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The map label for this gene is atsA [H]

Identifier: 114797882

GI number: 114797882

Start: 1710684

End: 1712465

Strand: Reverse

Name: atsA [H]

Synonym: HNE_1668

Alternate gene names: 114797882

Gene position: 1712465-1710684 (Counterclockwise)

Preceding gene: 114798166

Following gene: 114798452

Centisome position: 46.22

GC content: 63.02

Gene sequence:

>1782_bases
ATGAAGCTCAGGCTTCTCGCCGCCTTGGCGGCTCTTACGGCCATTGCGGCCCCGGCTCTCCCGCAGGCATCACCCGAAAA
ACCCAATATCGTGATCCTGCTGATCGATGATGGCGCGCTGATGGACCTCGGCATCTATGGCGGCGAAGCGGCCACACCCA
ACATCGACGCGCTCGCGGGCGCCGGCGCCATGTTCACGCAATACCGCTCCTCACCGCTCTGCTCCCCCTCCCGCGCCATG
CTGCTCACCGGCATCGACAACCACCGCACCGGCATCTCCACCATTCCCGAAGTCCTCCCCCCGGAACATGTCGGCCAGCC
GGGCTACACGATGAGCCTCGAGCCCGGCGTCACCACCCTCGCCGCCCGCCTCAAGCCGCTGGGCTACCGTACCCTGATGA
CCGGCAAATGGCATCTTGGCAGCGGCGAAGGCGACCTGCCCGACAGCCACGGCTTTGTCCGCTCCTTCGCGCTGGACGCT
TCGGGGGCGGACAATTGGGAAGACAAATCCTACATGCCCTTCTATGCCGACGCGCCCTGGTATGAAGATGGGCAGGCAGC
TGCTCTGCCGGAAGATTTCTATTCCTCCACCTTCATCGTCGACAAGATGATCGAATATATGGACGAGGACACGAACCGCG
CGCCCTTCCTCGCCTATCTCGGCTTCCAGGCGCTCCACATCCCGGTGCAAGCCCCCCCGGAATTCACCGCCAATTATCTC
GATACCTACAGCGATGGCTGGGAAGCCCTGCAAACCCGCCGCTGGAAACGCGCTCAGGAAATCGGCCTCGTGCCTGAGGG
CGCCGCGCAACCCGCGCTCCACCCGGACCTGCGCAAATGGGATGGCCTGCCCGAGGACAAACAACGCCTCTTCGCCGCCC
GCATGGCCGTCAATGCCGGCATGCTTGAAGCGATGGACCATCATGTCGGCCGCCTGATCGACCACCTCAAAACCAACGGC
ACCTACGACAACACCGTCTTCGTCATCACCTCCGATAACGGCCCGGAGCCGTCCTCCGCCGAAGATCCCCGCTTTGAAAC
CTGGCTTAGCGCCAATGGCTATCATGTCGGCATCGAAGGCATCGGCGAGAAGGGCAGTTATGGTTTCATCGGTCCCGAAT
TTGCCAGCGCCGCGTCCTCGCCAAGCTACCTGTTCAAATTCTACGTCTCTGAAGGCGGCCTCCGCGTACCTCTCATCATG
GCCGGCCCCGGCATAGCGCCCGGCCGGGTGGATGCCTTCGCGATGGTCACAGATGTGACGCCCACCCTGCTCGAAATGGT
CAACGCCGGTCCTGCCCCGGAAGGCGCCGTCACGCTGGATGGCCGCAGCCTTCTACCGGTCCTCTCCGGCGCGGCGCCTA
CCGTCTATAGCGACGAGGATGCCATCGGCATCGAAGTGTCCGGCAATGCCGCCCTCTACAAAGGCCCGTGGAAGATCACC
CGCAACCTCACCCCCTGGGGCGATGGCCAATGGCGCTTGTTCAATCTCGAAACCGATCCCGGCGAGACGCAGGATTTGAG
CGCCGCCAATGCCGCCCTGTTCGAACAGATGCAGGCCGATTACGCCGCCTATGCCGCCCGCGTCGGCGTGCTGGAGGTGC
CTTCAGGCTACGATTCCGTTGCCCAAGTCGAAAAGAACATGACCGCCGCCGTCCTGAAACGCGCTATGCCAAAGATCATC
GCCTTCAGCATCGGTGGCCTCCTGCTCCTCGGCGGGCTCGTCTGGCTGATCTACAACATTCTCCGCAACCGGAAGAAAAA
GGCCCAAGGCAATGCTGCGTAA

Upstream 100 bases:

>100_bases
CTTTCCGGCTGGCAGGCAAGCAGACGCTCAGGATTCAATTGACGCGGATCGTGCCATAATGTTTGATGGTGAAAATAAAA
CGATCCGGGAGGGTTCCACC

Downstream 100 bases:

>100_bases
GATCCTAATTGGCGTCCTCCTTGTTGTCGTTGCCGCTGCTGCAATCGCCTTCTTCAACCGCAAGGAAATCATCCTTTACC
TCGTCACCAATGCCGACCGC

Product: sulfatase family protein

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MKLRLLAALAALTAIAAPALPQASPEKPNIVILLIDDGALMDLGIYGGEAATPNIDALAGAGAMFTQYRSSPLCSPSRAM
LLTGIDNHRTGISTIPEVLPPEHVGQPGYTMSLEPGVTTLAARLKPLGYRTLMTGKWHLGSGEGDLPDSHGFVRSFALDA
SGADNWEDKSYMPFYADAPWYEDGQAAALPEDFYSSTFIVDKMIEYMDEDTNRAPFLAYLGFQALHIPVQAPPEFTANYL
DTYSDGWEALQTRRWKRAQEIGLVPEGAAQPALHPDLRKWDGLPEDKQRLFAARMAVNAGMLEAMDHHVGRLIDHLKTNG
TYDNTVFVITSDNGPEPSSAEDPRFETWLSANGYHVGIEGIGEKGSYGFIGPEFASAASSPSYLFKFYVSEGGLRVPLIM
AGPGIAPGRVDAFAMVTDVTPTLLEMVNAGPAPEGAVTLDGRSLLPVLSGAAPTVYSDEDAIGIEVSGNAALYKGPWKIT
RNLTPWGDGQWRLFNLETDPGETQDLSAANAALFEQMQADYAAYAARVGVLEVPSGYDSVAQVEKNMTAAVLKRAMPKII
AFSIGGLLLLGGLVWLIYNILRNRKKKAQGNAA

Sequences:

>Translated_593_residues
MKLRLLAALAALTAIAAPALPQASPEKPNIVILLIDDGALMDLGIYGGEAATPNIDALAGAGAMFTQYRSSPLCSPSRAM
LLTGIDNHRTGISTIPEVLPPEHVGQPGYTMSLEPGVTTLAARLKPLGYRTLMTGKWHLGSGEGDLPDSHGFVRSFALDA
SGADNWEDKSYMPFYADAPWYEDGQAAALPEDFYSSTFIVDKMIEYMDEDTNRAPFLAYLGFQALHIPVQAPPEFTANYL
DTYSDGWEALQTRRWKRAQEIGLVPEGAAQPALHPDLRKWDGLPEDKQRLFAARMAVNAGMLEAMDHHVGRLIDHLKTNG
TYDNTVFVITSDNGPEPSSAEDPRFETWLSANGYHVGIEGIGEKGSYGFIGPEFASAASSPSYLFKFYVSEGGLRVPLIM
AGPGIAPGRVDAFAMVTDVTPTLLEMVNAGPAPEGAVTLDGRSLLPVLSGAAPTVYSDEDAIGIEVSGNAALYKGPWKIT
RNLTPWGDGQWRLFNLETDPGETQDLSAANAALFEQMQADYAAYAARVGVLEVPSGYDSVAQVEKNMTAAVLKRAMPKII
AFSIGGLLLLGGLVWLIYNILRNRKKKAQGNAA
>Mature_593_residues
MKLRLLAALAALTAIAAPALPQASPEKPNIVILLIDDGALMDLGIYGGEAATPNIDALAGAGAMFTQYRSSPLCSPSRAM
LLTGIDNHRTGISTIPEVLPPEHVGQPGYTMSLEPGVTTLAARLKPLGYRTLMTGKWHLGSGEGDLPDSHGFVRSFALDA
SGADNWEDKSYMPFYADAPWYEDGQAAALPEDFYSSTFIVDKMIEYMDEDTNRAPFLAYLGFQALHIPVQAPPEFTANYL
DTYSDGWEALQTRRWKRAQEIGLVPEGAAQPALHPDLRKWDGLPEDKQRLFAARMAVNAGMLEAMDHHVGRLIDHLKTNG
TYDNTVFVITSDNGPEPSSAEDPRFETWLSANGYHVGIEGIGEKGSYGFIGPEFASAASSPSYLFKFYVSEGGLRVPLIM
AGPGIAPGRVDAFAMVTDVTPTLLEMVNAGPAPEGAVTLDGRSLLPVLSGAAPTVYSDEDAIGIEVSGNAALYKGPWKIT
RNLTPWGDGQWRLFNLETDPGETQDLSAANAALFEQMQADYAAYAARVGVLEVPSGYDSVAQVEKNMTAAVLKRAMPKII
AFSIGGLLLLGGLVWLIYNILRNRKKKAQGNAA

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI38569407, Length=326, Percent_Identity=27.6073619631902, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI38569405, Length=314, Percent_Identity=28.0254777070064, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI109389362, Length=327, Percent_Identity=25.9938837920489, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI59797060, Length=542, Percent_Identity=24.3542435424354, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4503899, Length=225, Percent_Identity=32, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI146229331, Length=431, Percent_Identity=30.1624129930394, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI146229329, Length=431, Percent_Identity=30.1624129930394, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI6005990, Length=431, Percent_Identity=30.1624129930394, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI146229324, Length=431, Percent_Identity=30.1624129930394, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI157266309, Length=154, Percent_Identity=39.6103896103896, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI31742482, Length=154, Percent_Identity=37.6623376623377, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI58743319, Length=591, Percent_Identity=23.6886632825719, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI71852586, Length=138, Percent_Identity=39.1304347826087, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI53831991, Length=137, Percent_Identity=38.6861313868613, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI71852584, Length=138, Percent_Identity=39.1304347826087, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI45430057, Length=230, Percent_Identity=30.4347826086957, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790233, Length=562, Percent_Identity=25.9786476868327, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790112, Length=328, Percent_Identity=25.9146341463415, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533416, Length=524, Percent_Identity=24.4274809160305, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17559078, Length=226, Percent_Identity=30.9734513274336, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363223, Length=497, Percent_Identity=26.3581488933602, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24666175, Length=339, Percent_Identity=26.5486725663717, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24666109, Length=490, Percent_Identity=25.5102040816327, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281366397, Length=335, Percent_Identity=26.865671641791, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281366395, Length=335, Percent_Identity=26.865671641791, Blast_Score=83, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24666163, Length=335, Percent_Identity=26.865671641791, Blast_Score=83, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 63800; Mature: 63800

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRLLAALAALTAIAAPALPQASPEKPNIVILLIDDGALMDLGIYGGEAATPNIDALAG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHC
AGAMFTQYRSSPLCSPSRAMLLTGIDNHRTGISTIPEVLPPEHVGQPGYTMSLEPGVTTL
CCHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCHHHCCCCCEEEEECCCHHHH
AARLKPLGYRTLMTGKWHLGSGEGDLPDSHGFVRSFALDASGADNWEDKSYMPFYADAPW
HHHHCCCCCEEEEECEEECCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCCCEECCCCC
YEDGQAAALPEDFYSSTFIVDKMIEYMDEDTNRAPFLAYLGFQALHIPVQAPPEFTANYL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCHHHHHHH
DTYSDGWEALQTRRWKRAQEIGLVPEGAAQPALHPDLRKWDGLPEDKQRLFAARMAVNAG
HHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
MLEAMDHHVGRLIDHLKTNGTYDNTVFVITSDNGPEPSSAEDPRFETWLSANGYHVGIEG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCEEEEEEE
IGEKGSYGFIGPEFASAASSPSYLFKFYVSEGGLRVPLIMAGPGIAPGRVDAFAMVTDVT
CCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCEEEECCCC
PTLLEMVNAGPAPEGAVTLDGRSLLPVLSGAAPTVYSDEDAIGIEVSGNAALYKGPWKIT
HHHHHHHHCCCCCCCCEEECCCCHHHHHCCCCCCEECCCCCEEEEECCCEEEEECCEEEE
RNLTPWGDGQWRLFNLETDPGETQDLSAANAALFEQMQADYAAYAARVGVLEVPSGYDSV
CCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHH
AQVEKNMTAAVLKRAMPKIIAFSIGGLLLLGGLVWLIYNILRNRKKKAQGNAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKLRLLAALAALTAIAAPALPQASPEKPNIVILLIDDGALMDLGIYGGEAATPNIDALAG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHC
AGAMFTQYRSSPLCSPSRAMLLTGIDNHRTGISTIPEVLPPEHVGQPGYTMSLEPGVTTL
CCHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCHHHCCCCCEEEEECCCHHHH
AARLKPLGYRTLMTGKWHLGSGEGDLPDSHGFVRSFALDASGADNWEDKSYMPFYADAPW
HHHHCCCCCEEEEECEEECCCCCCCCCCCCCHHHHEEECCCCCCCCCCCCCCCEECCCCC
YEDGQAAALPEDFYSSTFIVDKMIEYMDEDTNRAPFLAYLGFQALHIPVQAPPEFTANYL
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEECCCCCCHHHHHHH
DTYSDGWEALQTRRWKRAQEIGLVPEGAAQPALHPDLRKWDGLPEDKQRLFAARMAVNAG
HHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
MLEAMDHHVGRLIDHLKTNGTYDNTVFVITSDNGPEPSSAEDPRFETWLSANGYHVGIEG
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEECCCCEEEEEEE
IGEKGSYGFIGPEFASAASSPSYLFKFYVSEGGLRVPLIMAGPGIAPGRVDAFAMVTDVT
CCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCEEEECCCC
PTLLEMVNAGPAPEGAVTLDGRSLLPVLSGAAPTVYSDEDAIGIEVSGNAALYKGPWKIT
HHHHHHHHCCCCCCCCEEECCCCHHHHHCCCCCCEECCCCCEEEEECCCEEEEECCEEEE
RNLTPWGDGQWRLFNLETDPGETQDLSAANAALFEQMQADYAAYAARVGVLEVPSGYDSV
CCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHH
AQVEKNMTAAVLKRAMPKIIAFSIGGLLLLGGLVWLIYNILRNRKKKAQGNAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7744061; 10984043 [H]