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The map label for this gene is yfnA [H]

Identifier: 114799061

GI number: 114799061

Start: 2753020

End: 2754342

Strand: Reverse

Name: yfnA [H]

Synonym: HNE_2593

Alternate gene names: 114799061

Gene position: 2754342-2753020 (Counterclockwise)

Preceding gene: 114798265

Following gene: 114799891

Centisome position: 74.34

GC content: 61.68

Gene sequence:

>1323_bases
ATGTCTGATGCCCCGCCTGCTGCCGATGGCCTGAAGCGCAATGTCGGCCTGTTCGGCGTTGTGTCGCTGGGGCTCGGGAC
GGCGGTGGGGGTGTCGATCTTCTCGATCCTGGCGCCGGCAGCCGCCGTGGCTGGGCCAGCCATGCTGGTGTCGATGGTGA
TTGCCATTGTGCCGATGATTGTCTTTGCGCTGATCTATTCCTTCATGGGCGCCGCGGCGCCAGCGACGGGTGCTTCATTT
GAATGGCCCCGGCGGTTTGTGCATCCTTTCGCGGGGTTTATCATCAGCTGGATGCGGATTGCCGGCAGCACAGCAGCGCT
GATCGTGCTGACAATGGTGCTGGTATCCTACATGTCGTCCCTGATTGCCTTGCCCACAAAGCTGGTGATGTTTGGCATTT
TTGCCGCGATATTCCTGATAAATCTGGCAGGCGTTTCGTTTGTGGCGCGCAGCCAGGCCGTGATGCTGGTGATCCTGCTG
GCCACGTGCGCGGTATTCGTGTTTGGCGGGGCGGGGCATGTTGAGCCAGCCAATTTCCAGCCCTTCGCGGACAAGGGCAT
TCTGGGCATTCTGGCCGCCATTCCCCTGCTGATCTCCCTGTTCCTGGGCATTGAGAGTGCGACGGAAGTGGGCGGGGAAG
TGCGCAATCCGCGGCGGAATATCCCGCTGGGCATCGGCATTTCAGTGGCACTGACGGCGGCGATCTATTTCGGGGTAGCG
GTCATCGCGATCGGCATTCTGGGCGCCGCTGCGCTGGGCGCGTCGTCTGCGCCGCTGCTGGACGCGGCGCTGGTCTCGCT
TGGTGAGGGCGGGCGGGCGCTCATTCTGGTCTGCGCTTTTGTGGCCATTGGCAGCTCGATCAATGCCACTTTCGTCATCA
TGACGCGGTTTCTCTATGCGATGTCGCGGGCAGGGATGCTGCCATCCTTCCTGGGCAAGACGAATGAGGCGCGGGGTATT
CCGCAGAACGCCGTTTTCCTCGCTTTTGGTCTCTGCTGCCTCGGCCTGTTTATGCCGCAGAACCTCGTTTTTCTGTTCCT
CGCGGTGAACATTCCGACGATCCTGAAATATGCCGCGACCTGTCTTGCTGCGATTGGTCTCTGCCGCCGGGAGCCGGAGC
TGCGCGCCGCCGCTTCGTTCAGCCTGCCAGCGAACATTGTTTATGCGCTGGCCGGGGCCGGTATCGTTCTGGGGTTCCTG
ATTATCCTTTTGGGCATTTCGGCTGACTGGCGCCCCTATGTCCTGTTGGGGGGCTGGGCCACGCTGGGGATCGCCTACTA
TCTCTTCTATCTGCGTCCGCGCGGGGCCGGGACAGCGCCTTAA

Upstream 100 bases:

>100_bases
CCGCCTGAAAGGCTGAGCGAAGGGCTTGGGCGCCTCGCCAGCGGACTTGCGGCGTATCGCGCCAGCGGCCAGAAGCGCCA
TATTGCCTGAGGAAGTTACC

Downstream 100 bases:

>100_bases
CCCTGCCCGGCAGAAATATTCCCCAGCCGGGCGTTGGAGAATAATTGTTGCCGAAGGCGGGGCGGGCCTGTCGCAAATAG
TATAAAAAAACCGTCATCTG

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSDAPPAADGLKRNVGLFGVVSLGLGTAVGVSIFSILAPAAAVAGPAMLVSMVIAIVPMIVFALIYSFMGAAAPATGASF
EWPRRFVHPFAGFIISWMRIAGSTAALIVLTMVLVSYMSSLIALPTKLVMFGIFAAIFLINLAGVSFVARSQAVMLVILL
ATCAVFVFGGAGHVEPANFQPFADKGILGILAAIPLLISLFLGIESATEVGGEVRNPRRNIPLGIGISVALTAAIYFGVA
VIAIGILGAAALGASSAPLLDAALVSLGEGGRALILVCAFVAIGSSINATFVIMTRFLYAMSRAGMLPSFLGKTNEARGI
PQNAVFLAFGLCCLGLFMPQNLVFLFLAVNIPTILKYAATCLAAIGLCRREPELRAAASFSLPANIVYALAGAGIVLGFL
IILLGISADWRPYVLLGGWATLGIAYYLFYLRPRGAGTAP

Sequences:

>Translated_440_residues
MSDAPPAADGLKRNVGLFGVVSLGLGTAVGVSIFSILAPAAAVAGPAMLVSMVIAIVPMIVFALIYSFMGAAAPATGASF
EWPRRFVHPFAGFIISWMRIAGSTAALIVLTMVLVSYMSSLIALPTKLVMFGIFAAIFLINLAGVSFVARSQAVMLVILL
ATCAVFVFGGAGHVEPANFQPFADKGILGILAAIPLLISLFLGIESATEVGGEVRNPRRNIPLGIGISVALTAAIYFGVA
VIAIGILGAAALGASSAPLLDAALVSLGEGGRALILVCAFVAIGSSINATFVIMTRFLYAMSRAGMLPSFLGKTNEARGI
PQNAVFLAFGLCCLGLFMPQNLVFLFLAVNIPTILKYAATCLAAIGLCRREPELRAAASFSLPANIVYALAGAGIVLGFL
IILLGISADWRPYVLLGGWATLGIAYYLFYLRPRGAGTAP
>Mature_439_residues
SDAPPAADGLKRNVGLFGVVSLGLGTAVGVSIFSILAPAAAVAGPAMLVSMVIAIVPMIVFALIYSFMGAAAPATGASFE
WPRRFVHPFAGFIISWMRIAGSTAALIVLTMVLVSYMSSLIALPTKLVMFGIFAAIFLINLAGVSFVARSQAVMLVILLA
TCAVFVFGGAGHVEPANFQPFADKGILGILAAIPLLISLFLGIESATEVGGEVRNPRRNIPLGIGISVALTAAIYFGVAV
IAIGILGAAALGASSAPLLDAALVSLGEGGRALILVCAFVAIGSSINATFVIMTRFLYAMSRAGMLPSFLGKTNEARGIP
QNAVFLAFGLCCLGLFMPQNLVFLFLAVNIPTILKYAATCLAAIGLCRREPELRAAASFSLPANIVYALAGAGIVLGFLI
ILLGISADWRPYVLLGGWATLGIAYYLFYLRPRGAGTAP

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI2367353, Length=330, Percent_Identity=26.969696969697, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786602, Length=451, Percent_Identity=23.5033259423503, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790584, Length=234, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081869, Length=322, Percent_Identity=22.0496894409938, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786789, Length=410, Percent_Identity=23.4146341463415, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI87082250, Length=382, Percent_Identity=21.4659685863874, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221512776, Length=358, Percent_Identity=23.7430167597765, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24666159, Length=358, Percent_Identity=23.7430167597765, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24668806, Length=421, Percent_Identity=23.9904988123515, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21356285, Length=421, Percent_Identity=23.9904988123515, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24668802, Length=421, Percent_Identity=23.9904988123515, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 45493; Mature: 45362

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SDAPPAADGLKRNVGLFGVVSLGLGTAVGVSIFSILAPAAAVAGPAMLVSMVIAIVPMI
CCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFALIYSFMGAAAPATGASFEWPRRFVHPFAGFIISWMRIAGSTAALIVLTMVLVSYMSS
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LIALPTKLVMFGIFAAIFLINLAGVSFVARSQAVMLVILLATCAVFVFGGAGHVEPANFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PFADKGILGILAAIPLLISLFLGIESATEVGGEVRNPRRNIPLGIGISVALTAAIYFGVA
CCHHCHHHHHHHHHHHHHHHHHCCHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHHHH
VIAIGILGAAALGASSAPLLDAALVSLGEGGRALILVCAFVAIGSSINATFVIMTRFLYA
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
MSRAGMLPSFLGKTNEARGIPQNAVFLAFGLCCLGLFMPQNLVFLFLAVNIPTILKYAAT
HHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CLAAIGLCRREPELRAAASFSLPANIVYALAGAGIVLGFLIILLGISADWRPYVLLGGWA
HHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHH
TLGIAYYLFYLRPRGAGTAP
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]