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The map label for this gene is mdmB [H]

Identifier: 114798644

GI number: 114798644

Start: 2844834

End: 2845994

Strand: Direct

Name: mdmB [H]

Synonym: HNE_2684

Alternate gene names: 114798644

Gene position: 2844834-2845994 (Clockwise)

Preceding gene: 114798094

Following gene: 114797823

Centisome position: 76.78

GC content: 57.88

Gene sequence:

>1161_bases
ATGGACGATAGTAAACCCGCCGGTATTCTCCACACTCAGGCGCTGAATTCAGCACCGCAGGGGCCGAGATTCATTGTGCT
CGATGCAGTGCGTGGGATCGGCGCTTTGCTGGTGATTTTCGGGCATTATCACTTCGAACTCTGGCCGGAAGTGAACAGTT
TCATCATCAGCTCCAGCGGTCACCTGGTGGTCGATGTCTTCTTCCTGCTGTCCGGGTTCGTTCTGGCACACGCCTTCTAT
GACAAGCCGAGCTTCAATTTCTGGGAATACGCCAAAAAGCGCGTTTTCCGTCTCTGGCCCCTGCACGTTGTCACTTTTAT
CGCCTGCGCCGTCATCATGTTCTGGGCCGGCGACCCGATCAGTGAAAAAGGACTGCTGCTGAACTTCGTCCTGCTCCACA
ATATCGGCATCGGCGACTGGTCCACGAACAGCTTCAACTACCCTTCCTGGTCCCTGTCGGTTGAGCTTGTGGCAAATATG
GTGGTGGGCCTGATCATCCTGGCGATCCCCAATCGCCGCTGGAACAGCGCCATCCTGGCGGGGCTGATCCTCCTCAGCGC
CACAATTCTTTTCTTTACGGTCGAAAACCTCGATCAGCATGCCCGCAATGTCCTCGGCGTGGTGAATACGGGCCTGCTGC
GCGGCTTCATATCCTTCCCGCTCGGCATTCTGGCCTATCGGTTCTTTACCACTCACAGGGCGTGGTTTGACCGCACGTCC
GTCCTGCGCAGCATATGGATCGGCTTTCTGGCCGTCGTCCTTCTGGCAACATTCTGCCTGCCGGTCGCAAACCGGGTCGA
TTTCCTCTACCTGCCATTCTACGCGTTCATGATCATGGTTCTCGCCAGCCCCGGCGCTTTCTGGGAAGGCGTTCTCAGCC
GCTTCAGAATTCTCGGCACGCTGTCCTTCGCCATGTATGTGGTTCACATGATCGTTTTGAAGATCATGGAACAGATCCCC
TTCTGGCCGCAGGAATATGTCGCCGGGCTGTTCGTCGCCTGGGCGCTGTCGATCGCGCTGGCCGCGTTTGCCCACTACAA
GATTGAGCGGCCCAGCTACGCCTGGCTGACCCGGCATATGTCGAACCCGCCTGCCGGAAACAGCCTGCCGGAAATCCTCC
AGCGCAAGCTTGCGCGGCCCACCCCTTCGAGCGCCGAATAA

Upstream 100 bases:

>100_bases
GACCCGCACATTTTTGCATTGTAAATTTACCCAACTGATAGATGGCACATGTCTTGCTGAAGATGAAGATTAGCCGGCCG
TCTGAGGAACCCCGTTAAGT

Downstream 100 bases:

>100_bases
AGTCCGGATTGGAAAAGCACCCCTGCGGGGTAAAGAGGCCGCCGCCGGCGGCGTGCTGCAGGGGTGGTGGAGGGAGCTGG
ATTCGAACCAGCGTACGCTA

Product: acyltransferase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MDDSKPAGILHTQALNSAPQGPRFIVLDAVRGIGALLVIFGHYHFELWPEVNSFIISSSGHLVVDVFFLLSGFVLAHAFY
DKPSFNFWEYAKKRVFRLWPLHVVTFIACAVIMFWAGDPISEKGLLLNFVLLHNIGIGDWSTNSFNYPSWSLSVELVANM
VVGLIILAIPNRRWNSAILAGLILLSATILFFTVENLDQHARNVLGVVNTGLLRGFISFPLGILAYRFFTTHRAWFDRTS
VLRSIWIGFLAVVLLATFCLPVANRVDFLYLPFYAFMIMVLASPGAFWEGVLSRFRILGTLSFAMYVVHMIVLKIMEQIP
FWPQEYVAGLFVAWALSIALAAFAHYKIERPSYAWLTRHMSNPPAGNSLPEILQRKLARPTPSSAE

Sequences:

>Translated_386_residues
MDDSKPAGILHTQALNSAPQGPRFIVLDAVRGIGALLVIFGHYHFELWPEVNSFIISSSGHLVVDVFFLLSGFVLAHAFY
DKPSFNFWEYAKKRVFRLWPLHVVTFIACAVIMFWAGDPISEKGLLLNFVLLHNIGIGDWSTNSFNYPSWSLSVELVANM
VVGLIILAIPNRRWNSAILAGLILLSATILFFTVENLDQHARNVLGVVNTGLLRGFISFPLGILAYRFFTTHRAWFDRTS
VLRSIWIGFLAVVLLATFCLPVANRVDFLYLPFYAFMIMVLASPGAFWEGVLSRFRILGTLSFAMYVVHMIVLKIMEQIP
FWPQEYVAGLFVAWALSIALAAFAHYKIERPSYAWLTRHMSNPPAGNSLPEILQRKLARPTPSSAE
>Mature_386_residues
MDDSKPAGILHTQALNSAPQGPRFIVLDAVRGIGALLVIFGHYHFELWPEVNSFIISSSGHLVVDVFFLLSGFVLAHAFY
DKPSFNFWEYAKKRVFRLWPLHVVTFIACAVIMFWAGDPISEKGLLLNFVLLHNIGIGDWSTNSFNYPSWSLSVELVANM
VVGLIILAIPNRRWNSAILAGLILLSATILFFTVENLDQHARNVLGVVNTGLLRGFISFPLGILAYRFFTTHRAWFDRTS
VLRSIWIGFLAVVLLATFCLPVANRVDFLYLPFYAFMIMVLASPGAFWEGVLSRFRILGTLSFAMYVVHMIVLKIMEQIP
FWPQEYVAGLFVAWALSIALAAFAHYKIERPSYAWLTRHMSNPPAGNSLPEILQRKLARPTPSSAE

Specific function: Catalyzes the acylation of the mycaminose sugar during midecamycin biosynthesis [H]

COG id: COG1835

COG function: function code I; Predicted acyltransferases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002656 [H]

Pfam domain/function: PF01757 Acyl_transf_3 [H]

EC number: NA

Molecular weight: Translated: 43470; Mature: 43470

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDSKPAGILHTQALNSAPQGPRFIVLDAVRGIGALLVIFGHYHFELWPEVNSFIISSSG
CCCCCCCCCEEHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHEEECCCHHHEEECCCC
HLVVDVFFLLSGFVLAHAFYDKPSFNFWEYAKKRVFRLWPLHVVTFIACAVIMFWAGDPI
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SEKGLLLNFVLLHNIGIGDWSTNSFNYPSWSLSVELVANMVVGLIILAIPNRRWNSAILA
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
GLILLSATILFFTVENLDQHARNVLGVVNTGLLRGFISFPLGILAYRFFTTHRAWFDRTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRSIWIGFLAVVLLATFCLPVANRVDFLYLPFYAFMIMVLASPGAFWEGVLSRFRILGT
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LSFAMYVVHMIVLKIMEQIPFWPQEYVAGLFVAWALSIALAAFAHYKIERPSYAWLTRHM
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
SNPPAGNSLPEILQRKLARPTPSSAE
CCCCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDDSKPAGILHTQALNSAPQGPRFIVLDAVRGIGALLVIFGHYHFELWPEVNSFIISSSG
CCCCCCCCCEEHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHEEECCCHHHEEECCCC
HLVVDVFFLLSGFVLAHAFYDKPSFNFWEYAKKRVFRLWPLHVVTFIACAVIMFWAGDPI
CHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SEKGLLLNFVLLHNIGIGDWSTNSFNYPSWSLSVELVANMVVGLIILAIPNRRWNSAILA
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
GLILLSATILFFTVENLDQHARNVLGVVNTGLLRGFISFPLGILAYRFFTTHRAWFDRTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLRSIWIGFLAVVLLATFCLPVANRVDFLYLPFYAFMIMVLASPGAFWEGVLSRFRILGT
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LSFAMYVVHMIVLKIMEQIPFWPQEYVAGLFVAWALSIALAAFAHYKIERPSYAWLTRHM
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHC
SNPPAGNSLPEILQRKLARPTPSSAE
CCCCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]