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The map label for this gene is aao [H]

Identifier: 114797607

GI number: 114797607

Start: 2007981

End: 2009114

Strand: Reverse

Name: aao [H]

Synonym: HNE_1940

Alternate gene names: 114797607

Gene position: 2009114-2007981 (Counterclockwise)

Preceding gene: 114797966

Following gene: 114798576

Centisome position: 54.23

GC content: 64.11

Gene sequence:

>1134_bases
ATGCCTGAGCTTGCCCGCCGATCTGTTCTTCTTGGCCTCGGGGCCAGCGCGCTCACCGCCTGTGTCAGCCAGCCTGCTGC
CATGGCGCCGCCACCGGCGGCACGGACCTTTCCGAAGGTGTTGTCCCAGCGCGACCGGATAACGCGGACAGTGGTTGGCC
TTCGTCCCTTCCGCCCGCAGGGGTTTCGCCTGGAAGCCGAGCGGTTCGGGGACAAAACGGTCATTCACAATTACGGCCAT
GGCGGCTGCGGTGTGACCCTTTCATGGGGCACCTGTCAGCGCGCCGCCGTGATGGCCGGAGAGACGGGCCGGCAAGATGT
GGCCATCCTGGGCGGGGGTGTCATGGGGCTGACCAGCGCGCTGATCCTCGCGCGGCGGGGCCATGATGTGACGGTTTATG
CGGATGTGATGCACCCCAACACGACCTCGAACATCGCCGGCGCGCTCTGGCTGCCCTCCAGCCTGTTTGACCGCGATGTG
GCGAGCGAGGAATTCCTGCGCCTCAACTGGCAGGTGACACGCGAGGCGCATCGGGGGTTTCTGCCCTATGTGAACCGGCC
GGGATATGGGGTGAGCTGGGTGCGCCACTCGGAAGTATCTCCGCGCGTACGCGAGCCGCGCTGGGCACTGCCGGGGGGTG
ATGATCTCTATCCGGATCTGGATGTGCGCACGACCGAGACACGCTTCGGCTTTGCGTATGAGGAGCGATACAACACGCTG
ATGATTGATCCGGATTATTATCTCGACATGCTGATGAAGGATGGCCAGCTGGCGGGCGCCAGATTTGTGGCGCGCCGGTT
TGAGAGCCTTGAGGAGGTTCTCGCCCTGCCACAGCCTGTGATCGTCAATTGCACCGGCCTGGGCGCGGCAAAACTGTTCG
GGGATGAAACCCTGATGCCCATCCGGGGGCAGCTGAGCCATCTGCTGCCGCAGCCGGAGGTCGATTATTCCTACACTGCT
TCAGGGCAGGGCGGCGTGCTTTACATGTTTCCCCGCAAAACAGGATTGGTCCTCGGAGGGAGCCATGGGCGGGGTGACGC
GTCGATGGACATAAGCGAGGCGGAACTCACCCGGATGGTGGACGGGCACGCGGCGCTGGCGGAACGGGCGAGCTTCGTGA
CATTTGCAGGCTGA

Upstream 100 bases:

>100_bases
TTCGGGCAGATGCGCAAATTACCCTTGCCAGTCCTGACACCAAGGTTGGCGGGCGGCATCGGGGGCGGCTAGACAGGAGC
TTCATTTGGAGTGCTGACCG

Downstream 100 bases:

>100_bases
TCGTCAGCGCGGCTGGGGAAACATGGCGTTTTCGGGGTGATTTTGCGGCGGGCGAAACCTGAGGTCCCTTGATGCGTTCG
GCAATGGGAAGCCACGCATC

Product: FAD-binding oxidoreductase

Products: NA

Alternate protein names: DAAO; DAMOX; DAO [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MPELARRSVLLGLGASALTACVSQPAAMAPPPAARTFPKVLSQRDRITRTVVGLRPFRPQGFRLEAERFGDKTVIHNYGH
GGCGVTLSWGTCQRAAVMAGETGRQDVAILGGGVMGLTSALILARRGHDVTVYADVMHPNTTSNIAGALWLPSSLFDRDV
ASEEFLRLNWQVTREAHRGFLPYVNRPGYGVSWVRHSEVSPRVREPRWALPGGDDLYPDLDVRTTETRFGFAYEERYNTL
MIDPDYYLDMLMKDGQLAGARFVARRFESLEEVLALPQPVIVNCTGLGAAKLFGDETLMPIRGQLSHLLPQPEVDYSYTA
SGQGGVLYMFPRKTGLVLGGSHGRGDASMDISEAELTRMVDGHAALAERASFVTFAG

Sequences:

