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The map label for this gene is suhB [H]

Identifier: 114797941

GI number: 114797941

Start: 3361091

End: 3361912

Strand: Direct

Name: suhB [H]

Synonym: HNE_3187

Alternate gene names: 114797941

Gene position: 3361091-3361912 (Clockwise)

Preceding gene: 114797291

Following gene: 114800504

Centisome position: 90.72

GC content: 64.84

Gene sequence:

>822_bases
ATGTCGAAACCATCCCCCGTTGGAGCCGTGATGATTGCCGCTGCCCTCGCTGCTGGCCGCAGCCTGGCGCGCGATTTTGG
CGAAGTGGAAAACCTGCAGGTTTCGCGCAAAGGCCCGGCTGATTTCGTCACCAGCGCCGACATGCGCGCCGAAGAGATCA
TCCATGCCAGCCTCACCAAAGCCCGCCCCGGCTATGGCTTCCTCATGGAAGAGCGCGGCATCGTCGAAGGCACCGACAAA
TCCAACCGTTTCATCGTCGATCCCCTCGATGGCACGCTGAACTTCATGCACGGCCAGCCTCATTACGCCGTCTCCATCGG
CCTGGAGCGCGATGGCAAGCCCTTCGCCGGCGTCGTGTTCGATGTCGCCAAGAACGAGATCTTCTGGGCCGAAGTCGGCC
GCGGCGCCTGGCTCGACCAGCGCAAGCTGCGCGTTGCCGTCCGCAAGAAGCTCGGCGAAGCCGTCGTCGCCACCGGCACG
CCCTGGATGGGCAAGAGCGAAGAAAGCCACATCACCTTTGCCCGCGAGATGGCCGCGATGACGCCGACCTGCGCCGGCAT
CCGCCGTTATGGCTCGGCTGCGCTGGACCTCGCCTGGGTGGCCGCCGGCCGCTTTGACGCCTTCTGGGAACACGGCCTGA
AGCCCTGGGACATCGCTGCGGGCATCGTCCTCGTGCGCGAAGCAGGCGGCATTGTCGAAGAAATCAACGGCGGCGATGTA
ATGAAAACCGGCAGCATCCTGGCCGGCAACGAAGACATCGTACCCCCCGTGATGCACCAGCTGCGCCACGCGGCCTCCTT
CGGCAAGGCCGCGAAGGTCTAG

Upstream 100 bases:

>100_bases
AATCGGCCCTGTCCATTAACACTCTGGCGCCTTGACCCTGAGCGATCAAAGGCTTACGCCCCCCGATCCCGCCATAAATG
CGCCTAGACGAGACGTTCCC

Downstream 100 bases:

>100_bases
CCTTCGCCCTCCCCCGCGCTCCGCGCGCGCCGGACAGCCCCGATTATGACATGGCCCGTGCCCGATTATTTTCGGTGACG
CGTGCGTCACCTATTTTAAT

Product: inositol-1-monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSKPSPVGAVMIAAALAAGRSLARDFGEVENLQVSRKGPADFVTSADMRAEEIIHASLTKARPGYGFLMEERGIVEGTDK
SNRFIVDPLDGTLNFMHGQPHYAVSIGLERDGKPFAGVVFDVAKNEIFWAEVGRGAWLDQRKLRVAVRKKLGEAVVATGT
PWMGKSEESHITFAREMAAMTPTCAGIRRYGSAALDLAWVAAGRFDAFWEHGLKPWDIAAGIVLVREAGGIVEEINGGDV
MKTGSILAGNEDIVPPVMHQLRHAASFGKAAKV

Sequences:

