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The map label for this gene is betA [C]

Identifier: 114799623

GI number: 114799623

Start: 1227226

End: 1228785

Strand: Reverse

Name: betA [C]

Synonym: HNE_1208

Alternate gene names: 114799623

Gene position: 1228785-1227226 (Counterclockwise)

Preceding gene: 114797592

Following gene: 114799555

Centisome position: 33.17

GC content: 65.96

Gene sequence:

>1560_bases
ATGACCAGGCAGCATGACGCGATCGTGGTGGGCGCCGGGGCCTCGGGCGGGCTCGCGGCAGCGCTGTTGTGCGAACGCGG
AATGTCGGTCCTTCTGCTGGACGCGGGCAGCAGCTATCCGTTCTGGAAAAAGCCCCTCAGCAAAACCGTATCGGCCGCCA
TCGGTGCCGTCTCGGACCCGCGCCTGGCGAATGTTCTGCATCCGCGGCTGATCAATGCGGGGACGAAAGTGCTGCGCGGC
GTCGGGCGCATCCGCCAGCCGGTGCAGACCGAATGCTTCGCCTGGGTCCAGAAGCCCGGCATTTTTGTGGATGACCGCGA
TCACCCCTACGAGACGCCCGCCGACAAGCCGTTTACCTGGATACGCTCACATGGGGTCGGCGGCCGCATGGTGGTGCCGG
GACATGGCCGCCAGTATTACCGTTTCGGGGCGACAGACATTGGCCCGAAAGACGGCGCGCCGAGCCCCTGGCCATTCGGC
ATTGATGAGTTGGAGCCCTGGTATGAGCAGGTCGAGCGCCGTCTTGACCTGACAGGCGCGCAGGAGGGTATCGACTACAT
ACCTGACAGCGTGGTGGCCCGGCCGATTTCGCCGAATGCGTCGGAATCGGTGCTGCTGGAAACCATTCACGCCGAATGGC
CGCAGGCGTCCACGATGCTGAGCCGGTACGCGCCACCTGTGGATTTTGCCGGGATGGCGAAAGCGACCGGGCGCCTGACT
TTGCGCACGAACGCGCTGGTGCAACGCATTCTGGCCGGCCCTGACGGGCGGGCACGCGGCGCCGAATGGCTGGACCCGAT
CACGGGCGAGCGGGAGACCGCCGAGGCGCCTGTGGTGTTCCTGTGCGCATCGGCGCTGGAATCGACCCGCATCCTGCTCA
ATTCCAGTACAGCGTCTGGGCCTCTGGGAGACCAGTTGCCCGCCTTGGGGCGCTATCTGACCGACCATGTGATGGTGAAG
GCTGAAGGTATCCGCGCCGCCCTGCCCGCATCGGCGCAGGCCGAAGCCGGACGCTGTGTGTACCTGCCACGGTTTGATTT
GCGCGATGGCGGCGATGCTCACACCCGCGGGATGGGCATTCAGCTTTATCCGACGGTAAACCCGGCCGGCGCGTGGATCA
CGGCGGTGGCTTTTGGCGAATCTGCCCCGACCGCCGAAAACCGCGTATCCCTTTCAAGCGACAAGACCGACAAATGGGGC
GCGCCTGCCCTGCGCATCGAGATGCAGTGGAGCGACGCGGACCGGACGCTGGCCGCCTCCATGTCACGCGCGCTGGATGA
CCTGTTTGCAGCGCTCGGGGCAAAAGTTCTGGTGCGACCGGAGGGGCCGGCGCGCCCTGGAACATCCGTCCATGAATGCG
GCGGCGCGCGGCTGGGCACGGACGCGACGACATCGGTTCTGACGCCGCACAATGAATGCTGGGCCATGCCGGGGCTTTAC
GTCACCGATGGCGCGGCGCTGCCCTCTCAGGGCATCCAGAACCCGACGCTTACCATCATGGCATTGACGGCGCGGGCCTG
CGCGCATGTCACCGGTTCGGGTGCGTCACGCGGGATATAA

Upstream 100 bases:

>100_bases
TCTGTCAATTATTGGGGGTAATCGCCGTTCACGATCCCTCCCAGGCATCCAACATGCATAAATCGTGCAAAGCTGTAACC
GCAAAGAGGGCGGTACATAT

Downstream 100 bases:

