Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 114797564

GI number: 114797564

Start: 1323099

End: 1323839

Strand: Direct

Name: crp [C]

Synonym: HNE_1290

Alternate gene names: 114797564

Gene position: 1323099-1323839 (Clockwise)

Preceding gene: 114800506

Following gene: 114800303

Centisome position: 35.71

GC content: 65.32

Gene sequence:

>741_bases
ATGAACACACAGGATTCGATCGATCTGCAGCGGGGGCGGTGGTTTCCGGCATTGCCGGAGGCGTTGCAGGACGAGGTGAT
GCGCAGCGCGACGCGGCACAGGATGCGGCGGGGCCGGCACATATTCCGGCAGGGCGACCCGGCCAACGGCATCTTCGGGA
TTACCAGCGGAGAGGCCCATATCATCGGGACGACCCTGGCGGGGCTCGACATTCTGGTGGCGGTTTTCCGGCCGGGAGAC
TGGACGGGGTTTCTCTCCAGCGTTGATGAGGGGCCTTACACTTTTTCCGTGGTGGCCAGCCAATCCTGCGAGATTGTGCA
CCTGCCTTTGCCGGCGGTGAAGCGGATTTTCATGTCCGATGTGGAGGGATTCCGCCGGTTCATTCTGCCCGAGCTGGCCT
CGACCCGCGCGATCTATTCGCGGGTGGTGGAGAGCCTGGCCTTTACGCCGTTGCAGCGCCTGGCCCAGCGGCTGGTGGAC
CTGACGAGTGAGCCGCATGGCGACCTGGTGACCTCCTCCTTCATCAGCCCGGTGACGCAGGACCAGATTGCCCTGTCGAT
CATGGCATCGCGCCAGTGGACCAACCGCCTGTTGCAGCATCTGGAACAGGCCGATGTGATCCGCATTTCGCGCGGGCGGA
TCGACATTCGCGACCGCGCGCGGCTGACCCAGCTGGCGGTACATGGTGAGAGCGGCTTTACGCTGGCCGAGACGGCCCCG
GCGCGCGCGGCGGCAGGCTGA

Upstream 100 bases:

>100_bases
AGTACTCCCCTGCAGGATTGCCGATTGTCGTTCCCTTGACAGAAGAAGCTGCTAATCTGGGTGGCAGACGGGGACGGCGG
ATACTGGGGAGGTATCGCCA

Downstream 100 bases:

>100_bases
CCCCGCCGCGCGGCCCGGCCGAAAAACCTAGACGGCGTCGGGGATGTCGGTGATTTCCACGAGGGTTTCGCCACCGCAGG
TGATGGTGATGCTGCGATAG

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: Crp/FNR Family Transcriptional Regulator; Regulatory Protein; Transcription Regulator Protein; Transcriptional Regulator Crp/Fnr Family

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MNTQDSIDLQRGRWFPALPEALQDEVMRSATRHRMRRGRHIFRQGDPANGIFGITSGEAHIIGTTLAGLDILVAVFRPGD
WTGFLSSVDEGPYTFSVVASQSCEIVHLPLPAVKRIFMSDVEGFRRFILPELASTRAIYSRVVESLAFTPLQRLAQRLVD
LTSEPHGDLVTSSFISPVTQDQIALSIMASRQWTNRLLQHLEQADVIRISRGRIDIRDRARLTQLAVHGESGFTLAETAP
ARAAAG

Sequences:

>Translated_246_residues
MNTQDSIDLQRGRWFPALPEALQDEVMRSATRHRMRRGRHIFRQGDPANGIFGITSGEAHIIGTTLAGLDILVAVFRPGD
WTGFLSSVDEGPYTFSVVASQSCEIVHLPLPAVKRIFMSDVEGFRRFILPELASTRAIYSRVVESLAFTPLQRLAQRLVD
LTSEPHGDLVTSSFISPVTQDQIALSIMASRQWTNRLLQHLEQADVIRISRGRIDIRDRARLTQLAVHGESGFTLAETAP
ARAAAG
>Mature_246_residues
MNTQDSIDLQRGRWFPALPEALQDEVMRSATRHRMRRGRHIFRQGDPANGIFGITSGEAHIIGTTLAGLDILVAVFRPGD
WTGFLSSVDEGPYTFSVVASQSCEIVHLPLPAVKRIFMSDVEGFRRFILPELASTRAIYSRVVESLAFTPLQRLAQRLVD
LTSEPHGDLVTSSFISPVTQDQIALSIMASRQWTNRLLQHLEQADVIRISRGRIDIRDRARLTQLAVHGESGFTLAETAP
ARAAAG

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27286; Mature: 27286

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQDSIDLQRGRWFPALPEALQDEVMRSATRHRMRRGRHIFRQGDPANGIFGITSGEAH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCE
IIGTTLAGLDILVAVFRPGDWTGFLSSVDEGPYTFSVVASQSCEIVHLPLPAVKRIFMSD
EEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEECCCCCEEECCHHHHHHHHHHH
VEGFRRFILPELASTRAIYSRVVESLAFTPLQRLAQRLVDLTSEPHGDLVTSSFISPVTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHH
DQIALSIMASRQWTNRLLQHLEQADVIRISRGRIDIRDRARLTQLAVHGESGFTLAETAP
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHEEECCCCCEECCCCC
ARAAAG
CCCCCC
>Mature Secondary Structure
MNTQDSIDLQRGRWFPALPEALQDEVMRSATRHRMRRGRHIFRQGDPANGIFGITSGEAH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCE
IIGTTLAGLDILVAVFRPGDWTGFLSSVDEGPYTFSVVASQSCEIVHLPLPAVKRIFMSD
EEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEEECCCCCEEECCHHHHHHHHHHH
VEGFRRFILPELASTRAIYSRVVESLAFTPLQRLAQRLVDLTSEPHGDLVTSSFISPVTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHH
DQIALSIMASRQWTNRLLQHLEQADVIRISRGRIDIRDRARLTQLAVHGESGFTLAETAP
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHEEECCCCCEECCCCC
ARAAAG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA