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The map label for this gene is frr

Identifier: 114797846

GI number: 114797846

Start: 1814743

End: 1815297

Strand: Direct

Name: frr

Synonym: HNE_1771

Alternate gene names: 114797846

Gene position: 1814743-1815297 (Clockwise)

Preceding gene: 114798646

Following gene: 114798355

Centisome position: 48.98

GC content: 55.32

Gene sequence:

>555_bases
ATGAGCTACAGCAAGCAGGATATTGAACGAAGAATGGAGGGCGCCCTGGCTTCATTGGCGTCGGAATTTGCTGGCCTGCG
CACTGGGCGCGCTTCGGTGAACCTTCTCGATTCAATTCAGGTCCCGGCCTATGGCGGCGTAACGCCTCTGAGTCAGGTTG
CGTCTGTGACCGTGTCGGATACCCGAATGCTCTCGGTCAATGTTTGGGACAAAACGGTTGTTGGCGCGGCCGACAGGGCA
ATCCGCGATTCCGGTCTTGGTTTGAACCCAGTGATGGATGGCCAAACGCTTCGCATTCCGATCCCTCCGCTCAATGAAGA
GCGCCGGGTTGAGTTGACCAAAATTGCTGGGAAGTATGCCGAAGCTGCGCGGGTGGCTGTCCGCAATGTGCGTCGAGATG
GAATGGACGATCTCAAGAAAGCAGAGAAAGACGGCGAAATCAGTGAAGATCGTCACCGTGCGCTGACTGAAGAAGTTCAG
AAACTGACGGATGCGTTTGTTAAGCGTGTTGACGAAGCCCTGAAGGCCAAAGAAGCCGAGATCATGCAGGTCTGA

Upstream 100 bases:

>100_bases
CAATCGTCGTATTTTCGCTCAAAGAAGAAGGCTCCCTGTTAAATGTCCTTTATGGACGAGGGACTTCGACGACGATCACC
AAAGAGGGAGCAGAGAAGCC

Downstream 100 bases:

>100_bases
TGTCGCGGGCCTCTGCCCCCCTCAATCCTATTCCGGTGGGCCAACAACCCGTCGTCCCAAAGCATGTGGCAATTATCATG
GATGGAAATGGCCGCTGGGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSYSKQDIERRMEGALASLASEFAGLRTGRASVNLLDSIQVPAYGGVTPLSQVASVTVSDTRMLSVNVWDKTVVGAADRA
IRDSGLGLNPVMDGQTLRIPIPPLNEERRVELTKIAGKYAEAARVAVRNVRRDGMDDLKKAEKDGEISEDRHRALTEEVQ
KLTDAFVKRVDEALKAKEAEIMQV

Sequences:

>Translated_184_residues
MSYSKQDIERRMEGALASLASEFAGLRTGRASVNLLDSIQVPAYGGVTPLSQVASVTVSDTRMLSVNVWDKTVVGAADRA
IRDSGLGLNPVMDGQTLRIPIPPLNEERRVELTKIAGKYAEAARVAVRNVRRDGMDDLKKAEKDGEISEDRHRALTEEVQ
KLTDAFVKRVDEALKAKEAEIMQV
>Mature_183_residues
SYSKQDIERRMEGALASLASEFAGLRTGRASVNLLDSIQVPAYGGVTPLSQVASVTVSDTRMLSVNVWDKTVVGAADRAI
RDSGLGLNPVMDGQTLRIPIPPLNEERRVELTKIAGKYAEAARVAVRNVRRDGMDDLKKAEKDGEISEDRHRALTEEVQK
LTDAFVKRVDEALKAKEAEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=178, Percent_Identity=30.3370786516854, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI291042689, Length=148, Percent_Identity=33.1081081081081, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=51.9125683060109, Blast_Score=177, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=25.9887005649718, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_HYPNA (Q0C1B8)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760475.1
- ProteinModelPortal:   Q0C1B8
- SMR:   Q0C1B8
- STRING:   Q0C1B8
- GeneID:   4288790
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1771
- NMPDR:   fig|228405.5.peg.1705
- TIGR:   HNE_1771
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q0C1B8
- ProtClustDB:   CLSK2531731
- BioCyc:   HNEP81032:HNE_1771-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20179; Mature: 20048

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYSKQDIERRMEGALASLASEFAGLRTGRASVNLLDSIQVPAYGGVTPLSQVASVTVSD
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHCEECC
TRMLSVNVWDKTVVGAADRAIRDSGLGLNPVMDGQTLRIPIPPLNEERRVELTKIAGKYA
CEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
EAARVAVRNVRRDGMDDLKKAEKDGEISEDRHRALTEEVQKLTDAFVKRVDEALKAKEAE
HHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMQV
HHCC
>Mature Secondary Structure 
SYSKQDIERRMEGALASLASEFAGLRTGRASVNLLDSIQVPAYGGVTPLSQVASVTVSD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHCEECC
TRMLSVNVWDKTVVGAADRAIRDSGLGLNPVMDGQTLRIPIPPLNEERRVELTKIAGKYA
CEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
EAARVAVRNVRRDGMDDLKKAEKDGEISEDRHRALTEEVQKLTDAFVKRVDEALKAKEAE
HHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMQV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA