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The map label for this gene is hsaB [H]

Identifier: 114798613

GI number: 114798613

Start: 1280094

End: 1280678

Strand: Reverse

Name: hsaB [H]

Synonym: HNE_1255

Alternate gene names: 114798613

Gene position: 1280678-1280094 (Counterclockwise)

Preceding gene: 114799386

Following gene: 114799230

Centisome position: 34.57

GC content: 63.76

Gene sequence:

>585_bases
ATGCAGCCGAAACCGCGCGCGCAAAGCCCGTATACGGCGACAATCCCTTCAGCTGACGGAAGGATTCAGAATATGACACC
TCCCATCGACACAGCTCTCTGGCGCGAAGCCATGGGCGGTTTCCTCACCGGCGTCACAGTCGTTACCACGCTCTCGGGCG
GCAAGATCGCCGGCACCGCCGTCAATGCTTTCTCAGCGCTGTCGCAGGACCCGCCGCTGCTGCTCGTCTGCCTCGACCGG
TCCAGCCGCTCGCTTGAAGCCATCCGCTCGTCGGGTTTCTTCGCCGTCAACATCCTCTCCGAGACGCATATGGAAGTCGT
CCGCCGCTTCTCCTCCAAGAGCGCTGACGACCGGTTCCGCGACGTGCCTTACACGAGCGAAGCGACCGGCGCGCCGGTCC
TCACCGGGTCTGTCGCCTGGTTTGATTGCTCCGTCCACGCCATTCATGAGGGCGGCGACCATGAGATCGTCGTGGGCCGC
GTGCTTCGCCTCGGATCGGACAACGCCGCCACGCCGCTGGCGTATCATCGCGGCAATATCTGGTGTCTTCCGGCCCGCGA
GATTGTCCCTGAAGGGCGTTCATGA

Upstream 100 bases:

>100_bases
ACCACCGGCTTCAAGCGCTGGCGCCCAACGCCGGATGATCTGGCCAAGAGCGCGCTCATCTACGCCCTCACCGCCCTCGC
CCTTTGCGGCAAGGTGGACA

Downstream 100 bases:

>100_bases
CCCCGCCTGAGAAAGCCGGAGCGCCGCATCTCACGGGCACTGCCGCGCTCGTCCGCGTCATGGCGGATACAGCCTACCGC
AATCTCTTCCTCGCCTCCAC

Product: flavin reductase family protein

Products: NAD(+); reduced flavin [C]

Alternate protein names: Flavin:NADH reductase [H]

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MQPKPRAQSPYTATIPSADGRIQNMTPPIDTALWREAMGGFLTGVTVVTTLSGGKIAGTAVNAFSALSQDPPLLLVCLDR
SSRSLEAIRSSGFFAVNILSETHMEVVRRFSSKSADDRFRDVPYTSEATGAPVLTGSVAWFDCSVHAIHEGGDHEIVVGR
VLRLGSDNAATPLAYHRGNIWCLPAREIVPEGRS

Sequences:

>Translated_194_residues
MQPKPRAQSPYTATIPSADGRIQNMTPPIDTALWREAMGGFLTGVTVVTTLSGGKIAGTAVNAFSALSQDPPLLLVCLDR
SSRSLEAIRSSGFFAVNILSETHMEVVRRFSSKSADDRFRDVPYTSEATGAPVLTGSVAWFDCSVHAIHEGGDHEIVVGR
VLRLGSDNAATPLAYHRGNIWCLPAREIVPEGRS
>Mature_194_residues
MQPKPRAQSPYTATIPSADGRIQNMTPPIDTALWREAMGGFLTGVTVVTTLSGGKIAGTAVNAFSALSQDPPLLLVCLDR
SSRSLEAIRSSGFFAVNILSETHMEVVRRFSSKSADDRFRDVPYTSEATGAPVLTGSVAWFDCSVHAIHEGGDHEIVVGR
VLRLGSDNAATPLAYHRGNIWCLPAREIVPEGRS

Specific function: Catalyzes the reduction of free flavins (FMN or FAD) by NADH. Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit [H]

COG id: COG1853

COG function: function code R; Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the non-flavoprotein flavin reductase family [H]

Homologues:

Organism=Escherichia coli, GI87081819, Length=130, Percent_Identity=28.4615384615385, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002563
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF01613 Flavin_Reduct [H]

EC number: 1.6.8.- [C]

Molecular weight: Translated: 20822; Mature: 20822

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPKPRAQSPYTATIPSADGRIQNMTPPIDTALWREAMGGFLTGVTVVTTLSGGKIAGTA
CCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCEEEHHH
VNAFSALSQDPPLLLVCLDRSSRSLEAIRSSGFFAVNILSETHMEVVRRFSSKSADDRFR
HHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHH
DVPYTSEATGAPVLTGSVAWFDCSVHAIHEGGDHEIVVGRVLRLGSDNAATPLAYHRGNI
CCCCCCCCCCCCEEECCEEEEEEEEEEEECCCCCEEEEEEHEECCCCCCCCCEEEECCCE
WCLPAREIVPEGRS
EEEEHHHHCCCCCC
>Mature Secondary Structure
MQPKPRAQSPYTATIPSADGRIQNMTPPIDTALWREAMGGFLTGVTVVTTLSGGKIAGTA
CCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCCEEEHHH
VNAFSALSQDPPLLLVCLDRSSRSLEAIRSSGFFAVNILSETHMEVVRRFSSKSADDRFR
HHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHH
DVPYTSEATGAPVLTGSVAWFDCSVHAIHEGGDHEIVVGRVLRLGSDNAATPLAYHRGNI
CCCCCCCCCCCCEEECCEEEEEEEEEEEECCCCCEEEEEEHEECCCCCCCCCEEEECCCE
WCLPAREIVPEGRS
EEEEHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; flavin [C]

Specific reaction: NADH + flavin = NAD(+) + reduced flavin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA