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The map label for this gene is galU [H]

Identifier: 114799246

GI number: 114799246

Start: 1158315

End: 1159187

Strand: Direct

Name: galU [H]

Synonym: HNE_1147

Alternate gene names: 114799246

Gene position: 1158315-1159187 (Clockwise)

Preceding gene: 114800025

Following gene: 114797836

Centisome position: 31.26

GC content: 60.37

Gene sequence:

>873_bases
ATGCGCGTCAGAAAAGCTGTTCTTCCCGTGGCCGGGCTCGGCACGCGTGTGCTGCCTGCCACCAAGGCGATTCCGAAGGA
ATTGCTGCCCGTGGTGGACCGTCCGGTGATCCAGTATGTGGTCGATGAGGCCATCGAGGCCGGGATCGAGCACATCGTTT
TCGTCACTGGCCGCAGCAAAGGCGCCATCGAAGACTATTTCGACCATGCCTATGAGCTGGAAGCCCAGCTGAAGCTCAAG
AACAAGACCGATATTCTCAAACAGGTCGAGGCCTCGCGCCTTCCGGCCGGCTCATCCAGCTTTGTACGCCAGCAGGCGCC
GCTGGGCCTGGGCCATGCGGTATGGTGTGCGCGCGATGTGATCGGCAACGAGCCGTTTGCCGTGCTGCTTCCCGATGTGA
TCGTGAAGGGTAAGCCTTCGAGCCTGAAGCAGATGGTCGACGCCTATGACAAGGTGGGCGGCAATATCGTCGCCGTTGAC
CCTGTGCCTGAAGAGCGCGTCTCTTCCTATGGGGTGATCGCGCCGGTTTCGCGTGATGGCCGCCTGATCAAGATGTCCGG
CATGGTGGAAAAGCCGCCGCGTGACAGCGCGCCGTCTAACCTTGCCATCACCGGGCGCTACATCCTCCAGCCGGAAATCT
TTGGTCTTCTGGAAAAACAGGGCGCGGGCGCAGGCGGGGAAATCCAGCTGACCGACTCGATGGCCAAGCTGATGGAGCTT
CAGGACTTCTACGCCTACGAATTTGAAGGCTCTGTCCATGATTGCGGCAACAAGACCGGCTATTTCGATGCCGTGCTGGC
CCATGCGCTGGATAATCCGGATACGGCGGAGTTTGCCCGCGCACTGGTGAAGAAGACCGCGCAGGGGCTTTGA

Upstream 100 bases:

>100_bases
TGCAAAGCGGCGCCTGAACGGTTTTCGCGTGGCAGGCGACTTGCTAGGGATAAGCAGGTCGTGTCGTTCCGGCACTTAGA
TTCTCAGGGAGTTACCGCGC

Downstream 100 bases:

>100_bases
GCCTTCTGTAACCCGAACTGTTGCAGCCCTCACCTCCCACGCTCTTCGAGCGCGGGCCTGCTCCGGGCGTTTGCAGTGCA
AACGCTGATCCTCCGCAACC

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; General stress protein 33; GSP33; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MRVRKAVLPVAGLGTRVLPATKAIPKELLPVVDRPVIQYVVDEAIEAGIEHIVFVTGRSKGAIEDYFDHAYELEAQLKLK
NKTDILKQVEASRLPAGSSSFVRQQAPLGLGHAVWCARDVIGNEPFAVLLPDVIVKGKPSSLKQMVDAYDKVGGNIVAVD
PVPEERVSSYGVIAPVSRDGRLIKMSGMVEKPPRDSAPSNLAITGRYILQPEIFGLLEKQGAGAGGEIQLTDSMAKLMEL
QDFYAYEFEGSVHDCGNKTGYFDAVLAHALDNPDTAEFARALVKKTAQGL

Sequences:

>Translated_290_residues
MRVRKAVLPVAGLGTRVLPATKAIPKELLPVVDRPVIQYVVDEAIEAGIEHIVFVTGRSKGAIEDYFDHAYELEAQLKLK
NKTDILKQVEASRLPAGSSSFVRQQAPLGLGHAVWCARDVIGNEPFAVLLPDVIVKGKPSSLKQMVDAYDKVGGNIVAVD
PVPEERVSSYGVIAPVSRDGRLIKMSGMVEKPPRDSAPSNLAITGRYILQPEIFGLLEKQGAGAGGEIQLTDSMAKLMEL
QDFYAYEFEGSVHDCGNKTGYFDAVLAHALDNPDTAEFARALVKKTAQGL
>Mature_290_residues
MRVRKAVLPVAGLGTRVLPATKAIPKELLPVVDRPVIQYVVDEAIEAGIEHIVFVTGRSKGAIEDYFDHAYELEAQLKLK
NKTDILKQVEASRLPAGSSSFVRQQAPLGLGHAVWCARDVIGNEPFAVLLPDVIVKGKPSSLKQMVDAYDKVGGNIVAVD
PVPEERVSSYGVIAPVSRDGRLIKMSGMVEKPPRDSAPSNLAITGRYILQPEIFGLLEKQGAGAGGEIQLTDSMAKLMEL
QDFYAYEFEGSVHDCGNKTGYFDAVLAHALDNPDTAEFARALVKKTAQGL

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membr

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=263, Percent_Identity=26.615969581749, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1787488, Length=281, Percent_Identity=49.4661921708185, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1788355, Length=290, Percent_Identity=41.3793103448276, Blast_Score=218, Evalue=4e-58,
Organism=Escherichia coli, GI1788351, Length=241, Percent_Identity=27.3858921161826, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790224, Length=228, Percent_Identity=25.4385964912281, Blast_Score=61, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320148, Length=267, Percent_Identity=27.3408239700375, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 31351; Mature: 31351

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVRKAVLPVAGLGTRVLPATKAIPKELLPVVDRPVIQYVVDEAIEAGIEHIVFVTGRSK
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
GAIEDYFDHAYELEAQLKLKNKTDILKQVEASRLPAGSSSFVRQQAPLGLGHAVWCARDV
CCHHHHHHHHHEEHHEEEECCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHH
IGNEPFAVLLPDVIVKGKPSSLKQMVDAYDKVGGNIVAVDPVPEERVSSYGVIAPVSRDG
HCCCCCEEECCHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCEEEEECCCC
RLIKMSGMVEKPPRDSAPSNLAITGRYILQPEIFGLLEKQGAGAGGEIQLTDSMAKLMEL
EEEEECCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
QDFYAYEFEGSVHDCGNKTGYFDAVLAHALDNPDTAEFARALVKKTAQGL
HHHHEEEECCCHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVRKAVLPVAGLGTRVLPATKAIPKELLPVVDRPVIQYVVDEAIEAGIEHIVFVTGRSK
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
GAIEDYFDHAYELEAQLKLKNKTDILKQVEASRLPAGSSSFVRQQAPLGLGHAVWCARDV
CCHHHHHHHHHEEHHEEEECCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHH
IGNEPFAVLLPDVIVKGKPSSLKQMVDAYDKVGGNIVAVDPVPEERVSSYGVIAPVSRDG
HCCCCCEEECCHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHCCCEEEEECCCC
RLIKMSGMVEKPPRDSAPSNLAITGRYILQPEIFGLLEKQGAGAGGEIQLTDSMAKLMEL
EEEEECCCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHHCCCCCCCEEEEHHHHHHHHHH
QDFYAYEFEGSVHDCGNKTGYFDAVLAHALDNPDTAEFARALVKKTAQGL
HHHHEEEECCCHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8320212; 8126437; 9384377; 9298659 [H]