Click here to switch to the map view.

The map label for this gene is phoD1 [H]

Identifier: 114799664

GI number: 114799664

Start: 1286522

End: 1288225

Strand: Direct

Name: phoD1 [H]

Synonym: HNE_1260

Alternate gene names: 114799664

Gene position: 1286522-1288225 (Clockwise)

Preceding gene: 114798460

Following gene: 114800098

Centisome position: 34.72

GC content: 65.67

Gene sequence:

>1704_bases
ATGACATGCGAGAACTCGAAAAGCCTAATGGATACAGGGATCAGCCGGCGGGAGGCGCTGCTGGGTCTGGGCGGGGGCGG
GTTTACGCTGCTGGGCGGGTGCGTGAGCACGGAGCGGGCGGCGACGGTGGATGCCGCGTTCAGCTGGGGCGTAGCGAGTG
GCGATCCGGCGCCGACATCGGTAGTGATCTGGACGCGGGCCTACAACCCTGAAGTTACGGCAGTTCCTGTCGCGTTCGAG
GTGGCGGAGGACGCAGATTTCAGGCGGATCGTGCGCCGGGGCACCGGCCTGGCGAGCGCGGCGCGGGATTATATTCTGAA
GGCCGATATCGAATCGCTGGAGCCCGGCAAACGCTACCATTACCGGTTCAAAGCGGGTCAGACCGTGTCACCACCGGGAC
AAACCAGGACACTTCAGGACACATCGGGACAGTCTGTGCGCCTGGCGGTCGCCTCCTGCGCCAATTTCGGGTCGGGCTAT
TACAACGCATACCGGGCGATTGCGGAGACGCCCGGCCTCGACGCGGTGATCCATCTTGGCGACTACATCTATGAGTATGG
GCCCGACGGGTATGACGGGGAGACGGCCAGGCGGCTGGGGCGGATTGCCGAGCCGGACCATGACGCGGTGACGCTGGCCG
ACTACCGGGCGCGCTTTGCCAGCTACCGGCGTGACCCCGACCTGCAAGCGGCCCATGCGGCGGCGCCGTTCATTGCGATC
TGGGACGATCATGAGACGGCCAACAACAGCTGGATGGGCGGGGCGGGCAATCACAAGGCTGACACGCAGGGCAGCTGGGA
GGCGCGGCGGGACGCGGCGTTGCAGGCGTATTTCGAGTGGATGCCGATGCGCGATCCCAAACCCGGCGCGGCAGCGAAGA
CACTGACGCGGACCTATGAGTTTGGAGGCATCGCCTCGCTGATCCTGATCGAGTCGCGGCTGACGGGGCGCGGGGAGGCG
CTGAGCCTGAATGGGGTCAGCGACCCGGACGCGTTCATGGCCGGGCCGCTGGCTGATCCGGCGCGGACGATGCTGGGCGC
GCCGCAGGAGGCGTGGCTGGCCGGAGAGCTGAAGCGCTCGGCCGGCGCGGGCACGGCCTGGCAGGTGTTGGGAAACCAGA
CGGTGATGGCGCCGATGCACACGCCAGATTATACGGCGATCCTGCCCGGCGACATGCTGGCGGCGATTGAGGCGAAGGGC
GGGTATTCGGCGCGCTGGATCGAGCGTTCGAAGCTGGGCCTGCCGGTGAACCTCGATTCCTGGGACGGGTATCCGGCGGC
GCGCGAGCGGCTGCTGACCTCGGCGCTGGAGGCGGAGGCCAACCTTGTTGTGCTGTCCGGCGACAGTCACATGTTCTGGG
CGAGCGATCTTTACAGGGGCAGCGACGGGGCGTTTGCGGGCATCGAGTTTGCGACAGGCAGTGTCACGTCACCGGGCGGA
TATGAGAACCTCAGCAGCGATCCGCGGATCTTCGAGATCGCCGCGCAGGCCATCCCGGAGAAGAATGCGGGCGTGCGGTT
TGCCAATGTGAAGGACAAGGGATTTCTGCTGCTGACGCTGACGCGGGAAATGGCGGAGGCGGAGTATGTGCGTGTGAGCA
CGATCCTCGACCGGGCGTTTGAAACGACCACCTTTTTGACTGCGCAGTGCCGGCGCAATGACGGTGGCCGGACAGGGCAG
ATGGAATTGTCTGTAAGCAGATAA

Upstream 100 bases:

>100_bases
CACGGACCAAAAGTCAAACATATCAGCTAACATCTCAGCATTGCGTCCGTCTCGGGGCGCTTGCACGGTGGCGCGACTGG
TCACCTGCTGGAGCGCCCTG

Downstream 100 bases:

>100_bases
AAAAAGGGCCGCAACCCGGTGTGGGTTGCGGCCTTCCCAGGAAGTATGCGCCTAGAAGCGATACGAGAGCGATGCCCCGT
AGGTGCGTGGTTTGCCTGCA

Product: alkaline phosphatase

Products: NA

Alternate protein names: PLD [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MTCENSKSLMDTGISRREALLGLGGGGFTLLGGCVSTERAATVDAAFSWGVASGDPAPTSVVIWTRAYNPEVTAVPVAFE
VAEDADFRRIVRRGTGLASAARDYILKADIESLEPGKRYHYRFKAGQTVSPPGQTRTLQDTSGQSVRLAVASCANFGSGY
YNAYRAIAETPGLDAVIHLGDYIYEYGPDGYDGETARRLGRIAEPDHDAVTLADYRARFASYRRDPDLQAAHAAAPFIAI
WDDHETANNSWMGGAGNHKADTQGSWEARRDAALQAYFEWMPMRDPKPGAAAKTLTRTYEFGGIASLILIESRLTGRGEA
LSLNGVSDPDAFMAGPLADPARTMLGAPQEAWLAGELKRSAGAGTAWQVLGNQTVMAPMHTPDYTAILPGDMLAAIEAKG
GYSARWIERSKLGLPVNLDSWDGYPAARERLLTSALEAEANLVVLSGDSHMFWASDLYRGSDGAFAGIEFATGSVTSPGG
YENLSSDPRIFEIAAQAIPEKNAGVRFANVKDKGFLLLTLTREMAEAEYVRVSTILDRAFETTTFLTAQCRRNDGGRTGQ
MELSVSR

Sequences:

>Translated_567_residues
MTCENSKSLMDTGISRREALLGLGGGGFTLLGGCVSTERAATVDAAFSWGVASGDPAPTSVVIWTRAYNPEVTAVPVAFE
VAEDADFRRIVRRGTGLASAARDYILKADIESLEPGKRYHYRFKAGQTVSPPGQTRTLQDTSGQSVRLAVASCANFGSGY
YNAYRAIAETPGLDAVIHLGDYIYEYGPDGYDGETARRLGRIAEPDHDAVTLADYRARFASYRRDPDLQAAHAAAPFIAI
WDDHETANNSWMGGAGNHKADTQGSWEARRDAALQAYFEWMPMRDPKPGAAAKTLTRTYEFGGIASLILIESRLTGRGEA
LSLNGVSDPDAFMAGPLADPARTMLGAPQEAWLAGELKRSAGAGTAWQVLGNQTVMAPMHTPDYTAILPGDMLAAIEAKG
GYSARWIERSKLGLPVNLDSWDGYPAARERLLTSALEAEANLVVLSGDSHMFWASDLYRGSDGAFAGIEFATGSVTSPGG
YENLSSDPRIFEIAAQAIPEKNAGVRFANVKDKGFLLLTLTREMAEAEYVRVSTILDRAFETTTFLTAQCRRNDGGRTGQ
MELSVSR
>Mature_566_residues
TCENSKSLMDTGISRREALLGLGGGGFTLLGGCVSTERAATVDAAFSWGVASGDPAPTSVVIWTRAYNPEVTAVPVAFEV
AEDADFRRIVRRGTGLASAARDYILKADIESLEPGKRYHYRFKAGQTVSPPGQTRTLQDTSGQSVRLAVASCANFGSGYY
NAYRAIAETPGLDAVIHLGDYIYEYGPDGYDGETARRLGRIAEPDHDAVTLADYRARFASYRRDPDLQAAHAAAPFIAIW
DDHETANNSWMGGAGNHKADTQGSWEARRDAALQAYFEWMPMRDPKPGAAAKTLTRTYEFGGIASLILIESRLTGRGEAL
SLNGVSDPDAFMAGPLADPARTMLGAPQEAWLAGELKRSAGAGTAWQVLGNQTVMAPMHTPDYTAILPGDMLAAIEAKGG
YSARWIERSKLGLPVNLDSWDGYPAARERLLTSALEAEANLVVLSGDSHMFWASDLYRGSDGAFAGIEFATGSVTSPGGY
ENLSSDPRIFEIAAQAIPEKNAGVRFANVKDKGFLLLTLTREMAEAEYVRVSTILDRAFETTTFLTAQCRRNDGGRTGQM
ELSVSR

Specific function: Catalyzes the hydrolysis of the ester bond between the phosphatidic acid and alcohol moieties of phospholipids. Can catalyze a transphosphatidylation reaction in the presence of high concentrations of primary alcohols. Has also phosphatase activity toward

