Click here to switch to the map view.

The map label for this gene is aspC [H]

Identifier: 114798265

GI number: 114798265

Start: 2754353

End: 2755462

Strand: Reverse

Name: aspC [H]

Synonym: HNE_2594

Alternate gene names: 114798265

Gene position: 2755462-2754353 (Counterclockwise)

Preceding gene: 114797182

Following gene: 114799061

Centisome position: 74.37

GC content: 62.25

Gene sequence:

>1110_bases
ATGCTGACATTGATGCGGTCGGGCGAGCCTGGCACGATCCCTCTGTTTGAAAGCTCGGTGCCCGAGCCGGTCGACATGTT
GGGCGATATTATTCGCACGGCATTTCGCGACGGGTTCCCGGATTCCTATAAAAGCGTCTTTATGCGGAACAATCCGGATG
TGGGCGAACACCTGGCGGCGCGCTATGGTGTGCCCGAAGAGTCCATTCTCTGCACGACGGGCGCCACCAGCGCCGTTTCA
ATGATCTACACGGCGCTTCTGTCGCCGGGGGACCGGATACTGGTCGAGGCGCCGGGCTTTGACATCTTTGCCAACATGGC
GCGCGATGTGGGTGTGCAGGCCGACTTCTTCCGCCGCGAGGCGCCGGGCTTTGGCATATCGGTTGAAGGTATTCTGGAGG
CGCTGCACGCCGACACACGGATGGTGGTGCTGACGAACCTGCACAATCCGAGCGGTGCTTATGTAAGCGACGAGACGCTG
GGATCTCTGGCGCGGGCGCTGGCAGAGCGCGGTGTTCTGTTGATGCTGGACGAGGTTTACCGCGACTATCTTGGCAATGC
CGGGCCGGGCCTTGACCCGGTGCAGCATGACAATGTTCTGCGCCTCAGCAGCCTGACGAAGATTTTCGGATTGAGCACGC
TGCGGTGTGGATGGATCATCGCCGGGCGCCGCCTGCTGCGGCGGCTCAGGGATTATTCGGAGCGTGCCGATTTCAACGTG
TCGCGCCTGTCTCATTGTGTTTCTGCCGAGGTGCTGGCGAAGGCGGATGTGTTTGACCGGTGGCGCAATGACATCATGAA
CGCGTCGCGCCCGATTGTGGCGGCGGCGTTGAGCGAGATGGCAGCGCAGGGGCTGATCGCGCCAGGCGTTACCCTGCAGG
GGTGCACCTGTTTCCCGCAGCTCATTGGTGTGGAAGACACGCGCGCGCTTTCCCAATGGCTTTCGGCCAAGCAGGGCGTT
GTGGTTGTTCCGGGCGAATGTTTCGGAGCGCCGGGCTACCTTAGGGTCGGCTATGGTCTGCCGCCTGAAAGGCTGAGCGA
AGGGCTTGGGCGCCTCGCCAGCGGACTTGCGGCGTATCGCGCCAGCGGCCAGAAGCGCCATATTGCCTGA

Upstream 100 bases:

>100_bases
TGAAAACATAAAAGATTTAAAGGGTAAGGATTATCTCACAGTGGACGCATCTGACAGTTCCGACGAAAATGTCCTGAGCT
TTGCCCATTGGGTGCGGGAC

Downstream 100 bases:

>100_bases
GGAAGTTACCATGTCTGATGCCCCGCCTGCTGCCGATGGCCTGAAGCGCAATGTCGGCCTGTTCGGCGTTGTGTCGCTGG
GGCTCGGGACGGCGGTGGGG

Product: classes I and II aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MLTLMRSGEPGTIPLFESSVPEPVDMLGDIIRTAFRDGFPDSYKSVFMRNNPDVGEHLAARYGVPEESILCTTGATSAVS
MIYTALLSPGDRILVEAPGFDIFANMARDVGVQADFFRREAPGFGISVEGILEALHADTRMVVLTNLHNPSGAYVSDETL
GSLARALAERGVLLMLDEVYRDYLGNAGPGLDPVQHDNVLRLSSLTKIFGLSTLRCGWIIAGRRLLRRLRDYSERADFNV
SRLSHCVSAEVLAKADVFDRWRNDIMNASRPIVAAALSEMAAQGLIAPGVTLQGCTCFPQLIGVEDTRALSQWLSAKQGV
VVVPGECFGAPGYLRVGYGLPPERLSEGLGRLASGLAAYRASGQKRHIA

