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The map label for this gene is yngJ [H]

Identifier: 114797831

GI number: 114797831

Start: 2935604

End: 2936905

Strand: Reverse

Name: yngJ [H]

Synonym: HNE_2772

Alternate gene names: 114797831

Gene position: 2936905-2935604 (Counterclockwise)

Preceding gene: 114800280

Following gene: 114799900

Centisome position: 79.27

GC content: 61.37

Gene sequence:

>1302_bases
ATGGCTGATACCCAACGTACCCCCGACGCCTATGAGGAACTCAACGACCTGCGCATGTCCGAAGGCGCACGCCCGCTTTA
CGAGCATGTGAAGAAGTTCATTGCGGAAACCGTTCAGCCGATGAGCGAAGAGTTCCACCGCCTCGGCGAGAACAACAAGG
ACATCTGGTCCTACGCTCCCGGCCAGCTGGAATGCCTGGAGAAAGCCAAGGACGAAGCCAAGAAGCAGGGCCTCTGGAAC
TTCTTCCTGCCCGACGCCGAAACCGGCGAAGGCCTGTCGAACCTCGACTACGCCTACATTGCCGCTGAACTCGGCAAGAA
CTCGCTGGCTTCAGAGACCATGAACTGCTCGGCGCCTGACACCGGCAACATGGAAGTGCTCGAGCGCGTCGGCACGCCCG
CCCAGAAGGAACAGTGGCTGAAGCCGCTGCTGGAAGGCAAGATCCGCTCCGCCTTCGCCATGACCGAGCCTGGCATGGCC
TCCTCGGACGCAAAGAACGTCTCGATGAGCGCCGTTCTGGAAGGCGATGAGTGGGTGCTCAACGGCGACAAGTATTACAT
CTCCGGCGCCGGCGACCCGCGCTGCAAGATCATGATCGTCATGTGCAAAACCAATAATGGCGACGATGTGAACCGCCAGC
AGAGCCAGATCCTCGTGCCGCTGCCTTATAAAGGCGTCACGATCCTCGGGCCGATGCACGTGTTCGGCGAGCCTGACGCG
CCTCACGGCCATATGCACATCCGCTTTGAGAATGTCCGCGTTCCGAAGGAAAACATGCTGCTCGGCGAAGGCCGTGGCTT
CGAGATTTCGCAGCTGCGCCTCGGCCCTGGCCGTATCCACCACTGCATGCGCTCCATCGGTTCGGCTGAAAAAGCGCTCG
ACCTGATGTGCGTGCGTGGCCTGGCCCGCGAAGCGTTCGGCCGCCCGCTGGCGAAACTCGGCGGCAACACCGAGATCATC
AGCCGCGCGCGGATTGAAATCGAAGCGATGCGCATGATGGTTCTGAAAGCCGCCAAGGCAATGGATGTTCTCGGCAACAA
GGAAGCCCGCGTCTGGATTTCGATGGTGAAAGCCATGGTGCCTGAGCGCGTGTGCCTGATCATCGACCAGGCGATCCAGA
TCCACGGCGCAACCGGCGTTTCGCAATGGACCCCGCTCGCCCGCATGTATGCCAGCCAGCGCACACTGCGCCTGGCAGAC
GGCCCGGACGAAGTCCACCACATGGTCGTCGGCCGCAGCGAACTGCGCAAATATGAAGGCGGGGTGGAAGATCCTGCGCT
GGCCGCCATCTGGCGCAAATAA

Upstream 100 bases:

>100_bases
TCACGAGGGGGCGAAAGAATTTGCACGCGCCCCCCCATCTCAGTTACCCTGAACTCAGGGAAGAAGACGACAAACACCCA
TCCAGAGAGGAAACACAGCC

Downstream 100 bases:

>100_bases
GCCTGGCACTTTGCCACACGATTGAAGAAACCCTCCCTGTACGCACAGGGAGGGTTTTTTCGTGCGCCGGCCTTTGAAAC
CCGCTAAGCCCTGCCGGTCA

Product: acyl-CoA dehydrogenase family protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MADTQRTPDAYEELNDLRMSEGARPLYEHVKKFIAETVQPMSEEFHRLGENNKDIWSYAPGQLECLEKAKDEAKKQGLWN
FFLPDAETGEGLSNLDYAYIAAELGKNSLASETMNCSAPDTGNMEVLERVGTPAQKEQWLKPLLEGKIRSAFAMTEPGMA
SSDAKNVSMSAVLEGDEWVLNGDKYYISGAGDPRCKIMIVMCKTNNGDDVNRQQSQILVPLPYKGVTILGPMHVFGEPDA
PHGHMHIRFENVRVPKENMLLGEGRGFEISQLRLGPGRIHHCMRSIGSAEKALDLMCVRGLAREAFGRPLAKLGGNTEII
SRARIEIEAMRMMVLKAAKAMDVLGNKEARVWISMVKAMVPERVCLIIDQAIQIHGATGVSQWTPLARMYASQRTLRLAD
GPDEVHHMVVGRSELRKYEGGVEDPALAAIWRK

Sequences:

>Translated_433_residues
MADTQRTPDAYEELNDLRMSEGARPLYEHVKKFIAETVQPMSEEFHRLGENNKDIWSYAPGQLECLEKAKDEAKKQGLWN
FFLPDAETGEGLSNLDYAYIAAELGKNSLASETMNCSAPDTGNMEVLERVGTPAQKEQWLKPLLEGKIRSAFAMTEPGMA
SSDAKNVSMSAVLEGDEWVLNGDKYYISGAGDPRCKIMIVMCKTNNGDDVNRQQSQILVPLPYKGVTILGPMHVFGEPDA
PHGHMHIRFENVRVPKENMLLGEGRGFEISQLRLGPGRIHHCMRSIGSAEKALDLMCVRGLAREAFGRPLAKLGGNTEII
SRARIEIEAMRMMVLKAAKAMDVLGNKEARVWISMVKAMVPERVCLIIDQAIQIHGATGVSQWTPLARMYASQRTLRLAD
GPDEVHHMVVGRSELRKYEGGVEDPALAAIWRK
>Mature_432_residues
ADTQRTPDAYEELNDLRMSEGARPLYEHVKKFIAETVQPMSEEFHRLGENNKDIWSYAPGQLECLEKAKDEAKKQGLWNF
FLPDAETGEGLSNLDYAYIAAELGKNSLASETMNCSAPDTGNMEVLERVGTPAQKEQWLKPLLEGKIRSAFAMTEPGMAS
SDAKNVSMSAVLEGDEWVLNGDKYYISGAGDPRCKIMIVMCKTNNGDDVNRQQSQILVPLPYKGVTILGPMHVFGEPDAP
HGHMHIRFENVRVPKENMLLGEGRGFEISQLRLGPGRIHHCMRSIGSAEKALDLMCVRGLAREAFGRPLAKLGGNTEIIS
RARIEIEAMRMMVLKAAKAMDVLGNKEARVWISMVKAMVPERVCLIIDQAIQIHGATGVSQWTPLARMYASQRTLRLADG
PDEVHHMVVGRSELRKYEGGVEDPALAAIWRK

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI211971008, Length=403, Percent_Identity=48.8833746898263, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI48976061, Length=403, Percent_Identity=48.8833746898263, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI38505218, Length=392, Percent_Identity=50.2551020408163, Blast_Score=370, Evalue=1e-102,
Organism=Homo sapiens, GI4557233, Length=343, Percent_Identity=31.4868804664723, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI4557231, Length=408, Percent_Identity=23.5294117647059, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI187960098, Length=408, Percent_Identity=23.5294117647059, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI7656849, Length=358, Percent_Identity=27.9329608938547, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI21361497, Length=358, Percent_Identity=26.2569832402235, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI76496475, Length=397, Percent_Identity=25.9445843828715, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=397, Percent_Identity=25.9445843828715, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI226958412, Length=402, Percent_Identity=25.6218905472637, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501857, Length=420, Percent_Identity=25, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4501859, Length=393, Percent_Identity=24.9363867684478, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI226958414, Length=356, Percent_Identity=25.561797752809, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI87081958, Length=318, Percent_Identity=27.6729559748428, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786223, Length=299, Percent_Identity=22.0735785953177, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562446, Length=404, Percent_Identity=45.7920792079208, Blast_Score=352, Evalue=3e-97,
Organism=Caenorhabditis elegans, GI17534899, Length=403, Percent_Identity=25.3101736972705, Blast_Score=131, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI71985184, Length=347, Percent_Identity=27.3775216138329, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17570075, Length=409, Percent_Identity=23.7163814180929, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=406, Percent_Identity=22.9064039408867, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17533517, Length=348, Percent_Identity=24.1379310344828, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=395, Percent_Identity=23.2911392405063, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=344, Percent_Identity=24.4186046511628, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=301, Percent_Identity=26.2458471760797, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=265, Percent_Identity=27.5471698113208, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17506239, Length=396, Percent_Identity=23.4848484848485, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=349, Percent_Identity=24.0687679083095, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551932, Length=351, Percent_Identity=21.9373219373219, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356377, Length=344, Percent_Identity=30.5232558139535, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI281363737, Length=361, Percent_Identity=27.1468144044321, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24660351, Length=416, Percent_Identity=25.2403846153846, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24646207, Length=344, Percent_Identity=27.0348837209302, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI21355753, Length=416, Percent_Identity=23.0769230769231, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24666513, Length=292, Percent_Identity=26.027397260274, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19920834, Length=331, Percent_Identity=24.1691842900302, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 48134; Mature: 48003

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTQRTPDAYEELNDLRMSEGARPLYEHVKKFIAETVQPMSEEFHRLGENNKDIWSYAP
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GQLECLEKAKDEAKKQGLWNFFLPDAETGEGLSNLDYAYIAAELGKNSLASETMNCSAPD
CHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCCCCC
TGNMEVLERVGTPAQKEQWLKPLLEGKIRSAFAMTEPGMASSDAKNVSMSAVLEGDEWVL
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEE
NGDKYYISGAGDPRCKIMIVMCKTNNGDDVNRQQSQILVPLPYKGVTILGPMHVFGEPDA
CCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCEEEECCCCCEEEEECHHCCCCCCC
PHGHMHIRFENVRVPKENMLLGEGRGFEISQLRLGPGRIHHCMRSIGSAEKALDLMCVRG
CCCEEEEEEECEECCHHHEEEECCCCCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHH
LAREAFGRPLAKLGGNTEIISRARIEIEAMRMMVLKAAKAMDVLGNKEARVWISMVKAMV
HHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PERVCLIIDQAIQIHGATGVSQWTPLARMYASQRTLRLADGPDEVHHMVVGRSELRKYEG
CHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCHHHHHHHCC
GVEDPALAAIWRK
CCCCCHHHHHCCC
>Mature Secondary Structure 
ADTQRTPDAYEELNDLRMSEGARPLYEHVKKFIAETVQPMSEEFHRLGENNKDIWSYAP
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GQLECLEKAKDEAKKQGLWNFFLPDAETGEGLSNLDYAYIAAELGKNSLASETMNCSAPD
CHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHCCCCCCCCC
TGNMEVLERVGTPAQKEQWLKPLLEGKIRSAFAMTEPGMASSDAKNVSMSAVLEGDEWVL
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCEEEE
NGDKYYISGAGDPRCKIMIVMCKTNNGDDVNRQQSQILVPLPYKGVTILGPMHVFGEPDA
CCCEEEEECCCCCCEEEEEEEEECCCCCCCCCCCCCEEEECCCCCEEEEECHHCCCCCCC
PHGHMHIRFENVRVPKENMLLGEGRGFEISQLRLGPGRIHHCMRSIGSAEKALDLMCVRG
CCCEEEEEEECEECCHHHEEEECCCCCEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHH
LAREAFGRPLAKLGGNTEIISRARIEIEAMRMMVLKAAKAMDVLGNKEARVWISMVKAMV
HHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PERVCLIIDQAIQIHGATGVSQWTPLARMYASQRTLRLADGPDEVHHMVVGRSELRKYEG
CHHHHHHHHHHHHEECCCCCHHHHHHHHHHHCCCEEEECCCHHHHHHHHHCHHHHHHHCC
GVEDPALAAIWRK
CCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]