COG id: COG3540

COG function: function code P; Phosphodiesterase/alkaline phosphatase D

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PhoD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018946
- InterPro:   IPR006311 [H]

Pfam domain/function: PF09423 PhoD [H]

EC number: =3.1.4.4 [H]

Molecular weight: Translated: 61049; Mature: 60918

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCENSKSLMDTGISRREALLGLGGGGFTLLGGCVSTERAATVDAAFSWGVASGDPAPTS
CCCCCCCHHHHCCCCHHHHEEECCCCCHHHCCCHHCCCCHHEEHHHHCCCCCCCCCCCCE
VVIWTRAYNPEVTAVPVAFEVAEDADFRRIVRRGTGLASAARDYILKADIESLEPGKRYH
EEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHEEEECHHHCCCCCEEE
YRFKAGQTVSPPGQTRTLQDTSGQSVRLAVASCANFGSGYYNAYRAIAETPGLDAVIHLG
EEEECCCCCCCCCCCEEEECCCCCEEEEEEEHHHCCCCHHHHHHHHHHCCCCCCEEEHHH
DYIYEYGPDGYDGETARRLGRIAEPDHDAVTLADYRARFASYRRDPDLQAAHAAAPFIAI
HHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHCCCEEEE
WDDHETANNSWMGGAGNHKADTQGSWEARRDAALQAYFEWMPMRDPKPGAAAKTLTRTYE
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
FGGIASLILIESRLTGRGEALSLNGVSDPDAFMAGPLADPARTMLGAPQEAWLAGELKRS
CCCEEEEEEEECCCCCCCCEEEECCCCCCCHHHCCCCCCHHHHHHCCCHHHHHHHHHHHC
AGAGTAWQVLGNQTVMAPMHTPDYTAILPGDMLAAIEAKGGYSARWIERSKLGLPVNLDS
CCCCEEEEEECCCEEEECCCCCCCEEECCCCEEEEEECCCCCCEEEEECCCCCCEEECCC
WDGYPAARERLLTSALEAEANLVVLSGDSHMFWASDLYRGSDGAFAGIEFATGSVTSPGG
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEHHHCCCCCCCEEEEEEECCCCCCCCC
YENLSSDPRIFEIAAQAIPEKNAGVRFANVKDKGFLLLTLTREMAEAEYVRVSTILDRAF
CCCCCCCCHHEEHHHHHCCCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
ETTTFLTAQCRRNDGGRTGQMELSVSR
HHHHEEEEEEECCCCCCCCEEEEEECC
>Mature Secondary Structure 
TCENSKSLMDTGISRREALLGLGGGGFTLLGGCVSTERAATVDAAFSWGVASGDPAPTS
CCCCCCHHHHCCCCHHHHEEECCCCCHHHCCCHHCCCCHHEEHHHHCCCCCCCCCCCCE
VVIWTRAYNPEVTAVPVAFEVAEDADFRRIVRRGTGLASAARDYILKADIESLEPGKRYH
EEEEEECCCCCCEEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHEEEECHHHCCCCCEEE
YRFKAGQTVSPPGQTRTLQDTSGQSVRLAVASCANFGSGYYNAYRAIAETPGLDAVIHLG
EEEECCCCCCCCCCCEEEECCCCCEEEEEEEHHHCCCCHHHHHHHHHHCCCCCCEEEHHH
DYIYEYGPDGYDGETARRLGRIAEPDHDAVTLADYRARFASYRRDPDLQAAHAAAPFIAI
HHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHCCCEEEE
WDDHETANNSWMGGAGNHKADTQGSWEARRDAALQAYFEWMPMRDPKPGAAAKTLTRTYE
ECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
FGGIASLILIESRLTGRGEALSLNGVSDPDAFMAGPLADPARTMLGAPQEAWLAGELKRS
CCCEEEEEEEECCCCCCCCEEEECCCCCCCHHHCCCCCCHHHHHHCCCHHHHHHHHHHHC
AGAGTAWQVLGNQTVMAPMHTPDYTAILPGDMLAAIEAKGGYSARWIERSKLGLPVNLDS
CCCCEEEEEECCCEEEECCCCCCCEEECCCCEEEEEECCCCCCEEEEECCCCCCEEECCC
WDGYPAARERLLTSALEAEANLVVLSGDSHMFWASDLYRGSDGAFAGIEFATGSVTSPGG
CCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEHHHCCCCCCCEEEEEEECCCCCCCCC
YENLSSDPRIFEIAAQAIPEKNAGVRFANVKDKGFLLLTLTREMAEAEYVRVSTILDRAF
CCCCCCCCHHEEHHHHHCCCCCCCEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
ETTTFLTAQCRRNDGGRTGQMELSVSR
HHHHEEEEEEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12441393 [H]