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The map label for this gene is tauD [H]

Identifier: 114797498

GI number: 114797498

Start: 922391

End: 923230

Strand: Direct

Name: tauD [H]

Synonym: HNE_0905

Alternate gene names: 114797498

Gene position: 922391-923230 (Clockwise)

Preceding gene: 114800490

Following gene: 114799454

Centisome position: 24.9

GC content: 60.48

Gene sequence:

>840_bases
ATGCAGATCACACCCCTCACAGGCGCCGGCGCTGAAATCACCGGTGTCGACATCCGCGCGCTCACCGCGCCGCAGTTTGA
CGCCGTCCGCCAGGCCTATGCCGATCACGGCGTCATCTTCTTTCGTGATCAGTCGCTCAGCGAAGAGGATCACATCGCCT
TCGCCCGGCGCTTTGGCCCCATCAACATCAACCGCTTCTTTCTCGCGCATGAGCGCTATCCGGAAATCGCGCTGGTGCTG
AAGGAAAAGGAACAGAAAACCAATATCGGCGGTGGGTGGCATACGGATCATTCCTATGACGCCGAGCCCGCAATGGGCTC
TGTCCTCGTCGCGCGCCAGCTGCCCGATGAAGGCGGCGACACCTGGTTTGCCTCCATGTATACCGCTTATGACACGCTCG
ACGCCGACACCCGCAATGAGATTGACAGCCTGCGCGCGGTCCATTCGGCCAAACACATCTTCGGCTCACAGACGGATAAT
TTCTATAAGGCCAACGAAGACACCGGCGGTCGCATCGGTAACACCGCCGCCGCGGACGTTCTGGAAGATGTGGCCCATCC
CGTCGTCATCACCCACCCGCTCAGCGGCAAGAAGGCGCTCTATGTGAACCCCGCCTTCACCACGCGCATCGCGGGCTATT
CGGATGAAGCCTCAAGCGCGTTGCTTATGCGCCTCTACGCCCACGCCATGAATCCAGATCATGCTCACCGCTTCAAATGG
CAGCCGGGCTCGGTTGCCTTCTGGGACAACCGCGCCACCTGGCACTGGGCTATGAATGATTATCACGGGGAGCGCCGCCT
GATGCACCGCATCACGATCGAAGGCTGCGCGCTGAATTAG

Upstream 100 bases:

>100_bases
AAAGGCGCGGCAGTTTAGGCAGACCAATTGCCAATACCCGCCCGCCGGGTTTAAGCTCTCCTCAGCAGCCCGCCACAGGA
GAGCGGGCAGGGAGGAAGCC

Downstream 100 bases:

>100_bases
GAAGCGGGCGGAATAGGCCGCCCCGCCATCAGTCCATCCGGAACTCGACACCTACATCGCGCCCGCTTTCCCACCGCTTC
ATACATGTGCGCGGATATTT

Product: TauD/TfdA family dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MQITPLTGAGAEITGVDIRALTAPQFDAVRQAYADHGVIFFRDQSLSEEDHIAFARRFGPININRFFLAHERYPEIALVL
KEKEQKTNIGGGWHTDHSYDAEPAMGSVLVARQLPDEGGDTWFASMYTAYDTLDADTRNEIDSLRAVHSAKHIFGSQTDN
FYKANEDTGGRIGNTAAADVLEDVAHPVVITHPLSGKKALYVNPAFTTRIAGYSDEASSALLMRLYAHAMNPDHAHRFKW
QPGSVAFWDNRATWHWAMNDYHGERRLMHRITIEGCALN

Sequences:

>Translated_279_residues
MQITPLTGAGAEITGVDIRALTAPQFDAVRQAYADHGVIFFRDQSLSEEDHIAFARRFGPININRFFLAHERYPEIALVL
KEKEQKTNIGGGWHTDHSYDAEPAMGSVLVARQLPDEGGDTWFASMYTAYDTLDADTRNEIDSLRAVHSAKHIFGSQTDN
FYKANEDTGGRIGNTAAADVLEDVAHPVVITHPLSGKKALYVNPAFTTRIAGYSDEASSALLMRLYAHAMNPDHAHRFKW
QPGSVAFWDNRATWHWAMNDYHGERRLMHRITIEGCALN
>Mature_279_residues
MQITPLTGAGAEITGVDIRALTAPQFDAVRQAYADHGVIFFRDQSLSEEDHIAFARRFGPININRFFLAHERYPEIALVL
KEKEQKTNIGGGWHTDHSYDAEPAMGSVLVARQLPDEGGDTWFASMYTAYDTLDADTRNEIDSLRAVHSAKHIFGSQTDN
FYKANEDTGGRIGNTAAADVLEDVAHPVVITHPLSGKKALYVNPAFTTRIAGYSDEASSALLMRLYAHAMNPDHAHRFKW
QPGSVAFWDNRATWHWAMNDYHGERRLMHRITIEGCALN

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=277, Percent_Identity=39.3501805054152, Blast_Score=188, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6322971, Length=272, Percent_Identity=30.8823529411765, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 31200; Mature: 31200

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQITPLTGAGAEITGVDIRALTAPQFDAVRQAYADHGVIFFRDQSLSEEDHIAFARRFGP
CEECCCCCCCCEEECEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCC
ININRFFLAHERYPEIALVLKEKEQKTNIGGGWHTDHSYDAEPAMGSVLVARQLPDEGGD
CCEEEEEEEECCCCCEEEEEECCHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
TWFASMYTAYDTLDADTRNEIDSLRAVHSAKHIFGSQTDNFYKANEDTGGRIGNTAAADV
EEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHH
LEDVAHPVVITHPLSGKKALYVNPAFTTRIAGYSDEASSALLMRLYAHAMNPDHAHRFKW
HHHHCCCEEEEECCCCCEEEEECCHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEC
QPGSVAFWDNRATWHWAMNDYHGERRLMHRITIEGCALN
CCCCEEEECCCCEEEEECCCCCHHHHEEHHEEEEEEECC
>Mature Secondary Structure
MQITPLTGAGAEITGVDIRALTAPQFDAVRQAYADHGVIFFRDQSLSEEDHIAFARRFGP
CEECCCCCCCCEEECEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHCCC
ININRFFLAHERYPEIALVLKEKEQKTNIGGGWHTDHSYDAEPAMGSVLVARQLPDEGGD
CCEEEEEEEECCCCCEEEEEECCHHCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCC
TWFASMYTAYDTLDADTRNEIDSLRAVHSAKHIFGSQTDNFYKANEDTGGRIGNTAAADV
EEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCHHHHHH
LEDVAHPVVITHPLSGKKALYVNPAFTTRIAGYSDEASSALLMRLYAHAMNPDHAHRFKW
HHHHCCCEEEEECCCCCEEEEECCHHHEEECCCCCCHHHHHHHHHHHHHCCCCCCCEEEC
QPGSVAFWDNRATWHWAMNDYHGERRLMHRITIEGCALN
CCCCEEEECCCCEEEEECCCCCHHHHEEHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]