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The map label for this gene is nuoA [H]

Identifier: 114798172

GI number: 114798172

Start: 1785466

End: 1785840

Strand: Direct

Name: nuoA [H]

Synonym: HNE_1742

Alternate gene names: 114798172

Gene position: 1785466-1785840 (Clockwise)

Preceding gene: 114800054

Following gene: 114799608

Centisome position: 48.19

GC content: 55.2

Gene sequence:

>375_bases
ATGACGGATGTTGAACGGCTCGCCCTCGACTATCTACCGGTCATCATCTTTCTGGTGATCGGTGCAGCGATTTCCGGTCT
TTTCGTGATCGGAAACGTGCTCCTGGCGCCCTCTAAGCCGGACCCGGAAAAGAATTCGGCCTATGAGTGCGGTTTCCCGG
CTTTCGATGATGCGCGCATGAAATTCGACGTGCGATTCTATCTCGTCGCCATTCTCTTCATCATTTTCGACCTCGAAGTC
GCTTTCCTGTTCCCGTGGGCCGTCAGCCTCGGTGAGATCGGTATTCTCGGTTTCTGGTCTATGGTGGGTTTCCTGGGCGT
CCTGACGGTCGGCTTTATCTATGAATGGCGCCGTGGCGCGCTGGAGTGGGAATAA

Upstream 100 bases:

>100_bases
CAGGATATACTGCGAGGCGCTGTGATTACAGTTGAGCGTCAGTTGCGCCGGGCGGGAAACCGTCCTAATCGGGCGGCAAC
GCAATGGGAGCAAATGCGCT

Downstream 100 bases:

>100_bases
TGTCTGACAACTCCTACAAGCCCTATGCGCTCGGTGCAGCGCGGGCAGGGGTCGATGGCGGGTTCAAGCCCGGCAATGAC
GATCCGTTTTATTCGGGTCT

Product: NADH-quinone oxidoreductase subunit A

Products: NA

Alternate protein names: NADH dehydrogenase I subunit A; NDH-1 subunit A; NUO1 [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MTDVERLALDYLPVIIFLVIGAAISGLFVIGNVLLAPSKPDPEKNSAYECGFPAFDDARMKFDVRFYLVAILFIIFDLEV
AFLFPWAVSLGEIGILGFWSMVGFLGVLTVGFIYEWRRGALEWE

Sequences:

>Translated_124_residues
MTDVERLALDYLPVIIFLVIGAAISGLFVIGNVLLAPSKPDPEKNSAYECGFPAFDDARMKFDVRFYLVAILFIIFDLEV
AFLFPWAVSLGEIGILGFWSMVGFLGVLTVGFIYEWRRGALEWE
>Mature_123_residues
TDVERLALDYLPVIIFLVIGAAISGLFVIGNVLLAPSKPDPEKNSAYECGFPAFDDARMKFDVRFYLVAILFIIFDLEVA
FLFPWAVSLGEIGILGFWSMVGFLGVLTVGFIYEWRRGALEWE

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788625, Length=123, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023043
- InterPro:   IPR000440 [H]

Pfam domain/function: PF00507 Oxidored_q4 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 13933; Mature: 13801

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVERLALDYLPVIIFLVIGAAISGLFVIGNVLLAPSKPDPEKNSAYECGFPAFDDARM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHH
KFDVRFYLVAILFIIFDLEVAFLFPWAVSLGEIGILGFWSMVGFLGVLTVGFIYEWRRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEWE
CCCC
>Mature Secondary Structure 
TDVERLALDYLPVIIFLVIGAAISGLFVIGNVLLAPSKPDPEKNSAYECGFPAFDDARM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHH
KFDVRFYLVAILFIIFDLEVAFLFPWAVSLGEIGILGFWSMVGFLGVLTVGFIYEWRRGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LEWE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA