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The map label for this gene is rho [H]

Identifier: 114798602

GI number: 114798602

Start: 3700924

End: 3702180

Strand: Reverse

Name: rho [H]

Synonym: HNE_3565

Alternate gene names: 114798602

Gene position: 3702180-3700924 (Counterclockwise)

Preceding gene: 114798055

Following gene: 114799625

Centisome position: 99.92

GC content: 58.63

Gene sequence:

>1257_bases
GTGACTCTGCGCGAACTCAAGGCGAAATCGCCTGAAGAACTTCTCGCCTATGCAGAGGAGCTTGAGGTCGAGAACGCCTC
CTCCATGCGGACGCAGGATATGCTGTTCGCGATCCTCAAGGAGCTGGCTGACAGCGAAGTCGAGATCACGGGCCAGGGCG
TTCTGGAAGTTCTGACCGACGGGTTCGGCTTCCTCCGCTCCCCGGAATCCAACTACCTGCCAGGGCCGGACGACATCTAT
GTCAGCCCGGAAGTTCTGAAGAAGGCGAACATCCGCACCGGCGATACCGTCGAAGGCCCGATTGTCGCGCCGCAGGACAG
CGAGCGGTATTTTGCGCTGACCGATGTCAGCCAGATCAATTTCGAGGAACCGGAAAAGGCCAACAAGAAGGTTCACTTCG
ACAACCTCACCCCTCTTTATCCGGAACAGCGCCTCAAGATGGAGAGCCGCGACCCGACCAAGAAGGACCGTTCCGGCCGG
GTGATCGACATTGTCTCGCCGATCGGCAAAGGCCAGCGCGCATTGATCGTTGCCCCGCCGCGCACCGGTAAAACGGTTCT
CATGCAGAACATTGCTGCGGCGATCGAAGAGAACCACCCCGAATGTTATCTCATCGTTCTTCTGATCGATGAGCGTCCCG
AAGAAGTTACCGACATGCGCCGCACGGTGAAGGGCGAAGTTGTTGCCTCGACCTTTGACGAGCCTGCCACCCGCCACGTT
CAGGTTGCAGAAATGGTCATCGAGAAGGCGAAGCGCCTTGTTGAGCACAAGCGTGACGTTGTCATCCTGCTCGACTCGAT
CACCCGTCTGGGCCGCGCCTACAACACGACCGTTCCCTCCTCCGGCAAGGTTCTGACCGGCGGTGTGGATGCCAATGCGC
TCCAGCGCCCTAAACGCTTTTTCGGCGCCGCGCGGAATGTCGAGAATGGTGGCTCGCTCACCATCGTTGCCACCGCGCTG
ATCGATACCGGCAGCCGCATGGACGAAGTCATCTTCGAGGAATTCAAAGGCACGGGTAACTCCGAAGTCGTCCTCGACCG
GAAGATTGCCGACAAGCGGACCTTCCCGGCCATCGACATCATGAAGTCGGGCACCCGGAAAGAAGAACTCATCACCCCGC
ACGACCAGCTCTCGAAGATCTATATCCTTCGCCGTATTCTTGGCCCGATGGGCGCCAACGATGCCGTCGACTTCCTGCTC
GACAAGCTGAAGCAGACGAAGACGAACGACGAATTCTTCGAAGCGATGAAGAACTAG

Upstream 100 bases:

>100_bases
TGGCGCTGCGATGTATTTTCGCCCGGCCCCTCCCCTTTTGTACTTCTCCAGTCCGGATACTGCCCGAATGGCTTCCACGA
TGCTCGACAACCTCACCAGC

Downstream 100 bases:

>100_bases
AGGCTGGGCCGGATGGCCGCGCGCGACACAATCTGCGCTCTGGCTTCCGGCCCGCCGCCCTCGGCCATTGCCATTATCCG
GATTTCCGGTCCCGCAGTTG

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MTLRELKAKSPEELLAYAEELEVENASSMRTQDMLFAILKELADSEVEITGQGVLEVLTDGFGFLRSPESNYLPGPDDIY
VSPEVLKKANIRTGDTVEGPIVAPQDSERYFALTDVSQINFEEPEKANKKVHFDNLTPLYPEQRLKMESRDPTKKDRSGR
VIDIVSPIGKGQRALIVAPPRTGKTVLMQNIAAAIEENHPECYLIVLLIDERPEEVTDMRRTVKGEVVASTFDEPATRHV
QVAEMVIEKAKRLVEHKRDVVILLDSITRLGRAYNTTVPSSGKVLTGGVDANALQRPKRFFGAARNVENGGSLTIVATAL
IDTGSRMDEVIFEEFKGTGNSEVVLDRKIADKRTFPAIDIMKSGTRKEELITPHDQLSKIYILRRILGPMGANDAVDFLL
DKLKQTKTNDEFFEAMKN

Sequences:

