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The map label for this gene is yrbG [C]

Identifier: 114798621

GI number: 114798621

Start: 1915649

End: 1916668

Strand: Reverse

Name: yrbG [C]

Synonym: HNE_1856

Alternate gene names: 114798621

Gene position: 1916668-1915649 (Counterclockwise)

Preceding gene: 114798008

Following gene: 114798966

Centisome position: 51.73

GC content: 58.04

Gene sequence:

>1020_bases
ATGATGTATCTTATGATCGCAGCGGGGTTGTTCCTCCTTTTTGTGGGGGGAGAAGCCCTCGTGCGCGGGTCGGTCAGCGT
GGCGCGGAAGCTCAATATTTCAGAGCTGGTTATCGGCCTCACCCTCGTCGGCTTCGGCACCTCCGTACCTGAACTCGTTA
CAAGTTTGCAGGCTGTGGGGCAGGGGGCCGTGGGTATTTCCATCGGCAACGTCGTGGGCTCCAACATCGCCAATGTGCTG
TTGGTGCTGGCGATTGCGGTTATCCTCTCTCCCATCATCGTTCACCCTAATGTGATCATGCGCGATGGCTTGTTCATGCT
TGGGGCTACAGGGTTGCTGTGCGCGCTGATCTGGTTTGACCAGTTCAGCCGGATATCCGGCTTCCTGATGTTGGCGGTGC
TTATCGGCTATCTGGTGCTTTCGATTGTTCTGGATCAGCGCCGACAGGACGGAACGGCTCAGATGCACAAGGAAGAGGGG
GAGGTGGTCGATGCTCAGTACGGACTGGTCGTTGGCATTGTCATTGCCATTGCGGGTCTTGCCGGGGTTGTTCTGGGCGC
CAACCTGCTGGTTGAGGGATCTGTGACACTCGCCCGACAAATCGGCATCAGTGAGACGGTTATCGGCCTCACAATTGTTG
CGATCGGCACGAGCCTTCCGGAATTGGCGACGTCTGTTGTGGCGGCTTTCCGCAAGAAGGCCGATGTGGCGCTGGGCAAT
GTGATCGGATCTAACCTATTCAATATATTGGGTATTTTGGGGATTACCGCGTTGGTTCAACCCTTCAGCGTGCGGGGCGA
CGCCAGCGCAGAAGCGATGGCGGGCGGTGAGCCGGTCAGCCTCATCAGCTCGGTGGATATAGGCGCGCTGGTCTTGTCAG
TGGCGCTGCTGTTCCTGTTCGCCCTGACTGGCCGCAAGCTGGCGCGCTGGGAAGGCGCAGTGTTGCTCCTGGGGTACGTG
CTCTATATGGGCCTGACGTTCGATCTCATTCCTGTACCGGCGATATTCCCCAATGGCTGA

Upstream 100 bases:

>100_bases
AGCTCAGGTTTACGATCCTTTGAGGCGAGTTTCCGGGGGGAGATGTAACTCGTATATGGGGGCTCTTATAAGGTCCGGAT
TTCAGTGGGATTAAATTCAT

Downstream 100 bases:

>100_bases
CAATCCGATCTATCAAAAACTTGGCCAGCTTGGCCAACACACCGTTCAGCCAGCGAGCCCCGAAGAGGCGCAGCTGGAGC
GGGTGGAAAACCCGCATTCC

Product: K+-dependent Na+/Ca+ exchanger related-protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MMYLMIAAGLFLLFVGGEALVRGSVSVARKLNISELVIGLTLVGFGTSVPELVTSLQAVGQGAVGISIGNVVGSNIANVL
LVLAIAVILSPIIVHPNVIMRDGLFMLGATGLLCALIWFDQFSRISGFLMLAVLIGYLVLSIVLDQRRQDGTAQMHKEEG
EVVDAQYGLVVGIVIAIAGLAGVVLGANLLVEGSVTLARQIGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGN
VIGSNLFNILGILGITALVQPFSVRGDASAEAMAGGEPVSLISSVDIGALVLSVALLFLFALTGRKLARWEGAVLLLGYV
LYMGLTFDLIPVPAIFPNG

Sequences:

>Translated_339_residues
MMYLMIAAGLFLLFVGGEALVRGSVSVARKLNISELVIGLTLVGFGTSVPELVTSLQAVGQGAVGISIGNVVGSNIANVL
LVLAIAVILSPIIVHPNVIMRDGLFMLGATGLLCALIWFDQFSRISGFLMLAVLIGYLVLSIVLDQRRQDGTAQMHKEEG
EVVDAQYGLVVGIVIAIAGLAGVVLGANLLVEGSVTLARQIGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGN
VIGSNLFNILGILGITALVQPFSVRGDASAEAMAGGEPVSLISSVDIGALVLSVALLFLFALTGRKLARWEGAVLLLGYV
LYMGLTFDLIPVPAIFPNG
>Mature_339_residues
MMYLMIAAGLFLLFVGGEALVRGSVSVARKLNISELVIGLTLVGFGTSVPELVTSLQAVGQGAVGISIGNVVGSNIANVL
LVLAIAVILSPIIVHPNVIMRDGLFMLGATGLLCALIWFDQFSRISGFLMLAVLIGYLVLSIVLDQRRQDGTAQMHKEEG
EVVDAQYGLVVGIVIAIAGLAGVVLGANLLVEGSVTLARQIGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGN
VIGSNLFNILGILGITALVQPFSVRGDASAEAMAGGEPVSLISSVDIGALVLSVALLFLFALTGRKLARWEGAVLLLGYV
LYMGLTFDLIPVPAIFPNG

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI45504369, Length=121, Percent_Identity=38.0165289256198, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI31563526, Length=143, Percent_Identity=32.8671328671329, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1789587, Length=319, Percent_Identity=31.0344827586207, Blast_Score=114, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 35046; Mature: 35046

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYLMIAAGLFLLFVGGEALVRGSVSVARKLNISELVIGLTLVGFGTSVPELVTSLQAVG
CHHHHHHHHHHHHHHCCHHHHHCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
QGAVGISIGNVVGSNIANVLLVLAIAVILSPIIVHPNVIMRDGLFMLGATGLLCALIWFD
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHH
QFSRISGFLMLAVLIGYLVLSIVLDQRRQDGTAQMHKEEGEVVDAQYGLVVGIVIAIAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECHHHHHHHHHHHHHHHH
AGVVLGANLLVEGSVTLARQIGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGN
HHHHHHCHHEEECCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VIGSNLFNILGILGITALVQPFSVRGDASAEAMAGGEPVSLISSVDIGALVLSVALLFLF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHCHHHHHHHHHHHHHHH
ALTGRKLARWEGAVLLLGYVLYMGLTFDLIPVPAIFPNG
HHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MMYLMIAAGLFLLFVGGEALVRGSVSVARKLNISELVIGLTLVGFGTSVPELVTSLQAVG
CHHHHHHHHHHHHHHCCHHHHHCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHC
QGAVGISIGNVVGSNIANVLLVLAIAVILSPIIVHPNVIMRDGLFMLGATGLLCALIWFD
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHH
QFSRISGFLMLAVLIGYLVLSIVLDQRRQDGTAQMHKEEGEVVDAQYGLVVGIVIAIAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEECHHHHHHHHHHHHHHHH
AGVVLGANLLVEGSVTLARQIGISETVIGLTIVAIGTSLPELATSVVAAFRKKADVALGN
HHHHHHCHHEEECCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VIGSNLFNILGILGITALVQPFSVRGDASAEAMAGGEPVSLISSVDIGALVLSVALLFLF
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHCHHHHHHHHHHHHHHH
ALTGRKLARWEGAVLLLGYVLYMGLTFDLIPVPAIFPNG
HHHCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]