHEAPEGGPYFLRINMDAGHGGASGRFEGLK
EVATEYAFALAAVGKVDGLRIEREE

Specific function: Cleaves peptide bonds on the C-terminal side of lysyl and argininyl residues [H]

COG id: COG1770

COG function: function code E; Protease II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9A family [H]

Homologues:

Organism=Homo sapiens, GI284172420, Length=634, Percent_Identity=27.1293375394322, Blast_Score=210, Evalue=4e-54,
Organism=Homo sapiens, GI284172413, Length=634, Percent_Identity=27.1293375394322, Blast_Score=210, Evalue=4e-54,
Organism=Homo sapiens, GI70778815, Length=634, Percent_Identity=27.1293375394322, Blast_Score=210, Evalue=4e-54,
Organism=Homo sapiens, GI284172438, Length=634, Percent_Identity=27.1293375394322, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI284172431, Length=634, Percent_Identity=27.1293375394322, Blast_Score=209, Evalue=6e-54,
Organism=Homo sapiens, GI41349456, Length=736, Percent_Identity=24.8641304347826, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI108860686, Length=309, Percent_Identity=34.6278317152104, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI108860692, Length=260, Percent_Identity=36.9230769230769, Blast_Score=151, Evalue=2e-36,
Organism=Escherichia coli, GI1788150, Length=690, Percent_Identity=39.4202898550725, Blast_Score=467, Evalue=1e-132,
Organism=Drosophila melanogaster, GI24583414, Length=744, Percent_Identity=25.1344086021505, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI221510989, Length=705, Percent_Identity=24.3971631205674, Blast_Score=161, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002471
- InterPro:   IPR001375
- InterPro:   IPR002470
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9; PF02897 Peptidase_S9_N [H]

EC number: =3.4.21.83 [H]

Molecular weight: Translated: 82184; Mature: 82184

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00708 PRO_ENDOPEP_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAANLAGLLAASTFLTGCMTVSQDTETAATLAAETPAAAQPAPPLAPRIDHEITQVGR
CCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHCC
TRNDPYNWLKDENWQEVMREPSLLRADIRDYLLAENAFTKAVLEDPTAALREQLFAEMRG
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHC
RIKEDDTSVPDIDGPWAYYTRFREGGEYAVFARRPASDAFNDAAPETLLLDGDALGEGQD
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCC
YFSFGDIEVSPDHKFIAYGTDLKGSEFYAIRVKNIETGEDTGVLIENAYGPMEWSDTGKA
CEEECCEEECCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCE
IFWVARDSNGRPNAVYQRSLESGEDTLIYEEQDPAFFVSISTTESEEVILINASGHTTSE
EEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCE
IHWFPADELNPTLRTIAPRQTDHEYSVTQWDGEFYIVTNIDGAVDYKLMKAPMEATSPAE
EEEECCCCCCCHHHHCCCCCCCCCCEEEEECCEEEEEEECCCCCCHHHHHCCCCCCCCCC
WEEVIPHRPGTLIMGITAQQDYLTIMEREDGLPRIVVQARADGASHSISFDEAAYELGLE
HHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCC
GGYDYQTPILRYEYASPATPDQVYDYNLITREKTLRKTREVPSGHNAADYVVERIMAPSW
CCCCCCCCEEEEECCCCCCCCCEEECEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
DGAEVPVTLLRHKDTPVDGTAPLLLYGYGSYGMSMPADFRTGRLSLVDRGFVYAIAHIRG
CCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHEEHHHHHC
GMEKGYQWYLDGKLEKKTNTFKDFVAAGEHLVAQGYGARGRVVAHGGSAGGLLVGAAANM
CCCCCCEEEECCEECCCHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCCEEEEECCCC
DPELFGGIIAAVPFVDVLNTMSDESLPLTPPEWPEWGNPLTDEAAYETILAYSPYDQVGN
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHEEEEECCHHHHCC
KPYPAMLITGGVTDPRVTYWEPAKWAAKLRHEAPEGGPYFLRINMDAGHGGASGRFEGLK
CCCCEEEEECCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHH
EVATEYAFALAAVGKVDGLRIEREE
HHHHHHHHHHHHHCCCCCEEEECCC
>Mature Secondary Structure
MRLAANLAGLLAASTFLTGCMTVSQDTETAATLAAETPAAAQPAPPLAPRIDHEITQVGR
CCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHEECCCCCCCCCCCCCCCCCCHHHHHHCC
TRNDPYNWLKDENWQEVMREPSLLRADIRDYLLAENAFTKAVLEDPTAALREQLFAEMRG
CCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHC
RIKEDDTSVPDIDGPWAYYTRFREGGEYAVFARRPASDAFNDAAPETLLLDGDALGEGQD
CCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCC
YFSFGDIEVSPDHKFIAYGTDLKGSEFYAIRVKNIETGEDTGVLIENAYGPMEWSDTGKA
CEEECCEEECCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCCE
IFWVARDSNGRPNAVYQRSLESGEDTLIYEEQDPAFFVSISTTESEEVILINASGHTTSE
EEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCCE
IHWFPADELNPTLRTIAPRQTDHEYSVTQWDGEFYIVTNIDGAVDYKLMKAPMEATSPAE
EEEECCCCCCCHHHHCCCCCCCCCCEEEEECCEEEEEEECCCCCCHHHHHCCCCCCCCCC
WEEVIPHRPGTLIMGITAQQDYLTIMEREDGLPRIVVQARADGASHSISFDEAAYELGLE
HHHHCCCCCCEEEEEEECCCCEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCC
GGYDYQTPILRYEYASPATPDQVYDYNLITREKTLRKTREVPSGHNAADYVVERIMAPSW
CCCCCCCCEEEEECCCCCCCCCEEECEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
DGAEVPVTLLRHKDTPVDGTAPLLLYGYGSYGMSMPADFRTGRLSLVDRGFVYAIAHIRG
CCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCHHEEHHHHHC
GMEKGYQWYLDGKLEKKTNTFKDFVAAGEHLVAQGYGARGRVVAHGGSAGGLLVGAAANM
CCCCCCEEEECCEECCCHHHHHHHHHCCCCEEECCCCCCCEEEEECCCCCCEEEEECCCC
DPELFGGIIAAVPFVDVLNTMSDESLPLTPPEWPEWGNPLTDEAAYETILAYSPYDQVGN
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHEEEEECCHHHHCC
KPYPAMLITGGVTDPRVTYWEPAKWAAKLRHEAPEGGPYFLRINMDAGHGGASGRFEGLK
CCCCEEEEECCCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHHH
EVATEYAFALAAVGKVDGLRIEREE
HHHHHHHHHHHHHCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1769955; 9097040; 9278503 [H]