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The map label for this gene is exuR [H]

Identifier: 114797136

GI number: 114797136

Start: 1130511

End: 1131551

Strand: Direct

Name: exuR [H]

Synonym: HNE_1121

Alternate gene names: 114797136

Gene position: 1130511-1131551 (Clockwise)

Preceding gene: 114798154

Following gene: 114798036

Centisome position: 30.51

GC content: 63.4

Gene sequence:

>1041_bases
GTGCAGGAAGCCGCAGAATTCAAGCTTCAGGGCCGGGCTACGATCAACGACATCGCGCGCATCGCGAAGGTGTCGAAGAA
AACGGTCTCTCGTGTCATCAATGACAGCCCGCTGGTCAAACAGCGCACCCGCGAAGTCGTAAAGGCTATCATTGCCGAGC
TGGGCTATACGCCAGATCCGCAGGCGCGCGCTCTGGCGCTGCGGCGGTCGTTTCTGGTCGGCCTGGTCTATGACAGTCCC
AGCCCGCAATATGTCGTCAACATGCAGCGCGGTATCCTGGACGCGCTTGAGGATACCGATTTCCAGCTTGTGCTGCGCCC
GGTCAGCCGCACGGACGCAAACTATCCTGGCCGCCTCCGCCAGTTCATCCAGCACCACAAGCCGTTTGGCCTCATCCTGC
CGCCGTCGGTGTCCGAGGATGAAGAGTTGTCTCAGATGTTCCGGGATCATGATGTCGACTATGTGCGCATCGCGTCTGGC
ATGCTGGACGCGCCCGCGCGGATGATACTGACCCATGACGGCGAAGGCGCGGCCCAGGCGGCGCGCCATTTGTGCGCGCT
GGGGCATACGGACATTGCCCATATCCATGGCCCGGAATCGTTCCGCTGCGCGCATGAGCGCCGCAGCGGGTTCCAGCGCG
GCCTTGCCGAGGCGGGTGTTACGCTTCATCCCGAGCTTACGGTCGAGGCGGGGTATACGTTCGACTCGGGCCTTCTGGCC
ATGGAGCGCCTGCTTTACGGAAAGCGCCGCCCCACGGCCGTATTTGCGGGCAATGACGAGATGGCAACGGGCGTTTATGT
CGCCGTGCGCAAGGCCGGCCTGCGTATTCCTGAAGATGTGTCCATCGTCGGTTTCGACGACACGCCGATTGCAGGGCGCC
TTTGGCCGGCGCTGACAACCGTGCGGCTGCCGATCCGCGAAATGGGACATGCGGCCGCCCGTCTACTGCTCGACCAGGCT
GCGGGGATCGAGCGCGAAGAGGTCACCAGCTTCACGCCGGAGATAATCGTGCGCGAGTCAACCGCCGCGCCGCTCAGATG
A

Upstream 100 bases:

>100_bases
ATGTCCACCACCGGGCAAAAGAGGACATTCCATTCTCAAACAAGGGTTTCCGGTGAGCGACAATTCAAAACCCGACCTCG
AAGCCGAAATCGCGGCCGCC

Downstream 100 bases:

>100_bases
CGCGCCGCTAAGGAGGGGGCCTGCATATCTCTGAAGCGGGTCGCCATAGCTTGGGGCTTTGCGGCGTGGATCGTACGCCG
CGTCAGTCCTGGCCCTCGCT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MQEAAEFKLQGRATINDIARIAKVSKKTVSRVINDSPLVKQRTREVVKAIIAELGYTPDPQARALALRRSFLVGLVYDSP
SPQYVVNMQRGILDALEDTDFQLVLRPVSRTDANYPGRLRQFIQHHKPFGLILPPSVSEDEELSQMFRDHDVDYVRIASG
MLDAPARMILTHDGEGAAQAARHLCALGHTDIAHIHGPESFRCAHERRSGFQRGLAEAGVTLHPELTVEAGYTFDSGLLA
MERLLYGKRRPTAVFAGNDEMATGVYVAVRKAGLRIPEDVSIVGFDDTPIAGRLWPALTTVRLPIREMGHAAARLLLDQA
AGIEREEVTSFTPEIIVRESTAAPLR

Sequences:

>Translated_346_residues
MQEAAEFKLQGRATINDIARIAKVSKKTVSRVINDSPLVKQRTREVVKAIIAELGYTPDPQARALALRRSFLVGLVYDSP
SPQYVVNMQRGILDALEDTDFQLVLRPVSRTDANYPGRLRQFIQHHKPFGLILPPSVSEDEELSQMFRDHDVDYVRIASG
MLDAPARMILTHDGEGAAQAARHLCALGHTDIAHIHGPESFRCAHERRSGFQRGLAEAGVTLHPELTVEAGYTFDSGLLA
MERLLYGKRRPTAVFAGNDEMATGVYVAVRKAGLRIPEDVSIVGFDDTPIAGRLWPALTTVRLPIREMGHAAARLLLDQA
AGIEREEVTSFTPEIIVRESTAAPLR
>Mature_346_residues
MQEAAEFKLQGRATINDIARIAKVSKKTVSRVINDSPLVKQRTREVVKAIIAELGYTPDPQARALALRRSFLVGLVYDSP
SPQYVVNMQRGILDALEDTDFQLVLRPVSRTDANYPGRLRQFIQHHKPFGLILPPSVSEDEELSQMFRDHDVDYVRIASG
MLDAPARMILTHDGEGAAQAARHLCALGHTDIAHIHGPESFRCAHERRSGFQRGLAEAGVTLHPELTVEAGYTFDSGLLA
MERLLYGKRRPTAVFAGNDEMATGVYVAVRKAGLRIPEDVSIVGFDDTPIAGRLWPALTTVRLPIREMGHAAARLLLDQA
AGIEREEVTSFTPEIIVRESTAAPLR

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=346, Percent_Identity=32.6589595375723, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790194, Length=305, Percent_Identity=31.8032786885246, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1788474, Length=331, Percent_Identity=34.441087613293, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789202, Length=335, Percent_Identity=32.8358208955224, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1790369, Length=346, Percent_Identity=29.4797687861272, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786540, Length=346, Percent_Identity=28.6127167630058, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789068, Length=335, Percent_Identity=27.1641791044776, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787580, Length=318, Percent_Identity=27.6729559748428, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994940, Length=333, Percent_Identity=24.3243243243243, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787906, Length=308, Percent_Identity=24.6753246753247, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790689, Length=322, Percent_Identity=25.776397515528, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38215; Mature: 38215

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEAAEFKLQGRATINDIARIAKVSKKTVSRVINDSPLVKQRTREVVKAIIAELGYTPDP
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
QARALALRRSFLVGLVYDSPSPQYVVNMQRGILDALEDTDFQLVLRPVSRTDANYPGRLR
HHHHHHHHHHHHEEEEECCCCCCEEEEHHHHHHHHHCCCCEEEEEEEHHHCCCCCCHHHH
QFIQHHKPFGLILPPSVSEDEELSQMFRDHDVDYVRIASGMLDAPARMILTHDGEGAAQA
HHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEHHHCHHCCCCEEEEEECCCCHHHH
ARHLCALGHTDIAHIHGPESFRCAHERRSGFQRGLAEAGVTLHPELTVEAGYTFDSGLLA
HHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCHHHHH
MERLLYGKRRPTAVFAGNDEMATGVYVAVRKAGLRIPEDVSIVGFDDTPIAGRLWPALTT
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHH
VRLPIREMGHAAARLLLDQAAGIEREEVTSFTPEIIVRESTAAPLR
HCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MQEAAEFKLQGRATINDIARIAKVSKKTVSRVINDSPLVKQRTREVVKAIIAELGYTPDP
CCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCC
QARALALRRSFLVGLVYDSPSPQYVVNMQRGILDALEDTDFQLVLRPVSRTDANYPGRLR
HHHHHHHHHHHHEEEEECCCCCCEEEEHHHHHHHHHCCCCEEEEEEEHHHCCCCCCHHHH
QFIQHHKPFGLILPPSVSEDEELSQMFRDHDVDYVRIASGMLDAPARMILTHDGEGAAQA
HHHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEHHHCHHCCCCEEEEEECCCCHHHH
ARHLCALGHTDIAHIHGPESFRCAHERRSGFQRGLAEAGVTLHPELTVEAGYTFDSGLLA
HHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCHHHHH
MERLLYGKRRPTAVFAGNDEMATGVYVAVRKAGLRIPEDVSIVGFDDTPIAGRLWPALTT
HHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHH
VRLPIREMGHAAARLLLDQAAGIEREEVTSFTPEIIVRESTAAPLR
HCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]