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The map label for this gene is atpC

Identifier: 114798087

GI number: 114798087

Start: 1957560

End: 1957967

Strand: Reverse

Name: atpC

Synonym: HNE_1891

Alternate gene names: 114798087

Gene position: 1957967-1957560 (Counterclockwise)

Preceding gene: 114800518

Following gene: 114798401

Centisome position: 52.85

GC content: 58.58

Gene sequence:

>408_bases
ATGGCTGACAAGCTGCACTTCTCGCTCGTATCGCCCGCCCGAGAGCTGTTCTCGGGGCAGGTTGATCATGTGATCGCTCC
GGGTACGGAAGGTGAGTTTGGCGTTCTTGTAAACCATGCGCCCTTCATGACGACGCTCAAGAATGGCGTTGTCCGTGTGC
TTGAAGGGGATGTCGTCCGGCACCGTTTCTATGTGCGTGGCGGGTTTGCGGACGTGACGCCTGCTGGCCTCACCATCCTG
GCTGAAGAAGCCCGCAATCTGTCTGATGCGAGCGCTCAGGAAATCGACGTTGAGGTCGAAGCTGCAAAGCTGAAGCTTCT
CGAGCTCGACGCGGGTGATACCAAGCGCGCCGTGCTTGAGCACCAGATTTCCTACCTTGAGGGCCTGCGCAGCGCTCTGG
CAAATTGA

Upstream 100 bases:

>100_bases
ACCACCTGCCAGAGCCTGCCTTCTACATGGTCGGCAACATCGAGGAAGCCAAAGCCAAAGCTGCGAAGCTGATGGCGGAC
GCTGCCTGAGGAATTAGTTG

Downstream 100 bases:

>100_bases
TCAGCAAGCGGCAGAACGAAAAAAGCCCCGGCCGTTGAGCCGGGGCTTTTTTGTTGGCGCTGACATCGTGCTCAAATGAA
CAGCGCGATGGTTTGACGGC

Product: ATP synthase F1 subunit epsilon

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MADKLHFSLVSPARELFSGQVDHVIAPGTEGEFGVLVNHAPFMTTLKNGVVRVLEGDVVRHRFYVRGGFADVTPAGLTIL
AEEARNLSDASAQEIDVEVEAAKLKLLELDAGDTKRAVLEHQISYLEGLRSALAN

Sequences:

>Translated_135_residues
MADKLHFSLVSPARELFSGQVDHVIAPGTEGEFGVLVNHAPFMTTLKNGVVRVLEGDVVRHRFYVRGGFADVTPAGLTIL
AEEARNLSDASAQEIDVEVEAAKLKLLELDAGDTKRAVLEHQISYLEGLRSALAN
>Mature_134_residues
ADKLHFSLVSPARELFSGQVDHVIAPGTEGEFGVLVNHAPFMTTLKNGVVRVLEGDVVRHRFYVRGGFADVTPAGLTILA
EEARNLSDASAQEIDVEVEAAKLKLLELDAGDTKRAVLEHQISYLEGLRSALAN

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family

Homologues:

Organism=Escherichia coli, GI1790169, Length=97, Percent_Identity=35.0515463917526, Blast_Score=69, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320200, Length=132, Percent_Identity=37.8787878787879, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATPE_HYPNA (Q0C101)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760592.1
- ProteinModelPortal:   Q0C101
- SMR:   Q0C101
- STRING:   Q0C101
- GeneID:   4288235
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1891
- NMPDR:   fig|228405.5.peg.1820
- TIGR:   HNE_1891
- eggNOG:   COG0355
- HOGENOM:   HBG663981
- OMA:   YKSIQHQ
- PhylomeDB:   Q0C101
- ProtClustDB:   CLSK2531766
- BioCyc:   HNEP81032:HNE_1891-MONOMER
- HAMAP:   MF_00530
- InterPro:   IPR001469
- InterPro:   IPR020546
- Gene3D:   G3DSA:2.60.15.10
- PANTHER:   PTHR13822
- ProDom:   PD000944
- TIGRFAMs:   TIGR01216

Pfam domain/function: PF02823 ATP-synt_DE_N; SSF51344 ATPsynt_DE

EC number: 3.6.3.14

Molecular weight: Translated: 14610; Mature: 14479

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKLHFSLVSPARELFSGQVDHVIAPGTEGEFGVLVNHAPFMTTLKNGVVRVLEGDVVR
CCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCHHHHHHHHHEEECCCHHHH
HRFYVRGGFADVTPAGLTILAEEARNLSDASAQEIDVEVEAAKLKLLELDAGDTKRAVLE
HEEEEECCCCCCCCCCCEEEEHHHCCCCCCCCHHEEEEEEEEEEEEEEECCCCHHHHHHH
HQISYLEGLRSALAN
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADKLHFSLVSPARELFSGQVDHVIAPGTEGEFGVLVNHAPFMTTLKNGVVRVLEGDVVR
CCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCHHHHHHHHHEEECCCHHHH
HRFYVRGGFADVTPAGLTILAEEARNLSDASAQEIDVEVEAAKLKLLELDAGDTKRAVLE
HEEEEECCCCCCCCCCCEEEEHHHCCCCCCCCHHEEEEEEEEEEEEEEECCCCHHHHHHH
HQISYLEGLRSALAN
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA