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The map label for this gene is alr1 [H]

Identifier: 114797948

GI number: 114797948

Start: 738110

End: 739165

Strand: Reverse

Name: alr1 [H]

Synonym: HNE_0725

Alternate gene names: 114797948

Gene position: 739165-738110 (Counterclockwise)

Preceding gene: 114797393

Following gene: 114798102

Centisome position: 19.95

GC content: 62.78

Gene sequence:

>1056_bases
ATGAGCCAGATGCCCCGCGCCACCGTGCTGACCGGTAATATTGCCGACAATTGGAGAACCCTGGACGCCCTTCATCCAGG
CGCGACAACGGCTGCGGTCGTCAAGGCCGACGCCTACGGGCTCGGCGCCATGCGCGTCGCCCGCGCCCTGAGGATAGCAG
GCTGCCAGACCTTCTTCGTTGCCTATGCAGAAGAGGGTCTGATCGTGCGCAAGGCGGCCGGAAAAGCCGCGCGGATCTTC
GTGCTCAACGGCCCGGTGCGCAGTGAAATGGCCACCTATCGCGACGCAGACCTGACAGCTGTTCTTTCCAGTGAAGCGCA
CGTGAAACTGTGGGGGACAGCGCCGAAGGGGTCATGCGCGCTGCACTTTGATACGGGGATGAACCGGCTCGGCCTGCCGA
TGGACATGAGCGAGAAGGATCTCGCCGCGCTGCGCCGGTTGCAGCCAGTGTTGATCATGAGTCACCTGGCCTGTGCGGAC
GATCCGGAAAACCCTGCAAATACAGCGCAGCGGAAGGCCTTCAACGAGATTTCGGACGCCTTCCCCGATACGCCCGCCAG
CCTCGCCAATTCCAACGGATGCTATCTCGGCAAAGGCTTTGCCTATGATCTGACCCGGCCGGGCCTGGCCCTCTATGGCG
GCACGACCCCGCCAGAGAAGGTCAAACTGAAGCCCGGCGTGATCCTCGAAGCGAGCATTCTGGCGACATTTTCGGGACAA
ACCGGGACAAAAGTGGGCTATGGCGGGACACATACGCTCCCCGAAGACCGCATTCTGGCCACCTGCGCGCTCGGGTATGC
CGACGGCATTCCCCGCGCCGGGGCGAACCAGATCACGGGCTGGCTGGAGGGCAATCCTTGCCCGGTCCTCGGGCGGATTT
CGATGGATCTGATCACTCTGGACGTGACCGATTGCGTCAAACACGCAAAGCCGGGCGCGCGGGTTGAATTTTTGGGCGAG
AACGCCAAACTGGAGGTTCAGGCGGCTGCTTGCGGCACGCTGGGTTACGAACTGCTGACCGGCCTTGGCCCCAGAGTGCA
ACGTGTCTACCGCTGA

Upstream 100 bases:

>100_bases
CACCGGTCTGGAATATGAAGGGCTCAGCCTGGCTGGCACACAACGAAGGCGGCAAGCAGGCAGGATGACAACGGGCTGAA
ACTCGCCTAGCGGTGAGCCC

Downstream 100 bases:

>100_bases
GGCCTGATGATGCAGAACCCTATTCAACTCATTGGCCGGGCAACGCTTGGGCTGTTCGGGGAAGTCGGCCGGCTGGCCGT
CTTTGCCGGCCGCGTCAAAG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSQMPRATVLTGNIADNWRTLDALHPGATTAAVVKADAYGLGAMRVARALRIAGCQTFFVAYAEEGLIVRKAAGKAARIF
VLNGPVRSEMATYRDADLTAVLSSEAHVKLWGTAPKGSCALHFDTGMNRLGLPMDMSEKDLAALRRLQPVLIMSHLACAD
DPENPANTAQRKAFNEISDAFPDTPASLANSNGCYLGKGFAYDLTRPGLALYGGTTPPEKVKLKPGVILEASILATFSGQ
TGTKVGYGGTHTLPEDRILATCALGYADGIPRAGANQITGWLEGNPCPVLGRISMDLITLDVTDCVKHAKPGARVEFLGE
NAKLEVQAAACGTLGYELLTGLGPRVQRVYR

Sequences:

>Translated_351_residues
MSQMPRATVLTGNIADNWRTLDALHPGATTAAVVKADAYGLGAMRVARALRIAGCQTFFVAYAEEGLIVRKAAGKAARIF
VLNGPVRSEMATYRDADLTAVLSSEAHVKLWGTAPKGSCALHFDTGMNRLGLPMDMSEKDLAALRRLQPVLIMSHLACAD
DPENPANTAQRKAFNEISDAFPDTPASLANSNGCYLGKGFAYDLTRPGLALYGGTTPPEKVKLKPGVILEASILATFSGQ
TGTKVGYGGTHTLPEDRILATCALGYADGIPRAGANQITGWLEGNPCPVLGRISMDLITLDVTDCVKHAKPGARVEFLGE
NAKLEVQAAACGTLGYELLTGLGPRVQRVYR
>Mature_350_residues
SQMPRATVLTGNIADNWRTLDALHPGATTAAVVKADAYGLGAMRVARALRIAGCQTFFVAYAEEGLIVRKAAGKAARIFV
LNGPVRSEMATYRDADLTAVLSSEAHVKLWGTAPKGSCALHFDTGMNRLGLPMDMSEKDLAALRRLQPVLIMSHLACADD
PENPANTAQRKAFNEISDAFPDTPASLANSNGCYLGKGFAYDLTRPGLALYGGTTPPEKVKLKPGVILEASILATFSGQT
GTKVGYGGTHTLPEDRILATCALGYADGIPRAGANQITGWLEGNPCPVLGRISMDLITLDVTDCVKHAKPGARVEFLGEN
AKLEVQAAACGTLGYELLTGLGPRVQRVYR

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=372, Percent_Identity=33.0645161290323, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1787439, Length=331, Percent_Identity=29.9093655589124, Blast_Score=123, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 37173; Mature: 37042

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQMPRATVLTGNIADNWRTLDALHPGATTAAVVKADAYGLGAMRVARALRIAGCQTFFV
CCCCCCEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCHHEEEE
AYAEEGLIVRKAAGKAARIFVLNGPVRSEMATYRDADLTAVLSSEAHVKLWGTAPKGSCA
EECCCCEEEEECCCCEEEEEEECCCHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCEE
LHFDTGMNRLGLPMDMSEKDLAALRRLQPVLIMSHLACADDPENPANTAQRKAFNEISDA
EEECCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
FPDTPASLANSNGCYLGKGFAYDLTRPGLALYGGTTPPEKVKLKPGVILEASILATFSGQ
CCCCCHHHCCCCCEEEECCEEEECCCCCEEEECCCCCCCCEEECCCEEEEEEEEEEECCC
TGTKVGYGGTHTLPEDRILATCALGYADGIPRAGANQITGWLEGNPCPVLGRISMDLITL
CCCEECCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCEEEEECCCCCCEEEEEEEEEEEE
DVTDCVKHAKPGARVEFLGENAKLEVQAAACGTLGYELLTGLGPRVQRVYR
EHHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCHHHHHHCC
>Mature Secondary Structure 
SQMPRATVLTGNIADNWRTLDALHPGATTAAVVKADAYGLGAMRVARALRIAGCQTFFV
CCCCCEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCHHEEEE
AYAEEGLIVRKAAGKAARIFVLNGPVRSEMATYRDADLTAVLSSEAHVKLWGTAPKGSCA
EECCCCEEEEECCCCEEEEEEECCCHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCEE
LHFDTGMNRLGLPMDMSEKDLAALRRLQPVLIMSHLACADDPENPANTAQRKAFNEISDA
EEECCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
FPDTPASLANSNGCYLGKGFAYDLTRPGLALYGGTTPPEKVKLKPGVILEASILATFSGQ
CCCCCHHHCCCCCEEEECCEEEECCCCCEEEECCCCCCCCEEECCCEEEEEEEEEEECCC
TGTKVGYGGTHTLPEDRILATCALGYADGIPRAGANQITGWLEGNPCPVLGRISMDLITL
CCCEECCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCEEEEECCCCCCEEEEEEEEEEEE
DVTDCVKHAKPGARVEFLGENAKLEVQAAACGTLGYELLTGLGPRVQRVYR
EHHHHHHHCCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA