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The map label for this gene is ppx [H]

Identifier: 114799621

GI number: 114799621

Start: 1847038

End: 1848105

Strand: Direct

Name: ppx [H]

Synonym: HNE_1801

Alternate gene names: 114799621

Gene position: 1847038-1848105 (Clockwise)

Preceding gene: 114800169

Following gene: 114798748

Centisome position: 49.85

GC content: 63.2

Gene sequence:

>1068_bases
GTGCAGGCTCGCCCCAAAACCAGTCGCCCGCTGTATGCAGCGGTCGATCTGGGCACCAATAATTGCCGCCTGCTTGTGGC
GGAGCCGCGAGGGCAAACCTTCCGCGTCGTGGACTCGCACTCCCAGATCGCCAGACTGGGGGAGGGGCTCCACGATACTG
GGCGTTTGTCAGAAGCGGCCATCGAGCGCGCGCTGGATGCCCTCCACACGATTCGGCGAAAACTGCGCCATCATGGGGTG
GGTCGGGTCCGTTGCATTGCGACTGAGGCTTGCCGGAAAGCCGAGAATGGCCCGGAGTTCATTCAGAGGGTTCATTCCGA
AACCGGCCTGACCTTCAAGGTCATCGGCGCTAAGGAGGAGGCCCGGCTGGCGACAATCGGATGCCATGATCTGCTCGTTG
CGCCTGCCAAGTCCGTCCTGGTGGTGGATATTGGGGGCGGCTCGACGGAGTTGTCGCTTCTCGATGCCGAAGCCACGCGC
GGGCAGGGGCTCAAGGGCATGCTTAACCGCGCGCAGATCATCGACTGGACAAGCCTCAAGACAGGCGTTGTCACCATGAG
CGATGCTTTCCAGGGATATGACGAAGTCGCTGCCTGGCCGCTGATGCTGAACCGCGCCCGCGAGATTGTCGCTGCCTGGC
CCGGCCTTGCCAATGTGCAGCAGCGCCTTGCTGATGACGAAGGCTATCTGATCGGAACATCGGGAACGGTCACTTGCCTG
GCCGGGGTCCATCTCAAGCTTGACCGCTACCGCCGTGATAAGGTGGATGGTGCCTGGATGAGCCGCGACGAGGGCGCCGC
GACCATTGATCTGCTCCGGGAGCTGGGCGTCTCCGGCCGCGCGAAACTTCCGACCATCGGTGAGGAGCGCGCGCCCTTGA
TGCTTGCAGGCTGTTCGATCATGCAAGCCGTATGGGAAGCTTTCGAGGGCAAGCGGCTGCGCGTGGCGGATCGCGGACTT
CGTGAAGGCCTTCTATTGTCCATGATGTATGGTCAGCCCAAGAACCGGAGCCGGCGGCGCAAAGGGCGCGGCGGTCGCCC
CAGCCCTCAGGAGGCTCCAAATGAGTGA

Upstream 100 bases:

>100_bases
TACTGGTCATTTTCAGCTCCTGTGATAGACATTGCCCCAAGTTTTCCTTTCGGGCCACACCATGGCTGACAAAAAAGACC
GGGGAGAGCCGCCCAAACGT

Downstream 100 bases:

>100_bases
CGACGACAGAAGGCGGTGGAAAGGACCGGGGCCGGAACGCCAGGATTCCGGACGGCGGTCGACCGAACGCAAGGTCATTG
CCCGCAACGCCCGGACTGAG

Product: Ppx/GppA family phosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MQARPKTSRPLYAAVDLGTNNCRLLVAEPRGQTFRVVDSHSQIARLGEGLHDTGRLSEAAIERALDALHTIRRKLRHHGV
GRVRCIATEACRKAENGPEFIQRVHSETGLTFKVIGAKEEARLATIGCHDLLVAPAKSVLVVDIGGGSTELSLLDAEATR
GQGLKGMLNRAQIIDWTSLKTGVVTMSDAFQGYDEVAAWPLMLNRAREIVAAWPGLANVQQRLADDEGYLIGTSGTVTCL
AGVHLKLDRYRRDKVDGAWMSRDEGAATIDLLRELGVSGRAKLPTIGEERAPLMLAGCSIMQAVWEAFEGKRLRVADRGL
REGLLLSMMYGQPKNRSRRRKGRGGRPSPQEAPNE

Sequences:

>Translated_355_residues
MQARPKTSRPLYAAVDLGTNNCRLLVAEPRGQTFRVVDSHSQIARLGEGLHDTGRLSEAAIERALDALHTIRRKLRHHGV
GRVRCIATEACRKAENGPEFIQRVHSETGLTFKVIGAKEEARLATIGCHDLLVAPAKSVLVVDIGGGSTELSLLDAEATR
GQGLKGMLNRAQIIDWTSLKTGVVTMSDAFQGYDEVAAWPLMLNRAREIVAAWPGLANVQQRLADDEGYLIGTSGTVTCL
AGVHLKLDRYRRDKVDGAWMSRDEGAATIDLLRELGVSGRAKLPTIGEERAPLMLAGCSIMQAVWEAFEGKRLRVADRGL
REGLLLSMMYGQPKNRSRRRKGRGGRPSPQEAPNE
>Mature_355_residues
MQARPKTSRPLYAAVDLGTNNCRLLVAEPRGQTFRVVDSHSQIARLGEGLHDTGRLSEAAIERALDALHTIRRKLRHHGV
GRVRCIATEACRKAENGPEFIQRVHSETGLTFKVIGAKEEARLATIGCHDLLVAPAKSVLVVDIGGGSTELSLLDAEATR
GQGLKGMLNRAQIIDWTSLKTGVVTMSDAFQGYDEVAAWPLMLNRAREIVAAWPGLANVQQRLADDEGYLIGTSGTVTCL
AGVHLKLDRYRRDKVDGAWMSRDEGAATIDLLRELGVSGRAKLPTIGEERAPLMLAGCSIMQAVWEAFEGKRLRVADRGL
REGLLLSMMYGQPKNRSRRRKGRGGRPSPQEAPNE

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=334, Percent_Identity=27.2455089820359, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI48994966, Length=348, Percent_Identity=27.5862068965517, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 38799; Mature: 38799

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQARPKTSRPLYAAVDLGTNNCRLLVAEPRGQTFRVVDSHSQIARLGEGLHDTGRLSEAA
CCCCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCHHHHHHHHCCCCCCCHHHHHH
IERALDALHTIRRKLRHHGVGRVRCIATEACRKAENGPEFIQRVHSETGLTFKVIGAKEE
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCC
ARLATIGCHDLLVAPAKSVLVVDIGGGSTELSLLDAEATRGQGLKGMLNRAQIIDWTSLK
CEEEEECHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHEEEECCCC
TGVVTMSDAFQGYDEVAAWPLMLNRAREIVAAWPGLANVQQRLADDEGYLIGTSGTVTCL
CCEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCEEEE
AGVHLKLDRYRRDKVDGAWMSRDEGAATIDLLRELGVSGRAKLPTIGEERAPLMLAGCSI
ECCEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHH
MQAVWEAFEGKRLRVADRGLREGLLLSMMYGQPKNRSRRRKGRGGRPSPQEAPNE
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQARPKTSRPLYAAVDLGTNNCRLLVAEPRGQTFRVVDSHSQIARLGEGLHDTGRLSEAA
CCCCCCCCCCEEEEEECCCCCEEEEEECCCCCEEEEECCHHHHHHHHCCCCCCCHHHHHH
IERALDALHTIRRKLRHHGVGRVRCIATEACRKAENGPEFIQRVHSETGLTFKVIGAKEE
HHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCHHHHHHHHHCCCCEEEEECCCCC
ARLATIGCHDLLVAPAKSVLVVDIGGGSTELSLLDAEATRGQGLKGMLNRAQIIDWTSLK
CEEEEECHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHEEEECCCC
TGVVTMSDAFQGYDEVAAWPLMLNRAREIVAAWPGLANVQQRLADDEGYLIGTSGTVTCL
CCEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCEEEE
AGVHLKLDRYRRDKVDGAWMSRDEGAATIDLLRELGVSGRAKLPTIGEERAPLMLAGCSI
ECCEEEHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHH
MQAVWEAFEGKRLRVADRGLREGLLLSMMYGQPKNRSRRRKGRGGRPSPQEAPNE
HHHHHHHHCCCEEEEHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]