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The map label for this gene is cspA [H]

Identifier: 114797581

GI number: 114797581

Start: 974869

End: 975078

Strand: Direct

Name: cspA [H]

Synonym: HNE_0960

Alternate gene names: 114797581

Gene position: 974869-975078 (Clockwise)

Preceding gene: 114799237

Following gene: 114799642

Centisome position: 26.31

GC content: 54.29

Gene sequence:

>210_bases
ATGACAAATGGTATCGTGAAGTTCTTCAACAGCCAGAAGGGCTTCGGCTTCATTTCGCCCACCAATGGCGGCAATGACGT
GTTCGTCCATATCTCGACGCTTGAGCGTTCGGGTATCGCCCACCTGAACGAAGGCCAAAAGGTTTCGTTCGACACTGCTA
TCGACAAGCGTTCGGGCAAGTCGGCAGTCAGCGCGATCGAACTGGCCTGA

Upstream 100 bases:

>100_bases
GCGCTCACCAAAGTGAGTTGCGGTTTCAGAAACTCTCCAAAATTCGATATGCAAGGGCTGACACATTGTCCGCCCACCAA
TGACTATGAGACTTATATAA

Downstream 100 bases:

>100_bases
TCTCTCCTGCGGGCTGGTGCCTGAGGCACGCCCGCACAGATGACCAGAATTTTAGGCGCGCCTTCCTGACGGGGGGCGCG
CTTTTCAATTCCGGGGATCA

Product: cold shock protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 69; Mature: 68

Protein sequence:

>69_residues
MTNGIVKFFNSQKGFGFISPTNGGNDVFVHISTLERSGIAHLNEGQKVSFDTAIDKRSGKSAVSAIELA

Sequences:

>Translated_69_residues
MTNGIVKFFNSQKGFGFISPTNGGNDVFVHISTLERSGIAHLNEGQKVSFDTAIDKRSGKSAVSAIELA
>Mature_68_residues
TNGIVKFFNSQKGFGFISPTNGGNDVFVHISTLERSGIAHLNEGQKVSFDTAIDKRSGKSAVSAIELA

Specific function: Binds To And Stimulates The Transcription Of The CCAAT- Containing, Cold-Shock-Inducible Promoters Of The H-Ns And Gyra Proteins. Binds Also To The Inverted Repeat 5'-ATTGG-3'. [C]

COG id: COG1278

COG function: function code K; Cold shock proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CSD (cold-shock) domain [H]

Homologues:

Organism=Escherichia coli, GI1789979, Length=47, Percent_Identity=61.7021276595745, Blast_Score=66, Evalue=5e-13,
Organism=Escherichia coli, GI1787107, Length=52, Percent_Identity=51.9230769230769, Blast_Score=61, Evalue=1e-11,
Organism=Escherichia coli, GI2367114, Length=65, Percent_Identity=44.6153846153846, Blast_Score=60, Evalue=2e-11,
Organism=Escherichia coli, GI1787839, Length=47, Percent_Identity=57.4468085106383, Blast_Score=60, Evalue=2e-11,
Organism=Escherichia coli, GI1786841, Length=65, Percent_Identity=47.6923076923077, Blast_Score=60, Evalue=2e-11,
Organism=Escherichia coli, GI1788126, Length=61, Percent_Identity=49.1803278688525, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019844
- InterPro:   IPR012156
- InterPro:   IPR011129
- InterPro:   IPR002059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00313 CSD [H]

EC number: NA

Molecular weight: Translated: 7343; Mature: 7212

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00352 COLD_SHOCK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNGIVKFFNSQKGFGFISPTNGGNDVFVHISTLERSGIAHLNEGQKVSFDTAIDKRSGK
CCCCEEEEECCCCCCEEECCCCCCCEEEEEEEECCCCCCEECCCCCEEEECCCCCCCCCC
SAVSAIELA
CCEEEEECC
>Mature Secondary Structure 
TNGIVKFFNSQKGFGFISPTNGGNDVFVHISTLERSGIAHLNEGQKVSFDTAIDKRSGK
CCCEEEEECCCCCCEEECCCCCCCEEEEEEEECCCCCCEECCCCCEEEECCCCCCCCCC
SAVSAIELA
CCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10618253; 11481430 [H]