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The map label for this gene is ydeN [H]

Identifier: 114798452

GI number: 114798452

Start: 1709033

End: 1710559

Strand: Reverse

Name: ydeN [H]

Synonym: HNE_1667

Alternate gene names: 114798452

Gene position: 1710559-1709033 (Counterclockwise)

Preceding gene: 114797882

Following gene: 114797695

Centisome position: 46.17

GC content: 60.97

Gene sequence:

>1527_bases
GTGGAATGGATGCAGGGACCAGAGACGGCCGGTCCGGCGCAGGCTGTCCGCCCGCCCAATGTCATCTTCATCCTGGCCGA
TGATCTCGGCATAAACGACATCTCCACCTTCGGCGGTGGCATGGCCGACGGGCGCGTACAAACGCCCAACATCGACCGCC
TCGCCGCAGAAGGCGCCCTGTTCTCCACCGCGTATTCCGGCACAGGCACCTGCGCGCCCTCCCGTGCCATGCTCATGACC
GGCCGCTATCCCACGCGCACCGGCTTTGAGTACACCCCCACCCCACCGGGCATGTCCCGCATCGTGCCGATGTTTGCCAA
CGATATGAAAACCGGCCTTCCGCCAACGGAACAGGTCAAGGAAAACGAAAAGCTGATGCCGCCCTTCGCCGAACAGGGCC
TTCCAACAGAAGAAGTCACCCTTGCCGAAGTGCTGAAAGATCGCGGCTACCACACCGTCCATATCGGCAAATGGCATCTG
GGCAACACCAGCCCCTTCCGGCCAAACGATCAGGGCTTTGATGAAAGCCTCGACATGGCCAGCGGCCTGTTCCTGCCGCC
CGGCGATCCCCGCGGCGTCGAAGCCAGGCTGGACTTTGACCCCATCGACAAATTCCTCTGGGCACGCATGGATTTCGCCG
CCAGCTACAATGGCAGCGACTGGTTCGAGCCGGGCGGTTACCTCACCGATTACTGGACTGACGAATCCCTCAAGGTCATT
GACGCCAACAAGAACCGTCCCTTCTTCCTCTATCTCGCCCATTGGGGCGTCCACACGCCGCTTCAGGCCACAAAGGAAGA
CTATGAAGCTGTCGGCGACATTGAGCCCCATCGCCTGCGCGTCTACGCCGCCATGCTGCGCGCGGTAGACCGCAGCGTTG
GCCGCATTATGGAAAAACTCGAAGAAGAAGGTCTCGCCGACAACACCATCATCGTCTTCTCCAGCGATAATGGCGGCGCG
GGCTATATCGGCATTCCCGAAGTCAACGCGCCCTATCGCGGCTGGAAGATCACTCTGTTTGAAGGCGGCATCCGCGTACC
CCTCTTCATGAAATGGCCCGGCACCATCCAGCCCGGCACCGTGATCGACGAACCTGTCGCACATATCGACCTGATGCCGA
CCCTTGCTGCCGCCACCGGCGCGCGCCTCCCCTCAAGCGTCGAGATTGATGGCCAGAACCTCCTGCCGCTGGCAACCGGC
ACCGGACCCATCACCCGCCCGGATGACGCGCTCTTCTGGTCCAGCGGCTATTACAAAGTCGTGCGCGCTGGCGGCTGGAA
ACTTCAGGTCAACGGCCGCCAGCAAAAAAGCTGGCTGTTCAATCTGAACGAAGACCCCACCGAACAGACAAACCTTGCCG
CGTCCGAGCCCGAGAAGCTGGCAGAACTGCAAGCCCTTATCGACGCGCACTGGAAAGACGCACGCGAACCGCTCTATCCC
TATACAATCGAAAGCCCGATCAAGATCGACCACACCATCGACGCGCCGTATGTCGAAGGCGAGGAATACGTCTACTGGCC
CAATTGA

Upstream 100 bases:

>100_bases
TGTCGTTGCCGCTGCTGCAATCGCCTTCTTCAACCGCAAGGAAATCATCCTTTACCTCGTCACCAATGCCGACCGCCCCA
CGGTCGCGCCAAACCGCCCT

Downstream 100 bases:

>100_bases
CCCGGCCTATTCGGCTTCCAGCTCTTTCACGATCCGGAAGCCGATATGGTTGGAGGAGAAATCAATCTCCTGCGGGTGGC
GCGCCGCGGGCCGGTAACGC

Product: sulfatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MEWMQGPETAGPAQAVRPPNVIFILADDLGINDISTFGGGMADGRVQTPNIDRLAAEGALFSTAYSGTGTCAPSRAMLMT
GRYPTRTGFEYTPTPPGMSRIVPMFANDMKTGLPPTEQVKENEKLMPPFAEQGLPTEEVTLAEVLKDRGYHTVHIGKWHL
GNTSPFRPNDQGFDESLDMASGLFLPPGDPRGVEARLDFDPIDKFLWARMDFAASYNGSDWFEPGGYLTDYWTDESLKVI
DANKNRPFFLYLAHWGVHTPLQATKEDYEAVGDIEPHRLRVYAAMLRAVDRSVGRIMEKLEEEGLADNTIIVFSSDNGGA
GYIGIPEVNAPYRGWKITLFEGGIRVPLFMKWPGTIQPGTVIDEPVAHIDLMPTLAAATGARLPSSVEIDGQNLLPLATG
TGPITRPDDALFWSSGYYKVVRAGGWKLQVNGRQQKSWLFNLNEDPTEQTNLAASEPEKLAELQALIDAHWKDAREPLYP
YTIESPIKIDHTIDAPYVEGEEYVYWPN

Sequences:

>Translated_508_residues
MEWMQGPETAGPAQAVRPPNVIFILADDLGINDISTFGGGMADGRVQTPNIDRLAAEGALFSTAYSGTGTCAPSRAMLMT
GRYPTRTGFEYTPTPPGMSRIVPMFANDMKTGLPPTEQVKENEKLMPPFAEQGLPTEEVTLAEVLKDRGYHTVHIGKWHL
GNTSPFRPNDQGFDESLDMASGLFLPPGDPRGVEARLDFDPIDKFLWARMDFAASYNGSDWFEPGGYLTDYWTDESLKVI
DANKNRPFFLYLAHWGVHTPLQATKEDYEAVGDIEPHRLRVYAAMLRAVDRSVGRIMEKLEEEGLADNTIIVFSSDNGGA
GYIGIPEVNAPYRGWKITLFEGGIRVPLFMKWPGTIQPGTVIDEPVAHIDLMPTLAAATGARLPSSVEIDGQNLLPLATG
TGPITRPDDALFWSSGYYKVVRAGGWKLQVNGRQQKSWLFNLNEDPTEQTNLAASEPEKLAELQALIDAHWKDAREPLYP
YTIESPIKIDHTIDAPYVEGEEYVYWPN
>Mature_508_residues
MEWMQGPETAGPAQAVRPPNVIFILADDLGINDISTFGGGMADGRVQTPNIDRLAAEGALFSTAYSGTGTCAPSRAMLMT
GRYPTRTGFEYTPTPPGMSRIVPMFANDMKTGLPPTEQVKENEKLMPPFAEQGLPTEEVTLAEVLKDRGYHTVHIGKWHL
GNTSPFRPNDQGFDESLDMASGLFLPPGDPRGVEARLDFDPIDKFLWARMDFAASYNGSDWFEPGGYLTDYWTDESLKVI
DANKNRPFFLYLAHWGVHTPLQATKEDYEAVGDIEPHRLRVYAAMLRAVDRSVGRIMEKLEEEGLADNTIIVFSSDNGGA
GYIGIPEVNAPYRGWKITLFEGGIRVPLFMKWPGTIQPGTVIDEPVAHIDLMPTLAAATGARLPSSVEIDGQNLLPLATG
TGPITRPDDALFWSSGYYKVVRAGGWKLQVNGRQQKSWLFNLNEDPTEQTNLAASEPEKLAELQALIDAHWKDAREPLYP
YTIESPIKIDHTIDAPYVEGEEYVYWPN