>Translated_377_residues
MPELARRSVLLGLGASALTACVSQPAAMAPPPAARTFPKVLSQRDRITRTVVGLRPFRPQGFRLEAERFGDKTVIHNYGH
GGCGVTLSWGTCQRAAVMAGETGRQDVAILGGGVMGLTSALILARRGHDVTVYADVMHPNTTSNIAGALWLPSSLFDRDV
ASEEFLRLNWQVTREAHRGFLPYVNRPGYGVSWVRHSEVSPRVREPRWALPGGDDLYPDLDVRTTETRFGFAYEERYNTL
MIDPDYYLDMLMKDGQLAGARFVARRFESLEEVLALPQPVIVNCTGLGAAKLFGDETLMPIRGQLSHLLPQPEVDYSYTA
SGQGGVLYMFPRKTGLVLGGSHGRGDASMDISEAELTRMVDGHAALAERASFVTFAG
>Mature_376_residues
PELARRSVLLGLGASALTACVSQPAAMAPPPAARTFPKVLSQRDRITRTVVGLRPFRPQGFRLEAERFGDKTVIHNYGHG
GCGVTLSWGTCQRAAVMAGETGRQDVAILGGGVMGLTSALILARRGHDVTVYADVMHPNTTSNIAGALWLPSSLFDRDVA
SEEFLRLNWQVTREAHRGFLPYVNRPGYGVSWVRHSEVSPRVREPRWALPGGDDLYPDLDVRTTETRFGFAYEERYNTLM
IDPDYYLDMLMKDGQLAGARFVARRFESLEEVLALPQPVIVNCTGLGAAKLFGDETLMPIRGQLSHLLPQPEVDYSYTAS
GQGGVLYMFPRKTGLVLGGSHGRGDASMDISEAELTRMVDGHAALAERASFVTFAG

Specific function: Unknown

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DAMOX/DASOX family [H]

Homologues:

Organism=Homo sapiens, GI40217815, Length=266, Percent_Identity=26.6917293233083, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI148539837, Length=264, Percent_Identity=27.6515151515151, Blast_Score=79, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023209
- InterPro:   IPR006076
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.3.3 [H]

Molecular weight: Translated: 41199; Mature: 41067

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELARRSVLLGLGASALTACVSQPAAMAPPPAARTFPKVLSQRDRITRTVVGLRPFRPQ
CCCHHHHHEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GFRLEAERFGDKTVIHNYGHGGCGVTLSWGTCQRAAVMAGETGRQDVAILGGGVMGLTSA
CCEEEHHHCCCEEEEECCCCCCCEEEEECCCCCHHEEECCCCCCCCEEEECCCHHHHHHH
LILARRGHDVTVYADVMHPNTTSNIAGALWLPSSLFDRDVASEEFLRLNWQVTREAHRGF
HHHHCCCCCEEEEEEEECCCCCCCCCEEEECCHHHHHHCCCCCHHEEEEHEEEHHHHCCC
LPYVNRPGYGVSWVRHSEVSPRVREPRWALPGGDDLYPDLDVRTTETRFGFAYEERYNTL
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEHHCCCEE
MIDPDYYLDMLMKDGQLAGARFVARRFESLEEVLALPQPVIVNCTGLGAAKLFGDETLMP
EECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCC
IRGQLSHLLPQPEVDYSYTASGQGGVLYMFPRKTGLVLGGSHGRGDASMDISEAELTRMV
HHHHHHHHCCCCCCCCEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHH
DGHAALAERASFVTFAG
CCHHHHHHHCCEEEECC
>Mature Secondary Structure 
PELARRSVLLGLGASALTACVSQPAAMAPPPAARTFPKVLSQRDRITRTVVGLRPFRPQ
CCHHHHHEEEECCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
GFRLEAERFGDKTVIHNYGHGGCGVTLSWGTCQRAAVMAGETGRQDVAILGGGVMGLTSA
CCEEEHHHCCCEEEEECCCCCCCEEEEECCCCCHHEEECCCCCCCCEEEECCCHHHHHHH
LILARRGHDVTVYADVMHPNTTSNIAGALWLPSSLFDRDVASEEFLRLNWQVTREAHRGF
HHHHCCCCCEEEEEEEECCCCCCCCCEEEECCHHHHHHCCCCCHHEEEEHEEEHHHHCCC
LPYVNRPGYGVSWVRHSEVSPRVREPRWALPGGDDLYPDLDVRTTETRFGFAYEERYNTL
CCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCEEEHHCCCEE
MIDPDYYLDMLMKDGQLAGARFVARRFESLEEVLALPQPVIVNCTGLGAAKLFGDETLMP
EECCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCC
IRGQLSHLLPQPEVDYSYTASGQGGVLYMFPRKTGLVLGGSHGRGDASMDISEAELTRMV
HHHHHHHHCCCCCCCCEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHH
DGHAALAERASFVTFAG
CCHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]