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The map label for this gene is cobT [H]

Identifier: 114799398

GI number: 114799398

Start: 1545079

End: 1546086

Strand: Direct

Name: cobT [H]

Synonym: HNE_1510

Alternate gene names: 114799398

Gene position: 1545079-1546086 (Clockwise)

Preceding gene: 114798045

Following gene: 114798325

Centisome position: 41.7

GC content: 63.69

Gene sequence:

>1008_bases
ATGCTTCAAACCGATTTTCAGTCATTGATCCAGAAAGCTATCGATTCCAAGACAAAGCCCGTTGGCTCGCTCGGGCGGAT
TGAGGCGTTGGCAGCCCAGCTTGCCCGGATCCAAAACACCTTGATGCCCGTTGCCGCGAGTTGCGGTCTGACCCTCTTCG
CCGGCGATCATGGCATGGCGCTCGCAGGTGTGTCGGCCTATCCGCAAGCTGTGACACGGCAGATGGTAATGAACTTCCTG
GGCGGAGGCGCCGCTGCCAATGTCTTTGCACGCACGCTGGGTGTCGACGTTGAAGTGGTTGATTGCGGGGTGGCAGGGGA
GCCGATCAACGCGCCGTCTCTGCTGTCGCGGCGGTTAGGAGCGGGGACGGCTAATGCGATTGAGCGCCCTGCCATGACCG
CTGTAGAGCTGGATAAGGCGCTGGCTAATGGTCGCGCGATCGGGGGCGATAGCGACCATGATACCGCATGTTTCGGCGAA
ATGGGCATCGGGAACACGTCGTCGGCGAGCCTCGTTGCGGCGAAGATTCTTGGCTATCCCGTGGCAGATCTTGTTGGGCG
CGGCACAGGCCTTGCCGACGATGGCCTGAAGCGGAAGCAGGCTCTGCTGGAGGCAGCGGCAGGGCGAACGCCGGACAGCC
TGCCTGCAGATCACGCGCTGATGGAGTATGGGGGCTTCGAGATCGCAACTATGACCGGTGCAATGACCGCGGCGGCTGGC
GCGGGCAGGGTCGTGCTGGTTGATGGCTTCATCGCAACTGTTGCAGCCCTTTGCGCGCGCGAGCTCTCGCCGGGGTGTGC
CGCGAATTTTGTGTACGCCCACCGCTCCGCAGAAGCCGGCCATGCCCGCGTTCTGGAGGCGCTGGCGGCCAAGCCCCTCC
TCGATCTCGACATGCGGCTGGGGGAGGGCACGGGCGCGCTTCTGGCCTGGCCTCTGGTGCAGGCCGCCGCTGCGATGCTG
CGCGACATGGCAAGTTTTGAAAGCGCTGGTGTGAGCGGTCCGGCATGA

Upstream 100 bases:

>100_bases
TGACCGGCTGGCCCGATGCCGGGCGAATTCAAAAAAGTACAGCCAAAGCAAAAAGTGTATGGTTCTGCCCCAGTCCTGAA
GATAGAGCGGGTCCATGACA

Downstream 100 bases:

>100_bases
AGGACGAGTTTGCCAAACTCTGCCTGGCCATTCAGTTCCTGACGCGCATTCGTCTGCCGTTCGAGCCCGGCTATACGCCG
GCACGGATGGCAATGACCCC

Product: putative nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLQTDFQSLIQKAIDSKTKPVGSLGRIEALAAQLARIQNTLMPVAASCGLTLFAGDHGMALAGVSAYPQAVTRQMVMNFL
GGGAAANVFARTLGVDVEVVDCGVAGEPINAPSLLSRRLGAGTANAIERPAMTAVELDKALANGRAIGGDSDHDTACFGE
MGIGNTSSASLVAAKILGYPVADLVGRGTGLADDGLKRKQALLEAAAGRTPDSLPADHALMEYGGFEIATMTGAMTAAAG
AGRVVLVDGFIATVAALCARELSPGCAANFVYAHRSAEAGHARVLEALAAKPLLDLDMRLGEGTGALLAWPLVQAAAAML
RDMASFESAGVSGPA

Sequences:

>Translated_335_residues
MLQTDFQSLIQKAIDSKTKPVGSLGRIEALAAQLARIQNTLMPVAASCGLTLFAGDHGMALAGVSAYPQAVTRQMVMNFL
GGGAAANVFARTLGVDVEVVDCGVAGEPINAPSLLSRRLGAGTANAIERPAMTAVELDKALANGRAIGGDSDHDTACFGE
MGIGNTSSASLVAAKILGYPVADLVGRGTGLADDGLKRKQALLEAAAGRTPDSLPADHALMEYGGFEIATMTGAMTAAAG
AGRVVLVDGFIATVAALCARELSPGCAANFVYAHRSAEAGHARVLEALAAKPLLDLDMRLGEGTGALLAWPLVQAAAAML
RDMASFESAGVSGPA
>Mature_335_residues
MLQTDFQSLIQKAIDSKTKPVGSLGRIEALAAQLARIQNTLMPVAASCGLTLFAGDHGMALAGVSAYPQAVTRQMVMNFL
GGGAAANVFARTLGVDVEVVDCGVAGEPINAPSLLSRRLGAGTANAIERPAMTAVELDKALANGRAIGGDSDHDTACFGE
MGIGNTSSASLVAAKILGYPVADLVGRGTGLADDGLKRKQALLEAAAGRTPDSLPADHALMEYGGFEIATMTGAMTAAAG
AGRVVLVDGFIATVAALCARELSPGCAANFVYAHRSAEAGHARVLEALAAKPLLDLDMRLGEGTGALLAWPLVQAAAAML
RDMASFESAGVSGPA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=330, Percent_Identity=33.3333333333333, Blast_Score=157, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 33917; Mature: 33917

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTDFQSLIQKAIDSKTKPVGSLGRIEALAAQLARIQNTLMPVAASCGLTLFAGDHGMA
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCE
LAGVSAYPQAVTRQMVMNFLGGGAAANVFARTLGVDVEVVDCGVAGEPINAPSLLSRRLG
ECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHC
AGTANAIERPAMTAVELDKALANGRAIGGDSDHDTACFGEMGIGNTSSASLVAAKILGYP
CCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCC
VADLVGRGTGLADDGLKRKQALLEAAAGRTPDSLPADHALMEYGGFEIATMTGAMTAAAG
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEEHHHHHHHHCC
AGRVVLVDGFIATVAALCARELSPGCAANFVYAHRSAEAGHARVLEALAAKPLLDLDMRL
CCCEEEECCHHHHHHHHHHHHCCCCHHHHHHEEECCCCCHHHHHHHHHHHCCHHHHHHHC
GEGTGALLAWPLVQAAAAMLRDMASFESAGVSGPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLQTDFQSLIQKAIDSKTKPVGSLGRIEALAAQLARIQNTLMPVAASCGLTLFAGDHGMA
CCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCE
LAGVSAYPQAVTRQMVMNFLGGGAAANVFARTLGVDVEVVDCGVAGEPINAPSLLSRRLG
ECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHC
AGTANAIERPAMTAVELDKALANGRAIGGDSDHDTACFGEMGIGNTSSASLVAAKILGYP
CCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCC
VADLVGRGTGLADDGLKRKQALLEAAAGRTPDSLPADHALMEYGGFEIATMTGAMTAAAG
HHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEEEEHHHHHHHHCC
AGRVVLVDGFIATVAALCARELSPGCAANFVYAHRSAEAGHARVLEALAAKPLLDLDMRL
CCCEEEECCHHHHHHHHHHHHCCCCHHHHHHEEECCCCCHHHHHHHHHHHCCHHHHHHHC
GEGTGALLAWPLVQAAAAMLRDMASFESAGVSGPA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA