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The map label for this gene is pkn3 [H]

Identifier: 114797276

GI number: 114797276

Start: 1268227

End: 1270851

Strand: Direct

Name: pkn3 [H]

Synonym: HNE_1246

Alternate gene names: 114797276

Gene position: 1268227-1270851 (Clockwise)

Preceding gene: 114799288

Following gene: 114798527

Centisome position: 34.23

GC content: 68.5

Gene sequence:

>2625_bases
GTGGAGCTGGAGCGCCGGCCGCTGGAGGTGCTGAGCCTGCTGCTGCGCCATGCCGGGGAGGTGGTGACGAAGGAGGAGCT
GCTCGACACGGTCTGGCAGGGGCGGATCACGGTCGAGAATGTGCTGGCCAATGCCGTGGCCAAGCTGCGCAAGGGGCTGG
GCGAAGCGCTGGCCGAACACATCCGCACCCAGGCGCGCATCGGTTACCGCTTTACCGGGCCGGTGGAGCGGATCGCGGTG
GGGCGGGCGCTGGTCAACCGGCTGGACCTGCGCGCCGGGCAGCCCGTGCCGGGGCGCAGCCATTTCATGCTGAAGGAACA
GCTTTCCGGAACCAGGGGCAGCGAAGTGTGGCTGGCCCGGCATGACAAGACCGGGGAGCTGCGGGTTTACAAGTTCAGCC
CGGATGGCGCGCGGCTGGCCTCGCTGAAGCGGGAGGCGACGCTGGCGCGGGTGCTGCGCGAGAGCCTGGGCGAGCGGGAC
GATATTGCGCGGGTGATCGACTGGAATTTCGAGACGGCGCCGTTCTTTCTGGAATGCGCGTATGGCGGGGAGAACCTGCT
GGCATGGTCGCAGGGCGAGGGGCGGCTGGCGGCGATGTCGCAAGGGGCGCGGCTGGAGCTGGCGTTGCAGGCGATTGATG
TGGTGGGCGCCGCGCATGAGGCGGGGGTGCTGCACAAGGATCTGAAGCCGGCCAACTTTCTGGTGGCGCCGTGCCGGGAC
GGGGGCTGGCAGGTGCGCGTGACCGACTTTGGCGCGGGCGGGCTGGTGGAGCTGGGGCGGCTGGAAGACCTGGGCATCAC
GCCGATGGGGATGACGATTGAGGAAGGCGGCTCGGGCAGTTCCAGCCTCGGTACGCCGCTTTATATCGCGCCCGAGATCA
TCTCCGGGCAGGCGCCTTCGGCGCGGTGTGATGTCTATGCGCTGGGCGTGATGCTGTATCAGATCCTGGCCGGGGACATG
AAGAAGCCGCTGGCAACGGGTTGGGACGCGGACATCGATGATCCGCTGTTGCGCGAGGATATTGCCGAGGCGACGCATGG
CGATCCGTTGCAGCGGATTGCGTCTGCCGGGGAGCTGGCGGCGCGGCTGAGGGCGCTGGACGTGCGGCGGGAAGATCGCG
CGCGGGCGCAGGCGCTGGCGGCAGACGCCGAGGCGGCGCGGGCGGAGCTGGAGCGGGTGAAGACGCGGCGGCCCTGGGTG
GCGGCGACCTTTGCGGCGCTGGTGATCGGGTTTGGCGCGAGCGTGTGGCTGTACATGCAGGCGGAAGGCGCGCGGGGGCT
GGCGGAGACGCAGGCGGCGCGGGCCGAGGCGACGGGCGGGTTCCTGCGCGACCTGCTGGTGAATGCTGACCCCTACCGGC
CGGGCGGGGCGGGGGATGTGACGGTGCGCGCGGCGCTGGACAAGGCGGCGGCGGATATTGGCGCGCGGTTTGAAGATGAT
CCGGCTACGGAAGCCTCGATCCAGCAGACGGCGGGCGAGATCTATTCGAGCCTGGCGGTATATGATGCGGCCGCCGAGCG
GAAAGGGCGGGCGGCGGACCTGTTTGCGCGGCTGTATGGGGAAAGCGACCGGCGCACATTGCTGGCGCGGTATCTGCAGG
CCGAAGCGCTGGCCAATGCGTCCCGGATTGCGGACGCCGGGGCGGTGCTGGACATGGCGGACAAGGCGGCGATGGGGCAG
ACCGCTGGCGACGCGAAGCTGGCCTTTGCGGCGGCGCAGACGCGCGGGCGGTATTATCTCGTGCAGGCGAACATGGAGGA
ATCCGCGCCGTTTCTGGAGGCGGCGGTGCGGCTTCTGCCGGAGGCGATGCCTGAAGATGTGGAGGCGGGCTATCGGCTGA
AGATGGACCTTTCCCAGATTTACAGCCGCGTGGGCCGGCATGAAGACGCGATTGACCTGCTGGCGGGGTTGCAGGCGCCC
TCCTACGCTGAAGCGGGGGTGAGCGAGGCGACGCGGGCGCGGGCGAGCATGTTTCTGGGGGCATCGCTGTTTTATGCGGG
CAAGTATGATGAGGCTGAGCCGGTTCTGATAGAGTCCATCCGCCTGCTGACGGATGTGTTCGGAGAAGAAGCGGCGCAGG
TGGTGGAGGCGCAGAGCGCGCTGGCCAATCTTTATGCGACATCGGGGAACTGGGCGCCGGCGTTGCCGCTGGTGGCGGAT
GTGCGCGAGAAGATGTGCGCGCTGCACGGGGAGGACCATCTGACCTGCCTGATGACGATAGGAAATCAGGCGGTGTTCCA
GTGGTTCATGGATGACGCGGAGGGGGCGATTGCCAACCTTGTGCCGGTGGTGGAGACGTTTCGCGCGCAGCTGGGGCCGG
AGTCTCCGGCGGTGCATGTGATGGCGTATTATCTGGCGATGGCGAAGCTGGATGTGGGCGCGGCCGATGAAGCCCTGGCG
TTGGCGAATACGCTGGACGCGGCCAAGCTGGCAGCGGGCAGCCCAGGCGATGGCTGGGCCGAGCGCGTGGCCGGGCTGAA
GGGCATCGCGATGATCGATCAGGGGCAATGCGCGGCGGGGCTGGCGCTCCTGCGGCCTGCGGTCGAGGCGATGAAAGCCG
GAGACATGCAGCCCTGGATTCTGGCGGATTATGAAGAGGCCGAGGCTGGGGCGCCCTGCCGCTGA

Upstream 100 bases:

>100_bases
GGACGATTTCAAAAGCGAGGAACCCGCCCTCTACCGTTATCGCTTTGGCGCGGCGGAGTTTGACGAGGCGCGGTTTGACC
TGAAGGTGGGCGGGCTGGTT

Downstream 100 bases:

>100_bases
TTATCCGATGTCGGATATTCCCGTTTTTGCAAATTTCAGGATGGCGCCGGTGAGCCGGGCCAGGTCATCGTCGCTGATGC
CGTAGGCGGGGGAGAGGTAG

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 874; Mature: 874

Protein sequence:

>874_residues
MELERRPLEVLSLLLRHAGEVVTKEELLDTVWQGRITVENVLANAVAKLRKGLGEALAEHIRTQARIGYRFTGPVERIAV
GRALVNRLDLRAGQPVPGRSHFMLKEQLSGTRGSEVWLARHDKTGELRVYKFSPDGARLASLKREATLARVLRESLGERD
DIARVIDWNFETAPFFLECAYGGENLLAWSQGEGRLAAMSQGARLELALQAIDVVGAAHEAGVLHKDLKPANFLVAPCRD
GGWQVRVTDFGAGGLVELGRLEDLGITPMGMTIEEGGSGSSSLGTPLYIAPEIISGQAPSARCDVYALGVMLYQILAGDM
KKPLATGWDADIDDPLLREDIAEATHGDPLQRIASAGELAARLRALDVRREDRARAQALAADAEAARAELERVKTRRPWV
AATFAALVIGFGASVWLYMQAEGARGLAETQAARAEATGGFLRDLLVNADPYRPGGAGDVTVRAALDKAAADIGARFEDD
PATEASIQQTAGEIYSSLAVYDAAAERKGRAADLFARLYGESDRRTLLARYLQAEALANASRIADAGAVLDMADKAAMGQ
TAGDAKLAFAAAQTRGRYYLVQANMEESAPFLEAAVRLLPEAMPEDVEAGYRLKMDLSQIYSRVGRHEDAIDLLAGLQAP
SYAEAGVSEATRARASMFLGASLFYAGKYDEAEPVLIESIRLLTDVFGEEAAQVVEAQSALANLYATSGNWAPALPLVAD
VREKMCALHGEDHLTCLMTIGNQAVFQWFMDDAEGAIANLVPVVETFRAQLGPESPAVHVMAYYLAMAKLDVGAADEALA
LANTLDAAKLAAGSPGDGWAERVAGLKGIAMIDQGQCAAGLALLRPAVEAMKAGDMQPWILADYEEAEAGAPCR

Sequences:

>Translated_874_residues
MELERRPLEVLSLLLRHAGEVVTKEELLDTVWQGRITVENVLANAVAKLRKGLGEALAEHIRTQARIGYRFTGPVERIAV
GRALVNRLDLRAGQPVPGRSHFMLKEQLSGTRGSEVWLARHDKTGELRVYKFSPDGARLASLKREATLARVLRESLGERD
DIARVIDWNFETAPFFLECAYGGENLLAWSQGEGRLAAMSQGARLELALQAIDVVGAAHEAGVLHKDLKPANFLVAPCRD
GGWQVRVTDFGAGGLVELGRLEDLGITPMGMTIEEGGSGSSSLGTPLYIAPEIISGQAPSARCDVYALGVMLYQILAGDM
KKPLATGWDADIDDPLLREDIAEATHGDPLQRIASAGELAARLRALDVRREDRARAQALAADAEAARAELERVKTRRPWV
AATFAALVIGFGASVWLYMQAEGARGLAETQAARAEATGGFLRDLLVNADPYRPGGAGDVTVRAALDKAAADIGARFEDD
PATEASIQQTAGEIYSSLAVYDAAAERKGRAADLFARLYGESDRRTLLARYLQAEALANASRIADAGAVLDMADKAAMGQ
TAGDAKLAFAAAQTRGRYYLVQANMEESAPFLEAAVRLLPEAMPEDVEAGYRLKMDLSQIYSRVGRHEDAIDLLAGLQAP
SYAEAGVSEATRARASMFLGASLFYAGKYDEAEPVLIESIRLLTDVFGEEAAQVVEAQSALANLYATSGNWAPALPLVAD
VREKMCALHGEDHLTCLMTIGNQAVFQWFMDDAEGAIANLVPVVETFRAQLGPESPAVHVMAYYLAMAKLDVGAADEALA
LANTLDAAKLAAGSPGDGWAERVAGLKGIAMIDQGQCAAGLALLRPAVEAMKAGDMQPWILADYEEAEAGAPCR
>Mature_874_residues
MELERRPLEVLSLLLRHAGEVVTKEELLDTVWQGRITVENVLANAVAKLRKGLGEALAEHIRTQARIGYRFTGPVERIAV
GRALVNRLDLRAGQPVPGRSHFMLKEQLSGTRGSEVWLARHDKTGELRVYKFSPDGARLASLKREATLARVLRESLGERD
DIARVIDWNFETAPFFLECAYGGENLLAWSQGEGRLAAMSQGARLELALQAIDVVGAAHEAGVLHKDLKPANFLVAPCRD
GGWQVRVTDFGAGGLVELGRLEDLGITPMGMTIEEGGSGSSSLGTPLYIAPEIISGQAPSARCDVYALGVMLYQILAGDM
KKPLATGWDADIDDPLLREDIAEATHGDPLQRIASAGELAARLRALDVRREDRARAQALAADAEAARAELERVKTRRPWV
AATFAALVIGFGASVWLYMQAEGARGLAETQAARAEATGGFLRDLLVNADPYRPGGAGDVTVRAALDKAAADIGARFEDD
PATEASIQQTAGEIYSSLAVYDAAAERKGRAADLFARLYGESDRRTLLARYLQAEALANASRIADAGAVLDMADKAAMGQ
TAGDAKLAFAAAQTRGRYYLVQANMEESAPFLEAAVRLLPEAMPEDVEAGYRLKMDLSQIYSRVGRHEDAIDLLAGLQAP
SYAEAGVSEATRARASMFLGASLFYAGKYDEAEPVLIESIRLLTDVFGEEAAQVVEAQSALANLYATSGNWAPALPLVAD
VREKMCALHGEDHLTCLMTIGNQAVFQWFMDDAEGAIANLVPVVETFRAQLGPESPAVHVMAYYLAMAKLDVGAADEALA
LANTLDAAKLAAGSPGDGWAERVAGLKGIAMIDQGQCAAGLALLRPAVEAMKAGDMQPWILADYEEAEAGAPCR

Specific function: Required For Pcad Induction, A Promoter Upstream Of Cadb That Is Responsible For The Ph-Regulated Expression Of Cada. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI14196445, Length=224, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI134304838, Length=133, Percent_Identity=31.5789473684211, Blast_Score=73, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320698, Length=345, Percent_Identity=24.0579710144928, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324472, Length=149, Percent_Identity=30.2013422818792, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271
- InterPro:   IPR002290 [H]

Pfam domain/function: PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 93563; Mature: 93563

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELERRPLEVLSLLLRHAGEVVTKEELLDTVWQGRITVENVLANAVAKLRKGLGEALAEH
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IRTQARIGYRFTGPVERIAVGRALVNRLDLRAGQPVPGRSHFMLKEQLSGTRGSEVWLAR
HHHHHHCCEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEEEE
HDKTGELRVYKFSPDGARLASLKREATLARVLRESLGERDDIARVIDWNFETAPFFLECA
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEE
YGGENLLAWSQGEGRLAAMSQGARLELALQAIDVVGAAHEAGVLHKDLKPANFLVAPCRD
CCCCCEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEECCC
GGWQVRVTDFGAGGLVELGRLEDLGITPMGMTIEEGGSGSSSLGTPLYIAPEIISGQAPS
CCEEEEEEECCCCCCEECCCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCHHHCCCCCC
ARCDVYALGVMLYQILAGDMKKPLATGWDADIDDPLLREDIAEATHGDPLQRIASAGELA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
ARLRALDVRREDRARAQALAADAEAARAELERVKTRRPWVAATFAALVIGFGASVWLYMQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEE
AEGARGLAETQAARAEATGGFLRDLLVNADPYRPGGAGDVTVRAALDKAAADIGARFEDD
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCC
PATEASIQQTAGEIYSSLAVYDAAAERKGRAADLFARLYGESDRRTLLARYLQAEALANA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SRIADAGAVLDMADKAAMGQTAGDAKLAFAAAQTRGRYYLVQANMEESAPFLEAAVRLLP
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
EAMPEDVEAGYRLKMDLSQIYSRVGRHEDAIDLLAGLQAPSYAEAGVSEATRARASMFLG
HHCCCHHCCCCEEEECHHHHHHHHCCCCHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHH
ASLFYAGKYDEAEPVLIESIRLLTDVFGEEAAQVVEAQSALANLYATSGNWAPALPLVAD
HHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
VREKMCALHGEDHLTCLMTIGNQAVFQWFMDDAEGAIANLVPVVETFRAQLGPESPAVHV
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHH
MAYYLAMAKLDVGAADEALALANTLDAAKLAAGSPGDGWAERVAGLKGIAMIDQGQCAAG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEECCCCHHHH
LALLRPAVEAMKAGDMQPWILADYEEAEAGAPCR
HHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCC
>Mature Secondary Structure
MELERRPLEVLSLLLRHAGEVVTKEELLDTVWQGRITVENVLANAVAKLRKGLGEALAEH
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IRTQARIGYRFTGPVERIAVGRALVNRLDLRAGQPVPGRSHFMLKEQLSGTRGSEVWLAR
HHHHHHCCEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCEEEEEE
HDKTGELRVYKFSPDGARLASLKREATLARVLRESLGERDDIARVIDWNFETAPFFLECA
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEE
YGGENLLAWSQGEGRLAAMSQGARLELALQAIDVVGAAHEAGVLHKDLKPANFLVAPCRD
CCCCCEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHCCCCCCEEEEECCC
GGWQVRVTDFGAGGLVELGRLEDLGITPMGMTIEEGGSGSSSLGTPLYIAPEIISGQAPS
CCEEEEEEECCCCCCEECCCCCCCCCCCCCCEEECCCCCCCCCCCCEEECCHHHCCCCCC
ARCDVYALGVMLYQILAGDMKKPLATGWDADIDDPLLREDIAEATHGDPLQRIASAGELA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
ARLRALDVRREDRARAQALAADAEAARAELERVKTRRPWVAATFAALVIGFGASVWLYMQ
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEE
AEGARGLAETQAARAEATGGFLRDLLVNADPYRPGGAGDVTVRAALDKAAADIGARFEDD
ECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCC
PATEASIQQTAGEIYSSLAVYDAAAERKGRAADLFARLYGESDRRTLLARYLQAEALANA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
SRIADAGAVLDMADKAAMGQTAGDAKLAFAAAQTRGRYYLVQANMEESAPFLEAAVRLLP
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
EAMPEDVEAGYRLKMDLSQIYSRVGRHEDAIDLLAGLQAPSYAEAGVSEATRARASMFLG
HHCCCHHCCCCEEEECHHHHHHHHCCCCHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHH
ASLFYAGKYDEAEPVLIESIRLLTDVFGEEAAQVVEAQSALANLYATSGNWAPALPLVAD
HHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
VREKMCALHGEDHLTCLMTIGNQAVFQWFMDDAEGAIANLVPVVETFRAQLGPESPAVHV
HHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHH
MAYYLAMAKLDVGAADEALALANTLDAAKLAAGSPGDGWAERVAGLKGIAMIDQGQCAAG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEECCCCHHHH
LALLRPAVEAMKAGDMQPWILADYEEAEAGAPCR
HHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA