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The map label for this gene is sodA [H]

Identifier: 114798697

GI number: 114798697

Start: 1661301

End: 1662038

Strand: Reverse

Name: sodA [H]

Synonym: HNE_1624

Alternate gene names: 114798697

Gene position: 1662038-1661301 (Counterclockwise)

Preceding gene: 114797707

Following gene: 114798231

Centisome position: 44.86

GC content: 59.49

Gene sequence:

>738_bases
ATGTACAGAACACTCGCTATTGCTACAGCCGCGCTCGGCGCAGCCGCCTGCACGACCGTAACCTCCACCGCGCTTGCCAG
TGAACCCGCAGCGCCTGTCGCCACTGAAACATCCGCCGCCGCTATCACATACACCCTGCCGGACCTGCCCTACGCGTATG
ACGCGCTCGTGGGCTCCATTGATGCGCAGACCATGGAAATTCACCACAGCAAGCACCACGCAGGCTATGTGAATAACCTC
AACGCCGCACTGGCCGATGATGCGGCGCTCGCGTCGCAACCGCTTGAAGACCTGCTGGCGAATGTATCCACACATTCCAC
CGCCATCCGCAACAATGGCGGCGGCCACTACAATCACACCCTGTTCTGGACGCTCATGGCGCCCGCGGGTGAAGGTGGCG
CGCCGTCAACTGAGCTGCTTGCCGATATTGATGCGACCTTCGGATCGCTGGACGCTTTCAAGACCGAATTCAACAAAGCC
GCCACCAGCCAGTTCGGCTCCGGGTGGGCGTGGCTTGTCGTTACCGATGACGGGCTGAAAATCACGTCCACGCCCAACCA
GGACAACCCATTGATGGATGTCGCCGCTGTGCAAGGCGAGCCGCTCCTGGCTGTCGATGTCTGGGAGCACGCATATTATC
TGAGCTACCAGAATCGCCGTGCCGATTATCTCAAGACATGGTGGAACGTCGTGAACTGGAACGAGGTGAACAGCCTTTAC
GAAGCGGCTAAGTCGTAA

Upstream 100 bases:

>100_bases
GTGACCTCGCCGCTCAAAGCCCCCATATGAACTTGACCATGCGCGTTTCACGACGCCTGCAACGTTTCAAAAACGTCCTT
CAGATCAGGGAGAAGATCAT

Downstream 100 bases:

>100_bases
ATCTGACCTTCTCCGGGGAGGCCATTCGGCCTTCCCGGCCCCAATCTTCTGATAGTCAACGGAATTTCGCTTGCTATAAA
TCTCGGCAAGATGACCCCGG

Product: superoxide dismutase, Mn

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MYRTLAIATAALGAAACTTVTSTALASEPAAPVATETSAAAITYTLPDLPYAYDALVGSIDAQTMEIHHSKHHAGYVNNL
NAALADDAALASQPLEDLLANVSTHSTAIRNNGGGHYNHTLFWTLMAPAGEGGAPSTELLADIDATFGSLDAFKTEFNKA
ATSQFGSGWAWLVVTDDGLKITSTPNQDNPLMDVAAVQGEPLLAVDVWEHAYYLSYQNRRADYLKTWWNVVNWNEVNSLY
EAAKS

Sequences:

>Translated_245_residues
MYRTLAIATAALGAAACTTVTSTALASEPAAPVATETSAAAITYTLPDLPYAYDALVGSIDAQTMEIHHSKHHAGYVNNL
NAALADDAALASQPLEDLLANVSTHSTAIRNNGGGHYNHTLFWTLMAPAGEGGAPSTELLADIDATFGSLDAFKTEFNKA
ATSQFGSGWAWLVVTDDGLKITSTPNQDNPLMDVAAVQGEPLLAVDVWEHAYYLSYQNRRADYLKTWWNVVNWNEVNSLY
EAAKS
>Mature_245_residues
MYRTLAIATAALGAAACTTVTSTALASEPAAPVATETSAAAITYTLPDLPYAYDALVGSIDAQTMEIHHSKHHAGYVNNL
NAALADDAALASQPLEDLLANVSTHSTAIRNNGGGHYNHTLFWTLMAPAGEGGAPSTELLADIDATFGSLDAFKTEFNKA
ATSQFGSGWAWLVVTDDGLKITSTPNQDNPLMDVAAVQGEPLLAVDVWEHAYYLSYQNRRADYLKTWWNVVNWNEVNSLY
EAAKS

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=237, Percent_Identity=45.5696202531646, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI67782305, Length=237, Percent_Identity=45.5696202531646, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI67782309, Length=236, Percent_Identity=37.7118644067797, Blast_Score=138, Evalue=4e-33,
Organism=Escherichia coli, GI1790342, Length=209, Percent_Identity=52.1531100478469, Blast_Score=224, Evalue=4e-60,
Organism=Escherichia coli, GI1787946, Length=196, Percent_Identity=44.3877551020408, Blast_Score=158, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17506561, Length=230, Percent_Identity=39.1304347826087, Blast_Score=157, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17569479, Length=223, Percent_Identity=40.3587443946188, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6321796, Length=225, Percent_Identity=40.8888888888889, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17136812, Length=215, Percent_Identity=39.0697674418605, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 26152; Mature: 26152

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRTLAIATAALGAAACTTVTSTALASEPAAPVATETSAAAITYTLPDLPYAYDALVGSI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCC
DAQTMEIHHSKHHAGYVNNLNAALADDAALASQPLEDLLANVSTHSTAIRNNGGGHYNHT
CCCEEEEECCCCCCCCCCCCCHHHHCCHHHHHCCHHHHHHCCCHHHHEEECCCCCCCCCE
LFWTLMAPAGEGGAPSTELLADIDATFGSLDAFKTEFNKAATSQFGSGWAWLVVTDDGLK
EEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEE
ITSTPNQDNPLMDVAAVQGEPLLAVDVWEHAYYLSYQNRRADYLKTWWNVVNWNEVNSLY
EECCCCCCCCCEEEEECCCCCEEEEEECCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHH
EAAKS
HHHCC
>Mature Secondary Structure
MYRTLAIATAALGAAACTTVTSTALASEPAAPVATETSAAAITYTLPDLPYAYDALVGSI
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCC
DAQTMEIHHSKHHAGYVNNLNAALADDAALASQPLEDLLANVSTHSTAIRNNGGGHYNHT
CCCEEEEECCCCCCCCCCCCCHHHHCCHHHHHCCHHHHHHCCCHHHHEEECCCCCCCCCE
LFWTLMAPAGEGGAPSTELLADIDATFGSLDAFKTEFNKAATSQFGSGWAWLVVTDDGLK
EEEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEE
ITSTPNQDNPLMDVAAVQGEPLLAVDVWEHAYYLSYQNRRADYLKTWWNVVNWNEVNSLY
EECCCCCCCCCEEEEECCCCCEEEEEECCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHH
EAAKS
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9074511 [H]