>Translated_273_residues
MSKPSPVGAVMIAAALAAGRSLARDFGEVENLQVSRKGPADFVTSADMRAEEIIHASLTKARPGYGFLMEERGIVEGTDK
SNRFIVDPLDGTLNFMHGQPHYAVSIGLERDGKPFAGVVFDVAKNEIFWAEVGRGAWLDQRKLRVAVRKKLGEAVVATGT
PWMGKSEESHITFAREMAAMTPTCAGIRRYGSAALDLAWVAAGRFDAFWEHGLKPWDIAAGIVLVREAGGIVEEINGGDV
MKTGSILAGNEDIVPPVMHQLRHAASFGKAAKV
>Mature_272_residues
SKPSPVGAVMIAAALAAGRSLARDFGEVENLQVSRKGPADFVTSADMRAEEIIHASLTKARPGYGFLMEERGIVEGTDKS
NRFIVDPLDGTLNFMHGQPHYAVSIGLERDGKPFAGVVFDVAKNEIFWAEVGRGAWLDQRKLRVAVRKKLGEAVVATGTP
WMGKSEESHITFAREMAAMTPTCAGIRRYGSAALDLAWVAAGRFDAFWEHGLKPWDIAAGIVLVREAGGIVEEINGGDVM
KTGSILAGNEDIVPPVMHQLRHAASFGKAAKV

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=244, Percent_Identity=31.5573770491803, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI221625487, Length=244, Percent_Identity=31.5573770491803, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI7657236, Length=256, Percent_Identity=30.46875, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI221625507, Length=144, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788882, Length=262, Percent_Identity=41.9847328244275, Blast_Score=207, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI193202572, Length=247, Percent_Identity=29.9595141700405, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193202570, Length=252, Percent_Identity=28.968253968254, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320493, Length=208, Percent_Identity=36.5384615384615, Blast_Score=134, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6321836, Length=212, Percent_Identity=31.1320754716981, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24664922, Length=231, Percent_Identity=33.7662337662338, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21357329, Length=234, Percent_Identity=34.1880341880342, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24664926, Length=231, Percent_Identity=32.9004329004329, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24664918, Length=266, Percent_Identity=30.8270676691729, Blast_Score=120, Evalue=8e-28,
Organism=Drosophila melanogaster, GI21357957, Length=264, Percent_Identity=31.0606060606061, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357303, Length=227, Percent_Identity=30.8370044052863, Blast_Score=111, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29355; Mature: 29224

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPSPVGAVMIAAALAAGRSLARDFGEVENLQVSRKGPADFVTSADMRAEEIIHASLTK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHCCCHHHHHHHHHHHHC
ARPGYGFLMEERGIVEGTDKSNRFIVDPLDGTLNFMHGQPHYAVSIGLERDGKPFAGVVF
CCCCCCEEEECCCCEECCCCCCCEEEECCCCCEEECCCCCCEEEEEEECCCCCCHHHHEE
DVAKNEIFWAEVGRGAWLDQRKLRVAVRKKLGEAVVATGTPWMGKSEESHITFAREMAAM
EHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHH
TPTCAGIRRYGSAALDLAWVAAGRFDAFWEHGLKPWDIAAGIVLVREAGGIVEEINGGDV
CCHHHHHHHHCCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHEEEEECCCCCEEECCCCCE
MKTGSILAGNEDIVPPVMHQLRHAASFGKAAKV
EECCCEEECCCCCCHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
SKPSPVGAVMIAAALAAGRSLARDFGEVENLQVSRKGPADFVTSADMRAEEIIHASLTK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHCCCHHHHHHHHHHHHC
ARPGYGFLMEERGIVEGTDKSNRFIVDPLDGTLNFMHGQPHYAVSIGLERDGKPFAGVVF
CCCCCCEEEECCCCEECCCCCCCEEEECCCCCEEECCCCCCEEEEEEECCCCCCHHHHEE
DVAKNEIFWAEVGRGAWLDQRKLRVAVRKKLGEAVVATGTPWMGKSEESHITFAREMAAM
EHHCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHH
TPTCAGIRRYGSAALDLAWVAAGRFDAFWEHGLKPWDIAAGIVLVREAGGIVEEINGGDV
CCHHHHHHHHCCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHEEEEECCCCCEEECCCCCE
MKTGSILAGNEDIVPPVMHQLRHAASFGKAAKV
EECCCEEECCCCCCHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]