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The map label for this gene is iolG [H]

Identifier: 114798808

GI number: 114798808

Start: 727824

End: 728750

Strand: Direct

Name: iolG [H]

Synonym: HNE_0715

Alternate gene names: 114798808

Gene position: 727824-728750 (Clockwise)

Preceding gene: 114798693

Following gene: 114797652

Centisome position: 19.64

GC content: 64.83

Gene sequence:

>927_bases
ATGACCAGGCTCAAGGTAGGCGTCGCGGGCGCCGGTGTTTTCGGCAACTACCACGCTCAGAAAGCCGCCGCCTCAGCGCG
CGCAGACCTCGTCGGCATCTTCGATGTAGACCTCTCCCGCGCCCGGAAACTCGCCGATACCTTCGGCACAAAAGGCTATT
CCGATTACGCTGAATTCCTCGGCCTCTGCGACGCGGTCGTCATCGCTGTCCCTGCCATCTGGCACGAGAAACTCGCCCGC
CAGGCCATCGAAGCCCACTGCCATGTGCTGGTCGAAAAGCCCCTCGCGCTGACCCGCGTAGGCGCGCGCGATCTGGCCGA
TGAAGCCGCCGCGCGCGGCCGTATCCTGCAGGTCGGCCATCAGGAACGCTTCGTCGCGATGGCCATGGGCGTGCTGGCAA
TTGAGGAAACGCCGCTCCTGATCGAGTCCGTTCGTTCTGGTCCCCCAACGCCCGGTGGCCGGGCAGGGGATGTCTCGGTG
ATCTGGGATCTCATGATCCACGATCTTGACCTTGCCGCCATGATGCTCGGCCGCGAGTTCACCCATGTCGAAGCCACCGG
CCGCAAGGTCCATTCAGCCCATATCGACGAGGCCGAAGCGGTGTTCGATTATGCCAGCGGTGGCCAGGCAAAACTGCGCG
CCAGCCGCGCCGCCGAGTTCCGCGAACGCACCATGCGCGTGGTTTATCCGTCCGGCGAAATCGATATCGATTTCCTCACG
CGGCGCCTGAAGAACACGACGCCCTATGAAGTGCGCGTGGACATTGCCACTGACCTGCCAGACCCGCTCGGCGCCGCCGA
TGAAGGTTTCTATGCAGCGTGTCTCGGCCTCGCGCGCAGTCCTGTGCCCGCGCATGGCGCGGTCGCGGCGGTGGCGATGG
CAGAAGCCGCCGAGGCAAAAGCCTTAGCCGGCGCGCCCGCCAAATAG

Upstream 100 bases:

>100_bases
GAAAGCCCGGAGTTTGCCGCAGTGCCAGCCTGCCGCGAAGGCTTGCAGAAGCCGCCCGGCGCATGTCATGTCGCCCATAT
AAAAAGCGATCGGGGCAGGA

Downstream 100 bases:

>100_bases
TCTAGTTTGCCGCCACTTCGCGATAGACCACGCGGGCACCCGTGCGGGTTTCTTCCGGCGTCAGAAGTTTCACCAGTTCC
TTGGCGACATCATCGGGCGT

Product: Gfo/Idh/MocA family oxidoreductase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MTRLKVGVAGAGVFGNYHAQKAAASARADLVGIFDVDLSRARKLADTFGTKGYSDYAEFLGLCDAVVIAVPAIWHEKLAR
QAIEAHCHVLVEKPLALTRVGARDLADEAAARGRILQVGHQERFVAMAMGVLAIEETPLLIESVRSGPPTPGGRAGDVSV
IWDLMIHDLDLAAMMLGREFTHVEATGRKVHSAHIDEAEAVFDYASGGQAKLRASRAAEFRERTMRVVYPSGEIDIDFLT
RRLKNTTPYEVRVDIATDLPDPLGAADEGFYAACLGLARSPVPAHGAVAAVAMAEAAEAKALAGAPAK

Sequences:

>Translated_308_residues
MTRLKVGVAGAGVFGNYHAQKAAASARADLVGIFDVDLSRARKLADTFGTKGYSDYAEFLGLCDAVVIAVPAIWHEKLAR
QAIEAHCHVLVEKPLALTRVGARDLADEAAARGRILQVGHQERFVAMAMGVLAIEETPLLIESVRSGPPTPGGRAGDVSV
IWDLMIHDLDLAAMMLGREFTHVEATGRKVHSAHIDEAEAVFDYASGGQAKLRASRAAEFRERTMRVVYPSGEIDIDFLT
RRLKNTTPYEVRVDIATDLPDPLGAADEGFYAACLGLARSPVPAHGAVAAVAMAEAAEAKALAGAPAK
>Mature_307_residues
TRLKVGVAGAGVFGNYHAQKAAASARADLVGIFDVDLSRARKLADTFGTKGYSDYAEFLGLCDAVVIAVPAIWHEKLARQ
AIEAHCHVLVEKPLALTRVGARDLADEAAARGRILQVGHQERFVAMAMGVLAIEETPLLIESVRSGPPTPGGRAGDVSVI
WDLMIHDLDLAAMMLGREFTHVEATGRKVHSAHIDEAEAVFDYASGGQAKLRASRAAEFRERTMRVVYPSGEIDIDFLTR
RLKNTTPYEVRVDIATDLPDPLGAADEGFYAACLGLARSPVPAHGAVAAVAMAEAAEAKALAGAPAK

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=125, Percent_Identity=33.6, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 32763; Mature: 32632

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLKVGVAGAGVFGNYHAQKAAASARADLVGIFDVDLSRARKLADTFGTKGYSDYAEFL
CCEEEEEEECCCCCCCHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHH
GLCDAVVIAVPAIWHEKLARQAIEAHCHVLVEKPLALTRVGARDLADEAAARGRILQVGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHCCCEEECCC
QERFVAMAMGVLAIEETPLLIESVRSGPPTPGGRAGDVSVIWDLMIHDLDLAAMMLGREF
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
THVEATGRKVHSAHIDEAEAVFDYASGGQAKLRASRAAEFRERTMRVVYPSGEIDIDFLT
HEEHHCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEHHHHH
RRLKNTTPYEVRVDIATDLPDPLGAADEGFYAACLGLARSPVPAHGAVAAVAMAEAAEAK
HHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ALAGAPAK
HCCCCCCC
>Mature Secondary Structure 
TRLKVGVAGAGVFGNYHAQKAAASARADLVGIFDVDLSRARKLADTFGTKGYSDYAEFL
CEEEEEEECCCCCCCHHHHHHHHHHHHCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHH
GLCDAVVIAVPAIWHEKLARQAIEAHCHVLVEKPLALTRVGARDLADEAAARGRILQVGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHCCCEEECCC
QERFVAMAMGVLAIEETPLLIESVRSGPPTPGGRAGDVSVIWDLMIHDLDLAAMMLGREF
HHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHH
THVEATGRKVHSAHIDEAEAVFDYASGGQAKLRASRAAEFRERTMRVVYPSGEIDIDFLT
HEEHHCCCHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCEEHHHHH
RRLKNTTPYEVRVDIATDLPDPLGAADEGFYAACLGLARSPVPAHGAVAAVAMAEAAEAK
HHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
ALAGAPAK
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA