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The map label for this gene is msrB2 [H]

Identifier: 114797442

GI number: 114797442

Start: 1176673

End: 1177080

Strand: Direct

Name: msrB2 [H]

Synonym: HNE_1166

Alternate gene names: 114797442

Gene position: 1176673-1177080 (Clockwise)

Preceding gene: 114798534

Following gene: 114799788

Centisome position: 31.76

GC content: 60.78

Gene sequence:

>408_bases
ATGGCAAAGCCGAAAATCCAGCGCAGTGAACGTGAATGGCGTGAGATGCTGACCGATCAGGAATATGCGGTCGGCTTTCA
GGAGGGCACCGAACGGGCCTTCACGCCGGGCAATTACGAGAGCGAGAAGCGCAAGGGCGTCTATCACTGCAAAGGCTGTG
AGACGCCGCTCTGGTCGTCCGAGCATAAATTCGACTCAGGCACGGGCTGGCCCAGCTACTGGCAGCCGATCGGCGAAGGC
GTGGTCGCCACCAAGACCGACTTCAAGATGATCTATCCGCGCACCGAGTGCCACTGCGCCAATTGCGGCATGCATATGGG
GCACGTGTTCAAGGACGGCCCGCCGCCGACCGGACAGCGCTGGTGCATCAACGGCATCGTTCTGGATTTCCGCCCCGAAG
GCGAATGA

Upstream 100 bases:

>100_bases
CTTATTCTGTGCCCGTTCGCACGCTGCCTGAAGGCGGCATGGTGGAAGCGCGCCAGGCATGCCTATATTAGGCAGGAAAT
CAGACAGGAGGGCTGCCCCC

Downstream 100 bases:

>100_bases
AGGGCTGGACAAGTGAAGGCGGCTTCCCTCAGATATTTCGACTATCGATAAGGGAGCCCTTCAGATGCGCCTTGCTGCAA
ATCTCGCCGGCCTATTGGCC

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MAKPKIQRSEREWREMLTDQEYAVGFQEGTERAFTPGNYESEKRKGVYHCKGCETPLWSSEHKFDSGTGWPSYWQPIGEG
VVATKTDFKMIYPRTECHCANCGMHMGHVFKDGPPPTGQRWCINGIVLDFRPEGE

Sequences:

>Translated_135_residues
MAKPKIQRSEREWREMLTDQEYAVGFQEGTERAFTPGNYESEKRKGVYHCKGCETPLWSSEHKFDSGTGWPSYWQPIGEG
VVATKTDFKMIYPRTECHCANCGMHMGHVFKDGPPPTGQRWCINGIVLDFRPEGE
>Mature_134_residues
AKPKIQRSEREWREMLTDQEYAVGFQEGTERAFTPGNYESEKRKGVYHCKGCETPLWSSEHKFDSGTGWPSYWQPIGEGV
VATKTDFKMIYPRTECHCANCGMHMGHVFKDGPPPTGQRWCINGIVLDFRPEGE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=128, Percent_Identity=46.09375, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI301336162, Length=128, Percent_Identity=46.09375, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI73089054, Length=128, Percent_Identity=46.09375, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI37620216, Length=128, Percent_Identity=46.09375, Blast_Score=121, Evalue=2e-28,
Organism=Homo sapiens, GI117606353, Length=139, Percent_Identity=40.2877697841727, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788077, Length=122, Percent_Identity=43.4426229508197, Blast_Score=113, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI115532676, Length=137, Percent_Identity=34.3065693430657, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17553450, Length=137, Percent_Identity=34.3065693430657, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6319816, Length=133, Percent_Identity=33.0827067669173, Blast_Score=87, Evalue=8e-19,
Organism=Drosophila melanogaster, GI221378664, Length=127, Percent_Identity=44.8818897637795, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24645799, Length=127, Percent_Identity=44.8818897637795, Blast_Score=110, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45553335, Length=127, Percent_Identity=44.8818897637795, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21356369, Length=127, Percent_Identity=44.8818897637795, Blast_Score=109, Evalue=5e-25,
Organism=Drosophila melanogaster, GI221378662, Length=134, Percent_Identity=42.5373134328358, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24645801, Length=138, Percent_Identity=42.0289855072464, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24645804, Length=138, Percent_Identity=42.0289855072464, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15493; Mature: 15361

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPKIQRSEREWREMLTDQEYAVGFQEGTERAFTPGNYESEKRKGVYHCKGCETPLWSS
CCCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHCCCCEEECCCCCCCCCC
EHKFDSGTGWPSYWQPIGEGVVATKTDFKMIYPRTECHCANCGMHMGHVFKDGPPPTGQR
CCCCCCCCCCCHHHHHHCCCEEEECCCCEEECCCCCCEECCCCCCCCHHCCCCCCCCCCE
WCINGIVLDFRPEGE
EEECCEEEEEECCCC
>Mature Secondary Structure 
AKPKIQRSEREWREMLTDQEYAVGFQEGTERAFTPGNYESEKRKGVYHCKGCETPLWSS
CCCCCCHHHHHHHHHHCCCCCEECCCCCCCCCCCCCCCCCHHCCCCEEECCCCCCCCCC
EHKFDSGTGWPSYWQPIGEGVVATKTDFKMIYPRTECHCANCGMHMGHVFKDGPPPTGQR
CCCCCCCCCCCHHHHHHCCCEEEECCCCEEECCCCCCEECCCCCCCCHHCCCCCCCCCCE
WCINGIVLDFRPEGE
EEECCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA