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The map label for this gene is ribD [H]

Identifier: 114798109

GI number: 114798109

Start: 21031

End: 21489

Strand: Reverse

Name: ribD [H]

Synonym: HNE_0030

Alternate gene names: 114798109

Gene position: 21489-21031 (Counterclockwise)

Preceding gene: 114797148

Following gene: 114797893

Centisome position: 0.58

GC content: 68.63

Gene sequence:

>459_bases
ATGAAACGGCCGGGGCGGCGCCGGGACCGCAGGATGATGGGCCGGGCCTTTCAACTGGCGCGTCTCAATCATGGCCTGAC
CGGCAAGAACCCATCGGTGGGATGCCTCATTCTGGATGCGCGCGGACATATTGCCGGCGCCGGCGTGACCGGCACAGGCG
GCGCGCCGCATGCGGAGGAAGTCGCGCTGGACGAGGCGGCGGGAAAAGCGGCCGGCGGCACAGCCTATGTGACACTGGAG
CCCTGTCGCGAACGCTCGTCCGGCGCGCCCTCGTGTGCCCGCAAGCTGGTGGAGGCCGGCATCGCGCGCGTTGTTGTGGC
GATTGAAGATCCCCACCCCACGGCGCGGGATGGCCTGGCCATATTGCGCGAGGCCGGTGTGCGGGTGGAGACAGGGCTCG
GAAAATACACCGCGGCCCGGCTTTACCGCGCGTTCTTCGCCGCAACGAAAGGGTCCTGA

Upstream 100 bases:

>100_bases
CTACCGGAAATCCCTTGCTGATCGAGCTTGATCCCAATCTCAAGCCGGTATCGGTTCGCTATCTCGACGCAGAGCGCGCC
CATAGCCTGCCTGACCTGCC

Downstream 100 bases:

>100_bases
TCAGCCCTCAAAAGGCCCGGCATGGTCGCGGATGCGCTCATAAAGCGCCGCCGAGTCGCGCTGGAAGGCCGCCTTGTTGA
ACTGCGCTTCATAGCTGGCG

Product: riboflavin biosynthesis protein RibD domain-containing protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKRPGRRRDRRMMGRAFQLARLNHGLTGKNPSVGCLILDARGHIAGAGVTGTGGAPHAEEVALDEAAGKAAGGTAYVTLE
PCRERSSGAPSCARKLVEAGIARVVVAIEDPHPTARDGLAILREAGVRVETGLGKYTAARLYRAFFAATKGS

Sequences:

>Translated_152_residues
MKRPGRRRDRRMMGRAFQLARLNHGLTGKNPSVGCLILDARGHIAGAGVTGTGGAPHAEEVALDEAAGKAAGGTAYVTLE
PCRERSSGAPSCARKLVEAGIARVVVAIEDPHPTARDGLAILREAGVRVETGLGKYTAARLYRAFFAATKGS
>Mature_152_residues
MKRPGRRRDRRMMGRAFQLARLNHGLTGKNPSVGCLILDARGHIAGAGVTGTGGAPHAEEVALDEAAGKAAGGTAYVTLE
PCRERSSGAPSCARKLVEAGIARVVVAIEDPHPTARDGLAILREAGVRVETGLGKYTAARLYRAFFAATKGS

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=140, Percent_Identity=43.5714285714286, Blast_Score=99, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 15861; Mature: 15861

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPGRRRDRRMMGRAFQLARLNHGLTGKNPSVGCLILDARGHIAGAGVTGTGGAPHAEE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCHHH
VALDEAAGKAAGGTAYVTLEPCRERSSGAPSCARKLVEAGIARVVVAIEDPHPTARDGLA
HHHHHHCCCCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCHHHHHH
ILREAGVRVETGLGKYTAARLYRAFFAATKGS
HHHHCCCEEECCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRPGRRRDRRMMGRAFQLARLNHGLTGKNPSVGCLILDARGHIAGAGVTGTGGAPHAEE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCHHH
VALDEAAGKAAGGTAYVTLEPCRERSSGAPSCARKLVEAGIARVVVAIEDPHPTARDGLA
HHHHHHCCCCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHEEEEEEECCCCCHHHHHH
ILREAGVRVETGLGKYTAARLYRAFFAATKGS
HHHHCCCEEECCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]