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The map label for this gene is mmgC [H]

Identifier: 114797288

GI number: 114797288

Start: 2849597

End: 2850769

Strand: Reverse

Name: mmgC [H]

Synonym: HNE_2690

Alternate gene names: 114797288

Gene position: 2850769-2849597 (Counterclockwise)

Preceding gene: 114799582

Following gene: 114800172

Centisome position: 76.94

GC content: 61.3

Gene sequence:

>1173_bases
ATGCATGTTATCCAGCCGATGACCGAAGATCAGGCCGCCATCCGCGACGCGGTGGCCAAGACGCTGGAGCCGTTTGACGA
CGCTTACTGGGCCAAGACCGACGAGACGGGCAACTGGCCGGAAGAATTCTGCAACGCGATGGCCAAGGGCGGCTGGCTCG
GCATTGCGTTTCCCGAAGAGTATGGCGGGGCAGGCCTTGGCCTGACCGAAGCGGCGCTGATGATGCAGACCGTGACGCGC
ACGGGCGCGGGCTATTCGGGCGCCTCGGCGATCCACCTCAACATCTTCGGGCCGAAGCCGCTGGAGAAATTCGGCAATCC
GGAACTCAAGCGCGAGAGCCTGCCCAAGATCATCTCCGGCGAAGAGAAGATGTGCTTTGCCGTGACCGAGCCCAACTCCG
GCCTCGACACCTCCAGCCTCGAGACGAAGGCAGAGCGGACCAATACCGGCTATATGATCCATGGGCGGAAGATCTGGACG
ACGGGTGCTCAGCGTGCGGACAAGATCTTGATCATTGCGCGGACGACGCCGAAGGACCAGTGCGCGAAGCCTTATATGGG
GCTGTCGCTGTTCTACACCGATCTCAACCGCAACAAGATCGAAGCCAATGTGATCCCGAAAATGGGCCGCAAGGCGGTGG
AGTGTAACACGCTGTTCATTGACGGGCTGGAAGTGCCCAAGGAACACCTGATCGGCAATGAGGGCGACGGGTTCAAATAT
CTGCTGCAGGGGCTGAACCCTGAGCGGGTTCTGTTTGCTGTTGAGTCTGTCGGCCTTGGATTTGCGGCGCTGGAGCGGGC
GACGCGCTATGCCAATGAGCGGGTGGTGTTTGGCCGGCCGATTGGCCAGAACCAGGGCATTGCCCACCCCCTCGCCAAGT
CGTGGGCGGAGCTTTCAGCCGCTGAGCTGCTCGCCTACAAGGCCGCCTCGCTTTATGATGCCGGGCAGGATTGCGGGGCG
GAAGCCAACGCCGCGAAATATCTGGGGACTGAGGCTGGCTTTACCGCATGCGAGACGGCCGTGCTGACCCATGGCGGCAT
GGGCTATGCCAAGGAATATCATGTTGAGCGGATGATGCGTGAAGCGATGCTGGCGCGGATTGCGCCGGTCAGCCGCGAGA
TGATCCTGAACTTTATCTCCGAGCGCGTGCTGGGGCTGCCCAAGAGTTATTGA

Upstream 100 bases:

>100_bases
CCGCTGCGTTCACCACGCGCCGGGCCTATTCCGCGACGGCCTGACGCTGGACGTGCCCCCTCTCGCGCCTTAAGTCTCGG
CGCCAAAGGGAGCTTACGCC

Downstream 100 bases:

>100_bases
TCTGGAGGCGGACTACATTCCGTCCGCGCCCTTCATCAGCTCGAAGAATTCTTCCTTGCTGTTGGTGCGCGGATAGGGTG
TGGCCGGGACCGGCACGCCG

Product: acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MHVIQPMTEDQAAIRDAVAKTLEPFDDAYWAKTDETGNWPEEFCNAMAKGGWLGIAFPEEYGGAGLGLTEAALMMQTVTR
TGAGYSGASAIHLNIFGPKPLEKFGNPELKRESLPKIISGEEKMCFAVTEPNSGLDTSSLETKAERTNTGYMIHGRKIWT
TGAQRADKILIIARTTPKDQCAKPYMGLSLFYTDLNRNKIEANVIPKMGRKAVECNTLFIDGLEVPKEHLIGNEGDGFKY
LLQGLNPERVLFAVESVGLGFAALERATRYANERVVFGRPIGQNQGIAHPLAKSWAELSAAELLAYKAASLYDAGQDCGA
EANAAKYLGTEAGFTACETAVLTHGGMGYAKEYHVERMMREAMLARIAPVSREMILNFISERVLGLPKSY

Sequences:

>Translated_390_residues
MHVIQPMTEDQAAIRDAVAKTLEPFDDAYWAKTDETGNWPEEFCNAMAKGGWLGIAFPEEYGGAGLGLTEAALMMQTVTR
TGAGYSGASAIHLNIFGPKPLEKFGNPELKRESLPKIISGEEKMCFAVTEPNSGLDTSSLETKAERTNTGYMIHGRKIWT
TGAQRADKILIIARTTPKDQCAKPYMGLSLFYTDLNRNKIEANVIPKMGRKAVECNTLFIDGLEVPKEHLIGNEGDGFKY
LLQGLNPERVLFAVESVGLGFAALERATRYANERVVFGRPIGQNQGIAHPLAKSWAELSAAELLAYKAASLYDAGQDCGA
EANAAKYLGTEAGFTACETAVLTHGGMGYAKEYHVERMMREAMLARIAPVSREMILNFISERVLGLPKSY
>Mature_390_residues
MHVIQPMTEDQAAIRDAVAKTLEPFDDAYWAKTDETGNWPEEFCNAMAKGGWLGIAFPEEYGGAGLGLTEAALMMQTVTR
TGAGYSGASAIHLNIFGPKPLEKFGNPELKRESLPKIISGEEKMCFAVTEPNSGLDTSSLETKAERTNTGYMIHGRKIWT
TGAQRADKILIIARTTPKDQCAKPYMGLSLFYTDLNRNKIEANVIPKMGRKAVECNTLFIDGLEVPKEHLIGNEGDGFKY
LLQGLNPERVLFAVESVGLGFAALERATRYANERVVFGRPIGQNQGIAHPLAKSWAELSAAELLAYKAASLYDAGQDCGA
EANAAKYLGTEAGFTACETAVLTHGGMGYAKEYHVERMMREAMLARIAPVSREMILNFISERVLGLPKSY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=385, Percent_Identity=27.5324675324675, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI226958414, Length=358, Percent_Identity=28.7709497206704, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=27.7333333333333, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4557233, Length=362, Percent_Identity=30.939226519337, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI187960098, Length=339, Percent_Identity=30.0884955752212, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI4557231, Length=339, Percent_Identity=30.0884955752212, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI76496475, Length=381, Percent_Identity=29.3963254593176, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4557235, Length=381, Percent_Identity=29.3963254593176, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI7656849, Length=393, Percent_Identity=27.735368956743, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=24.5333333333333, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI21361497, Length=355, Percent_Identity=27.0422535211268, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4503943, Length=356, Percent_Identity=26.9662921348315, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=26.9662921348315, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI38505218, Length=301, Percent_Identity=25.9136212624585, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI87081958, Length=387, Percent_Identity=28.9405684754522, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1786223, Length=362, Percent_Identity=28.4530386740331, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI87082384, Length=278, Percent_Identity=27.3381294964029, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17569725, Length=390, Percent_Identity=29.7435897435897, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17534899, Length=348, Percent_Identity=30.7471264367816, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=27.6762402088773, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17508101, Length=381, Percent_Identity=27.0341207349081, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17538396, Length=365, Percent_Identity=28.2191780821918, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17506239, Length=381, Percent_Identity=25.4593175853018, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=28.0104712041885, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71990804, Length=298, Percent_Identity=28.1879194630872, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17505929, Length=379, Percent_Identity=25.3298153034301, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=379, Percent_Identity=24.5382585751979, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71985192, Length=316, Percent_Identity=27.5316455696203, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17534353, Length=360, Percent_Identity=26.1111111111111, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=25.8474576271186, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=356, Percent_Identity=24.438202247191, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71982178, Length=231, Percent_Identity=28.1385281385281, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=24.0816326530612, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=30.7065217391304, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24666513, Length=380, Percent_Identity=29.7368421052632, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281363737, Length=392, Percent_Identity=28.0612244897959, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=28.3783783783784, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355753, Length=376, Percent_Identity=28.9893617021277, Blast_Score=136, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24660351, Length=366, Percent_Identity=27.3224043715847, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI19920834, Length=354, Percent_Identity=25.7062146892655, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42603; Mature: 42603

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVIQPMTEDQAAIRDAVAKTLEPFDDAYWAKTDETGNWPEEFCNAMAKGGWLGIAFPEE
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCHH
YGGAGLGLTEAALMMQTVTRTGAGYSGASAIHLNIFGPKPLEKFGNPELKRESLPKIISG
HCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCCCCCCCHHHCCHHHCC
EEKMCFAVTEPNSGLDTSSLETKAERTNTGYMIHGRKIWTTGAQRADKILIIARTTPKDQ
CCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCEEEECCCCCCCEEEEEEECCCHHH
CAKPYMGLSLFYTDLNRNKIEANVIPKMGRKAVECNTLFIDGLEVPKEHLIGNEGDGFKY
HCCCCCCCEEEEEECCCCEEEECCCHHHCCCEEEEEEEEEECCCCCHHHHCCCCCCCHHH
LLQGLNPERVLFAVESVGLGFAALERATRYANERVVFGRPIGQNQGIAHPLAKSWAELSA
HHHCCCHHHEEEEEHHHCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHH
AELLAYKAASLYDAGQDCGAEANAAKYLGTEAGFTACETAVLTHGGMGYAKEYHVERMMR
HHHHHHHHHHHHHCCHHCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
EAMLARIAPVSREMILNFISERVLGLPKSY
HHHHHHHCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHVIQPMTEDQAAIRDAVAKTLEPFDDAYWAKTDETGNWPEEFCNAMAKGGWLGIAFPEE
CCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHCCCEEEEECCHH
YGGAGLGLTEAALMMQTVTRTGAGYSGASAIHLNIFGPKPLEKFGNPELKRESLPKIISG
HCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCCCCCCCHHHCCHHHCC
EEKMCFAVTEPNSGLDTSSLETKAERTNTGYMIHGRKIWTTGAQRADKILIIARTTPKDQ
CCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEECCEEEECCCCCCCEEEEEEECCCHHH
CAKPYMGLSLFYTDLNRNKIEANVIPKMGRKAVECNTLFIDGLEVPKEHLIGNEGDGFKY
HCCCCCCCEEEEEECCCCEEEECCCHHHCCCEEEEEEEEEECCCCCHHHHCCCCCCCHHH
LLQGLNPERVLFAVESVGLGFAALERATRYANERVVFGRPIGQNQGIAHPLAKSWAELSA
HHHCCCHHHEEEEEHHHCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHH
AELLAYKAASLYDAGQDCGAEANAAKYLGTEAGFTACETAVLTHGGMGYAKEYHVERMMR
HHHHHHHHHHHHHCCHHCCCCCCHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
EAMLARIAPVSREMILNFISERVLGLPKSY
HHHHHHHCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]