Click here to switch to the map view.

The map label for this gene is pamO [H]

Identifier: 114798131

GI number: 114798131

Start: 1315931

End: 1317730

Strand: Reverse

Name: pamO [H]

Synonym: HNE_1286

Alternate gene names: 114798131

Gene position: 1317730-1315931 (Counterclockwise)

Preceding gene: 114798913

Following gene: 114800005

Centisome position: 35.57

GC content: 61.33

Gene sequence:

>1800_bases
ATGGCTGACAATGCGGCCCTTGATCTGGATTTTGACCCCAATGAGCTGCGCGACCGCTACCGCGCCGAGCGCGACAAGCG
CGTGCGCAAGGACGGGAACGAGCAGTATGTGAACGTCGCCGGACAGTTCGCGCACTATCTGGAAGATCCCTACTCGGAGC
GGATTGAGCGCGCGCCGGTGACCGATCATGTCGAAGTTGCGGTCATCGGCGGCGGCTTTGGCGGGCTGCTCTCGGCGGCG
CGCCTGCGCAAGGCGGGCTTCAAAGACATCCGCATGATCGAGACCGGCGGCGACTTCGGCGGCACCTGGTACTGGAACCG
CTATCCCGGCGCGGCCTGCGATATCGAGAGCTATATCTACCTGCCGCTGCTGGAAGAGACCGGCTACATTCCCAAAGAGA
AATACACCAAGGCGCCCGAGATCCTCGAACACTCCTCACGGATTGCCAAGCATTTCGGCCTCTATGAAAACGCCCTCCTC
GGCACCGGCGTGACGGGTATGAAATGGGACGAGGCCCGCAAGGTCTGGATCATCGAGACGGACCGGAATGATCGCTTCAC
GGCGCAGTTCGTCATCATGTCCAACGGCCCGCTGAACCGGCCGAAACTGCCTGGCATTCCCGGCGTTGAAAGCTTCAAGG
GTCACAGCTTCCACACCAGCCGCTGGGATTATGCCTATACCGGCGGGGACAGCACAGGCGGCCTCACCAAGCTGAAAGAT
AAGGTGGTCGGCATCATCGGCACCGGCGCCACCGCTGTGCAGTGCGTGCCCCATCTGGCTGCAGGCGCAAAGCAACTCTA
CGTCTTCCAGCGCACGCCTTCTTCCATCGATGTGCGCAATGACAAGCCGACCGATCCGGACTGGGCGAAAAGCCTGGAGC
CCGGCTGGCAGCGCCGCCGCATGGAGAATTTCAACACGCTGGTTTCCGGCGGCTATGAGCCGGAAGATCTGGTGCAGGAC
GGGTGGACGGACATTATCCGCAACATCCTCTTCCTCGCCAGTTCCGGCGACACGCAGGGCCTGACACCCGATCGGCTGGC
AGAGCTCGCCGAACTGGCCGATTACAAGAAGATGGAACAGGTGCGCGGACGCGTCGATGAGGTGGTCAAAGACCCCGACA
CCGCCGCCAAGCTGAAGCCCTGGTATCGCCAGTTCTGCAAACGGCCCTGTTTCCATGACGCTTACCTGAACTCCTTCAAC
CGCCCGACCGTGACGCTGGTGGATACCGGCGGCCAGGGCGTTGAGCGGATCACGGAAGATTCGATTATCGCCGATGGCGT
CGAATACAAGATCGATTGCCTCGTCTATGCCACCGGCTTTGAAGTGGGCACCGATTACACCCGCCGCGCCGGATACGATC
CTGTCGGCAAAGACGGCGTGACCATGAAAGATCATTGGGCGGACGGTATGCGCAGCCTGCATGGCCTTGCGGTCAATAAC
TTCCCCAACATGTTCCTGATGGGGCCGGGACAGGCAGGCTTCACCGCCAACTATCCCCACCTTCTGGACGAGCAGGCCGA
GCAGATCGCCTACATCCTCTCGGAAGTCTCCGCCCGTCAGGCCAGCACGTTTGAGGCAAGCCCGGAAGGCGAAGCCGCCT
GGGTTCAGAAGGTCATCGAGAAGGCCATGATGCGCCAGGAATTCCTCGAGGAATGCACGCCGGGCTATTACAACAATGAA
GGCAAGCCGAGCGACCGGGCCGCGCAGAACAACTCCTATGGCGAAGGCCCCAATGCCTATTTCCGCATCCTGAAAGCCTG
GCGCGAAAGCGGCGAGCTGAACGGGCTGGAACTGAGCTAG

Upstream 100 bases:

>100_bases
ACGGCTGTTAGGCGCCGTCAATCACGGTTAGATTCCTTCTCGAATGGACGAGATGCGACGGGCAAAGATCCCGCGCGCCG
CACCGAGGAGGAATGCAAAT

Downstream 100 bases:

>100_bases
GCTTTACTCTTCCACCAGCGAGACCAGCAGGTCGCCCTCGGCAACCTGCTGGCCGGCGCTGGAATGGATGGCCTCCACCA
CGCCGTCGCGCGGCGCGGCC

Product: cyclododecanone monooxygenase

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MADNAALDLDFDPNELRDRYRAERDKRVRKDGNEQYVNVAGQFAHYLEDPYSERIERAPVTDHVEVAVIGGGFGGLLSAA
RLRKAGFKDIRMIETGGDFGGTWYWNRYPGAACDIESYIYLPLLEETGYIPKEKYTKAPEILEHSSRIAKHFGLYENALL
GTGVTGMKWDEARKVWIIETDRNDRFTAQFVIMSNGPLNRPKLPGIPGVESFKGHSFHTSRWDYAYTGGDSTGGLTKLKD
KVVGIIGTGATAVQCVPHLAAGAKQLYVFQRTPSSIDVRNDKPTDPDWAKSLEPGWQRRRMENFNTLVSGGYEPEDLVQD
GWTDIIRNILFLASSGDTQGLTPDRLAELAELADYKKMEQVRGRVDEVVKDPDTAAKLKPWYRQFCKRPCFHDAYLNSFN
RPTVTLVDTGGQGVERITEDSIIADGVEYKIDCLVYATGFEVGTDYTRRAGYDPVGKDGVTMKDHWADGMRSLHGLAVNN
FPNMFLMGPGQAGFTANYPHLLDEQAEQIAYILSEVSARQASTFEASPEGEAAWVQKVIEKAMMRQEFLEECTPGYYNNE
GKPSDRAAQNNSYGEGPNAYFRILKAWRESGELNGLELS

Sequences:

>Translated_599_residues
MADNAALDLDFDPNELRDRYRAERDKRVRKDGNEQYVNVAGQFAHYLEDPYSERIERAPVTDHVEVAVIGGGFGGLLSAA
RLRKAGFKDIRMIETGGDFGGTWYWNRYPGAACDIESYIYLPLLEETGYIPKEKYTKAPEILEHSSRIAKHFGLYENALL
GTGVTGMKWDEARKVWIIETDRNDRFTAQFVIMSNGPLNRPKLPGIPGVESFKGHSFHTSRWDYAYTGGDSTGGLTKLKD
KVVGIIGTGATAVQCVPHLAAGAKQLYVFQRTPSSIDVRNDKPTDPDWAKSLEPGWQRRRMENFNTLVSGGYEPEDLVQD
GWTDIIRNILFLASSGDTQGLTPDRLAELAELADYKKMEQVRGRVDEVVKDPDTAAKLKPWYRQFCKRPCFHDAYLNSFN
RPTVTLVDTGGQGVERITEDSIIADGVEYKIDCLVYATGFEVGTDYTRRAGYDPVGKDGVTMKDHWADGMRSLHGLAVNN
FPNMFLMGPGQAGFTANYPHLLDEQAEQIAYILSEVSARQASTFEASPEGEAAWVQKVIEKAMMRQEFLEECTPGYYNNE
GKPSDRAAQNNSYGEGPNAYFRILKAWRESGELNGLELS
>Mature_598_residues
ADNAALDLDFDPNELRDRYRAERDKRVRKDGNEQYVNVAGQFAHYLEDPYSERIERAPVTDHVEVAVIGGGFGGLLSAAR
LRKAGFKDIRMIETGGDFGGTWYWNRYPGAACDIESYIYLPLLEETGYIPKEKYTKAPEILEHSSRIAKHFGLYENALLG
TGVTGMKWDEARKVWIIETDRNDRFTAQFVIMSNGPLNRPKLPGIPGVESFKGHSFHTSRWDYAYTGGDSTGGLTKLKDK
VVGIIGTGATAVQCVPHLAAGAKQLYVFQRTPSSIDVRNDKPTDPDWAKSLEPGWQRRRMENFNTLVSGGYEPEDLVQDG
WTDIIRNILFLASSGDTQGLTPDRLAELAELADYKKMEQVRGRVDEVVKDPDTAAKLKPWYRQFCKRPCFHDAYLNSFNR
PTVTLVDTGGQGVERITEDSIIADGVEYKIDCLVYATGFEVGTDYTRRAGYDPVGKDGVTMKDHWADGMRSLHGLAVNNF
PNMFLMGPGQAGFTANYPHLLDEQAEQIAYILSEVSARQASTFEASPEGEAAWVQKVIEKAMMRQEFLEECTPGYYNNEG
KPSDRAAQNNSYGEGPNAYFRILKAWRESGELNGLELS

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Drosophila melanogaster, GI19921694, Length=226, Percent_Identity=29.646017699115, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 67059; Mature: 66928

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNAALDLDFDPNELRDRYRAERDKRVRKDGNEQYVNVAGQFAHYLEDPYSERIERAPV
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHCCCC
TDHVEVAVIGGGFGGLLSAARLRKAGFKDIRMIETGGDFGGTWYWNRYPGAACDIESYIY
CCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCEEE
LPLLEETGYIPKEKYTKAPEILEHSSRIAKHFGLYENALLGTGVTGMKWDEARKVWIIET
EEEHHCCCCCCHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCHHCCCEEEEEEC
DRNDRFTAQFVIMSNGPLNRPKLPGIPGVESFKGHSFHTSRWDYAYTGGDSTGGLTKLKD
CCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHH
KVVGIIGTGATAVQCVPHLAAGAKQLYVFQRTPSSIDVRNDKPTDPDWAKSLEPGWQRRR
HEEEEEECCHHHHHHHHHHHCCCEEEEEEEECCCCEECCCCCCCCCHHHHHCCCCHHHHH
MENFNTLVSGGYEPEDLVQDGWTDIIRNILFLASSGDTQGLTPDRLAELAELADYKKMEQ
HHHHHHHHCCCCCHHHHHHCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
VRGRVDEVVKDPDTAAKLKPWYRQFCKRPCFHDAYLNSFNRPTVTLVDTGGQGVERITED
HHHHHHHHHCCCCCHHHCCHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHC
SIIADGVEYKIDCLVYATGFEVGTDYTRRAGYDPVGKDGVTMKDHWADGMRSLHGLAVNN
CHHHCCCCEEEEEEEEEECCCCCCCHHHHCCCCCCCCCCCEEHHHHHHHHHHHHCEEECC
FPNMFLMGPGQAGFTANYPHLLDEQAEQIAYILSEVSARQASTFEASPEGEAAWVQKVIE
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
KAMMRQEFLEECTPGYYNNEGKPSDRAAQNNSYGEGPNAYFRILKAWRESGELNGLELS
HHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ADNAALDLDFDPNELRDRYRAERDKRVRKDGNEQYVNVAGQFAHYLEDPYSERIERAPV
CCCCEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHHCCCC
TDHVEVAVIGGGFGGLLSAARLRKAGFKDIRMIETGGDFGGTWYWNRYPGAACDIESYIY
CCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCEEE
LPLLEETGYIPKEKYTKAPEILEHSSRIAKHFGLYENALLGTGVTGMKWDEARKVWIIET
EEEHHCCCCCCHHHHCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCCCHHCCCEEEEEEC
DRNDRFTAQFVIMSNGPLNRPKLPGIPGVESFKGHSFHTSRWDYAYTGGDSTGGLTKLKD
CCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHH
KVVGIIGTGATAVQCVPHLAAGAKQLYVFQRTPSSIDVRNDKPTDPDWAKSLEPGWQRRR
HEEEEEECCHHHHHHHHHHHCCCEEEEEEEECCCCEECCCCCCCCCHHHHHCCCCHHHHH
MENFNTLVSGGYEPEDLVQDGWTDIIRNILFLASSGDTQGLTPDRLAELAELADYKKMEQ
HHHHHHHHCCCCCHHHHHHCCHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHH
VRGRVDEVVKDPDTAAKLKPWYRQFCKRPCFHDAYLNSFNRPTVTLVDTGGQGVERITED
HHHHHHHHHCCCCCHHHCCHHHHHHHCCCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHC
SIIADGVEYKIDCLVYATGFEVGTDYTRRAGYDPVGKDGVTMKDHWADGMRSLHGLAVNN
CHHHCCCCEEEEEEEEEECCCCCCCHHHHCCCCCCCCCCCEEHHHHHHHHHHHHCEEECC
FPNMFLMGPGQAGFTANYPHLLDEQAEQIAYILSEVSARQASTFEASPEGEAAWVQKVIE
CCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
KAMMRQEFLEECTPGYYNNEGKPSDRAAQNNSYGEGPNAYFRILKAWRESGELNGLELS
HHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA