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The map label for this gene is csd [H]

Identifier: 114798416

GI number: 114798416

Start: 2744432

End: 2745688

Strand: Direct

Name: csd [H]

Synonym: HNE_2588

Alternate gene names: 114798416

Gene position: 2744432-2745688 (Clockwise)

Preceding gene: 114800525

Following gene: 114800437

Centisome position: 74.07

GC content: 61.18

Gene sequence:

>1257_bases
ATGTCTCAGATCACCCGTCGCAACTGGCTGGCCCTTGGCGCCGCAACGCTCGCCGGAGCCGCTGCCTGCCGCAGTCCGGC
TGCTGCCAGTCCTGCCGCGTCTGTCTCGCCTACCGCGGGCAACTTGCCAGATCGCACGAGCTTCAATCTTGGCTCCTCTG
TCTATCTGAATGCCGGATCGCAGCACCCAATCAGCCGCCCGGCCCGCGCGTCCATTGACGCCTATCTCGACCACCGCGCC
GATCACGCCCCTGGCAGTGATTATGAACTCGGCAGCAGCAACATCATCGAAAAGTTCGCCCGACTCGTAAACGCCGATCC
GGACGAAATCACGTTCGTGCAAAGCACCACGGCCGGAGAGCAGATGATCGTCCGCTCGCTGAAGCTTCCTGCATCCGGCG
CGCGGATTGTCACCGATACGCTCCACTTCTTCGGCTCAATGCCGATGTATGGAGAATTGGCCAAAGCTGGCTGCGATGTC
GCCTGGGTGAAACACCGCGACGGCCGCATCTCTCTGGAAGACATGGACCGCGCGATCACACCGGGAACGCGGCTTGTCGC
GCTGTCGCTCGTCTCCACGGTCAATGGATTCCAGCATGATCTGAAGGCTATCTGCGACCTTGCCCATTCGCGCGGCGCGC
TGGTGTATGCCGACATCATCCATGCAGCCGGCTGCATTCCGGTCGACCTCCATGCCAGCGGTGTCGATTTTGCTGCCTGC
GCCAGTTACAAATGGCTGATGGGCGATTTTGGCCTCGGCTTTCTTTATGTCCGCAAAGGCGCGCGCGACGCCCTGACGCG
GACGCAATACGGCTATTATGGCGTCAGCCGCTTCACCAGCCATGTCTACCCCTTCGATCCTCCGGGAGACGACGTGGCAA
GCTACGCTTTCGAAGACACGGCCACAGGACTGTTCGCACTGGGAACATATTCCCACACCACGATTTCGCTGCTCAACGCC
TCGCTTGACTATATCGCCAGCCTGGGCGTTGAAGCCATTCAGCGACACGCCATCACGCTCACATCGCGTCTCAAGGAAGG
CCTGAAGACCCAGGGATATGAGCTGATGACGCCGGAAGAAAGCCAGACACCGCTTGTCGCCTGCGTCTATCAGGACGCGC
GCACGCGGCTCGGCCCAAAGCTGAAGGCGGCCGGCATCACGACCACCGTATCAGCTCACCGCTTCCGCCCGTCCGTCTCC
GTGTTCAACACGATGGATGATATCGAGCTGTTTCTGGCCGCCATTGGCCCGGCCTGA

Upstream 100 bases:

>100_bases
TGCATAATCGCGCCGAGGAATGCATGATCCATTCTCGCCGCGCCGCTATAATGGAAATATGGATCAAGCCGGACTTCAAG
CGTCCGGGGCGGAGAAACAC

Downstream 100 bases:

>100_bases
AGTTCTACTTTTCCAGAAAATCTCGCAGGTCGCTGGAAAACGCTTCAGAGGTTCCGCCCAGATAAAGCATGTGACCGGAG
GCATAGTCCGTAAACGTCAC

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSQITRRNWLALGAATLAGAAACRSPAAASPAASVSPTAGNLPDRTSFNLGSSVYLNAGSQHPISRPARASIDAYLDHRA
DHAPGSDYELGSSNIIEKFARLVNADPDEITFVQSTTAGEQMIVRSLKLPASGARIVTDTLHFFGSMPMYGELAKAGCDV
AWVKHRDGRISLEDMDRAITPGTRLVALSLVSTVNGFQHDLKAICDLAHSRGALVYADIIHAAGCIPVDLHASGVDFAAC
ASYKWLMGDFGLGFLYVRKGARDALTRTQYGYYGVSRFTSHVYPFDPPGDDVASYAFEDTATGLFALGTYSHTTISLLNA
SLDYIASLGVEAIQRHAITLTSRLKEGLKTQGYELMTPEESQTPLVACVYQDARTRLGPKLKAAGITTTVSAHRFRPSVS
VFNTMDDIELFLAAIGPA

Sequences:

>Translated_418_residues
MSQITRRNWLALGAATLAGAAACRSPAAASPAASVSPTAGNLPDRTSFNLGSSVYLNAGSQHPISRPARASIDAYLDHRA
DHAPGSDYELGSSNIIEKFARLVNADPDEITFVQSTTAGEQMIVRSLKLPASGARIVTDTLHFFGSMPMYGELAKAGCDV
AWVKHRDGRISLEDMDRAITPGTRLVALSLVSTVNGFQHDLKAICDLAHSRGALVYADIIHAAGCIPVDLHASGVDFAAC
ASYKWLMGDFGLGFLYVRKGARDALTRTQYGYYGVSRFTSHVYPFDPPGDDVASYAFEDTATGLFALGTYSHTTISLLNA
SLDYIASLGVEAIQRHAITLTSRLKEGLKTQGYELMTPEESQTPLVACVYQDARTRLGPKLKAAGITTTVSAHRFRPSVS
VFNTMDDIELFLAAIGPA
>Mature_417_residues
SQITRRNWLALGAATLAGAAACRSPAAASPAASVSPTAGNLPDRTSFNLGSSVYLNAGSQHPISRPARASIDAYLDHRAD
HAPGSDYELGSSNIIEKFARLVNADPDEITFVQSTTAGEQMIVRSLKLPASGARIVTDTLHFFGSMPMYGELAKAGCDVA
WVKHRDGRISLEDMDRAITPGTRLVALSLVSTVNGFQHDLKAICDLAHSRGALVYADIIHAAGCIPVDLHASGVDFAACA
SYKWLMGDFGLGFLYVRKGARDALTRTQYGYYGVSRFTSHVYPFDPPGDDVASYAFEDTATGLFALGTYSHTTISLLNAS
LDYIASLGVEAIQRHAITLTSRLKEGLKTQGYELMTPEESQTPLVACVYQDARTRLGPKLKAAGITTTVSAHRFRPSVSV
FNTMDDIELFLAAIGPA

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=197, Percent_Identity=24.3654822335025, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787970, Length=273, Percent_Identity=25.6410256410256, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI48994898, Length=177, Percent_Identity=27.1186440677966, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25143064, Length=189, Percent_Identity=25.3968253968254, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=188, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129463, Length=273, Percent_Identity=26.7399267399267, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44729; Mature: 44598

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQITRRNWLALGAATLAGAAACRSPAAASPAASVSPTAGNLPDRTSFNLGSSVYLNAGS
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
QHPISRPARASIDAYLDHRADHAPGSDYELGSSNIIEKFARLVNADPDEITFVQSTTAGE
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHH
QMIVRSLKLPASGARIVTDTLHFFGSMPMYGELAKAGCDVAWVKHRDGRISLEDMDRAIT
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCCEEEHHHHHHHCC
PGTRLVALSLVSTVNGFQHDLKAICDLAHSRGALVYADIIHAAGCIPVDLHASGVDFAAC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCEEEECCCCCCHHHH
ASYKWLMGDFGLGFLYVRKGARDALTRTQYGYYGVSRFTSHVYPFDPPGDDVASYAFEDT
HCCHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHH
ATGLFALGTYSHTTISLLNASLDYIASLGVEAIQRHAITLTSRLKEGLKTQGYELMTPEE
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
SQTPLVACVYQDARTRLGPKLKAAGITTTVSAHRFRPSVSVFNTMDDIELFLAAIGPA
CCCCEEEEEEHHHHHHCCCCEEECCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQITRRNWLALGAATLAGAAACRSPAAASPAASVSPTAGNLPDRTSFNLGSSVYLNAGS
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCC
QHPISRPARASIDAYLDHRADHAPGSDYELGSSNIIEKFARLVNADPDEITFVQSTTAGE
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHH
QMIVRSLKLPASGARIVTDTLHFFGSMPMYGELAKAGCDVAWVKHRDGRISLEDMDRAIT
HHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEEECCCCEEEHHHHHHHCC
PGTRLVALSLVSTVNGFQHDLKAICDLAHSRGALVYADIIHAAGCIPVDLHASGVDFAAC
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCEEEECCCCCCHHHH
ASYKWLMGDFGLGFLYVRKGARDALTRTQYGYYGVSRFTSHVYPFDPPGDDVASYAFEDT
HCCHHHHHCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHH
ATGLFALGTYSHTTISLLNASLDYIASLGVEAIQRHAITLTSRLKEGLKTQGYELMTPEE
CCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
SQTPLVACVYQDARTRLGPKLKAAGITTTVSAHRFRPSVSVFNTMDDIELFLAAIGPA
CCCCEEEEEEHHHHHHCCCCEEECCCEEEEHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]