>Translated_418_residues
MTLRELKAKSPEELLAYAEELEVENASSMRTQDMLFAILKELADSEVEITGQGVLEVLTDGFGFLRSPESNYLPGPDDIY
VSPEVLKKANIRTGDTVEGPIVAPQDSERYFALTDVSQINFEEPEKANKKVHFDNLTPLYPEQRLKMESRDPTKKDRSGR
VIDIVSPIGKGQRALIVAPPRTGKTVLMQNIAAAIEENHPECYLIVLLIDERPEEVTDMRRTVKGEVVASTFDEPATRHV
QVAEMVIEKAKRLVEHKRDVVILLDSITRLGRAYNTTVPSSGKVLTGGVDANALQRPKRFFGAARNVENGGSLTIVATAL
IDTGSRMDEVIFEEFKGTGNSEVVLDRKIADKRTFPAIDIMKSGTRKEELITPHDQLSKIYILRRILGPMGANDAVDFLL
DKLKQTKTNDEFFEAMKN
>Mature_417_residues
TLRELKAKSPEELLAYAEELEVENASSMRTQDMLFAILKELADSEVEITGQGVLEVLTDGFGFLRSPESNYLPGPDDIYV
SPEVLKKANIRTGDTVEGPIVAPQDSERYFALTDVSQINFEEPEKANKKVHFDNLTPLYPEQRLKMESRDPTKKDRSGRV
IDIVSPIGKGQRALIVAPPRTGKTVLMQNIAAAIEENHPECYLIVLLIDERPEEVTDMRRTVKGEVVASTFDEPATRHVQ
VAEMVIEKAKRLVEHKRDVVILLDSITRLGRAYNTTVPSSGKVLTGGVDANALQRPKRFFGAARNVENGGSLTIVATALI
DTGSRMDEVIFEEFKGTGNSEVVLDRKIADKRTFPAIDIMKSGTRKEELITPHDQLSKIYILRRILGPMGANDAVDFLLD
KLKQTKTNDEFFEAMKN

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=417, Percent_Identity=66.9064748201439, Blast_Score=584, Evalue=1e-168,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 46628; Mature: 46497

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRELKAKSPEELLAYAEELEVENASSMRTQDMLFAILKELADSEVEITGQGVLEVLTD
CCHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
GFGFLRSPESNYLPGPDDIYVSPEVLKKANIRTGDTVEGPIVAPQDSERYFALTDVSQIN
CHHHHCCCCCCCCCCCCCEEECHHHHHHCCCCCCCCCCCCEECCCCCCCEEEEECHHHCC
FEEPEKANKKVHFDNLTPLYPEQRLKMESRDPTKKDRSGRVIDIVSPIGKGQRALIVAPP
CCCCHHCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECC
RTGKTVLMQNIAAAIEENHPECYLIVLLIDERPEEVTDMRRTVKGEVVASTFDEPATRHV
CCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCCCCHHHHH
QVAEMVIEKAKRLVEHKRDVVILLDSITRLGRAYNTTVPSSGKVLTGGVDANALQRPKRF
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHH
FGAARNVENGGSLTIVATALIDTGSRMDEVIFEEFKGTGNSEVVLDRKIADKRTFPAIDI
HHHHCCCCCCCCEEEEEEEEHHCCCHHHHHHHHHHCCCCCCEEEEECHHHCCCCCCHHHH
MKSGTRKEELITPHDQLSKIYILRRILGPMGANDAVDFLLDKLKQTKTNDEFFEAMKN
HHCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure 
TLRELKAKSPEELLAYAEELEVENASSMRTQDMLFAILKELADSEVEITGQGVLEVLTD
CHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHC
GFGFLRSPESNYLPGPDDIYVSPEVLKKANIRTGDTVEGPIVAPQDSERYFALTDVSQIN
CHHHHCCCCCCCCCCCCCEEECHHHHHHCCCCCCCCCCCCEECCCCCCCEEEEECHHHCC
FEEPEKANKKVHFDNLTPLYPEQRLKMESRDPTKKDRSGRVIDIVSPIGKGQRALIVAPP
CCCCHHCCCEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEECC
RTGKTVLMQNIAAAIEENHPECYLIVLLIDERPEEVTDMRRTVKGEVVASTFDEPATRHV
CCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCCCCHHHHH
QVAEMVIEKAKRLVEHKRDVVILLDSITRLGRAYNTTVPSSGKVLTGGVDANALQRPKRF
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHH
FGAARNVENGGSLTIVATALIDTGSRMDEVIFEEFKGTGNSEVVLDRKIADKRTFPAIDI
HHHHCCCCCCCCEEEEEEEEHHCCCHHHHHHHHHHCCCCCCEEEEECHHHCCCCCCHHHH
MKSGTRKEELITPHDQLSKIYILRRILGPMGANDAVDFLLDKLKQTKTNDEFFEAMKN
HHCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8606169 [H]