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The map label for this gene is yfjP [H]

Identifier: 114799381

GI number: 114799381

Start: 3538411

End: 3539052

Strand: Direct

Name: yfjP [H]

Synonym: HNE_3393

Alternate gene names: 114799381

Gene position: 3538411-3539052 (Clockwise)

Preceding gene: 114798585

Following gene: 114800298

Centisome position: 95.5

GC content: 65.58

Gene sequence:

>642_bases
ATGACCGCGCCAAGCCGCCGCCGGTTGAAGACAGCCTGCGAGCGCCTTGCTCTGGCAGACCCCGCCCTCGCCCGCGCCTA
TGACAGTCTCGGCGTGCCCGAATGGCGTACGAGCGAGCCCGGCTACAACATGCTGGGCCGGATGATTTCCCATCAGCAAC
TCTCCACCAAGGCCGCCGCGACGATCTGGGGCCGGGTTGAGGTGTTCCTGGGCGAAGTGACGCCGGAAACGCTGCTGGCG
GCTGATCCGGACGCCCTGCGCGCCTGCGGCCTGTCGCGCCCCAAGGTGGCCCATCTGACCTCGATTGCCGAAGCGATGGT
GACCGGAGAGCTCAATCTGGCCCGTGTTTGTGCCGCCGATCTTGATTCGGCGCGGGCAGAACTGGTTTCGGTGCGGGGGA
TTGGCCCGTGGACGGCGGAATTGTTCCTGCTCTACGCCGTGGGCGCCATGGACGCCTTCCCCATTGCCGATGTTGGCCTG
ATGGAAGCTCATAAGCAGCTTGGCCGCTACGAAACCCGCATGGAATCAAAGATATTCACCCAGCATGCAGAGATCTGGCG
ACCCCATCGCGGGGTGGCCGCGCATCTCCTCTGGGGCTGGCTGAATGCCGAGCGCGCGCGGGATTCGGCGCCAAAGGCCT
GA

Upstream 100 bases:

>100_bases
TTGACCGCAAAGCGCTTATGCCGCGTCTTGAGACGGCACTCGAAACCGCCTCCAACCGCCTTCTCGAAGAGGGCGCCGCC
GTGCAGAAGGAAAAGCTGGG

Downstream 100 bases:

>100_bases
GTAGGCGCAGCGAGGGGGCCTTGCGTTCGGCCCGCACTGTCATAATCTTATGATCGGAATCGCCTAAAGCACGGCGACAA
GGACGATGAGGAGTTTCCGT

Product: putative DNA-3-methyladenine glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTAPSRRRLKTACERLALADPALARAYDSLGVPEWRTSEPGYNMLGRMISHQQLSTKAAATIWGRVEVFLGEVTPETLLA
ADPDALRACGLSRPKVAHLTSIAEAMVTGELNLARVCAADLDSARAELVSVRGIGPWTAELFLLYAVGAMDAFPIADVGL
MEAHKQLGRYETRMESKIFTQHAEIWRPHRGVAAHLLWGWLNAERARDSAPKA

Sequences:

>Translated_213_residues
MTAPSRRRLKTACERLALADPALARAYDSLGVPEWRTSEPGYNMLGRMISHQQLSTKAAATIWGRVEVFLGEVTPETLLA
ADPDALRACGLSRPKVAHLTSIAEAMVTGELNLARVCAADLDSARAELVSVRGIGPWTAELFLLYAVGAMDAFPIADVGL
MEAHKQLGRYETRMESKIFTQHAEIWRPHRGVAAHLLWGWLNAERARDSAPKA
>Mature_212_residues
TAPSRRRLKTACERLALADPALARAYDSLGVPEWRTSEPGYNMLGRMISHQQLSTKAAATIWGRVEVFLGEVTPETLLAA
DPDALRACGLSRPKVAHLTSIAEAMVTGELNLARVCAADLDSARAELVSVRGIGPWTAELFLLYAVGAMDAFPIADVGLM
EAHKQLGRYETRMESKIFTQHAEIWRPHRGVAAHLLWGWLNAERARDSAPKA

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 23328; Mature: 23197

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPSRRRLKTACERLALADPALARAYDSLGVPEWRTSEPGYNMLGRMISHQQLSTKAAA
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TIWGRVEVFLGEVTPETLLAADPDALRACGLSRPKVAHLTSIAEAMVTGELNLARVCAAD
HHHHHHHHEECCCCHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
LDSARAELVSVRGIGPWTAELFLLYAVGAMDAFPIADVGLMEAHKQLGRYETRMESKIFT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QHAEIWRPHRGVAAHLLWGWLNAERARDSAPKA
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TAPSRRRLKTACERLALADPALARAYDSLGVPEWRTSEPGYNMLGRMISHQQLSTKAAA
CCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
TIWGRVEVFLGEVTPETLLAADPDALRACGLSRPKVAHLTSIAEAMVTGELNLARVCAAD
HHHHHHHHEECCCCHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
LDSARAELVSVRGIGPWTAELFLLYAVGAMDAFPIADVGLMEAHKQLGRYETRMESKIFT
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QHAEIWRPHRGVAAHLLWGWLNAERARDSAPKA
HHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]