>100_bases
CCGCATGCCCCCGGATCGGGGGCTGGCGCGCTGGCTGCAAACCGCCTTCTCTCTGCCCGGAAACGGCCAGCCTTGCCGGA
TAGGCCCGTTGAACCAACTG

Product: hypothetical protein

Products: Betaine Aldehyde; Reduced Acceptor. [C]

Alternate protein names: Oxidoreductase; Choline Dehydrogenase; Gluconate 2-Dehydrogenase; GMC Family Oxidoreductase; 2-Keto-Gluconate Dehydrogenase; Oxidoreductase Protein; GMC Oxidoreductase Family Protein; Oxidoreductase GMC Family; Glucoside 3-Dehydrogenase; Dehydrogenase; Fad Dependent Oxidoreductase; Dehydrogenase-Like Protein; Glucose Dehydrogenase; Choline Dehydrogenase And Flavoproteins-Like Protein; FAD Dependent Oxidoreductase; Dehydrogluconate Dehydrogenase; Sugar-Alcohol Dehydrogenase; Dehydrogenase Flavoprotein Subunit; Glucase Dehydrogenase Subunit Alpha; GMC Oxidoreductase; Choline Dehydrogenase-Like Flavoprotein; Gluconate 2-Dehydrogenase Flavoprotein; Flavoproteins Oxidoreductases; Oxidoreductase Chain; GMC Oxidoreductase Family; Oxidoreductase GMC Family Protein; Pyranose Oxidase; Glucose Dehydrogenase Subunit Alpha; Gluconate 2-Dehydrogenase Alpha Chain

Number of amino acids: Translated: 519; Mature: 518

Protein sequence:

>519_residues
MTRQHDAIVVGAGASGGLAAALLCERGMSVLLLDAGSSYPFWKKPLSKTVSAAIGAVSDPRLANVLHPRLINAGTKVLRG
VGRIRQPVQTECFAWVQKPGIFVDDRDHPYETPADKPFTWIRSHGVGGRMVVPGHGRQYYRFGATDIGPKDGAPSPWPFG
IDELEPWYEQVERRLDLTGAQEGIDYIPDSVVARPISPNASESVLLETIHAEWPQASTMLSRYAPPVDFAGMAKATGRLT
LRTNALVQRILAGPDGRARGAEWLDPITGERETAEAPVVFLCASALESTRILLNSSTASGPLGDQLPALGRYLTDHVMVK
AEGIRAALPASAQAEAGRCVYLPRFDLRDGGDAHTRGMGIQLYPTVNPAGAWITAVAFGESAPTAENRVSLSSDKTDKWG
APALRIEMQWSDADRTLAASMSRALDDLFAALGAKVLVRPEGPARPGTSVHECGGARLGTDATTSVLTPHNECWAMPGLY
VTDGAALPSQGIQNPTLTIMALTARACAHVTGSGASRGI

Sequences:

>Translated_519_residues
MTRQHDAIVVGAGASGGLAAALLCERGMSVLLLDAGSSYPFWKKPLSKTVSAAIGAVSDPRLANVLHPRLINAGTKVLRG
VGRIRQPVQTECFAWVQKPGIFVDDRDHPYETPADKPFTWIRSHGVGGRMVVPGHGRQYYRFGATDIGPKDGAPSPWPFG
IDELEPWYEQVERRLDLTGAQEGIDYIPDSVVARPISPNASESVLLETIHAEWPQASTMLSRYAPPVDFAGMAKATGRLT
LRTNALVQRILAGPDGRARGAEWLDPITGERETAEAPVVFLCASALESTRILLNSSTASGPLGDQLPALGRYLTDHVMVK
AEGIRAALPASAQAEAGRCVYLPRFDLRDGGDAHTRGMGIQLYPTVNPAGAWITAVAFGESAPTAENRVSLSSDKTDKWG
APALRIEMQWSDADRTLAASMSRALDDLFAALGAKVLVRPEGPARPGTSVHECGGARLGTDATTSVLTPHNECWAMPGLY
VTDGAALPSQGIQNPTLTIMALTARACAHVTGSGASRGI
>Mature_518_residues
TRQHDAIVVGAGASGGLAAALLCERGMSVLLLDAGSSYPFWKKPLSKTVSAAIGAVSDPRLANVLHPRLINAGTKVLRGV
GRIRQPVQTECFAWVQKPGIFVDDRDHPYETPADKPFTWIRSHGVGGRMVVPGHGRQYYRFGATDIGPKDGAPSPWPFGI
DELEPWYEQVERRLDLTGAQEGIDYIPDSVVARPISPNASESVLLETIHAEWPQASTMLSRYAPPVDFAGMAKATGRLTL
RTNALVQRILAGPDGRARGAEWLDPITGERETAEAPVVFLCASALESTRILLNSSTASGPLGDQLPALGRYLTDHVMVKA
EGIRAALPASAQAEAGRCVYLPRFDLRDGGDAHTRGMGIQLYPTVNPAGAWITAVAFGESAPTAENRVSLSSDKTDKWGA
PALRIEMQWSDADRTLAASMSRALDDLFAALGAKVLVRPEGPARPGTSVHECGGARLGTDATTSVLTPHNECWAMPGLYV
TDGAALPSQGIQNPTLTIMALTARACAHVTGSGASRGI

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.99.1 [C]

Molecular weight: Translated: 55161; Mature: 55030

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRQHDAIVVGAGASGGLAAALLCERGMSVLLLDAGSSYPFWKKPLSKTVSAAIGAVSDP
CCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
RLANVLHPRLINAGTKVLRGVGRIRQPVQTECFAWVQKPGIFVDDRDHPYETPADKPFTW
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHH
IRSHGVGGRMVVPGHGRQYYRFGATDIGPKDGAPSPWPFGIDELEPWYEQVERRLDLTGA
HHHCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCH
QEGIDYIPDSVVARPISPNASESVLLETIHAEWPQASTMLSRYAPPVDFAGMAKATGRLT
HHHHHHCCHHHEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHCCCEEE
LRTNALVQRILAGPDGRARGAEWLDPITGERETAEAPVVFLCASALESTRILLNSSTASG
EEHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEEHHHHHCEEEEEECCCCCC
PLGDQLPALGRYLTDHVMVKAEGIRAALPASAQAEAGRCVYLPRFDLRDGGDAHTRGMGI
CCCCHHHHHHHHHHHHEEEEECCCEEECCCCCCCCCCCEEEECCCCCCCCCCCHHCCCCE
QLYPTVNPAGAWITAVAFGESAPTAENRVSLSSDKTDKWGAPALRIEMQWSDADRTLAAS
EEEECCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHH
MSRALDDLFAALGAKVLVRPEGPARPGTSVHECGGARLGTDATTSVLTPHNECWAMPGLY
HHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCEECCCCHHHCCCCCEE
VTDGAALPSQGIQNPTLTIMALTARACAHVTGSGASRGI
EECCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TRQHDAIVVGAGASGGLAAALLCERGMSVLLLDAGSSYPFWKKPLSKTVSAAIGAVSDP
CCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCC
RLANVLHPRLINAGTKVLRGVGRIRQPVQTECFAWVQKPGIFVDDRDHPYETPADKPFTW
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHH
IRSHGVGGRMVVPGHGRQYYRFGATDIGPKDGAPSPWPFGIDELEPWYEQVERRLDLTGA
HHHCCCCCEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCH
QEGIDYIPDSVVARPISPNASESVLLETIHAEWPQASTMLSRYAPPVDFAGMAKATGRLT
HHHHHHCCHHHEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCHHHCCCEEE
LRTNALVQRILAGPDGRARGAEWLDPITGERETAEAPVVFLCASALESTRILLNSSTASG
EEHHHHHHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCEEEEEHHHHHCEEEEEECCCCCC
PLGDQLPALGRYLTDHVMVKAEGIRAALPASAQAEAGRCVYLPRFDLRDGGDAHTRGMGI
CCCCHHHHHHHHHHHHEEEEECCCEEECCCCCCCCCCCEEEECCCCCCCCCCCHHCCCCE
QLYPTVNPAGAWITAVAFGESAPTAENRVSLSSDKTDKWGAPALRIEMQWSDADRTLAAS
EEEECCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEEEEECCCHHHHHHH
MSRALDDLFAALGAKVLVRPEGPARPGTSVHECGGARLGTDATTSVLTPHNECWAMPGLY
HHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCEECCCCHHHCCCCCEE
VTDGAALPSQGIQNPTLTIMALTARACAHVTGSGASRGI
EECCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Coenzyme Q [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 7 {choline}} 1.1 {phenazine}} [C]

Substrates: Choline; Acceptor [C]

Specific reaction: Choline + Acceptor = Betaine Aldehyde + Reduced Acceptor. [C]

General reaction: Redox reaction [C]

Inhibitor: 2-Dimethylaminoethanol; Betaine aldehyde; Monoethanolamine; Semicarbazide [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA