| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
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The map label for this gene is mrcA [H]
Identifier: 114797913
GI number: 114797913
Start: 1979762
End: 1982368
Strand: Direct
Name: mrcA [H]
Synonym: HNE_1911
Alternate gene names: 114797913
Gene position: 1979762-1982368 (Clockwise)
Preceding gene: 114799202
Following gene: 114798643
Centisome position: 53.43
GC content: 63.79
Gene sequence:
>2607_bases TTGCAGATGACAGACGCCCCACCGACATTCCAACCCTCCCGGAAGCCCGATCCGTATCGGGAACCAGGCAAGTACGACAA TCTGTGGAAATGGCTGCGCCGCCTCGTCGTGCTCGGCCTTGTGCTGGGCGTCATCGGCATCATCGCGGTATGGGTCTACT TCGCCGCGCTTGGCCGAGACGTGCCCTCGATTGCGAAATTGAAACAGTATGAACCCCCGATCACCTCGCGCGTACACGGC GGTGATGGCGCACTGATTGCCGAATTCGCCAGCCAGCACCGGGTGTTCGTGCCCTACGAATCCATTCCGTCCCATGTGAT CGAGGCGTTCGTCGCCGCCGAGGACAAAAACTTCTTCACCCATGACGGGCTCGACTATGTCGGCATCACCCGCGGCGCCG TGAATACGGCCAAGAACAAGGTGACCGGTTCAGGCGGCATGCAGGGCGGCTCCACGATCACCCAGCAGGTTGCCAAGAAC ATGCTGCTGACGCGCGACCAGAATATCGAGCGCAAGGCAAAAGAAGCCATCGTTGCCCAGCGCATGGAAAAAGAGTTCAC CAAGGAGCAGATCCTCGAACTTTATCTCAACGAAATCTATCTGGGCGGCCAGTCCTACGGCGTCGCTTCGGCCGCGTTGA ACTATTTCAACAAATCCCTGCCGGAGCTGGACCTGTCGGAAGCGGCGATCCTTGCCTCGCTGGCCAAGGCGCCGTCTGCC GTAAACCCCTATACCAACCCCGACCGCCTGCTCGCCCGCCGCAACTACGTGCTCGGCCGCATGGTCGAGGATGGCTACAT CACGAAGGAAGAGTCCGCCGAGGCGCAAGATCGCCCGCTAACCACCACCCGCCGCCTGCGCGGGCCCGAATATGCCGCTG CCACCTATTTCGTGCAGGAACTGCGCCGTGAACTGATCGGCACCTATGGCGAGGACACCCTCGAACAGGGCGGCCTCTCC ATCCGCACAACCATCGACACGCGCCTCCAGCTGGCTGCGCAGCAAGCACTCCAGGACGGACTTGTGGCCTATGACCGCCG CCATGGCTGGCGCGGGCCGCTGACGACGCTGCCGATGGATGAAAATTCTGCGGCCGCGCTCAAGGACGTCGAGCTGCCCG GCGGCTTCGGCACCTGGGAGGCCGCGCTCGTGTCCTCCGTTTCGGCCAACAGCGCCGAACTGCTGCTGACCGACGGCACG ACGATCCGCCTGCCAGCCGAAGAAGTGAAATGGGCCGCCACCTACAAACCCGAAGAGGGCGCGGCCGGCCTCCAGAAGGG CCACGTCATCCTCGCCGAGTTCAAGCGTGAACCCTCCAAGGACGGCGCCAAGGCAACACCAGATGCCACCGCCGCAACCG AAGGCGCCGAAGACGAGGCCGCAGAAGGCCCGCTCGAACCGGTCATGGTGCCGGTGGGCAACGCCACCCTGCGCCAGATC CCGGAAGTTGACGGCTCCCTCATCGCGCTGGACCCGCATACCGGCCGTATTCTCGCGATGCAGGGCGGCTACTCATTCTT CAAGTCGAGCTTCAACCGGGTGACCCAGGCCAAGCGCCAGCCCGGCTCCAGCTTCAAGCCGTTTGTCTATGCTGCCGCGC TGGAAAAAGGCTACACGCCCGCCAGCCGCCTGCTGGACGCGCCGTTTGTATCCTTCGACGTGTCGACCCAGAAATACTGG ACCCCGAAAAACTACACGGCCGGCCAGTCTTCCGGCATGGTCACCATGCGCGTCGCGCTGGAGAAATCGCTCAACATGGT CACCGCCAGGGTGGCTCAGGATATTGGCATGGAGGCGGTCTCTGACCTCTCGGAGCGCCTCGGCGTCTATGAAAAACTTC CGCCTTACGCCGCCATGTCGCTGGGCGCCGGCGATACGACGATGCTCGACCTGACGCGAGGCTATGCTGCCTTCGTCAAT GGCGGCCGCCTCGTCACGCCCACCCTGCTCGACCGCGTGCAGGACCGTTATGGCCGCACCCTCTACAAACATGACACACG CGCCTGCGAAGGCTGTGACGCCGACGAATGGAACGGCGGAGAACCGCCCATCCTGCCCGACACCCGCGAACAGGTACTCG ACCCGATCGTCGCCTATCAGGTCACCCACATGCTTGAGGGCGTTGTGGAGCGCGGCACGGCCCGCCGTGCCCTGCGCGTC GGCAAGCCGCTCGCCGGCAAAACCGGCACAACGGACGACTATCGCGACGCAGTCTTTGTCGGCTTCTCGCCAGACATGGT GGTCGGTATCCGCATCGGCTTCGATGACAACCGCTCGCTGGGCGAAGGCGAAGCCGGTGGCTCCGTCGCTGCGCCGATCT TCACCGACTTCATGGAAAAAGCTCTGGAAAAGGAACCGCCCACGCCGTTCCGCATTCCGCCGGGCGTCCGCCTCGTGAAG ATCGATGCCCGGACCGGCGCGCTCGCCACGCCGGGCACATCCATCGTCATTGATGAAGCCTTCCGCCCTGGCACAGAGCC AGGTCTGACCGCCTTCAACAGCACCGAGGACTGCCTCTCGATCTCGGGTTCCTGTGGCCCGTCGAGCGATCCCTCCTCGC CCGTTGAGGAAGATACGGCCGACGCGGATCTCGGCGACGTCTTCTAG
Upstream 100 bases:
>100_bases TTGCCCGCCACCGGCACGCCTTAGTATAGCCGGAATGGCGTGCGACCTCCCACGCTCGTAGAGTAGACTGTGGCCTCTGG CCCGTGATTCGCCGCAAGGT
Downstream 100 bases:
>100_bases CGCGACAAACGCAGCTTTGACCCCATGCGGCGGCCCGGTTATAGGGTCCGCAGATACTTGCTTCTTTCAATCTTAAATTA CAAAAGGTTCATCATGTCCG
Product: penicillin-binding protein 1A
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 868; Mature: 868
Protein sequence:
>868_residues MQMTDAPPTFQPSRKPDPYREPGKYDNLWKWLRRLVVLGLVLGVIGIIAVWVYFAALGRDVPSIAKLKQYEPPITSRVHG GDGALIAEFASQHRVFVPYESIPSHVIEAFVAAEDKNFFTHDGLDYVGITRGAVNTAKNKVTGSGGMQGGSTITQQVAKN MLLTRDQNIERKAKEAIVAQRMEKEFTKEQILELYLNEIYLGGQSYGVASAALNYFNKSLPELDLSEAAILASLAKAPSA VNPYTNPDRLLARRNYVLGRMVEDGYITKEESAEAQDRPLTTTRRLRGPEYAAATYFVQELRRELIGTYGEDTLEQGGLS IRTTIDTRLQLAAQQALQDGLVAYDRRHGWRGPLTTLPMDENSAAALKDVELPGGFGTWEAALVSSVSANSAELLLTDGT TIRLPAEEVKWAATYKPEEGAAGLQKGHVILAEFKREPSKDGAKATPDATAATEGAEDEAAEGPLEPVMVPVGNATLRQI PEVDGSLIALDPHTGRILAMQGGYSFFKSSFNRVTQAKRQPGSSFKPFVYAAALEKGYTPASRLLDAPFVSFDVSTQKYW TPKNYTAGQSSGMVTMRVALEKSLNMVTARVAQDIGMEAVSDLSERLGVYEKLPPYAAMSLGAGDTTMLDLTRGYAAFVN GGRLVTPTLLDRVQDRYGRTLYKHDTRACEGCDADEWNGGEPPILPDTREQVLDPIVAYQVTHMLEGVVERGTARRALRV GKPLAGKTGTTDDYRDAVFVGFSPDMVVGIRIGFDDNRSLGEGEAGGSVAAPIFTDFMEKALEKEPPTPFRIPPGVRLVK IDARTGALATPGTSIVIDEAFRPGTEPGLTAFNSTEDCLSISGSCGPSSDPSSPVEEDTADADLGDVF
Sequences:
>Translated_868_residues MQMTDAPPTFQPSRKPDPYREPGKYDNLWKWLRRLVVLGLVLGVIGIIAVWVYFAALGRDVPSIAKLKQYEPPITSRVHG GDGALIAEFASQHRVFVPYESIPSHVIEAFVAAEDKNFFTHDGLDYVGITRGAVNTAKNKVTGSGGMQGGSTITQQVAKN MLLTRDQNIERKAKEAIVAQRMEKEFTKEQILELYLNEIYLGGQSYGVASAALNYFNKSLPELDLSEAAILASLAKAPSA VNPYTNPDRLLARRNYVLGRMVEDGYITKEESAEAQDRPLTTTRRLRGPEYAAATYFVQELRRELIGTYGEDTLEQGGLS IRTTIDTRLQLAAQQALQDGLVAYDRRHGWRGPLTTLPMDENSAAALKDVELPGGFGTWEAALVSSVSANSAELLLTDGT TIRLPAEEVKWAATYKPEEGAAGLQKGHVILAEFKREPSKDGAKATPDATAATEGAEDEAAEGPLEPVMVPVGNATLRQI PEVDGSLIALDPHTGRILAMQGGYSFFKSSFNRVTQAKRQPGSSFKPFVYAAALEKGYTPASRLLDAPFVSFDVSTQKYW TPKNYTAGQSSGMVTMRVALEKSLNMVTARVAQDIGMEAVSDLSERLGVYEKLPPYAAMSLGAGDTTMLDLTRGYAAFVN GGRLVTPTLLDRVQDRYGRTLYKHDTRACEGCDADEWNGGEPPILPDTREQVLDPIVAYQVTHMLEGVVERGTARRALRV GKPLAGKTGTTDDYRDAVFVGFSPDMVVGIRIGFDDNRSLGEGEAGGSVAAPIFTDFMEKALEKEPPTPFRIPPGVRLVK IDARTGALATPGTSIVIDEAFRPGTEPGLTAFNSTEDCLSISGSCGPSSDPSSPVEEDTADADLGDVF >Mature_868_residues MQMTDAPPTFQPSRKPDPYREPGKYDNLWKWLRRLVVLGLVLGVIGIIAVWVYFAALGRDVPSIAKLKQYEPPITSRVHG GDGALIAEFASQHRVFVPYESIPSHVIEAFVAAEDKNFFTHDGLDYVGITRGAVNTAKNKVTGSGGMQGGSTITQQVAKN MLLTRDQNIERKAKEAIVAQRMEKEFTKEQILELYLNEIYLGGQSYGVASAALNYFNKSLPELDLSEAAILASLAKAPSA VNPYTNPDRLLARRNYVLGRMVEDGYITKEESAEAQDRPLTTTRRLRGPEYAAATYFVQELRRELIGTYGEDTLEQGGLS IRTTIDTRLQLAAQQALQDGLVAYDRRHGWRGPLTTLPMDENSAAALKDVELPGGFGTWEAALVSSVSANSAELLLTDGT TIRLPAEEVKWAATYKPEEGAAGLQKGHVILAEFKREPSKDGAKATPDATAATEGAEDEAAEGPLEPVMVPVGNATLRQI PEVDGSLIALDPHTGRILAMQGGYSFFKSSFNRVTQAKRQPGSSFKPFVYAAALEKGYTPASRLLDAPFVSFDVSTQKYW TPKNYTAGQSSGMVTMRVALEKSLNMVTARVAQDIGMEAVSDLSERLGVYEKLPPYAAMSLGAGDTTMLDLTRGYAAFVN GGRLVTPTLLDRVQDRYGRTLYKHDTRACEGCDADEWNGGEPPILPDTREQVLDPIVAYQVTHMLEGVVERGTARRALRV GKPLAGKTGTTDDYRDAVFVGFSPDMVVGIRIGFDDNRSLGEGEAGGSVAAPIFTDFMEKALEKEPPTPFRIPPGVRLVK IDARTGALATPGTSIVIDEAFRPGTEPGLTAFNSTEDCLSISGSCGPSSDPSSPVEEDTADADLGDVF
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=882, Percent_Identity=32.766439909297, Blast_Score=421, Evalue=1e-119, Organism=Escherichia coli, GI1786343, Length=268, Percent_Identity=33.5820895522388, Blast_Score=144, Evalue=3e-35, Organism=Escherichia coli, GI1788867, Length=291, Percent_Identity=29.8969072164948, Blast_Score=110, Evalue=5e-25, Organism=Escherichia coli, GI1789601, Length=173, Percent_Identity=31.7919075144509, Blast_Score=84, Evalue=3e-17,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 94059; Mature: 94059
Theoretical pI: Translated: 4.86; Mature: 4.86
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.5 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 0.5 %Cys (Mature Protein) 2.1 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MQMTDAPPTFQPSRKPDPYREPGKYDNLWKWLRRLVVLGLVLGVIGIIAVWVYFAALGRD CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC VPSIAKLKQYEPPITSRVHGGDGALIAEFASQHRVFVPYESIPSHVIEAFVAAEDKNFFT CHHHHHHHHCCCCHHCEEECCCCHHHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCCCCC HDGLDYVGITRGAVNTAKNKVTGSGGMQGGSTITQQVAKNMLLTRDQNIERKAKEAIVAQ CCCCCEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH RMEKEFTKEQILELYLNEIYLGGQSYGVASAALNYFNKSLPELDLSEAAILASLAKAPSA HHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC VNPYTNPDRLLARRNYVLGRMVEDGYITKEESAEAQDRPLTTTRRLRGPEYAAATYFVQE CCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHH LRRELIGTYGEDTLEQGGLSIRTTIDTRLQLAAQQALQDGLVAYDRRHGWRGPLTTLPMD HHHHHHCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCC ENSAAALKDVELPGGFGTWEAALVSSVSANSAELLLTDGTTIRLPAEEVKWAATYKPEEG CCCCHHHEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCEEEECHHHCCEEECCCCCCC AAGLQKGHVILAEFKREPSKDGAKATPDATAATEGAEDEAAEGPLEPVMVPVGNATLRQI CCCHHCCCEEEEECCCCCCCCCCCCCCCCHHCCCCCCCHHCCCCCCCEEEECCCHHHHHC PEVDGSLIALDPHTGRILAMQGGYSFFKSSFNRVTQAKRQPGSSFKPFVYAAALEKGYTP CCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCH ASRLLDAPFVSFDVSTQKYWTPKNYTAGQSSGMVTMRVALEKSLNMVTARVAQDIGMEAV HHHHHCCCCEEEECCCCCEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCHHHH SDLSERLGVYEKLPPYAAMSLGAGDTTMLDLTRGYAAFVNGGRLVTPTLLDRVQDRYGRT HHHHHHHCHHHHCCCHHHHCCCCCCCEEEHHHHCHHHHCCCCEEECHHHHHHHHHHHCCH LYKHDTRACEGCDADEWNGGEPPILPDTREQVLDPIVAYQVTHMLEGVVERGTARRALRV HHHCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GKPLAGKTGTTDDYRDAVFVGFSPDMVVGIRIGFDDNRSLGEGEAGGSVAAPIFTDFMEK CCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH ALEKEPPTPFRIPPGVRLVKIDARTGALATPGTSIVIDEAFRPGTEPGLTAFNSTEDCLS HHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHC ISGSCGPSSDPSSPVEEDTADADLGDVF CCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MQMTDAPPTFQPSRKPDPYREPGKYDNLWKWLRRLVVLGLVLGVIGIIAVWVYFAALGRD CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC VPSIAKLKQYEPPITSRVHGGDGALIAEFASQHRVFVPYESIPSHVIEAFVAAEDKNFFT CHHHHHHHHCCCCHHCEEECCCCHHHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCCCCC HDGLDYVGITRGAVNTAKNKVTGSGGMQGGSTITQQVAKNMLLTRDQNIERKAKEAIVAQ CCCCCEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH RMEKEFTKEQILELYLNEIYLGGQSYGVASAALNYFNKSLPELDLSEAAILASLAKAPSA HHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC VNPYTNPDRLLARRNYVLGRMVEDGYITKEESAEAQDRPLTTTRRLRGPEYAAATYFVQE CCCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHH LRRELIGTYGEDTLEQGGLSIRTTIDTRLQLAAQQALQDGLVAYDRRHGWRGPLTTLPMD HHHHHHCCCCCHHHHHCCCEEEEEHHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCCCC ENSAAALKDVELPGGFGTWEAALVSSVSANSAELLLTDGTTIRLPAEEVKWAATYKPEEG CCCCHHHEEECCCCCCCHHHHHHHHHCCCCCCEEEEECCCEEEECHHHCCEEECCCCCCC AAGLQKGHVILAEFKREPSKDGAKATPDATAATEGAEDEAAEGPLEPVMVPVGNATLRQI CCCHHCCCEEEEECCCCCCCCCCCCCCCCHHCCCCCCCHHCCCCCCCEEEECCCHHHHHC PEVDGSLIALDPHTGRILAMQGGYSFFKSSFNRVTQAKRQPGSSFKPFVYAAALEKGYTP CCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCH ASRLLDAPFVSFDVSTQKYWTPKNYTAGQSSGMVTMRVALEKSLNMVTARVAQDIGMEAV HHHHHCCCCEEEECCCCCEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCHHHH SDLSERLGVYEKLPPYAAMSLGAGDTTMLDLTRGYAAFVNGGRLVTPTLLDRVQDRYGRT HHHHHHHCHHHHCCCHHHHCCCCCCCEEEHHHHCHHHHCCCCEEECHHHHHHHHHHHCCH LYKHDTRACEGCDADEWNGGEPPILPDTREQVLDPIVAYQVTHMLEGVVERGTARRALRV HHHCCCHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GKPLAGKTGTTDDYRDAVFVGFSPDMVVGIRIGFDDNRSLGEGEAGGSVAAPIFTDFMEK CCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHH ALEKEPPTPFRIPPGVRLVKIDARTGALATPGTSIVIDEAFRPGTEPGLTAFNSTEDCLS HHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHC ISGSCGPSSDPSSPVEEDTADADLGDVF CCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9823893 [H]