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The map label for this gene is degS [H]

Identifier: 114797196

GI number: 114797196

Start: 1558670

End: 1559731

Strand: Direct

Name: degS [H]

Synonym: HNE_1525

Alternate gene names: 114797196

Gene position: 1558670-1559731 (Clockwise)

Preceding gene: 114798819

Following gene: 114798738

Centisome position: 42.07

GC content: 63.09

Gene sequence:

>1062_bases
ATGCAGTCAGAAACCGTTTCCGCCCTGCGGGATCTCTACAGGGCCTCGGAGGCGCGCGCGGCGCGCCTGACCCTGCTATT
TGAGGCGGGCCGTGACCTGGCTTTCGCCGATGCTGCCAGCCTCAGCGCGACCCTGTCCCAATGTGCTCGCCGGGCGGCCC
TTTTTGCGGGCGCTGCGGAGGGGCAGGTGATCTTCGCCGACGGAGAAGGCATTCCCCTGATCGCGCCCGGCCCGGCTGCC
CGGCGAGTCGGCACTCTGATCATTGAAGACTGGGAGAACCGGAAGCGTTTCTCCGATGAAGAAGATCGCGGCGCACTGGA
TCTGCTCGCCGGACTGATGGCGACAGCCATCGACCGCATCGATCGCGTGCGCGAGCGGGAAGACCTGCTCGGTAAACTCA
AAGAGCGCGAACGTCAGCTGGAGCATCTGGTCGGGCGGATATTTACCAGCCAGGAAGACGAGCGCCGCCGGGTTGCGCAT
GATCTCCATGATGGAGTTGCCCAGACGGCTGCCGCCCTGTTCCGCAGGCTGGACGCCCTGACGGAGCGCTCATCTGGGAG
CGAAGCCGCTGCGCTCGCGCCGATCGCAAGGTCCCTTGTGGGAGAGCTTCGCGGGGTGATTGCGGGCTTGAGGCCAACAG
CGCTCGACGATCTGGGAATCAGCGCAGCCATCTCGTCAATGGCGGACGGCCTGCGCGAAGACGGGTATGAAGTCACCTTC
CGGCAGGCCGGGCCAGATCGCTGGCCCCCTGTCATTGAAACGGCGTTTTTCAGGATTGTGCAGGAAGCGCTCACCAACAT
TCGCAAGCATGCCGGTGGGCCATGCCAGGTTGATATTGTTCTCTCAGCTGAGCCTGATTCTGCGCGTTGGCATTTGAGCG
TCAGGGATGGCGGGAAGGGGCTTGCGAGCGAGAAAAATAGAGATGTGAGCAAAAAGGGACAGAAAATCGGCCTTGAGATC
ATGCGTGAGCGGATGATGGCCCTGGGGGGCGAGCTTCAGGTTGGAGCTGGTCGCGACGGCGGTACAGAGGTTCGTGCCTG
TCTCGAGAGGGTGCCGGAATGA

Upstream 100 bases:

>100_bases
CTAAGCCGGATGGCTAACCAGATTACCTAGGCCGTTCGGCCTATGCCGTGCCGCCTGTGCGCCCTAAATAAGTGGTCAGG
AATAGCAGGCAGCCTCTAAG

Downstream 100 bases:

>100_bases
ACCCGCCGCCCCGCATTCTGGTTGTGGATGATCATGCGCTTGCCCGGGAAGGATTGCGGGCAATCCTGCTTGCTGCCGGA
TATGACGTGGTCGGAGAAGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MQSETVSALRDLYRASEARAARLTLLFEAGRDLAFADAASLSATLSQCARRAALFAGAAEGQVIFADGEGIPLIAPGPAA
RRVGTLIIEDWENRKRFSDEEDRGALDLLAGLMATAIDRIDRVREREDLLGKLKERERQLEHLVGRIFTSQEDERRRVAH
DLHDGVAQTAAALFRRLDALTERSSGSEAAALAPIARSLVGELRGVIAGLRPTALDDLGISAAISSMADGLREDGYEVTF
RQAGPDRWPPVIETAFFRIVQEALTNIRKHAGGPCQVDIVLSAEPDSARWHLSVRDGGKGLASEKNRDVSKKGQKIGLEI
MRERMMALGGELQVGAGRDGGTEVRACLERVPE

Sequences:

>Translated_353_residues
MQSETVSALRDLYRASEARAARLTLLFEAGRDLAFADAASLSATLSQCARRAALFAGAAEGQVIFADGEGIPLIAPGPAA
RRVGTLIIEDWENRKRFSDEEDRGALDLLAGLMATAIDRIDRVREREDLLGKLKERERQLEHLVGRIFTSQEDERRRVAH
DLHDGVAQTAAALFRRLDALTERSSGSEAAALAPIARSLVGELRGVIAGLRPTALDDLGISAAISSMADGLREDGYEVTF
RQAGPDRWPPVIETAFFRIVQEALTNIRKHAGGPCQVDIVLSAEPDSARWHLSVRDGGKGLASEKNRDVSKKGQKIGLEI
MRERMMALGGELQVGAGRDGGTEVRACLERVPE
>Mature_353_residues
MQSETVSALRDLYRASEARAARLTLLFEAGRDLAFADAASLSATLSQCARRAALFAGAAEGQVIFADGEGIPLIAPGPAA
RRVGTLIIEDWENRKRFSDEEDRGALDLLAGLMATAIDRIDRVREREDLLGKLKERERQLEHLVGRIFTSQEDERRRVAH
DLHDGVAQTAAALFRRLDALTERSSGSEAAALAPIARSLVGELRGVIAGLRPTALDDLGISAAISSMADGLREDGYEVTF
RQAGPDRWPPVIETAFFRIVQEALTNIRKHAGGPCQVDIVLSAEPDSARWHLSVRDGGKGLASEKNRDVSKKGQKIGLEI
MRERMMALGGELQVGAGRDGGTEVRACLERVPE

Specific function: Involved in a sensory transduction pathway that affect the production of enzymes that degrade polymeric carbon and nitrogen sources. DegS probably acts as a kinase that phosphorylates degU [H]

COG id: COG4564

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR008595
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR016381 [H]

Pfam domain/function: PF05384 DegS; PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38312; Mature: 38312

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSETVSALRDLYRASEARAARLTLLFEAGRDLAFADAASLSATLSQCARRAALFAGAAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GQVIFADGEGIPLIAPGPAARRVGTLIIEDWENRKRFSDEEDRGALDLLAGLMATAIDRI
CEEEEECCCCCEEECCCHHHHHHHHHHEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DRVREREDLLGKLKERERQLEHLVGRIFTSQEDERRRVAHDLHDGVAQTAAALFRRLDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TERSSGSEAAALAPIARSLVGELRGVIAGLRPTALDDLGISAAISSMADGLREDGYEVTF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
RQAGPDRWPPVIETAFFRIVQEALTNIRKHAGGPCQVDIVLSAEPDSARWHLSVRDGGKG
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCC
LASEKNRDVSKKGQKIGLEIMRERMMALGGELQVGAGRDGGTEVRACLERVPE
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MQSETVSALRDLYRASEARAARLTLLFEAGRDLAFADAASLSATLSQCARRAALFAGAAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GQVIFADGEGIPLIAPGPAARRVGTLIIEDWENRKRFSDEEDRGALDLLAGLMATAIDRI
CEEEEECCCCCEEECCCHHHHHHHHHHEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DRVREREDLLGKLKERERQLEHLVGRIFTSQEDERRRVAHDLHDGVAQTAAALFRRLDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TERSSGSEAAALAPIARSLVGELRGVIAGLRPTALDDLGISAAISSMADGLREDGYEVTF
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEE
RQAGPDRWPPVIETAFFRIVQEALTNIRKHAGGPCQVDIVLSAEPDSARWHLSVRDGGKG
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEEECCCCCC
LASEKNRDVSKKGQKIGLEIMRERMMALGGELQVGAGRDGGTEVRACLERVPE
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]