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4503899, Length=403, Percent_Identity=33.4987593052109, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI146229331, Length=476, Percent_Identity=32.9831932773109, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI146229329, Length=476, Percent_Identity=32.9831932773109, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI6005990, Length=476, Percent_Identity=32.9831932773109, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI146229324, Length=476, Percent_Identity=32.9831932773109, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI38569405, Length=523, Percent_Identity=28.2982791586998, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI157266309, Length=567, Percent_Identity=27.8659611992945, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI109389362, Length=524, Percent_Identity=28.0534351145038, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI59797060, Length=513, Percent_Identity=27.8752436647173, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI38569407, Length=381, Percent_Identity=32.2834645669291, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI53831991, Length=496, Percent_Identity=28.8306451612903, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI71852584, Length=445, Percent_Identity=26.9662921348315, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI45430057, Length=403, Percent_Identity=29.0322580645161, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI146229327, Length=368, Percent_Identity=32.8804347826087, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI58743319, Length=172, Percent_Identity=33.7209302325581, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI31742482, Length=291, Percent_Identity=26.1168384879725, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI71852586, Length=204, Percent_Identity=31.8627450980392, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI39930577, Length=232, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081924, Length=530, Percent_Identity=26.0377358490566, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790233, Length=520, Percent_Identity=27.8846153846154, Blast_Score=142, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI115533416, Length=486, Percent_Identity=30.2469135802469, Blast_Score=181, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI115533418, Length=476, Percent_Identity=29.6218487394958, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17559078, Length=261, Percent_Identity=27.2030651340996, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24666175, Length=398, Percent_Identity=33.4170854271357, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24666109, Length=400, Percent_Identity=32.75, Blast_Score=169, Evalue=4e-42,
Organism=Drosophila melanogaster, GI281366397, Length=396, Percent_Identity=31.8181818181818, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281366395, Length=396, Percent_Identity=31.8181818181818, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24666163, Length=396, Percent_Identity=31.8181818181818, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281363223, Length=392, Percent_Identity=33.6734693877551, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24647401, Length=483, Percent_Identity=23.8095238095238, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI21356831, Length=162, Percent_Identity=27.1604938271605, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 56257; Mature: 56257

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWMQGPETAGPAQAVRPPNVIFILADDLGINDISTFGGGMADGRVQTPNIDRLAAEGAL
CCCCCCCCCCCCCHHCCCCCEEEEEECCCCCCHHHHCCCCCCCCEEECCCHHHHHHCCCE
FSTAYSGTGTCAPSRAMLMTGRYPTRTGFEYTPTPPGMSRIVPMFANDMKTGLPPTEQVK
EEEECCCCCCCCCCCEEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHH
ENEKLMPPFAEQGLPTEEVTLAEVLKDRGYHTVHIGKWHLGNTSPFRPNDQGFDESLDMA
CCCCCCCCHHHCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHH
SGLFLPPGDPRGVEARLDFDPIDKFLWARMDFAASYNGSDWFEPGGYLTDYWTDESLKVI
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEE
DANKNRPFFLYLAHWGVHTPLQATKEDYEAVGDIEPHRLRVYAAMLRAVDRSVGRIMEKL
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEEGLADNTIIVFSSDNGGAGYIGIPEVNAPYRGWKITLFEGGIRVPLFMKWPGTIQPGT
HHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCC
VIDEPVAHIDLMPTLAAATGARLPSSVEIDGQNLLPLATGTGPITRPDDALFWSSGYYKV
CCCCCHHHEEHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCCCCCCEEECCCCEEE
VRAGGWKLQVNGRQQKSWLFNLNEDPTEQTNLAASEPEKLAELQALIDAHWKDAREPLYP
EECCCEEEEECCCCCCEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
YTIESPIKIDHTIDAPYVEGEEYVYWPN
EECCCCEEEEEECCCCEECCCEEEECCC
>Mature Secondary Structure
MEWMQGPETAGPAQAVRPPNVIFILADDLGINDISTFGGGMADGRVQTPNIDRLAAEGAL
CCCCCCCCCCCCCHHCCCCCEEEEEECCCCCCHHHHCCCCCCCCEEECCCHHHHHHCCCE
FSTAYSGTGTCAPSRAMLMTGRYPTRTGFEYTPTPPGMSRIVPMFANDMKTGLPPTEQVK
EEEECCCCCCCCCCCEEEEECCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHH
ENEKLMPPFAEQGLPTEEVTLAEVLKDRGYHTVHIGKWHLGNTSPFRPNDQGFDESLDMA
CCCCCCCCHHHCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCCCCCCHHHHHH
SGLFLPPGDPRGVEARLDFDPIDKFLWARMDFAASYNGSDWFEPGGYLTDYWTDESLKVI
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEE
DANKNRPFFLYLAHWGVHTPLQATKEDYEAVGDIEPHRLRVYAAMLRAVDRSVGRIMEKL
ECCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EEEGLADNTIIVFSSDNGGAGYIGIPEVNAPYRGWKITLFEGGIRVPLFMKWPGTIQPGT
HHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCCCC
VIDEPVAHIDLMPTLAAATGARLPSSVEIDGQNLLPLATGTGPITRPDDALFWSSGYYKV
CCCCCHHHEEHHHHHHHHHCCCCCCEEEECCCCEEEEECCCCCCCCCCCCEEECCCCEEE
VRAGGWKLQVNGRQQKSWLFNLNEDPTEQTNLAASEPEKLAELQALIDAHWKDAREPLYP
EECCCEEEEECCCCCCEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
YTIESPIKIDHTIDAPYVEGEEYVYWPN
EECCCCEEEEEECCCCEECCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]