Sequences:

>Translated_369_residues
MLTLMRSGEPGTIPLFESSVPEPVDMLGDIIRTAFRDGFPDSYKSVFMRNNPDVGEHLAARYGVPEESILCTTGATSAVS
MIYTALLSPGDRILVEAPGFDIFANMARDVGVQADFFRREAPGFGISVEGILEALHADTRMVVLTNLHNPSGAYVSDETL
GSLARALAERGVLLMLDEVYRDYLGNAGPGLDPVQHDNVLRLSSLTKIFGLSTLRCGWIIAGRRLLRRLRDYSERADFNV
SRLSHCVSAEVLAKADVFDRWRNDIMNASRPIVAAALSEMAAQGLIAPGVTLQGCTCFPQLIGVEDTRALSQWLSAKQGV
VVVPGECFGAPGYLRVGYGLPPERLSEGLGRLASGLAAYRASGQKRHIA
>Mature_369_residues
MLTLMRSGEPGTIPLFESSVPEPVDMLGDIIRTAFRDGFPDSYKSVFMRNNPDVGEHLAARYGVPEESILCTTGATSAVS
MIYTALLSPGDRILVEAPGFDIFANMARDVGVQADFFRREAPGFGISVEGILEALHADTRMVVLTNLHNPSGAYVSDETL
GSLARALAERGVLLMLDEVYRDYLGNAGPGLDPVQHDNVLRLSSLTKIFGLSTLRCGWIIAGRRLLRRLRDYSERADFNV
SRLSHCVSAEVLAKADVFDRWRNDIMNASRPIVAAALSEMAAQGLIAPGVTLQGCTCFPQLIGVEDTRALSQWLSAKQGV
VVVPGECFGAPGYLRVGYGLPPERLSEGLGRLASGLAAYRASGQKRHIA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=362, Percent_Identity=20.4419889502762, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1786816, Length=271, Percent_Identity=24.3542435424354, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567369, Length=237, Percent_Identity=23.6286919831224, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=298, Percent_Identity=20.4697986577181, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=298, Percent_Identity=20.4697986577181, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 39900; Mature: 39900

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLMRSGEPGTIPLFESSVPEPVDMLGDIIRTAFRDGFPDSYKSVFMRNNPDVGEHLAA
CEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHH
RYGVPEESILCTTGATSAVSMIYTALLSPGDRILVEAPGFDIFANMARDVGVQADFFRRE
HCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHC
APGFGISVEGILEALHADTRMVVLTNLHNPSGAYVSDETLGSLARALAERGVLLMLDEVY
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHCCEEEHHHHHH
RDYLGNAGPGLDPVQHDNVLRLSSLTKIFGLSTLRCGWIIAGRRLLRRLRDYSERADFNV
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SRLSHCVSAEVLAKADVFDRWRNDIMNASRPIVAAALSEMAAQGLIAPGVTLQGCTCFPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEECCCHHHHH
LIGVEDTRALSQWLSAKQGVVVVPGECFGAPGYLRVGYGLPPERLSEGLGRLASGLAAYR
HHCCCHHHHHHHHHHCCCCEEEECCHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHH
ASGQKRHIA
CCCCCCCCC
>Mature Secondary Structure
MLTLMRSGEPGTIPLFESSVPEPVDMLGDIIRTAFRDGFPDSYKSVFMRNNPDVGEHLAA
CEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHH
RYGVPEESILCTTGATSAVSMIYTALLSPGDRILVEAPGFDIFANMARDVGVQADFFRRE
HCCCCCCCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCCCHHHHHHC
APGFGISVEGILEALHADTRMVVLTNLHNPSGAYVSDETLGSLARALAERGVLLMLDEVY
CCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCEECHHHHHHHHHHHHHCCEEEHHHHHH
RDYLGNAGPGLDPVQHDNVLRLSSLTKIFGLSTLRCGWIIAGRRLLRRLRDYSERADFNV
HHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
SRLSHCVSAEVLAKADVFDRWRNDIMNASRPIVAAALSEMAAQGLIAPGVTLQGCTCFPQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEECCCHHHHH
LIGVEDTRALSQWLSAKQGVVVVPGECFGAPGYLRVGYGLPPERLSEGLGRLASGLAAYR
HHCCCHHHHHHHHHHCCCCEEEECCHHCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHH
ASGQKRHIA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8675024 [H]